Safety and immunogenicity of a delta inulin-adjuvanted inactivated Japanese encephalitis virus vaccine in pregnant mares and foals

Veterinary Research

Volumn 45, Issue 1, 2014, Pages

  Bielefeldt Ohmann, Helle ^a   Prow, Natalie A ^a   Wang, Wenqi ^a   Tan, Cindy S E ^a   Coyle, Mitchell ^a   Douma, Alysha ^a   Hobson Peters, Jody ^a   Kidd, Lisa ^a   Hall, Roy A ^a   Petrovsky, Nikolai ^b,c  

^a UNIVERSITY OF QUEENSLAND   (Australia)

^b VAXINE PTY LTD   (Australia)

^c FLINDERS UNIVERSITY   (Australia)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOLOGICAL ADJUVANT; INULIN; VIRUS ANTIBODY; VIRUS VACCINE;

ANIMAL; CROSS REACTION; ENCEPHALITIS, JAPANESE; FEMALE; HORSE; HORSE DISEASES; IMMUNOLOGY; JAPANESE ENCEPHALITIS VIRUS; PHYSIOLOGY; PREGNANCY; VETERINARY; VIROLOGY;

ADJUVANTS, IMMUNOLOGIC; ANIMALS; ANTIBODIES, VIRAL; CROSS REACTIONS; ENCEPHALITIS VIRUS, JAPANESE; ENCEPHALITIS, JAPANESE; FEMALE; HORSE DISEASES; HORSES; INULIN; PREGNANCY; VIRAL VACCINES;

EID: 84938866924     PISSN: 09284249     EISSN: 12979716     Source Type: Journal    
DOI: 10.1186/s13567-014-0130-7     Document Type: Article

References (54)

