메뉴 건너뛰기




Volumn 33, Issue 8, 2015, Pages 1079-1085

Androgen deprivation therapy in castrate-resistant prostate cancer: how important is GnRH agonist backbone therapy?

Author keywords

Backbone androgen deprivation therapy; Castrate resistant prostate cancer; Individualised management

Indexed keywords

ABIRATERONE; ANDROSTANE DERIVATIVE; ANTINEOPLASTIC AGENT; ANTINEOPLASTIC HORMONE AGONISTS AND ANTAGONISTS; CABAZITAXEL; ENZALUTAMIDE; GONADORELIN; LEUPRORELIN; PHENYLTHIOHYDANTOIN; RADIOISOTOPE; RADIUM; RADIUM CHLORIDE RA 223; SIPULEUCEL T; TAXOID; TISSUE EXTRACT;

EID: 84938892863     PISSN: 07244983     EISSN: 14338726     Source Type: Journal    
DOI: 10.1007/s00345-014-1406-2     Document Type: Review
Times cited : (34)

References (45)
  • 1
    • 84891809097 scopus 로고    scopus 로고
    • EAU guidelines on prostate cancer. Part II: treatment of advanced, relapsing, and castration-resistant prostate cancer
    • COI: 1:CAS:528:DC%2BC3sXitVWju77J, PID: 24321502
    • Heidenreich A, Bastian PJ, Bellmunt J et al (2014) EAU guidelines on prostate cancer. Part II: treatment of advanced, relapsing, and castration-resistant prostate cancer. Eur Urol 65(2):467–479
    • (2014) Eur Urol , vol.65 , Issue.2 , pp. 467-479
    • Heidenreich, A.1    Bastian, P.J.2    Bellmunt, J.3
  • 2
    • 84938891503 scopus 로고    scopus 로고
    • Castration-resistant prostate cancer, AUA guideline
    • Cookson MS, Roth BJ, Dahm P et al (2013) Castration-resistant prostate cancer: AUA guideline
    • (2013) Dahm P et al
    • Cookson, M.S.1    Roth, B.J.2
  • 3
    • 84902445828 scopus 로고    scopus 로고
    • NCCN clinical practice guidelines in oncology
    • NCCN (2014) NCCN clinical practice guidelines in oncology. Prostate Cancer
    • (2014) Prostate Cancer
  • 4
    • 84866948935 scopus 로고    scopus 로고
    • Abiraterone acetate for treatment of metastatic castration-resistant prostate cancer: final overall survival analysis of the COU-AA-301 randomised, double-blind, placebo-controlled phase 3 study
    • COI: 1:CAS:528:DC%2BC38XhsVCjsbjK, PID: 22995653
    • Fizazi K, Scher HI, Molina A et al (2012) Abiraterone acetate for treatment of metastatic castration-resistant prostate cancer: final overall survival analysis of the COU-AA-301 randomised, double-blind, placebo-controlled phase 3 study. Lancet Oncol 13(10):983–992
    • (2012) Lancet Oncol , vol.13 , Issue.10 , pp. 983-992
    • Fizazi, K.1    Scher, H.I.2    Molina, A.3
  • 5
    • 84872078210 scopus 로고    scopus 로고
    • Abiraterone in metastatic prostate cancer without previous chemotherapy
    • COI: 1:CAS:528:DC%2BC3sXovVyhtw%3D%3D, PID: 23228172
    • Ryan CJ, Smith MR, de Bono JS et al (2013) Abiraterone in metastatic prostate cancer without previous chemotherapy. N Engl J Med 368(2):138–148
    • (2013) N Engl J Med , vol.368 , Issue.2 , pp. 138-148
    • Ryan, C.J.1    Smith, M.R.2    de Bono, J.S.3
  • 6
