메뉴 건너뛰기




Volumn 17, Issue 9, 2015, Pages 684-693

Identification of circulating MicroRNAs as novel potential biomarkers for hepatocellular carcinoma detection: a systematic review and meta-analysis

Author keywords

Hepatocellular carcinoma; Meta analysis; MicroRNA; Systematic review

Indexed keywords

MICRORNA; MICRORNA 122; MICRORNA 21; MICRORNA 223; TUMOR MARKER;

EID: 84938985185     PISSN: 1699048X     EISSN: 16993055     Source Type: Journal    
DOI: 10.1007/s12094-015-1294-y     Document Type: Review
Times cited : (40)

References (58)
  • 1
    • 79952277505 scopus 로고    scopus 로고
    • The incidence and epidemiology of hepatocellular carcinoma: a global and regional perspective
    • PID: 21115576
    • Venook AP, Papandreou C, Furuse J, de Guevara LL. The incidence and epidemiology of hepatocellular carcinoma: a global and regional perspective. Oncologist. 2010;15(Suppl 4):5–13. doi:10.1634/theoncologist.2010-S4-05.
    • (2010) Oncologist , vol.15 , pp. 5-13
    • Venook, A.P.1    Papandreou, C.2    Furuse, J.3    de Guevara, L.L.4
  • 3
    • 84859212951 scopus 로고    scopus 로고
    • Hepatocellular carcinoma
    • PID: 22353262
    • Forner A, Llovet JM, Bruix J. Hepatocellular carcinoma. Lancet. 2012;379(9822):1245–55. doi:10.1016/s0140-6736(11)61347-0.
    • (2012) Lancet , vol.379 , Issue.9822 , pp. 1245-1255
    • Forner, A.1    Llovet, J.M.2    Bruix, J.3
  • 4
    • 84869884245 scopus 로고    scopus 로고
    • Biomarkers for hepatocellular carcinoma
    • PID: 22655201
    • Behne T, Copur MS. Biomarkers for hepatocellular carcinoma. Int J Hepatol. 2012;2012:859076. doi:10.1155/2012/859076.
    • (2012) Int J Hepatol , vol.2012 , pp. 859076
    • Behne, T.1    Copur, M.S.2
  • 5
    • 84864438094 scopus 로고    scopus 로고
    • New serum markers of hepatocellular carcinoma
    • COI: 1:CAS:528:DC%2BC38XhtFeis7bL, PID: 22846860
    • Masuzaki R, Karp SJ, Omata M. New serum markers of hepatocellular carcinoma. Semin Oncol. 2012;39(4):434–9. doi:10.1053/j.seminoncol.2012.05.009.
    • (2012) Semin Oncol , vol.39 , Issue.4 , pp. 434-439
    • Masuzaki, R.1    Karp, S.J.2    Omata, M.3
  • 6
    • 84870403118 scopus 로고    scopus 로고
    • GP73 expression and its significance in the diagnosis of hepatocellular carcinoma: a review
    • COI: 1:CAS:528:DC%2BC38XhslamurvO, PID: 23119104
    • Ba MC, Long H, Tang YQ, Cui SZ. GP73 expression and its significance in the diagnosis of hepatocellular carcinoma: a review. Int J Clin Exp Pathol. 2012;5(9):874–81.
    • (2012) Int J Clin Exp Pathol , vol.5 , Issue.9 , pp. 874-881
    • Ba, M.C.1    Long, H.2    Tang, Y.Q.3    Cui, S.Z.4
  • 7
    • 84878826126 scopus 로고    scopus 로고
    • Aberrant microRNAs expression patterns in pancreatic cancer and their clinical translation
    • COI: 1:CAS:528:DC%2BC3sXpt1ertLk%3D, PID: 23621126
    • Du Y, Liu M, Gao J, Li Z. Aberrant microRNAs expression patterns in pancreatic cancer and their clinical translation. Cancer Biother Radiopharm. 2013;28(5):361–9. doi:10.1089/cbr.2012.1389.
    • (2013) Cancer Biother Radiopharm , vol.28 , Issue.5 , pp. 361-369
    • Du, Y.1    Liu, M.2    Gao, J.3    Li, Z.4
  • 8
    • 84864857745 scopus 로고    scopus 로고
    • New biomarkers and targets in pancreatic cancer and their application to treatment
    • COI: 1:CAS:528:DC%2BC38XhtFKjtbfO, PID: 22733351
    • Costello E, Greenhalf W, Neoptolemos JP. New biomarkers and targets in pancreatic cancer and their application to treatment. Nat Rev Gastroenterol Hepatol. 2012;9(8):435–44. doi:10.1038/nrgastro.2012.119.
