Histological patterns in healing chronic wounds using Cochliomyia macellaria (Diptera: Calliphoridae) larvae and other therapeutic measures

Parasitology Research

Volumn 114, Issue 8, 2015, Pages 2865-2872

  de Masiero, Franciéle Souza ^a   Nassu, Mariana Prado ^b   Soares, Mauro Pereira ^a   Thyssen, Patricia Jacqueline ^b  

^a FEDERAL UNIVERSITY OF PELOTAS   (Brazil)

^b UNIVERSITY OF CAMPINAS   (Brazil)

Author keywords

Blowflies; Larval therapy; Lesions; Wound dressing

Indexed keywords

HISTIDINE; SILVER; ANTIINFECTIVE AGENT;

ADULT; ALTERNATIVE MEDICINE; ANGIOGENESIS; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTIBACTERIAL ACTIVITY; ARTICLE; BACTERIAL COLONIZATION; BACTERIAL GROWTH; BLOOD VESSEL PERMEABILITY; CHRONIC WOUND; COCHLIOMYIA; COCHLIOMYIA MACELLARIA; CONTROLLED STUDY; DEBRIDEMENT; ENDOTHELIUM CELL; FEMALE; FOAM DRESSING; HEALTH CARE COST; HISTOPATHOLOGY; INFLAMMATION; INFLAMMATORY INFILTRATE; INNATE IMMUNITY; LARVA; MACROPHAGE; MAGGOT THERAPY; MALE; NEUTROPHIL; NEUTROPHIL CHEMOTAXIS; NONHUMAN; PRIORITY JOURNAL; RAT; TISSUE REPAIR; WOUND HEALING; ANIMAL; DIPTERA; HUMAN; PHYSIOLOGY; WISTAR RAT;

ANIMALIA; BACTERIA (MICROORGANISMS); CALLIPHORIDAE; COCHLIOMYIA MACELLARIA; DIPTERA; RATTUS NORVEGICUS;

ANIMALS; ANTI-BACTERIAL AGENTS; DIPTERA; HUMANS; LARVA; MALE; RATS; RATS, WISTAR; WOUND HEALING;

EID: 84938967533     PISSN: 09320113     EISSN: 14321955     Source Type: Journal    
DOI: 10.1007/s00436-015-4487-y     Document Type: Article

References (37)