1. Mackenzie JS, Lindsay MD, Coelen RJ, Broom AK, Hall RA, Smith DW: Arboviruses causing human disease in the Australasian zoogeographic region. Arch Virol 1994, 136:447-467.
2. Mackenzie JS, Johansen CA, Ritchie SA, van den Hurk AF, Hall RA: Japanese encephalitis as an emerging virus: the emergence and spread of Japanese encephalitis virus in Australasia. Curr Top Microbiol Immunol 2002, 267:49-73.
3. Solomon T: Flavivirus encephalitis. N Engl J Med 2004, 351:370-378.
4. Gould DJ, Byrne RJ, Hayes DE: Experimental infection of horses with Japanese encephalitis virus by mosquito bits. Am J Trop Med Hyg 1964, 13:742-746.
5. Lam KH, Ellis TM, Williams DT, Lunt RA, Daniels PW, Watkins KL, Riggs CM: Japanese encephalitis in a racing thoroughbred gelding in Hong Kong. Vet Rec 2005, 157:168-173.
6. Miyake M: The pathology of Japanese encephalitis. A review. Bull World Hlth Organ 1964, 30:153-160.
7. Yamanaka T, Tsujimura K, Kondo T, Yasuda W, Okada A, Noda K, Okumura T, Matsumura T: Isolation and genetic analysis of Japanese encephalitis virus from a diseased horse in Japan. J Vet Med Sci 2006, 68:293-295.
8. Konishi E, Shoda M, Kondo T: Analysis of yearly changes in levels of antibodies to Japanese encephalitis virus nonstructural 1 protein in racehorses in central Japan shows high levels of natural virus activity still exist. Vaccine 2006, 24:516-524.
9. Monath TP: Japanese encephalitis vaccines: current vaccines and future prospects. Curr Top Microbiol Immunol 2002, 267:105-138.
10. Tsai TF: New initiatives for the control of Japanese encephalitis by vaccination: minutes of a WHO/CVI meeting, Bangkok, Thailand, 13-15 October 1998. Vaccine 2000, 18(Suppl 2):1-25.
11. Fischer M, Casey C, Chen RT: Promise of new Japanese encephalitis vaccines. Lancet 2007, 370:1806-1808.
12. RIRDC 2006: Rural Industries Research & Development Corporations - Horse R&D Plan 2006-2011. [ https://rirdc.infoservices.com.au/items/06-114 ]
13. Lobigs M, Pavy M, Hall RA, Lobigs P, Cooper P, Komiya T, Toriniwa H, Petrovsky N: An inactivated Vero cell-grown Japanese encephalitis vaccine formulated with Advax, a novel inulin-based adjuvant, induces protective neutralizing antibody against homologous and heterologous flaviviruses. J Gen Virol 2010, 91:1407-1417.
14. Frost MJ, Zhang J, Edmonds JH, Prow NA, Gu X, Davis R, Hornitzky C, Arzey KE, Finlayson D, Hick P, Read A, Hobson-Peters J, May FJ, Doggett SL, Haniotis J, Russell RC, Hall RA, Khromykh AA, Kirkland PD: Characterization of virulent West Nile virus Kunjin strain, Australia, 2011. Emerg Infect Dis 2012, 18:792-800.
15. Roche SE, Wicks R, Garner MG, East IJ, Paskin R, Moloney BJ, Carr M, Kirkland P: Descriptive overview of the 2011 epidemic of arboviral disease in horses in Australia. Aust Vet J 2012, 91:5-13.
16. Toriniwa H, Komiya T: Long-term stability of Vero cell-derived inactivated Japanese encephalitis vaccine prepared using serum-free medium. Vaccine 2008, 26:3680-3689.
17. Cooper P, Petrovsky N: Delta inulin: a novel, immunologically-active, stable packing structure comprising β-D-[2→1] polyfructo-furanosyl α-D glucose polymers. Glycobiology 2011, 21:595-606.
18. Prow NA, Tan CSE, Wang W, Hobson-Peters J, Kidd L, Barton A, Hall RA, Bielefeldt-Ohmann H: Natural exposure of horses to mosquito-borne flaviviruses in South-East Queensland, Australia. Int J Environ Res Public Health 2013, 10:4432-4443.
19. Hall RA, Broom AK, Hartnett AC, Howard MJ, Mackenzie JS: Immunodominant epitopes on the NS1 protein of MVE and KUN viruses serve as targets for a blocking ELISA to detect virus specific antibodies in sentinel animal serum. J Virol Methods 1995, 51:201-210.
20. Blitvitch BJ, Bowen RA, Marlenee NL, Hall RA, Bunning ML, Beaty BJ: Epitope-blocking enzyme-linked immunosorbent assays for detection of West Nile virus antibodies in domestic mammals. J Clin Microbiol 2003, 41:2676-2679.
21. APVMA. 2014. Australian Pesticides and Veterinary Medicines Authority - Guiidelines for registration of new veterinary vaccines [ http://apvma.gov.au/node/1041 ]
22. Barton AJ, Prow NA, Hall RA, Kidd L, Bielefeldt-Ohmann H: A case of Murray Valley encephalitis in a two-year old Australian stock horse in South-East Queensland. Aus Vet J, in press.
23. Prow NA, Hewlett EK, Faddy HM, Coiacetto F, Wang W, Cox T, Hall RA, Bielefeldt-Ohmann H: The Australian public is still vulnerable to emerging virulent strains of West Nile virus. Front Public Health 2014, 2:146.
24. Petrovsky N, Larena M, Siddharthan V, Prow NA, Hall RA, Lobigs M, Morrey J: An inactivated cell culture Japanese encephalitis vaccine (JE-ADVAX) formulated with delta inulin adjuvant provides robust heterologous protection against West Nile encephalitis via cross-protective memory B cells and neutralizing antibody. J Virol 2013, 87:10324-10333.
25. Lobigs M, Larena M, Alsharifi M, Lee E, Pavy M: Live chimeric and inactivated Japanese encephalitis virus vaccines differ in their cross-protective values against Murray Valley encephalitis virus. J Virol 2009, 83:2436-2445.
26. Karaqianni AE, Kapetanovic R, McGorum BC, Hume DA, Pirie SR: The equine alveolar macrophage: functional and phenotypic comparisons with peritoneal macrophages. Vet Immunol Immunopathol 2013, 155:219-228.
27. Gard GP, Marshall ID, Walker KH, Acland HM, Saren WG: Association of Australian arboviruses with nervous disease in horses. Aust Vet J 1977, 53:61-66.