    • (2012) Nat Rev Gastroenterol Hepatol , vol.9 , Issue.8 , pp. 435-444
    • Costello, E.1    Greenhalf, W.2    Neoptolemos, J.P.3
  • 9
    • 27744537851 scopus 로고    scopus 로고
    • Human RISC couples microRNA biogenesis and posttranscriptional gene silencing
    • COI: 1:CAS:528:DC%2BD2MXht1yktrjN, PID: 16271387
    • Gregory RI, Chendrimada TP, Cooch N, Shiekhattar R. Human RISC couples microRNA biogenesis and posttranscriptional gene silencing. Cell. 2005;123(4):631–40. doi:10.1016/j.cell.2005.10.022.
    • (2005) Cell , vol.123 , Issue.4 , pp. 631-640
    • Gregory, R.I.1    Chendrimada, T.P.2    Cooch, N.3    Shiekhattar, R.4
  • 10
    • 84876939170 scopus 로고    scopus 로고
    • The long and short of microRNA
    • COI: 1:CAS:528:DC%2BC3sXmsleqs78%3D, PID: 23622238
    • Yates LA, Norbury CJ, Gilbert RJ. The long and short of microRNA. Cell. 2013;153(3):516–9. doi:10.1016/j.cell.2013.04.003.
    • (2013) Cell , vol.153 , Issue.3 , pp. 516-519
    • Yates, L.A.1    Norbury, C.J.2    Gilbert, R.J.3
  • 12
    • 48749122914 scopus 로고    scopus 로고
    • Circulating microRNAs as stable blood-based markers for cancer detection
    • COI: 1:CAS:528:DC%2BD1cXpsVCltL0%3D, PID: 18663219
    • Mitchell PS, Parkin RK, Kroh EM, Fritz BR, Wyman SK, Pogosova-Agadjanyan EL, et al. Circulating microRNAs as stable blood-based markers for cancer detection. Proc Natl Acad Sci USA. 2008;105(30):10513–8. doi:10.1073/pnas.0804549105.
    • (2008) Proc Natl Acad Sci USA , vol.105 , Issue.30 , pp. 10513-10518
    • Mitchell, P.S.1    Parkin, R.K.2    Kroh, E.M.3    Fritz, B.R.4    Wyman, S.K.5    Pogosova-Agadjanyan, E.L.6
  • 13
    • 43449102192 scopus 로고    scopus 로고
    • Detection of elevated levels of tumour-associated microRNAs in serum of patients with diffuse large B-cell lymphoma
    • PID: 18318758
    • Lawrie CH, Gal S, Dunlop HM, Pushkaran B, Liggins AP, Pulford K, et al. Detection of elevated levels of tumour-associated microRNAs in serum of patients with diffuse large B-cell lymphoma. Br J Haematol. 2008;141(5):672–5. doi:10.1111/j.1365-2141.2008.07077.x.
    • (2008) Br J Haematol , vol.141 , Issue.5 , pp. 672-675
    • Lawrie, C.H.1    Gal, S.2    Dunlop, H.M.3    Pushkaran, B.4    Liggins, A.P.5    Pulford, K.6
  • 14
    • 33750943691 scopus 로고    scopus 로고
    • Meta-analysis and meta-review of thyroid cancer gene expression profiling studies identifies important diagnostic biomarkers
    • COI: 1:CAS:528:DC%2BD28Xht1Gnur3M
    • Griffith OL, Melck A, Jones SJ, Wiseman SM. Meta-analysis and meta-review of thyroid cancer gene expression profiling studies identifies important diagnostic biomarkers. J Clin Oncol Off J Am Soc Clin Oncol. 2006;24(31):5043–51. doi:10.1200/jco.2006.06.7330.
    • (2006) J Clin Oncol Off J Am Soc Clin Oncol , vol.24 , Issue.31 , pp. 5043-5051
    • Griffith, O.L.1    Melck, A.2    Jones, S.J.3    Wiseman, S.M.4
  • 16
    • 2942700307 scopus 로고    scopus 로고
    • The development of QUADAS: a tool for the quality assessment of studies of diagnostic accuracy included in systematic reviews
    • PID: 14606960
    • Whiting P, Rutjes AW, Reitsma JB, Bossuyt PM, Kleijnen J. The development of QUADAS: a tool for the quality assessment of studies of diagnostic accuracy included in systematic reviews. BMC Med Res Methodol. 2003;3:25. doi:10.1186/1471-2288-3-25.
    • (2003) BMC Med Res Methodol , vol.3 , pp. 25
    • Whiting, P.1    Rutjes, A.W.2    Reitsma, J.B.3    Bossuyt, P.M.4    Kleijnen, J.5
  • 17
    • 0027715844 scopus 로고
    • Estimating diagnostic accuracy from multiple conflicting reports: a new meta-analytic method
    • COI: 1:STN:280:DyaK2c%2Fms1OisQ%3D%3D
    • Littenberg B, Moses LE. Estimating diagnostic accuracy from multiple conflicting reports: a new meta-analytic method. Med Dec Making An Int J Soc Med Dec Making. 1993;13(4):313–21.
