Shared segment analysis and next-generation sequencing implicates the retinoic acid signaling pathway in Total Anomalous Pulmonary Venous Return (TAPVR)

PLoS ONE

Volumn 10, Issue 6, 2015, Pages

  Nash, Dustin ^a   Arrington, Cammon B ^a   Kennedy, Brett J ^a   Yandell, Mark ^a,b   Wu, Wilfred ^a   Zhang, Wenying ^c   Ware, Stephanie ^c   Jorde, Lynn B ^a   Gruber, Peter J ^a,e   Yost, H Joseph ^a   Bowles, Neil E ^a   Bleyl, Steven B ^a,d  

^a UNIVERSITY OF UTAH SCHOOL OF MEDICINE   (United States)

^b USTAR Center for Genetic Discovery   (United States)

^c CINCINNATI CHILDREN'S HOSPITAL MEDICAL CENTER   (United States)

^d Clinical Genetics Institute   (United States)

^e UNIVERSITY OF IOWA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

MESSENGER RNA; RETINOIC ACID; MORPHOLINO OLIGONUCLEOTIDE; ZEBRAFISH PROTEIN;

ADULT; ANIMAL EXPERIMENT; ANIMAL TISSUE; ANKRD1 GENE; ARTICLE; CARP GENE; CHROMOSOME 12; CONTROLLED STUDY; EMBRYO; GENE; GENE EXPRESSION; GENE SEQUENCE; GENOTYPE; GREAT VESSELS TRANSPOSITION; HEART ATRIUM SEPTUM DEFECT; HEART RIGHT VENTRICLE DOUBLE OUTLET; HEART VENTRICLE SEPTUM DEFECT; HERITABILITY; HUMAN; IMMUNOHISTOCHEMISTRY; IN SITU HYBRIDIZATION; INFANT; LUNG VEIN DRAINAGE ANOMALY; MAJOR CLINICAL STUDY; NEXT GENERATION SEQUENCING; NONHUMAN; PDGFRA GENE; PHENOTYPE; RBP5 GENE; SIGNAL TRANSDUCTION; SINGLE NUCLEOTIDE POLYMORPHISM; SINUS NODE DISEASE; ZEBRA FISH; ANIMAL; EMBRYOLOGY; FEMALE; GENE EXPRESSION REGULATION; GENE FREQUENCY; GENE SILENCING; GENETIC VARIATION; GENETICS; HEART; HIGH THROUGHPUT SEQUENCING; MALE; METABOLISM; PEDIGREE; PHYSIOLOGY; PROCEDURES; SCIMITAR SYNDROME; SOFTWARE;

DANIO RERIO;

ANIMALS; CHROMOSOMES, HUMAN, PAIR 12; FEMALE; GENE EXPRESSION REGULATION, DEVELOPMENTAL; GENE FREQUENCY; GENE KNOCKDOWN TECHNIQUES; GENETIC VARIATION; HEART; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; MALE; MORPHOLINOS; PEDIGREE; SCIMITAR SYNDROME; SIGNAL TRANSDUCTION; SOFTWARE; TRETINOIN; ZEBRAFISH; ZEBRAFISH PROTEINS;

EID: 84938702835     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0131514     Document Type: Article

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