28. Gordon AN, Marbach CR, Oakey J, Edmunds G, Condon K, Diviney SM, Williams DT, Bingham J: Confirmed case of encephalitis caused by Murray Valley encephalitis virus infection in a horse. J Vet Diagn Invest 2012, 24:431-436.
29. Holmes JM, Gilkerson JR, El Hage CM, Slocombe RF, Muurlink MA: Murray Valley encephalomyelitis in a horse. Aust Vet J 2012, 90:252-254.
30. Selvey LA, Dailey L, Lindsay M, Armstrong P, Tobin S, Koehler AP, Markey PG, Smith DW: The changing epidemiology of Murray Valley encephalitis in Australia: the 2011 outbreak and a review of the literature. PLoS Negl Trop Dis 2014, 8:e2556.
31. Poidinger M, Hall RA, Mackenzie JS: Molecular characterization of the Japanese encephalitis serocomplex of the flavivirus genus. Virology 1996, 218:417-421.
32. Blasco E, Lambot M, Barrat J, Cliquet F, Brochier B, Renders C, Krafft N, Bailly J, Munier M, Pastoret P-P, Aubert MFA: Kinetics of humoral immune response after rabies VR-G oral vaccination of captive fox cubs (Vulpes vulpes) with or without maternally derived antibodies against the vaccine. Vaccine 2001, 19:4805-4815.
33. Endsley JJ, Roth JA, Ridpath J, Neill J: Maternal antibody blocks humoral but not T cell responses to BVDV. Biologicals 2003, 31:123-125.
34. Filho OA, Megid J, Geronutti L, Ratti J Jr, Almeida MFA, Kataoka APAG, Martorelli LFA: Vaccine immune response and interference of colostral antibodies in calves vaccinated against rabies at 2, 4 and 6 months of age born from antirabies revaccinated females. Res Vet Sci 2012, 92:396-400.
35. Hodgins DC, Shewen PE: Vaccination of neonates: problem and issues. Vaccine 2012, 30:1541-1559.
36. Oura CAL, Wood JLN, Floyd T, Sanders AJ, Bin-Tarif A, Henstock M, Edwards L, Simmons H, Batten CA: Colostral antibody protection and interference with immunity in lambs born from sheep vaccinated with an inactivated Bluetongue serotype 8 vaccine. Vaccine 2010, 28:2749-2753.
37. Siegrist CA: The challenges of vaccine responses in early life: selected examples. J Comp Pathol 2007, 137(Suppl 1):S4-S9.
38. Siegrist CA, Lambert PH: Maternal immunity and infant responses to immunization: factors influencing infant responses. Dev Biol Stand 1998, 95:133-139.
39. Wilkins PA, Glasser AL, McDonnell SM: Passive transfer of naturally acquired specific immunity against West Nile virus to foals in a semi-feral pony herd. J Vet Intern Med 2006, 20:1045-1047.
40. Brown AN, Kent KA, Bennett CJ, Bernard KA: Tissue tropism and neuroinvasion of West Nile virus do not differ for two mouse strains with different survival rates. Virology 2007, 368:422-430.
41. Weiner LP, Cole GA, Nathanson N: Experimental encephalitis following peripheral inoculation of West Nile virus in mice of different ages. J Hyg (Lond) 1970, 68:435-446.
42. Suen WW, Prow NA, Hall RA, Bielefeldt-Ohmann H: Mechanism of West Nile virus neuroinvasion: a critical appraisal. Viruses 2014, 6:2796-2825.
43. Shirafuji H, Kanehira K, Kamio T, Kubo T, Shibahara T, Konishi M, Murakami K, Nakamura Y, Yamanaka T, Kondo T, Matsumura T, Muranaka M, Katayama Y: Antibody responses induced by experimental West Nile virus infection with or without previous immunization with inactivated Japanese encephalitis vaccine in horses. J Vet Med Sci 2009, 71:969-974.
44. Larena M, Prow NA, Hall RA, Petrovsky N, Lobigs M: JE-ADVAX vaccine protection against Japanese encephalitis virus mediated by memory B cells in the absence of CD8(+) T cells and pre-exposure neutralizing antibody. J Virol 2013, 87:4395-4402.
45. Angenvoort J, Brault AC, Bowen RA, Groschup MH: West Nile viral infection of equids. Vet Microbiol 2013, 167:168-180.
46. Bowen RA, Nemeth NM: Experimental infections with West Nile virus. Curr Opin Infect Dis 2007, 20:293-297.
47. Ellis PM, Daniels PW, Banks DJ: Japanese encephalitis. Vet Clin North Am Equine Pract 2000, 16:565-578.
48. Long MT, Gibbs EPJ, Mellemcamp MW, Bowen RA, Seino KK, Zhang S, Beachboard SE, Humphrey PP: Efficacy, duration, and onset of immunogenicity of a West Nile virus vaccine, live Flavivirus chimera, in horses with a clinical disease challenge model. Equine Vet J 2007, 39:491-497.
49. Kay BH, Pollitt CC, Fanning ID, Hall RA: The experimental infection of horses with Murray Valley encephalitis and Ross River viruses. Aust Vet J 1987, 64:52-55.
50. Seino KK, Long MT, Gibbs EP, Bowen RA, Beachboard SE, Humphrey PP, Dixon MA, Bourgeois MA: Comparative efficacies of three commercially available vaccines against West Nile Virus (WNV) in a short-duration challenge trial involving an equine WNV encephalitis model. Clin Vaccine Immunol 2007, 14:1465-1471.
51. Brandler S, Tangy F: Vaccines in development against West Nile virus. Viruses 2013, 5:2384-2409.
52. Hall RA, Nisbet DJ, Pham KB, Pyke AT, Smith GA, Khromykh AA: DNA vaccine coding for the full-length infectious Kunjin virus RNA protects mice against the New York strain of West Nile virus. Proc Natl Acad Sci U S A 2003, 100:10460-10464.
53. Roby JA, Bielefeldt-Ohmann H, Prow NA, Chang DC, Hall RA, Khromykh AA: Increased expression of capsid protein in trans enhances production of single-round infectious particles by a West Nile virus DNA vaccine. J Gen Virol 2014, 95:2176-2191.
54. Siger L, Bowen RA, Karaca K, Murray MJ, Gordy PW, Loosmore SM, Audonnet JC, Nordgren RM, Minke JM: Assessment of the efficacy of a single dose of a recombinant vaccine against West Nile virus in response to natural challenge with West Nile virus-infected mosquitoes in horses. Am J Vet Res 2004, 65:1459-1462.