    • (1993) Med Dec Making An Int J Soc Med Dec Making , vol.13 , Issue.4 , pp. 313-321
    • Littenberg, B.1    Moses, L.E.2
  • 18
    • 0030922816 scopus 로고    scopus 로고
    • Bias in meta-analysis detected by a simple, graphical test
    • COI: 1:STN:280:DyaK2svls1KjtA%3D%3D
    • Egger M, Davey Smith G, Schneider M, Minder C. Bias in meta-analysis detected by a simple, graphical test. BMJ Clin Res Ed. 1997;315(7109):629–34.
    • (1997) BMJ Clin Res Ed , vol.315 , Issue.7109 , pp. 629-634
    • Egger, M.1    Davey Smith, G.2    Schneider, M.3    Minder, C.4
  • 20
    • 84871963876 scopus 로고    scopus 로고
    • Promising Candidate Urinary MicroRNA Biomarkers for the Early Detection of Hepatocellular Carcinoma among High-Risk Hepatitis C Virus Egyptian Patients
    • COI: 1:CAS:528:DC%2BC38XlvFeruw%3D%3D, PID: 22211142
    • Abdalla MA, Haj-Ahmad Y. Promising Candidate Urinary MicroRNA Biomarkers for the Early Detection of Hepatocellular Carcinoma among High-Risk Hepatitis C Virus Egyptian Patients. J Cancer. 2012;3:19–31.
    • (2012) J Cancer , vol.3 , pp. 19-31
    • Abdalla, M.A.1    Haj-Ahmad, Y.2
  • 21
    • 80055103381 scopus 로고    scopus 로고
    • Serum microRNA-21 as marker for necroinflammation in hepatitis C patients with and without hepatocellular carcinoma
    • COI: 1:CAS:528:DC%2BC3MXhsV2ltbbF, PID: 22066022
    • Bihrer V, Waidmann O, Friedrich-Rust M, Forestier N, Susser S, Haupenthal J, et al. Serum microRNA-21 as marker for necroinflammation in hepatitis C patients with and without hepatocellular carcinoma. PLoS ONE. 2011;6(10):e26971. doi:10.1371/journal.pone.0026971.
    • (2011) PLoS ONE , vol.6 , Issue.10 , pp. 26971
    • Bihrer, V.1    Waidmann, O.2    Friedrich-Rust, M.3    Forestier, N.4    Susser, S.5    Haupenthal, J.6
  • 22
    • 84886802057 scopus 로고    scopus 로고
    • Circulating microRNA-101 as a potential biomarker for hepatitis B virus-related hepatocellular carcinoma
    • COI: 1:CAS:528:DC%2BC3sXhvFOmsrnE, PID: 24260081
    • Fu Y, Wei X, Tang C, Li J, Liu R, Shen A, et al. Circulating microRNA-101 as a potential biomarker for hepatitis B virus-related hepatocellular carcinoma. Oncol Lett. 2013;6(6):1811–5. doi:10.3892/ol.2013.1638.
    • (2013) Oncol Lett , vol.6 , Issue.6 , pp. 1811-1815
    • Fu, Y.1    Wei, X.2    Tang, C.3    Li, J.4    Liu, R.5    Shen, A.6
  • 23
    • 84903391546 scopus 로고    scopus 로고
    • Profiles of serum microRNAs; miR-125b-5p and miR223-3p serve as novel biomarkers for HBV-positive hepatocellular carcinoma
    • PID: 24595450
    • Giray BG, Emekdas G, Tezcan S, Ulger M, Serin MS, Sezgin O, et al. Profiles of serum microRNAs; miR-125b-5p and miR223-3p serve as novel biomarkers for HBV-positive hepatocellular carcinoma. Mol Biol Rep. 2014;. doi:10.1007/s11033-014-3322-3.
    • (2014) Mol Biol Rep
    • Giray, B.G.1    Emekdas, G.2    Tezcan, S.3    Ulger, M.4    Serin, M.S.5    Sezgin, O.6
  • 24
    • 79251638583 scopus 로고    scopus 로고
    • Serum microRNA characterization identifies miR-885-5p as a potential marker for detecting liver pathologies
    • COI: 1:CAS:528:DC%2BC3cXhsVGrsbzL, PID: 20815808
    • Gui J, Tian Y, Wen X, Zhang W, Zhang P, Gao J, et al. Serum microRNA characterization identifies miR-885-5p as a potential marker for detecting liver pathologies. Clin Sci Lond. 2011;120(5):183–93. doi:10.1042/cs20100297.
    • (2011) Clin Sci Lond , vol.120 , Issue.5 , pp. 183-193
    • Gui, J.1    Tian, Y.2    Wen, X.3    Zhang, W.4    Zhang, P.5    Gao, J.6
  • 25
    • 84885175599 scopus 로고    scopus 로고
    • Serum microRNA-1 and microRNA-122 are prognostic markers in patients with hepatocellular carcinoma
    • PID: 23810247
    • Koberle V, Kronenberger B, Pleli T, Trojan J, Imelmann E, Peveling-Oberhag J, et al. Serum microRNA-1 and microRNA-122 are prognostic markers in patients with hepatocellular carcinoma. Eur J Cancer. 2013;49(16):3442–9. doi:10.1016/j.ejca.2013.06.002.