    • 84866770294 scopus 로고    scopus 로고
    • Increased survival with enzalutamide in prostate cancer after chemotherapy
    • COI: 1:CAS:528:DC%2BC38XhsVKhsLvK, PID: 22894553
    • Scher HI, Fizazi K, Saad F et al (2012) Increased survival with enzalutamide in prostate cancer after chemotherapy. N Engl J Med 367(13):1187–1197
    • (2012) N Engl J Med , vol.367 , Issue.13 , pp. 1187-1197
    • Scher, H.I.1    Fizazi, K.2    Saad, F.3
  • 7
    • 84908450155 scopus 로고    scopus 로고
    • Enzalutamide in metastatic prostate cancer before chemotherapy
    • PID: 24881730
    • Beer TM, Armstrong AJ, Rathkopf DE et al (2014) Enzalutamide in metastatic prostate cancer before chemotherapy. N Engl J Med 371(5):424–433
    • (2014) N Engl J Med , vol.371 , Issue.5 , pp. 424-433
    • Beer, T.M.1    Armstrong, A.J.2    Rathkopf, D.E.3
  • 8
    • 77955066199 scopus 로고    scopus 로고
    • Sipuleucel-T immunotherapy for castration-resistant prostate cancer
    • COI: 1:CAS:528:DC%2BC3cXhtVGlurrN, PID: 20818862
    • Kantoff PW, Higano CS, Shore ND et al (2010) Sipuleucel-T immunotherapy for castration-resistant prostate cancer. N Engl J Med 363(5):411–422
    • (2010) N Engl J Med , vol.363 , Issue.5 , pp. 411-422
    • Kantoff, P.W.1    Higano, C.S.2    Shore, N.D.3
  • 9
    • 84880428467 scopus 로고    scopus 로고
    • Alpha emitter radium-223 and survival in metastatic prostate cancer
    • COI: 1:CAS:528:DC%2BC3sXhtFKls77M, PID: 23863050
    • Parker C, Nilsson S, Heinrich D et al (2013) Alpha emitter radium-223 and survival in metastatic prostate cancer. N Engl J Med 369(3):213–223
    • (2013) N Engl J Med , vol.369 , Issue.3 , pp. 213-223
    • Parker, C.1    Nilsson, S.2    Heinrich, D.3
  • 10
    • 77957682309 scopus 로고    scopus 로고
    • Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: a randomised open-label trial
    • PID: 20888992
    • de Bono JS, Oudard S, Ozguroglu M et al (2010) Prednisone plus cabazitaxel or mitoxantrone for metastatic castration-resistant prostate cancer progressing after docetaxel treatment: a randomised open-label trial. Lancet 376(9747):1147–1154
    • (2010) Lancet , vol.376 , Issue.9747 , pp. 1147-1154
    • de Bono, J.S.1    Oudard, S.2    Ozguroglu, M.3
  • 11
    • 34548400276 scopus 로고    scopus 로고
    • Redefining clinically significant castration levels in patients with prostate cancer receiving continuous androgen deprivation therapy
    • COI: 1:CAS:528:DC%2BD2sXhtFKnsbrJ, PID: 17698136
    • Morote J, Orsola A, Planas J et al (2007) Redefining clinically significant castration levels in patients with prostate cancer receiving continuous androgen deprivation therapy. J Urol 178(4):1290–1295
    • (2007) J Urol , vol.178 , Issue.4 , pp. 1290-1295
    • Morote, J.1    Orsola, A.2    Planas, J.3
  • 12
    • 45849139322 scopus 로고    scopus 로고
    • Management of the hormone sensitivity of prostate cancer: where are we now?