1. Abu Al-Basal MA (2010) Healing potential of Rosmarinus officinalis L. on full-thickness excision cutaneous wounds in alloxan-induced-diabetic BALB/c mice. J Ethnopharmacol 131:443–450
2. Bexfield A, Bond AE, Morgan C, Wagstaff J, Newton RP, Ratcliffe NA, Dudley E, Nigam Y (2009) Amino acid derivatives from Lucilia sericata excretions⁄secretions may contribute to the beneficial effects of maggot therapy via increased angiogenesis. Br J Dermatol 162:554–562
3. Campos ACL, Borges-Branco A, Groth AK (2007) Cicatrização de feridas. ABCD Arq Bras Cir Dig 20:51–58
4. Cazander G, Veerdonk V, Vandenbroucke-Grauls C, Schreurs MW, Jukema GN (2010) Maggot excretions inhibit biofilm formation on biomaterials. Clin Orthop Relat Res 468:2789–2796
5. Chambers L, Woodrow S, Brown A (2003) Degradation of extracellular matrix components by defined proteinases from the greenbottle larva: Lucilia sericata used for the clinical debridement of non-healing wounds. Br J Dermatol 148:14–23
6. El-Tantawy NL (2015) Helminthes and insects: maladies or therapies. Parasitol Res 114:359–377
7. Erdmann GR, Khalil SK (1986) Isolation and identification of two antibacterial agents produced by a strain of Proteus mirabilis isolated from larvae of the screwworm (Cochliomyia hominivorax) (Diptera: Calliphoridae). J Med Entomol 23:208–211
8. Feldmeier H, Witt L, Schwalfenberg S, Ribeiro RA, Cunha FQ, Harms G, Mehlhorn H, Liesenfeld O, Heukelbach J (2004) Investigations on the biology, epidemiology, pathology and control of Tunga penetrans in Brazil. V. Cytokine concentrations in experimentally infected Wistar rats. Parasitol Res 94:371–376
9. Fleishmann W, Grassberger M, Sherman R (2004) Maggot therapy: a handbook of maggot assisted wound healing. Thieme, Stuttgart
10. Francesconi F, Lupi O (2012) Myiasis. Clin Microbiol Rev 25:70–205
11. Gantwerker EA, Hom DB (2012) Skin: histology and physiology of wound healing. Clin Plast Surg 39:85–97
12. Gorti GK, Ronson S, Koch RJ (2002) Wound healing. Facial Plast Surg Clin N Am 10:119–127
13. Grella MD, Thyssen PJ (2011) Chave taxonômica interativa para espécies de dípteros califorídeos (Infraordem: Muscomorpha) do Brasil. http://keys.lucidcentral.org/keys/v3/calliphoridae_brazil. Accessed 09 January 2015
14. Marcondes CB (2006) Terapia larval: de lesões de Pele causadas por diabetes e outras doenças. Editora da UFSC, Santa Catarina, 89p
15. Martin CW, Muir FK (1990) The role of lymphocytes in wound healing. Br J PIast Surg 43:655–662
16. Mehlhorn H, Al-Rasheid KAS, Al-Quraishy S, Abdel-Ghaffar F (2012) Research and increase of expertise in arachno-entomology are urgently needed. Parasitol Res 110:259–265
17. Mendonça RJ, Coutinho-Netto J (2009) Aspectos celulares da cicatrização. An Bras Dermatol 84:257–262
18. Moretti TC, Thyssen PJ, Solis DR (2009) Breeding of the scuttle Fly Megaselia scalaris in a fish carcass and implications for the use in forensic entomology (Diptera: Phoridae). Entomol Gen 31:349–353
19. Nitsche, MJT (2010) Avaliação da recuperação de lesões cutâneas por meio de terapia larval utilizando como modelos ratos Wistar. Dissertation, Universidade Estadual Paulista
20. Prazeres SJ (2009) Tratamento de feridas: teoria e prática. Moriá, Porto Alegre
21. Prete PE (1997) Growth effects of Phaenicia sericata larval extracts on fibroblasts: mechanism for wound healing by maggot therapy. Life Sci 60:505–510
22. Schreml S, Szeimies RM, Prantl L, Landthaler M, Babilas P (2010) Wound healing in the 21st century. J Am Acad Dermatol 63:866–881
23. Sherman RA (2009) Maggot therapy takes us back to the future of wound care: new and improved maggot therapy for the 21st century. J Diabetes Sci Technol 3:336–344
24. Sherman RA, Hall MJ, Thomas S (2000) Medicinal maggots: an ancient remedy for some contemporary afflictions. Ann Rev Entomol 45:55–81
25. Singer AJ, Clark RA (1999) Cutaneous wound healing. N Engl J Med 341:738–746
26. Singh B, Sharma S, Dhiman A (2013) Design of antibiotic containing hydrogel wound dressings: biomedical properties and histological study of wound healing. Int J Pharm 457:82–91
27. Strodtbeck F (2001) Physiology of wound healing. Newborn Infant Nurs Rev 1:43–52
28. Téllez GA, Acero MA, Pineda LA, Castaño JC (2012) Larvaterapia aplicada a heridas con poca carga de tejido necrótico y caracterización enzimática de la excreción, secreción y hemolinfa de larvas. Biomedica 32:312–320
29. Thyssen PJ, Nassu MP, Nitsche MJT, Leite D (2013) Sterilization of immature blowflies (Calliphoridae) for use in larval therapy. J Med Sci 4:405–409
30. Tsirogianni AK, Moutsopoulos NM, Moutsopoulos HM (2006) Wound healing: immunological aspects. Int J Care Injured 37:5–12
31. Valachová I, Bohová J, Pálošová Z, Takáč P, Kozánek M, Majtán J (2013) Expression of lucifensin in Lucilia sericata medicinal maggots in infected environments. Cell Tissue Res 353:165–171
32. Van Der Plas M, Van Der Does A, Baldry M, Dogterom-Ballering H, Gulpen C, Van Dissel J, Nibbering P, Jukema G (2007) Maggot excretions/secretions inhibit multiple neutrophilpro-inflammatory responses. Microbes Infect 9:507–514
33. Van der Plas MJA, Dissel JTV, Nibbering PH (2009) Maggot secretions skew monocyte-macrophage differentiation away from a pro-inflammatory to a pro-angiogenic type. PLoS ONE 4:1–10
34. Wang S, Wang K, Xin Y, Lv D (2010) Maggot excretions/secretions induces human microvascular endothelial cell migration through AKT1. Mol Biol Rep 37:2719–2725
35. West J (1998) Wound healing. In: Patrick CW Jr, Mikos AG, Mcintire LV (eds) Frontiers in tissue engineering, 1st edn. Elsevier Science, Oxford, pp 138–151
36. Witte MB, Barbul A (1997) General principles of wound healing. Surg Clin N Am 77:509–528
37. Zhang Z, Wang S, Diao Y, Zhang J, Lv D (2010) Fatty acid extracts from Lucilia sericata larvae promote murine cutaneous wound healing by angiogenic activity. Lipids Health Dis 9:1–9