    • (2013) Eur J Cancer , vol.49 , Issue.16 , pp. 3442-3449
    • Koberle, V.1    Kronenberger, B.2    Pleli, T.3    Trojan, J.4    Imelmann, E.5    Peveling-Oberhag, J.6
  • 26
    • 79952193037 scopus 로고    scopus 로고
    • Expression of serum miR-221 in human hepatocellular carcinoma and its prognostic significance
    • COI: 1:CAS:528:DC%2BC3MXjslChtL8%3D, PID: 21295551
    • Li J, Wang Y, Yu W, Chen J, Luo J. Expression of serum miR-221 in human hepatocellular carcinoma and its prognostic significance. Biochem Biophys Res Commun. 2011;406(1):70–3. doi:10.1016/j.bbrc.2011.01.111.
    • (2011) Biochem Biophys Res Commun , vol.406 , Issue.1 , pp. 70-73
    • Li, J.1    Wang, Y.2    Yu, W.3    Chen, J.4    Luo, J.5
  • 27
    • 84871610494 scopus 로고    scopus 로고
    • Serum miR-18a: a potential marker for hepatitis B virus-related hepatocellular carcinoma screening
    • COI: 1:CAS:528:DC%2BC38XhsFagsr%2FI, PID: 22865399
    • Li L, Guo Z, Wang J, Mao Y, Gao Q. Serum miR-18a: a potential marker for hepatitis B virus-related hepatocellular carcinoma screening. Dig Dis Sci. 2012;57(11):2910–6. doi:10.1007/s10620-012-2317-y.
    • (2012) Dig Dis Sci , vol.57 , Issue.11 , pp. 2910-2916
    • Li, L.1    Guo, Z.2    Wang, J.3    Mao, Y.4    Gao, Q.5
  • 28
    • 78649972032 scopus 로고    scopus 로고
    • Serum microRNA profiles serve as novel biomarkers for HBV infection and diagnosis of HBV-positive hepatocarcinoma
    • COI: 1:CAS:528:DC%2BC3cXhsFamurvJ, PID: 21098710
    • Li LM, Hu ZB, Zhou ZX, Chen X, Liu FY, Zhang JF, et al. Serum microRNA profiles serve as novel biomarkers for HBV infection and diagnosis of HBV-positive hepatocarcinoma. Cancer Res. 2010;70(23):9798–807. doi:10.1158/0008-5472.can-10-1001.
    • (2010) Cancer Res , vol.70 , Issue.23 , pp. 9798-9807
    • Li, L.M.1    Hu, Z.B.2    Zhou, Z.X.3    Chen, X.4    Liu, F.Y.5    Zhang, J.F.6
  • 29
    • 84860141964 scopus 로고    scopus 로고
    • Circulating miR-15b and miR-130b in serum as potential markers for detecting hepatocellular carcinoma: a retrospective cohort study
    • PID: 22403344
    • Liu AM, Yao TJ, Wang W, Wong KF, Lee NP, Fan ST, et al. Circulating miR-15b and miR-130b in serum as potential markers for detecting hepatocellular carcinoma: a retrospective cohort study. BMJ Open. 2012;2(2):e000825. doi:10.1136/bmjopen-2012-000825.
    • (2012) BMJ Open , vol.2 , Issue.2 , pp. 000825
    • Liu, A.M.1    Yao, T.J.2    Wang, W.3    Wong, K.F.4    Lee, N.P.5    Fan, S.T.6
  • 30
    • 82955217238 scopus 로고    scopus 로고
    • Serum microRNAs as biomarkers for hepatocellular carcinoma in Chinese patients with chronic hepatitis B virus infection
    • COI: 1:CAS:528:DC%2BC3MXhs1Oqur3M, PID: 22174818
    • Qi P, Cheng SQ, Wang H, Li N, Chen YF, Gao CF. Serum microRNAs as biomarkers for hepatocellular carcinoma in Chinese patients with chronic hepatitis B virus infection. PLoS One. 2011;6(12):e28486. doi:10.1371/journal.pone.0028486.
    • (2011) PLoS One , vol.6 , Issue.12 , pp. 28486
    • Qi, P.1    Cheng, S.Q.2    Wang, H.3    Li, N.4    Chen, Y.F.5    Gao, C.F.6
  • 31
    • 79952813995 scopus 로고    scopus 로고
    • Circulating microRNAs as biomarkers for hepatocellular carcinoma
    • COI: 1:CAS:528:DC%2BC3MXivFWhtL4%3D, PID: 21278583
    • Qu KZ, Zhang K, Li H, Afdhal NH, Albitar M. Circulating microRNAs as biomarkers for hepatocellular carcinoma. J Clin Gastroenterol. 2011;45(4):355–60. doi:10.1097/MCG.0b013e3181f18ac2.
