Elevated Tau Level in Aged Rat Cerebrospinal Fluid Reduced by Treatment with a Neurotrophic Compound

Journal of Alzheimer's Disease

Volumn 47, Issue 3, 2015, Pages 557-564

  Khatoon, Sabiha ^a   Chalbot, Sonia ^a   Bolognin, Silvia ^a   Puoliväli, Jukka ^b   Iqbal, Khalid ^a  

^a NEW YORK STATE INSTITUTE FOR BASIC RESEARCH IN DEVELOPMENTAL DISABILITIES   (United States)

^b Charles River Discovery Research Services   (Finland)

Author keywords

Aged Fisher rat; Alzheimer's disease; cerebral aging; cerebrospinal fluid; ELISA; rat; tau protein

Indexed keywords

NEUROTROPHIC FACTOR; P 021; TAU PROTEIN; UNCLASSIFIED DRUG; ADAMANTANE; AMYLOID PRECURSOR PROTEIN; BIOLOGICAL MARKER; MAPT PROTEIN, HUMAN; MAPT PROTEIN, RAT; NOOTROPIC AGENT; OLIGOPEPTIDE; P021 PEPTIDE; RECOMBINANT PROTEIN;

ADULT; AGED; AGING; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; CLINICAL TRIAL (TOPIC); CONTROLLED STUDY; DRUG CEREBROSPINAL FLUID LEVEL; DRUG EFFICACY; DRUG PENETRATION; DRUG POTENCY; FEMALE; IMMUNITY; NONHUMAN; PRIORITY JOURNAL; RAT; YOUNG ADULT; ALZHEIMER DISEASE; ANALOGS AND DERIVATIVES; ANIMAL; BRAIN CORTEX; CEREBROSPINAL FLUID; DISEASE MODEL; DRUG EFFECTS; ENZYME LINKED IMMUNOSORBENT ASSAY; FISCHER 344 RAT; HIPPOCAMPUS; HUMAN; IMMUNOBLOTTING; METABOLISM; ORAL DRUG ADMINISTRATION; TREATMENT OUTCOME; WESTERN BLOTTING;

ADAMANTANE; ADMINISTRATION, ORAL; AGING; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BIOMARKERS; BLOTTING, WESTERN; CEREBRAL CORTEX; DISEASE MODELS, ANIMAL; ENZYME-LINKED IMMUNOSORBENT ASSAY; FEMALE; HIPPOCAMPUS; HUMANS; IMMUNOBLOTTING; NOOTROPIC AGENTS; OLIGOPEPTIDES; RATS, INBRED F344; RECOMBINANT PROTEINS; TAU PROTEINS; TREATMENT OUTCOME;

EID: 84938692829     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-142799     Document Type: Article

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