    • PID: 18343562
    • Alcaraz A (2008) Management of the hormone sensitivity of prostate cancer: where are we now? Eur Urol 54(2):247–250
    • (2008) Eur Urol , vol.54 , Issue.2 , pp. 247-250
    • Alcaraz, A.1
  • 13
    • 0024218086 scopus 로고
    • Androgen priming and chemotherapy in advanced prostate cancer: evaluation of determinants of clinical outcome
    • COI: 1:STN:280:DyaL1czjt1eqsQ%3D%3D, PID: 3047336
    • Manni A, Bartholomew M, Caplan R et al (1988) Androgen priming and chemotherapy in advanced prostate cancer: evaluation of determinants of clinical outcome. J Clin Oncol 6(9):1456–1466
    • (1988) J Clin Oncol , vol.6 , Issue.9 , pp. 1456-1466
    • Manni, A.1    Bartholomew, M.2    Caplan, R.3
  • 14
    • 34250331066 scopus 로고    scopus 로고
    • Intraprostatic androgens and androgen-regulated gene expression persist after testosterone suppression: therapeutic implications for castration-resistant prostate cancer
    • COI: 1:CAS:528:DC%2BD2sXltl2gtrY%3D, PID: 17510436
    • Mostaghel EA, Page ST, Lin DW et al (2007) Intraprostatic androgens and androgen-regulated gene expression persist after testosterone suppression: therapeutic implications for castration-resistant prostate cancer. Cancer Res 67(10):5033–5041
    • (2007) Cancer Res , vol.67 , Issue.10 , pp. 5033-5041
    • Mostaghel, E.A.1    Page, S.T.2    Lin, D.W.3
  • 15
    • 49249119358 scopus 로고    scopus 로고
    • Maintenance of intratumoral androgens in metastatic prostate cancer: a mechanism for castration-resistant tumor growth
    • COI: 1:CAS:528:DC%2BD1cXmsFKlsr8%3D, PID: 18519708
    • Montgomery RB, Mostaghel EA, Vessella R et al (2008) Maintenance of intratumoral androgens in metastatic prostate cancer: a mechanism for castration-resistant tumor growth. Cancer Res 68(11):4447–4454
    • (2008) Cancer Res , vol.68 , Issue.11 , pp. 4447-4454
    • Montgomery, R.B.1    Mostaghel, E.A.2    Vessella, R.3
  • 16
    • 84892878803 scopus 로고    scopus 로고
    • Castration-resistant prostate cancer: adaptive responses in the androgen axis
    • COI: 1:CAS:528:DC%2BC3sXhs1GrtrjI, PID: 24139549
    • Egan A, Dong Y, Zhang H, Qi Y, Balk SP, Sartor O (2014) Castration-resistant prostate cancer: adaptive responses in the androgen axis. Cancer Treat Rev 40(3):426–433
    • (2014) Cancer Treat Rev , vol.40 , Issue.3 , pp. 426-433
    • Egan, A.1    Dong, Y.2    Zhang, H.3    Qi, Y.4    Balk, S.P.5    Sartor, O.6
  • 17
    • 84938874844 scopus 로고    scopus 로고
    • Philips B, Ball C, Sackett D et al (2009) Oxford Centre for evidence-based medicine levels of evidence
    • Philips B, Ball C, Sackett D et al (2009) Oxford Centre for evidence-based medicine levels of evidence
  • 18
    • 28544432178 scopus 로고    scopus 로고
    • Selective blockade of androgenic steroid synthesis by novel lyase inhibitors as a therapeutic strategy for treating metastatic prostate cancer
    • PID: 16287438
    • Attard G, Belldegrun AS, de Bono JS (2005) Selective blockade of androgenic steroid synthesis by novel lyase inhibitors as a therapeutic strategy for treating metastatic prostate cancer. BJU Int 96(9):1241–1246
    • (2005) BJU Int , vol.96 , Issue.9 , pp. 1241-1246
    • Attard, G.1    Belldegrun, A.S.2    de Bono, J.S.3
  • 19
    • 84863393126 scopus 로고    scopus 로고
    • Effects of abiraterone acetate on androgen signaling in castrate-resistant prostate cancer in bone
    • COI: 1:CAS:528:DC%2BC38Xltlaqsrc%3D, PID: 22184395
    • Efstathiou E, Titus M, Tsavachidou D et al (2012) Effects of abiraterone acetate on androgen signaling in castrate-resistant prostate cancer in bone. J Clin Oncol 30(6):637–643