    • (2011) J Clin Gastroenterol , vol.45 , Issue.4 , pp. 355-360
    • Qu, K.Z.1    Zhang, K.2    Li, H.3    Afdhal, N.H.4    Albitar, M.5
  • 32
    • 80055117557 scopus 로고    scopus 로고
    • Circulating microRNA-21 as a novel biomarker for hepatocellular carcinoma
    • COI: 1:CAS:528:DC%2BC3MXhs1GhsbjN, PID: 21749846
    • Tomimaru Y, Eguchi H, Nagano H, Wada H, Kobayashi S, Marubashi S, et al. Circulating microRNA-21 as a novel biomarker for hepatocellular carcinoma. J Hepatol. 2012;56(1):167–75. doi:10.1016/j.jhep.2011.04.026.
    • (2012) J Hepatol , vol.56 , Issue.1 , pp. 167-175
    • Tomimaru, Y.1    Eguchi, H.2    Nagano, H.3    Wada, H.4    Kobayashi, S.5    Marubashi, S.6
  • 33
    • 78651417662 scopus 로고    scopus 로고
    • Circulating microRNAs, miR-21, miR-122, and miR-223, in patients with hepatocellular carcinoma or chronic hepatitis
    • COI: 1:CAS:528:DC%2BC3MXksFKqtA%3D%3D, PID: 21229610
    • Xu J, Wu C, Che X, Wang L, Yu D, Zhang T, et al. Circulating microRNAs, miR-21, miR-122, and miR-223, in patients with hepatocellular carcinoma or chronic hepatitis. Mol Carcinog. 2011;50(2):136–42. doi:10.1002/mc.20712.
    • (2011) Mol Carcinog , vol.50 , Issue.2 , pp. 136-142
    • Xu, J.1    Wu, C.2    Che, X.3    Wang, L.4    Yu, D.5    Zhang, T.6
  • 34
    • 84875272279 scopus 로고    scopus 로고
    • Serum miR-483-5p as a potential biomarker to detect hepatocellular carcinoma
    • Zhang ZJ, Ge SX, Wang XM, Yuan Q, Yan Q, Ye HM, et al. Serum miR-483-5p as a potential biomarker to detect hepatocellular carcinoma. Hep Intl. 2013;7(1):199–207. doi:10.1007/s12072-012-9341-z.
    • (2013) Hep Intl , vol.7 , Issue.1 , pp. 199-207
    • Zhang, Z.J.1    Ge, S.X.2    Wang, X.M.3    Yuan, Q.4    Yan, Q.5    Ye, H.M.6
  • 35
    • 84876309932 scopus 로고    scopus 로고
    • Expression of miRNA-29b and its clinical significances in primary hepatic carcinoma
    • COI: 1:CAS:528:DC%2BC3sXht1OrsrjF, PID: 23863670
    • Zheng JJ, Yu FJ, Dong PH, Bai YH, Chen BC. Expression of miRNA-29b and its clinical significances in primary hepatic carcinoma. Zhonghua Yi Xue Za Zhi. 2013;93(12):888–91.
    • (2013) Zhonghua Yi Xue Za Zhi , vol.93 , Issue.12 , pp. 888-891
    • Zheng, J.J.1    Yu, F.J.2    Dong, P.H.3    Bai, Y.H.4    Chen, B.C.5
  • 36
    • 84555202717 scopus 로고    scopus 로고
    • Plasma microRNA panel to diagnose hepatitis B virus-related hepatocellular carcinoma
    • COI: 1:CAS:528:DC%2BC38Xhslygsrk%3D
    • Zhou J, Yu L, Gao X, Hu J, Wang J, Dai Z, et al. Plasma microRNA panel to diagnose hepatitis B virus-related hepatocellular carcinoma. J Clin Oncol Off J Am Soc Clin Oncol. 2011;29(36):4781–8. doi:10.1200/jco.2011.38.2697.
    • (2011) J Clin Oncol Off J Am Soc Clin Oncol , vol.29 , Issue.36 , pp. 4781-4788
    • Zhou, J.1    Yu, L.2    Gao, X.3    Hu, J.4    Wang, J.5    Dai, Z.6
  • 37
    • 84886422148 scopus 로고    scopus 로고
    • MicroRNAs as biomarkers for hepatocellular carcinoma: a diagnostic meta-analysis
    • PID: 24273935
    • Hu QY, Jiang H, Su J, Jia YQ. MicroRNAs as biomarkers for hepatocellular carcinoma: a diagnostic meta-analysis. Clin Lab. 2013;59(9–10):1113–20.
    • (2013) Clin Lab , vol.59 , Issue.9-10 , pp. 1113-1120
    • Hu, Q.Y.1    Jiang, H.2    Su, J.3    Jia, Y.Q.4
  • 38
    • 84919392465 scopus 로고    scopus 로고
    • Diagnostic value of circulating microRNAs for hepatocellular carcinoma
    • Yang Y, Zhu R. Diagnostic value of circulating microRNAs for hepatocellular carcinoma. Mol Biol Rep. 2014;. doi:10.1007/s11033-014-3578-7.
