-
1
-
-
40849094167
-
Human cutaneous melanoma; a review of NRAS and BRAF mutation frequencies in relation to histogenetic subclass and body site
-
Platz A et al (2008) Human cutaneous melanoma; a review of NRAS and BRAF mutation frequencies in relation to histogenetic subclass and body site Mol Oncol 1 395-405 DOI: 10.1016/j.molonc.2007.12.003
-
(2008)
Mol Oncol
, vol.1
, pp. 395-405
-
-
Platz, A.1
-
2
-
-
84896090174
-
Dragging ras back in the ring
-
Stephen AG et al (2012) Dragging ras back in the ring Cancer Cell 25 272-281 DOI: 10.1016/j.ccr.2014.02.017
-
(2012)
Cancer Cell
, vol.25
, pp. 272-281
-
-
Stephen, A.G.1
-
3
-
-
84861147473
-
A comprehensive survey of Ras mutations in cancer
-
PMID: 22589270 PMCID: 3354961
-
Prior IA, Lewis PD and Mattos C (2012) A comprehensive survey of Ras mutations in cancer Cancer Res 72 2457-2467 DOI: 10.1158/0008-5472.CAN-11-2612 PMID: 22589270 PMCID: 3354961
-
(2012)
Cancer Res
, vol.72
, pp. 2457-2467
-
-
Prior, I.A.1
Lewis, P.D.2
Mattos, C.3
-
4
-
-
84883347910
-
Mutation incidence and coincidence in nonsmall-cell lung cancer: Meta-analyses by ethnicity and histology (mutMap)
-
PMID: 23723294 PMCID: 3755331
-
Dearden S et al (2013) Mutation incidence and coincidence in nonsmall-cell lung cancer: meta-analyses by ethnicity and histology (mutMap) Ann Oncol 24 2371-2376 DOI: 10.1093/annonc/mdt205 PMID: 23723294 PMCID: 3755331
-
(2013)
Ann Oncol
, vol.24
, pp. 2371-2376
-
-
Dearden, S.1
-
5
-
-
84862294110
-
Optimization of patient selection for EGFR-TKIs in advanced non-small cell lung cancer by combined analysis of KRAS, PIK3CA, MET, and non-sensitizing EGFR mutations
-
PMID: 22302407
-
Ludovini V et al (2012) Optimization of patient selection for EGFR-TKIs in advanced non-small cell lung cancer by combined analysis of KRAS, PIK3CA, MET, and non-sensitizing EGFR mutations Cancer Chemother Pharmacol 69 1289-1299 DOI: 10.1007/s00280-012-1829-7 PMID: 22302407
-
(2012)
Cancer Chemother Pharmacol
, vol.69
, pp. 1289-1299
-
-
Ludovini, V.1
-
6
-
-
76949093606
-
Activating K-Ras mutations outwith 'hotspot' codons in sporadic colorectal tumours - Implications for personalised cancer medicine
-
PMID: 20147967 PMCID: 2837563
-
Smith G et al (2010) Activating K-Ras mutations outwith 'hotspot' codons in sporadic colorectal tumours - implications for personalised cancer medicine Br J Cancer 102 693-703 DOI: 10.1038/sj.bjc.6605534 PMID: 20147967 PMCID: 2837563
-
(2010)
Br J Cancer
, vol.102
, pp. 693-703
-
-
Smith, G.1
-
7
-
-
84878862323
-
Amplification of the MET receptor drives resistance to anti-EGFR therapies in colorectal cancer
-
PMID: 23729478 PMCID: 4078408
-
Bardelli A et al (2013) Amplification of the MET receptor drives resistance to anti-EGFR therapies in colorectal cancer Cancer Discov 3 658-673 DOI: 10.1158/2159-8290.CD-12-0558 PMID: 23729478 PMCID: 4078408
-
(2013)
Cancer Discov
, vol.3
, pp. 658-673
-
-
Bardelli, A.1
-
9
-
-
0034735995
-
A novel activating mutation of the K-ras gene in human primary colon adenocarcinoma
-
PMID: 11095964
-
Tsukuda K et al (2000) A novel activating mutation of the K-ras gene in human primary colon adenocarcinoma Biochem Biophys Res Commun 278 653-658 DOI: 10.1006/bbrc.2000.3839 PMID: 11095964
-
(2000)
Biochem Biophys Res Commun
, vol.278
, pp. 653-658
-
-
Tsukuda, K.1
-
10
-
-
77955046517
-
Genomic and biological characterization of exon 4 KRAS mutations in human cancer
-
PMID: 20570890 PMCID: 2943514
-
Janakiraman M et al (2010) Genomic and biological characterization of exon 4 KRAS mutations in human cancer Cancer Res 70 5901-5911 DOI: 10.1158/0008-5472.CAN-10-0192 PMID: 20570890 PMCID: 2943514