    • (2012) J Clin Oncol , vol.30 , Issue.6 , pp. 637-643
    • Efstathiou, E.1    Titus, M.2    Tsavachidou, D.3
  • 20
    • 84863011652 scopus 로고    scopus 로고
    • Direct regulation of androgen receptor activity by potent CYP17 inhibitors in prostate cancer cells
    • COI: 1:CAS:528:DC%2BC38XhvVSjtrg%3D, PID: 22174412
    • Soifer HS, Souleimanian N, Wu S et al (2012) Direct regulation of androgen receptor activity by potent CYP17 inhibitors in prostate cancer cells. J Biol Chem 287(6):3777–3787
    • (2012) J Biol Chem , vol.287 , Issue.6 , pp. 3777-3787
    • Soifer, H.S.1    Souleimanian, N.2    Wu, S.3
  • 21
    • 3042784503 scopus 로고    scopus 로고
    • Hormonal impact of the 17alpha-hydroxylase/C(17,20)-lyase inhibitor abiraterone acetate (CB7630) in patients with prostate cancer
    • PID: 15150570
    • O’Donnell A, Judson I, Dowsett M et al (2004) Hormonal impact of the 17alpha-hydroxylase/C(17,20)-lyase inhibitor abiraterone acetate (CB7630) in patients with prostate cancer. Br J Cancer 90(12):2317–2325
    • (2004) Br J Cancer , vol.90 , Issue.12 , pp. 2317-2325
    • O’Donnell, A.1    Judson, I.2    Dowsett, M.3
  • 22
    • 84901188408 scopus 로고    scopus 로고
    • Androgen dynamics and serum PSA in patients treated with abiraterone acetate
    • COI: 1:CAS:528:DC%2BC2cXkvVGrsr4%3D, PID: 24637537
    • Ryan CJ, Peng W, Kheoh T et al (2014) Androgen dynamics and serum PSA in patients treated with abiraterone acetate. Prostate Cancer Prostatic Dis 17(2):192–198
    • (2014) Prostate Cancer Prostatic Dis , vol.17 , Issue.2 , pp. 192-198
    • Ryan, C.J.1    Peng, W.2    Kheoh, T.3
  • 23
    • 79959545655 scopus 로고    scopus 로고
    • The role of abiraterone acetate in the management of prostate cancer: a critical analysis of the literature
    • COI: 1:CAS:528:DC%2BC3MXot1agu7k%3D, PID: 21550166
    • Sonpavde G, Attard G, Bellmunt J et al (2011) The role of abiraterone acetate in the management of prostate cancer: a critical analysis of the literature. Eur Urol 60(2):270–278
    • (2011) Eur Urol , vol.60 , Issue.2 , pp. 270-278
    • Sonpavde, G.1    Attard, G.2    Bellmunt, J.3
  • 24
    • 84879909670 scopus 로고    scopus 로고
    • Pathophysiology and therapy of castration-resistant prostate cancer
    • COI: 1:STN:280:DC%2BC3s7kt1entg%3D%3D, PID: 23160609
    • Merseburger AS, Kuczyk MA, Wolff JM (2013) Pathophysiology and therapy of castration-resistant prostate cancer. Der Urologe Ausg A 52(2):219–225
    • (2013) Der Urologe Ausg A , vol.52 , Issue.2 , pp. 219-225
    • Merseburger, A.S.1    Kuczyk, M.A.2    Wolff, J.M.3
  • 25
    • 0031798627 scopus 로고    scopus 로고
    • A randomised comparison of ‘Casodex’ (bicalutamide) 150 mg monotherapy versus castration in the treatment of metastatic and locally advanced prostate cancer
    • COI: 1:CAS:528:DyaK1cXlsVajtro%3D, PID: 9643663
    • Tyrrell CJ, Kaisary AV, Iversen P et al (1998) A randomised comparison of ‘Casodex’ (bicalutamide) 150 mg monotherapy versus castration in the treatment of metastatic and locally advanced prostate cancer. Eur Urol 33(5):447–456
    • (1998) Eur Urol , vol.33 , Issue.5 , pp. 447-456
    • Tyrrell, C.J.1    Kaisary, A.V.2    Iversen, P.3
  • 26
    • 5444248630 scopus 로고    scopus 로고
    • Bicalutamide 150 mg in addition to standard care in patients with localized or locally advanced prostate cancer: results from the second analysis of the early prostate cancer program at median followup of 5.4 years
    • COI: 1:CAS:528:DC%2BD2cXps12jsrk%3D, PID: 15540740