    • (2014) Mol Biol Rep
    • Yang, Y.1    Zhu, R.2
  • 39
    • 34547524771 scopus 로고    scopus 로고
    • MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer
    • COI: 1:CAS:528:DC%2BD2sXhtVWqsr3L, PID: 17681183
    • Meng F, Henson R, Wehbe-Janek H, Ghoshal K, Jacob ST, Patel T. MicroRNA-21 regulates expression of the PTEN tumor suppressor gene in human hepatocellular cancer. Gastroenterology. 2007;133(2):647–58. doi:10.1053/j.gastro.2007.05.022.
    • (2007) Gastroenterology , vol.133 , Issue.2 , pp. 647-658
    • Meng, F.1    Henson, R.2    Wehbe-Janek, H.3    Ghoshal, K.4    Jacob, S.T.5    Patel, T.6
  • 41
    • 84874964830 scopus 로고    scopus 로고
    • Circulating microRNA-92a and microRNA-21 as novel minimally invasive biomarkers for primary breast cancer
    • COI: 1:CAS:528:DC%2BC3sXhsVCgtLo%3D, PID: 23052693
    • Si H, Sun X, Chen Y, Cao Y, Chen S, Wang H, et al. Circulating microRNA-92a and microRNA-21 as novel minimally invasive biomarkers for primary breast cancer. J Cancer Res Clin Oncol. 2013;139(2):223–9. doi:10.1007/s00432-012-1315-y.
    • (2013) J Cancer Res Clin Oncol , vol.139 , Issue.2 , pp. 223-229
    • Si, H.1    Sun, X.2    Chen, Y.3    Cao, Y.4    Chen, S.5    Wang, H.6
  • 42
    • 79953178293 scopus 로고    scopus 로고
    • Plasma microRNAs as potential biomarkers for non-small-cell lung cancer
    • COI: 1:CAS:528:DC%2BC3MXjvFKgtLc%3D
    • Shen J, Todd NW, Zhang H, Yu L, Lingxiao X, Mei Y, et al. Plasma microRNAs as potential biomarkers for non-small-cell lung cancer. Lab Invest A J Tech Method Pathol. 2011;91(4):579–87. doi:10.1038/labinvest.2010.194.
    • (2011) Lab Invest A J Tech Method Pathol , vol.91 , Issue.4 , pp. 579-587
    • Shen, J.1    Todd, N.W.2    Zhang, H.3    Yu, L.4    Lingxiao, X.5    Mei, Y.6
  • 43
    • 79959298372 scopus 로고    scopus 로고
    • Identification of plasma microRNA-21 as a biomarker for early detection and chemosensitivity of non-small cell lung cancer
    • COI: 1:CAS:528:DC%2BC3MXhtVCktLjL, PID: 21627863
    • Wei J, Gao W, Zhu CJ, Liu YQ, Mei Z, Cheng T, et al. Identification of plasma microRNA-21 as a biomarker for early detection and chemosensitivity of non-small cell lung cancer. Chin J Cancer. 2011;30(6):407–14.
    • (2011) Chin J Cancer , vol.30 , Issue.6 , pp. 407-414
    • Wei, J.1    Gao, W.2    Zhu, C.J.3    Liu, Y.Q.4    Mei, Z.5    Cheng, T.6
  • 44
    • 84865503318 scopus 로고    scopus 로고
    • Plasma miR-21: a potential diagnostic marker of colorectal cancer
    • PID: 22868372
    • Kanaan Z, Rai SN, Eichenberger MR, Roberts H, Keskey B, Pan J, et al. Plasma miR-21: a potential diagnostic marker of colorectal cancer. Ann Surg. 2012;256(3):544–51. doi:10.1097/SLA.0b013e318265bd6f.
    • (2012) Ann Surg , vol.256 , Issue.3 , pp. 544-551
    • Kanaan, Z.1    Rai, S.N.2    Eichenberger, M.R.3    Roberts, H.4    Keskey, B.5    Pan, J.6
  • 45
    • 41749113108 scopus 로고    scopus 로고
    • MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer
    • COI: 1:CAS:528:DC%2BD1cXktFCnsrc%3D, PID: 17968323
    • Asangani IA, Rasheed SA, Nikolova DA, Leupold JH, Colburn NH, Post S, et al. MicroRNA-21 (miR-21) post-transcriptionally downregulates tumor suppressor Pdcd4 and stimulates invasion, intravasation and metastasis in colorectal cancer. Oncogene. 2008;27(15):2128–36. doi:10.1038/sj.onc.1210856.
