In Vivo Imaging of the Cannabinoid CB1 Receptor with Positron Emission Tomography

Clinical Pharmacology and Therapeutics

Volumn 97, Issue 6, 2015, Pages 565-567

  Hirvonen, J ^a  

^a TURKU UNIVERSITY HOSPITAL   (Finland)

Author keywords

[No Author keywords available]

Indexed keywords

CANNABINOID 1 RECEPTOR; 2 PYRROLIDONE DERIVATIVE; 5-((3-FLUOROMETHOXY)PHENYL)-3-(1-PHENYLETHYLAMINO)-1-(4-TRIFLUOROMETHYLPHENYL)PYRROLIDIN-2-ONE;

ADDICTION; ALCOHOLISM; ARTICLE; CANNABIS ADDICTION; HUMAN; IN VIVO STUDY; NEUROIMAGING; NONHUMAN; POSITRON EMISSION TOMOGRAPHY; PRIORITY JOURNAL; RECEPTOR AFFINITY; RECEPTOR BINDING; RECEPTOR DOWN REGULATION; SINGLE NUCLEOTIDE POLYMORPHISM; SPATIOTEMPORAL ANALYSIS; ANIMAL; DIAGNOSTIC USE; METABOLISM; PROCEDURES;

ALCOHOLISM; ANIMALS; HUMANS; POSITRON-EMISSION TOMOGRAPHY; PYRROLIDINONES; RECEPTOR, CANNABINOID, CB1;

EID: 84938948025     PISSN: 00099236     EISSN: 15326535     Source Type: Journal    
DOI: 10.1002/cpt.116     Document Type: Article

References (5)

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3. Terry, G.E. et al. Imaging and quantitation of cannabinoid CB1 receptors in human and monkey brains using (18)F-labeled inverse agonist radioligands. J. Nucl. Med. 51, 112-120 (2010).
4. Hirvonen, J. et al. Reversible and regionally selective downregulation of brain cannabinoid CB1 receptors in chronic daily cannabis smokers. Mol. Psychiatry 17, 642-649 (2012).
5. Hirvonen, J. et al. Reduced cannabinoid CB1 receptor binding in alcohol dependence measured with positron emission tomography. Mol. Psychiatry 18, 916-921 (2013).