    • Wirth MP, See WA, McLeod DG et al (2004) Bicalutamide 150 mg in addition to standard care in patients with localized or locally advanced prostate cancer: results from the second analysis of the early prostate cancer program at median followup of 5.4 years. J Urol 172:1865–1870
    • (2004) J Urol , vol.172 , pp. 1865-1870
    • Wirth, M.P.1    See, W.A.2    McLeod, D.G.3
  • 27
    • 0028944138 scopus 로고
    • In vivo amplification of the androgen receptor gene and progression of human prostate cancer
    • COI: 1:CAS:528:DyaK2MXkvV2jurc%3D, PID: 7795646
    • Visakorpi T, Hyytinen E, Koivisto P et al (1995) In vivo amplification of the androgen receptor gene and progression of human prostate cancer. Nat Genet 9(4):401–406
    • (1995) Nat Genet , vol.9 , Issue.4 , pp. 401-406
    • Visakorpi, T.1    Hyytinen, E.2    Koivisto, P.3
  • 28
    • 0033557839 scopus 로고    scopus 로고
    • Survey of gene amplifications during prostate cancer progression by high-throughout fluorescence in situ hybridization on tissue microarrays
    • COI: 1:CAS:528:DyaK1MXht1Sjurc%3D, PID: 10029066
    • Bubendorf L, Kononen J, Koivisto P et al (1999) Survey of gene amplifications during prostate cancer progression by high-throughout fluorescence in situ hybridization on tissue microarrays. Cancer Res 59(4):803–806
    • (1999) Cancer Res , vol.59 , Issue.4 , pp. 803-806
    • Bubendorf, L.1    Kononen, J.2    Koivisto, P.3
  • 29
    • 77951786995 scopus 로고    scopus 로고
    • Prolonged treatment with bicalutamide induces androgen receptor overexpression and androgen hypersensitivity
    • COI: 1:CAS:528:DC%2BC3cXms1Oltbo%3D, PID: 20058237
    • Kawata H, Ishikura N, Watanabe M, Nishimoto A, Tsunenari T, Aoki Y (2010) Prolonged treatment with bicalutamide induces androgen receptor overexpression and androgen hypersensitivity. Prostate 70(7):745–754
    • (2010) Prostate , vol.70 , Issue.7 , pp. 745-754
    • Kawata, H.1    Ishikura, N.2    Watanabe, M.3    Nishimoto, A.4    Tsunenari, T.5    Aoki, Y.6
  • 30
    • 17844376217 scopus 로고    scopus 로고
    • Structural basis for antagonism and resistance of bicalutamide in prostate cancer
    • COI: 1:CAS:528:DC%2BD2MXkt1ClsLs%3D, PID: 15833816
    • Bohl CE, Gao W, Miller DD, Bell CE, Dalton JT (2005) Structural basis for antagonism and resistance of bicalutamide in prostate cancer. Proc Natl Acad Sci USA 102(17):6201–6206
    • (2005) Proc Natl Acad Sci USA , vol.102 , Issue.17 , pp. 6201-6206
    • Bohl, C.E.1    Gao, W.2    Miller, D.D.3    Bell, C.E.4    Dalton, J.T.5
  • 31
    • 84868495700 scopus 로고    scopus 로고
    • FoxA1 corrupts the antiandrogenic effect of bicalutamide but only weakly attenuates the effect of MDV3100 (Enzalutamide)
    • COI: 1:CAS:528:DC%2BC38XhsFymtb%2FO, PID: 23063623
    • Belikov S, Oberg C, Jaaskelainen T, Rahkama V, Palvimo JJ, Wrange O (2013) FoxA1 corrupts the antiandrogenic effect of bicalutamide but only weakly attenuates the effect of MDV3100 (Enzalutamide). Mol Cell Endocrinol 365(1):95–107
    • (2013) Mol Cell Endocrinol , vol.365 , Issue.1 , pp. 95-107
    • Belikov, S.1    Oberg, C.2    Jaaskelainen, T.3    Rahkama, V.4    Palvimo, J.J.5    Wrange, O.6
  • 32
    • 84881102375 scopus 로고    scopus 로고
    • Bone morphogenetic protein-6 induces castration resistance in prostate cancer cells through tumor infiltrating macrophages
    • COI: 1:CAS:528:DC%2BC3sXhtF2qsbzM, PID: 23710822
    • Lee GT, Jung YS, Ha YS, Kim JH, Kim WJ, Kim IY (2013) Bone morphogenetic protein-6 induces castration resistance in prostate cancer cells through tumor infiltrating macrophages. Cancer Sci 104(8):1027–1032
    • (2013) Cancer Sci , vol.104 , Issue.8 , pp. 1027-1032