-
(2010)
Cancer Res
, vol.70
, pp. 5901-5911
-
-
Janakiraman, M.1
-
11
-
-
84878981521
-
Prognostic value of K-RAS mutations in patients with non-small cell lung cancer: A systematic review with meta-analysis
-
PMID: 23608713
-
Meng D et al (2013) Prognostic value of K-RAS mutations in patients with non-small cell lung cancer: a systematic review with meta-analysis Lung Cancer 81 1-10 DOI: 10.1016/j.lungcan.2013.03.019 PMID: 23608713
-
(2013)
Lung Cancer
, vol.81
, pp. 1-10
-
-
Meng, D.1
-
12
-
-
84891827722
-
Clinical outcome with platinum-based chemotherapy in patients with advanced nonsquamous EGFR wild-type non-small-cell lung cancer segregated according to KRAS mutation status
-
Metro G et al (2014) Clinical outcome with platinum-based chemotherapy in patients with advanced nonsquamous EGFR wild-type non-small-cell lung cancer segregated according to KRAS mutation status Clin Lung Cancer 15 86-92 DOI: 10.1016/j.cllc.2013.08.002
-
(2014)
Clin Lung Cancer
, vol.15
, pp. 86-92
-
-
Metro, G.1
-
13
-
-
77955096407
-
KRAS mutations and resistance to EGFR-TKIs treatment in patients with non-small cell lung cancer: A meta-analysis of 22 studies
-
Mao C et al (2010) KRAS mutations and resistance to EGFR-TKIs treatment in patients with non-small cell lung cancer: a meta-analysis of 22 studies Lung Cancer 69 272-278 DOI: 10.1016/j.lungcan.2009.11.020
-
(2010)
Lung Cancer
, vol.69
, pp. 272-278
-
-
Mao, C.1
-
14
-
-
84866147012
-
Impact of specific mutant KRAS on clinical outcome of EGFR-TKI-treated advanced non-small cell lung cancer patients with an EGFR wild type genotype
-
PMID: 22770374
-
Metro G et al (2012) Impact of specific mutant KRAS on clinical outcome of EGFR-TKI-treated advanced non-small cell lung cancer patients with an EGFR wild type genotype Lung Cancer 78 81-86 DOI: 10.1016/j.lungcan.2012.06.005 PMID: 22770374
-
(2012)
Lung Cancer
, vol.78
, pp. 81-86
-
-
Metro, G.1
-
15
-
-
78651109803
-
Evaluation of Kras gene mutation and copy number gain in non-small cell lung cancer
-
Sasaki H et al (2011) Evaluation of Kras gene mutation and copy number gain in non-small cell lung cancer J Thorac Oncol 6 15-20 DOI: 10.1097/JTO.0b013e31820594f0
-
(2011)
J Thorac Oncol
, vol.6
, pp. 15-20
-
-
Sasaki, H.1
-
16
-
-
82555194053
-
KRAS mutant allele-specific imbalance in lung adenocarcinoma
-
Chiosea SI et al (2012) KRAS mutant allele-specific imbalance in lung adenocarcinoma Mod Pathol 24 1571-1577 DOI: 10.1038/modpathol.2011.109
-
(2012)
Mod Pathol
, vol.24
, pp. 1571-1577
-
-
Chiosea, S.I.1
-
17
-
-
84871720411
-
Selumetinib plus docetaxel for KRAS-mutant advanced non-small-cell lung cancer: A randomised, multicentre, placebo-controlled, phase 2 study
-
Jänne PA et al (2013) Selumetinib plus docetaxel for KRAS-mutant advanced non-small-cell lung cancer: a randomised, multicentre, placebo-controlled, phase 2 study Lancet Oncol 14 38-47 DOI: 10.1016/S1470-2045(12)70489-8
-
(2013)
Lancet Oncol
, vol.14
, pp. 38-47
-
-
Jänne, P.A.1
-
18
-
-
84894491192
-
MEK114653: A randomized, multicenter, phase II study to assess efficacy and safety of trametinib (T) compared with docetaxel (D) in KRAS-mutant advanced non-small cell lung cancer (NSCLC)
-
Blumenschein GR et al (2013) MEK114653: a randomized, multicenter, phase II study to assess efficacy and safety of trametinib (T) compared with docetaxel (D) in KRAS-mutant advanced non-small cell lung cancer (NSCLC) J Clin Oncol 31(suppl) abstract 8029
-
(2013)
J Clin Oncol
, vol.31
-
-
Blumenschein, G.R.1
|