    • (2008) Oncogene , vol.27 , Issue.15 , pp. 2128-2136
    • Asangani, I.A.1    Rasheed, S.A.2    Nikolova, D.A.3    Leupold, J.H.4    Colburn, N.H.5    Post, S.6
  • 46
    • 38149042783 scopus 로고    scopus 로고
    • Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells
    • COI: 1:CAS:528:DC%2BD1cXhsFaktw%3D%3D, PID: 17991735
    • Frankel LB, Christoffersen NR, Jacobsen A, Lindow M, Krogh A, Lund AH. Programmed cell death 4 (PDCD4) is an important functional target of the microRNA miR-21 in breast cancer cells. J Biol Chem. 2008;283(2):1026–33. doi:10.1074/jbc.M707224200.
    • (2008) J Biol Chem , vol.283 , Issue.2 , pp. 1026-1033
    • Frankel, L.B.1    Christoffersen, N.R.2    Jacobsen, A.3    Lindow, M.4    Krogh, A.5    Lund, A.H.6
  • 47
    • 34347266556 scopus 로고    scopus 로고
    • MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1)
    • COI: 1:CAS:528:DC%2BD2sXkvVynsLk%3D, PID: 17363372
    • Zhu S, Si ML, Wu H, Mo YY. MicroRNA-21 targets the tumor suppressor gene tropomyosin 1 (TPM1). J Biol Chem. 2007;282(19):14328–36. doi:10.1074/jbc.M611393200.
    • (2007) J Biol Chem , vol.282 , Issue.19 , pp. 14328-14336
    • Zhu, S.1    Si, M.L.2    Wu, H.3    Mo, Y.Y.4
  • 48
    • 84891157615 scopus 로고    scopus 로고
    • An integrative meta-analysis of microRNAs in hepatocellular carcinoma
    • COI: 1:CAS:528:DC%2BC2cXntlChtLY%3D
    • ElHefnawi M, Soliman B, Abu-Shahba N, Amer M. An integrative meta-analysis of microRNAs in hepatocellular carcinoma. Genom Proteom Bioinform. 2013;11(6):354–67. doi:10.1016/j.gpb.2013.05.007.
    • (2013) Genom Proteom Bioinform , vol.11 , Issue.6 , pp. 354-367
    • ElHefnawi, M.1    Soliman, B.2    Abu-Shahba, N.3    Amer, M.4
  • 49
    • 34247495591 scopus 로고    scopus 로고
    • miR-21-mediated tumor growth
    • COI: 1:CAS:528:DC%2BD2sXksF2rsb4%3D, PID: 17072344
    • Si ML, Zhu S, Wu H, Lu Z, Wu F, Mo YY. miR-21-mediated tumor growth. Oncogene. 2007;26(19):2799–803. doi:10.1038/sj.onc.1210083.
    • (2007) Oncogene , vol.26 , Issue.19 , pp. 2799-2803
    • Si, M.L.1    Zhu, S.2    Wu, H.3    Lu, Z.4    Wu, F.5    Mo, Y.Y.6
  • 50
    • 22244467087 scopus 로고    scopus 로고
    • MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells
    • COI: 1:CAS:528:DC%2BD2MXmt1eht7c%3D, PID: 16024602
    • Chan JA, Krichevsky AM, Kosik KS. MicroRNA-21 is an antiapoptotic factor in human glioblastoma cells. Cancer Res. 2005;65(14):6029–33. doi:10.1158/0008-5472.can-05-0137.
    • (2005) Cancer Res , vol.65 , Issue.14 , pp. 6029-6033
    • Chan, J.A.1    Krichevsky, A.M.2    Kosik, K.S.3
  • 51
    • 69549092445 scopus 로고    scopus 로고
    • MicroRNA-21 promotes cell proliferation and down-regulates the expression of programmed cell death 4 (PDCD4) in HeLa cervical carcinoma cells
    • COI: 1:CAS:528:DC%2BD1MXhtFSnsrzI, PID: 19682430
    • Yao Q, Xu H, Zhang QQ, Zhou H, Qu LH. MicroRNA-21 promotes cell proliferation and down-regulates the expression of programmed cell death 4 (PDCD4) in HeLa cervical carcinoma cells. Biochem Biophys Res Commun. 2009;388(3):539–42. doi:10.1016/j.bbrc.2009.08.044.
    • (2009) Biochem Biophys Res Commun , vol.388 , Issue.3 , pp. 539-542
    • Yao, Q.1    Xu, H.2    Zhang, Q.Q.3    Zhou, H.4    Qu, L.H.5
  • 52
    • 78649919224 scopus 로고    scopus 로고
    • MicroRNA-21 promotes the cell proliferation, invasion and migration abilities in ovarian epithelial carcinomas through inhibiting the expression of PTEN protein
    • COI: 1:CAS:528:DC%2BC3MXkt1en, PID: 21042775
    • Lou Y, Yang X, Wang F, Cui Z, Huang Y. MicroRNA-21 promotes the cell proliferation, invasion and migration abilities in ovarian epithelial carcinomas through inhibiting the expression of PTEN protein. Int J Mol Med. 2010;26(6):819–27.