    • Lee, G.T.1    Jung, Y.S.2    Ha, Y.S.3    Kim, J.H.4    Kim, W.J.5    Kim, I.Y.6
  • 33
    • 84926160408 scopus 로고    scopus 로고
    • Molecular characterization of enzalutamide-treated bone metastatic castration-resistant prostate cancer
    • Efstathiou E, Titus M, Wen S et al (2014) Molecular characterization of enzalutamide-treated bone metastatic castration-resistant prostate cancer. Eur Urol. doi:10.1016/j.eururo.2014.05.005
    • (2014) Eur Urol
    • Efstathiou, E.1    Titus, M.2    Wen, S.3
  • 34
    • 65649090203 scopus 로고    scopus 로고
    • Development of a second-generation antiandrogen for treatment of advanced prostate cancer
    • COI: 1:CAS:528:DC%2BD1MXlsVeksro%3D, PID: 19359544
    • Tran C, Ouk S, Clegg NJ et al (2009) Development of a second-generation antiandrogen for treatment of advanced prostate cancer. Science 324(5928):787–790
    • (2009) Science , vol.324 , Issue.5928 , pp. 787-790
    • Tran, C.1    Ouk, S.2    Clegg, N.J.3
  • 35
    • 84882805666 scopus 로고    scopus 로고
    • Efficacy and safety of enzalutamide (ENZA) monotherapy in hormone-naive prostate cancer (HNPC)
    • Smith MR, Borre M, Rathenborg P et al (2013) Efficacy and safety of enzalutamide (ENZA) monotherapy in hormone-naive prostate cancer (HNPC). J Clin Oncol 31(15):5001
    • (2013) J Clin Oncol , vol.31 , Issue.15 , pp. 5001
    • Smith, M.R.1    Borre, M.2    Rathenborg, P.3
  • 36
    • 44649114728 scopus 로고    scopus 로고
    • Serum testosterone recovery after cessation of long-term luteinizing hormone-releasing hormone agonist in patients with prostate cancer
    • PID: 18279929
    • Bong GW, Clarke HS, Hancock WC, Keane TE (2008) Serum testosterone recovery after cessation of long-term luteinizing hormone-releasing hormone agonist in patients with prostate cancer. Urology 71(6):1177–1180
    • (2008) Urology , vol.71 , Issue.6 , pp. 1177-1180
    • Bong, G.W.1    Clarke, H.S.2    Hancock, W.C.3    Keane, T.E.4
  • 37
    • 38049039454 scopus 로고    scopus 로고
    • A phase II study investigating the re-induction of endocrine sensitivity following chemotherapy in androgen-independent prostate cancer
    • COI: 1:CAS:528:DC%2BD1cXisF2quw%3D%3D, PID: 18182976
    • Shamash J, Davies A, Ansell W et al (2008) A phase II study investigating the re-induction of endocrine sensitivity following chemotherapy in androgen-independent prostate cancer. Br J Cancer 98:22–24
    • (2008) Br J Cancer , vol.98 , pp. 22-24
    • Shamash, J.1    Davies, A.2    Ansell, W.3
  • 38
    • 0027487289 scopus 로고
    • Importance of continued testicular suppression in hormone-refractory prostate cancer
    • COI: 1:STN:280:DyaK2c%2FksFyhsw%3D%3D, PID: 8229130
    • Taylor CD, Elson P, Trump DL (1993) Importance of continued testicular suppression in hormone-refractory prostate cancer. J Clin Oncol 11(11):2167–2172
    • (1993) J Clin Oncol , vol.11 , Issue.11 , pp. 2167-2172
    • Taylor, C.D.1    Elson, P.2    Trump, D.L.3
  • 39
    • 0027944451 scopus 로고
    • Effects of continued androgen-deprivation therapy and other prognostic factors on response and survival in phase II chemotherapy trials for hormone-refractory prostate cancer: a Southwest Oncology Group report
    • COI: 1:STN:280:DyaK2czmsFKgsQ%3D%3D, PID: 8083710
    • Hussain M, Wolf M, Marshall E, Crawford ED, Eisenberger M (1994) Effects of continued androgen-deprivation therapy and other prognostic factors on response and survival in phase II chemotherapy trials for hormone-refractory prostate cancer: a Southwest Oncology Group report. J Clin Oncol 12(9):1868–1875
