Ergosterol peroxide from Chaga mushroom (Inonotus obliquus) exhibits anti-cancer activity by down-regulation of the β-catenin pathway in colorectal cancer

Journal of Ethnopharmacology

Volumn 173, Issue , 2015, Pages 303-312

  Kang, Ju Hee ^a,b,f   Jang, Jeong Eun ^a   Mishra, Siddhartha Kumar ^c   Lee, Hee Ju ^d   Nho, Chu Won ^d   Shin, Dongyun ^a   Jin, Mirim ^e   Kim, Mi Kyung ^b   Choi, Changsun ^f   Oh, Seung Hyun ^a  

^a Gachon University   (South Korea)

^b National Cancer Center   (South Korea)

^c DR H S GOUR UNIVERSITY   (India)

^d Korea Institute of Science and Technology   (South Korea)

^e Daejeon University   (South Korea)

^f Chung Ang University   (South Korea)

Author keywords

AOM DSS; Chaga mushroom; Colorectal cancer; Ergosterol peroxide; catenin

Indexed keywords

AZOXYMETHANE; BETA CATENIN; CYCLIN D1; CYCLIN DEPENDENT KINASE 8; DEXTRAN SULFATE; ERGOSTEROL PEROXIDE; INONOTUS OBLIQUUS EXTRACT; KI 67 ANTIGEN; MESSENGER RNA; MYC PROTEIN; UNCLASSIFIED DRUG; ANTINEOPLASTIC AGENT; ERGOSTEROL; ERGOSTEROL-5,8-PEROXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANTINEOPLASTIC ACTIVITY; ANTIPROLIFERATIVE ACTIVITY; APOPTOSIS; ARTICLE; CANCER INHIBITION; CELL PROLIFERATION; CELL VIABILITY; CLONOGENESIS; COLITIS; COLON ADENOCARCINOMA; COLONY FORMATION; COLORECTAL CANCER; CONTROLLED STUDY; DOWN REGULATION; DRUG INHIBITION; DRUG MECHANISM; FEMALE; FLOW CYTOMETRY; FLUORESCENCE ACTIVATED CELL SORTING; HCT116 CELL LINE; HT 29 CELL LINE; HUMAN; HUMAN CELL; IMMUNOHISTOCHEMISTRY; INONOTUS OBLIQUUS; MOUSE; MTT ASSAY; NONHUMAN; NUCLEAR MAGNETIC RESONANCE; REVERSE TRANSCRIPTION POLYMERASE CHAIN REACTION; TUNEL ASSAY; WESTERN BLOTTING; ADENOCARCINOMA; AGARICALES; ANALOGS AND DERIVATIVES; ANIMAL; C57BL MOUSE; CELL SURVIVAL; COLON; COLORECTAL NEOPLASMS; COMPLICATION; DRUG EFFECTS; GENETICS; METABOLISM; PATHOLOGY; SIGNAL TRANSDUCTION; TUMOR CELL LINE;

BASIDIOMYCOTA; INONOTUS OBLIQUUS; MUS;

ADENOCARCINOMA; AGARICALES; ANIMALS; ANTINEOPLASTIC AGENTS; APOPTOSIS; BETA CATENIN; CELL LINE, TUMOR; CELL PROLIFERATION; CELL SURVIVAL; COLITIS; COLON; COLORECTAL NEOPLASMS; DOWN-REGULATION; ERGOSTEROL; FEMALE; HUMANS; MICE, INBRED C57BL; SIGNAL TRANSDUCTION;

EID: 84938894781     PISSN: 03788741     EISSN: 18727573     Source Type: Journal    
DOI: 10.1016/j.jep.2015.07.030     Document Type: Article

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