    • (2010) Int J Mol Med , vol.26 , Issue.6 , pp. 819-827
    • Lou, Y.1    Yang, X.2    Wang, F.3    Cui, Z.4    Huang, Y.5
  • 53
    • 67349254469 scopus 로고    scopus 로고
    • MicroRNA-21 directly targets MARCKS and promotes apoptosis resistance and invasion in prostate cancer cells
    • COI: 1:CAS:528:DC%2BD1MXlsVKjtrw%3D, PID: 19302977
    • Li T, Li D, Sha J, Sun P, Huang Y. MicroRNA-21 directly targets MARCKS and promotes apoptosis resistance and invasion in prostate cancer cells. Biochem Biophys Res Commun. 2009;383(3):280–5. doi:10.1016/j.bbrc.2009.03.077.
    • (2009) Biochem Biophys Res Commun , vol.383 , Issue.3 , pp. 280-285
    • Li, T.1    Li, D.2    Sha, J.3    Sun, P.4    Huang, Y.5
  • 54
    • 79956207473 scopus 로고    scopus 로고
    • PDCD4 nuclear loss inversely correlates with miR-21 levels in colon carcinogenesis
    • COI: 1:CAS:528:DC%2BC3MXjsFylt7c%3D
    • Fassan M, Pizzi M, Giacomelli L, Mescoli C, Ludwig K, Pucciarelli S, et al. PDCD4 nuclear loss inversely correlates with miR-21 levels in colon carcinogenesis. Virchows Archiv An Int J Pathol. 2011;458(4):413–9. doi:10.1007/s00428-011-1046-5.
    • (2011) Virchows Archiv An Int J Pathol , vol.458 , Issue.4 , pp. 413-419
    • Fassan, M.1    Pizzi, M.2    Giacomelli, L.3    Mescoli, C.4    Ludwig, K.5    Pucciarelli, S.6
  • 55
    • 70350214454 scopus 로고    scopus 로고
    • microRNA-21 negatively regulates Cdc25A and cell cycle progression in colon cancer cells
    • COI: 1:CAS:528:DC%2BD1MXht1ynu77L, PID: 19826040
    • Wang P, Zou F, Zhang X, Li H, Dulak A, Tomko RJ Jr, et al. microRNA-21 negatively regulates Cdc25A and cell cycle progression in colon cancer cells. Cancer Res. 2009;69(20):8157–65. doi:10.1158/0008-5472.can-09-1996.
    • (2009) Cancer Res , vol.69 , Issue.20 , pp. 8157-8165
    • Wang, P.1    Zou, F.2    Zhang, X.3    Li, H.4    Dulak, A.5    Tomko, R.J.6
  • 56
    • 79953202200 scopus 로고    scopus 로고
    • Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma
    • COI: 1:CAS:528:DC%2BC3MXktVCjsro%3D, PID: 21383194
    • Arroyo JD, Chevillet JR, Kroh EM, Ruf IK, Pritchard CC, Gibson DF, et al. Argonaute2 complexes carry a population of circulating microRNAs independent of vesicles in human plasma. Proc Natl Acad Sci USA. 2011;108(12):5003–8. doi:10.1073/pnas.1019055108.
    • (2011) Proc Natl Acad Sci USA , vol.108 , Issue.12 , pp. 5003-5008
    • Arroyo, J.D.1    Chevillet, J.R.2    Kroh, E.M.3    Ruf, I.K.4    Pritchard, C.C.5    Gibson, D.F.6
  • 57
    • 79953301730 scopus 로고    scopus 로고
    • MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins
    • COI: 1:CAS:528:DC%2BC3MXktFWjsb4%3D, PID: 21423178
    • Vickers KC, Palmisano BT, Shoucri BM, Shamburek RD, Remaley AT. MicroRNAs are transported in plasma and delivered to recipient cells by high-density lipoproteins. Nat Cell Biol. 2011;13(4):423–33. doi:10.1038/ncb2210.
    • (2011) Nat Cell Biol , vol.13 , Issue.4 , pp. 423-433
    • Vickers, K.C.1    Palmisano, B.T.2    Shoucri, B.M.3    Shamburek, R.D.4    Remaley, A.T.5
  • 58
    • 79957784825 scopus 로고    scopus 로고
    • Analysis of circulating microRNA: preanalytical and analytical challenges
    • COI: 1:CAS:528:DC%2BC3MXnvVKjs7s%3D, PID: 21487102
    • McDonald JS, Milosevic D, Reddi HV, Grebe SK, Algeciras-Schimnich A. Analysis of circulating microRNA: preanalytical and analytical challenges. Clin Chem. 2011;57(6):833–40. doi:10.1373/clinchem.2010.157198.
    • (2011) Clin Chem , vol.57 , Issue.6 , pp. 833-840
    • McDonald, J.S.1    Milosevic, D.2    Reddi, H.V.3    Grebe, S.K.4    Algeciras-Schimnich, A.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.