    • (1994) J Clin Oncol , vol.12 , Issue.9 , pp. 1868-1875
    • Hussain, M.1    Wolf, M.2    Marshall, E.3    Crawford, E.D.4    Eisenberger, M.5
  • 40
    • 79955948091 scopus 로고    scopus 로고
    • Role of androgen deprivation treatment in patients with castration-resistant prostate cancer, receiving docetaxel-based chemotherapy
    • COI: 1:CAS:528:DC%2BC3MXlslWiu7w%3D, PID: 20686407
    • Lee JL, Eun Kim J, Ahn JH et al (2011) Role of androgen deprivation treatment in patients with castration-resistant prostate cancer, receiving docetaxel-based chemotherapy. Am J Clin Oncol 34(2):140–144
    • (2011) Am J Clin Oncol , vol.34 , Issue.2 , pp. 140-144
    • Lee, J.L.1    Eun Kim, J.2    Ahn, J.H.3
  • 41
    • 4744366279 scopus 로고    scopus 로고
    • Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer
    • COI: 1:CAS:528:DC%2BD2cXot1Kmu7s%3D, PID: 15470213
    • Tannock IF, de Wit R, Berry WR et al (2004) Docetaxel plus prednisone or mitoxantrone plus prednisone for advanced prostate cancer. N Engl J Med 351(15):1502–1512
    • (2004) N Engl J Med , vol.351 , Issue.15 , pp. 1502-1512
    • Tannock, I.F.1    de Wit, R.2    Berry, W.R.3
  • 42
    • 41949104346 scopus 로고    scopus 로고
    • Design and end points of clinical trials for patients with progressive prostate cancer and castrate levels of testosterone: recommendations of the Prostate Cancer Clinical Trials Working Group
    • PID: 18309951
    • Scher HI, Halabi S, Tannock I et al (2008) Design and end points of clinical trials for patients with progressive prostate cancer and castrate levels of testosterone: recommendations of the Prostate Cancer Clinical Trials Working Group. J Clin Oncol 26(7):1148–1159
    • (2008) J Clin Oncol , vol.26 , Issue.7 , pp. 1148-1159
    • Scher, H.I.1    Halabi, S.2    Tannock, I.3
  • 43
    • 84873095322 scopus 로고    scopus 로고
    • Androgen-deprivation therapy alone or with docetaxel in non-castrate metastatic prostate cancer (GETUG-AFU 15): a randomised, open-label, phase 3 trial
    • COI: 1:CAS:528:DC%2BC3sXhvFWrsLw%3D, PID: 23306100
    • Gravis G, Fizazi K, Joly F et al (2013) Androgen-deprivation therapy alone or with docetaxel in non-castrate metastatic prostate cancer (GETUG-AFU 15): a randomised, open-label, phase 3 trial. Lancet Oncol 14(2):149–158
    • (2013) Lancet Oncol , vol.14 , Issue.2 , pp. 149-158
    • Gravis, G.1    Fizazi, K.2    Joly, F.3
  • 44
    • 84891687896 scopus 로고    scopus 로고
    • Denosumab and bone metastasis-free survival in men with nonmetastatic castration-resistant prostate cancer: exploratory analyses by baseline prostate-specific antigen doubling time
    • PID: 24043751
    • Smith MR, Saad F, Oudard S et al (2013) Denosumab and bone metastasis-free survival in men with nonmetastatic castration-resistant prostate cancer: exploratory analyses by baseline prostate-specific antigen doubling time. J Clin Oncol 31(30):3800–3806
    • (2013) J Clin Oncol , vol.31 , Issue.30 , pp. 3800-3806
    • Smith, M.R.1    Saad, F.2    Oudard, S.3
  • 45
    • 84866145248 scopus 로고    scopus 로고
    • Flexible trial design in practice—stopping arms for lack-of-benefit and adding research arms mid-trial in STAMPEDE: a multi-arm multi-stage randomized controlled trial
    • PID: 22978443
    • Sydes MR, Parmar MK, Mason MD et al (2012) Flexible trial design in practice—stopping arms for lack-of-benefit and adding research arms mid-trial in STAMPEDE: a multi-arm multi-stage randomized controlled trial. Trials 13:168
    • (2012) Trials , vol.13 , pp. 168
    • Sydes, M.R.1    Parmar, M.K.2    Mason, M.D.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.