Daily oxygen/O3 treatment reduces muscular fatigue and improves cardiac performance in rats subjected to prolonged high intensity physical exercise

Oxidative Medicine and Cellular Longevity

Volumn 2015, Issue , 2015, Pages

  Di Filippo, C ^a   Trotta, M C ^a   Maisto, R ^a   Siniscalco, D ^a   Luongo, M ^a   Mascolo, L ^a   Alfano, R ^a   Accardo, M ^a   Rossi, C ^a   Ferraraccio, F ^a   D'Amico, M ^a  

^a SECOND UNIVERSITY OF NAPLES   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BLOOD PRESSURE; HEART; RATS; THICKNESS MEASUREMENT;

ANTIOXIDANT ENZYME; BENEFICIAL EFFECTS; CARDIAC HYPERTROPHY; DIASTOLIC FUNCTION; INTRAPERITONEAL ADMINISTRATION; LEFT VENTRICULAR MASS; MEAN ARTERIAL BLOOD PRESSURES; PHYSICAL EXERCISE;

OXYGEN;

3 NITROTYROSINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GLUTATHIONE PEROXIDASE 1; MANGANESE SUPEROXIDE DISMUTASE; OXYGEN; OZONE; PEROXYNITRITE; CREATINE KINASE; GLUTATHIONE PEROXIDASE; LACTATE DEHYDROGENASE; SUPEROXIDE DISMUTASE; TROPONIN I;

ADAPTATION; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; CONTROLLED STUDY; DOSE RESPONSE; DRUG DOSE COMPARISON; DRUG DOSE INCREASE; EXERCISE INTENSITY; GASTROCNEMIUS MUSCLE; HEART HYPERTROPHY; HEART LEFT VENTRICLE MASS; HEART PERFORMANCE; HEART RATE; HEART VENTRICLE HYPERTROPHY; MALE; MEAN ARTERIAL PRESSURE; MUSCLE FATIGUE; NONHUMAN; OXIDATIVE STRESS; OXYGEN CONSUMPTION; OZONE THERAPY; PROLONGED HIGH INTENSITY EXERCISE; RAT; SPRAGUE DAWLEY RAT; TRANSTHORACIC ECHOCARDIOGRAPHY; TREADMILL EXERCISE; ANIMAL; BLOOD PRESSURE; DRUG EFFECTS; FIBROSIS; HEMODYNAMICS; HYPERTROPHY; METABOLISM; PATHOLOGY; SKELETAL MUSCLE;

RATTUS;

ANIMALS; BLOOD PRESSURE; CREATINE KINASE; FIBROSIS; GLUTATHIONE PEROXIDASE; HEART RATE; HEMODYNAMICS; HYPERTROPHY; L-LACTATE DEHYDROGENASE; MALE; MUSCLE FATIGUE; MUSCLE, SKELETAL; NITRIC OXIDE SYNTHASE TYPE III; OXYGEN; OZONE; PHYSICAL CONDITIONING, ANIMAL; RATS; RATS, SPRAGUE-DAWLEY; SUPEROXIDE DISMUTASE; TROPONIN I;

EID: 84938630360     PISSN: 19420900     EISSN: 19420994     Source Type: Journal    
DOI: 10.1155/2015/190640     Document Type: Article

References (30)

1. O. J. Kemi, P. M. Haram, J. P. Loennechen, et al., "Moderate vs. high exercise intensity: differential effects on aerobic fitness, cardiomyocyte contractility, and endothelial function, " Cardiovascular Research, vol. 67, no. 1, pp. 161-172, 2005.
2. B. M. Pluim, A. H. Zwinderman, A. van der Laarse, and E. E. van der Wall, "The athletes heart: a meta-analysis of cardiac structure and function, " Circulation, vol. 101, no. 3, pp. 336-344, 2000.
3. K. J. A. Davies, A. T. Quintanilha, G. A. Brooks, and L. Packer, "Free radicals and tissue damage produced by exercise, " Biochemical and Biophysical Research Communications, vol. 107, no. 4, pp. 1198-1205, 1982.
4. T. Ashton, C. C. Rowland s, E. Jones, et al., "Electron spin resonance spectroscopic detection of oxygen-centred radicals in human serum following exhaustive exercise, " European Journal of Applied Physiology and Occupational Physiology, vol. 77, no. 6, pp. 498-502, 1998.
5. T. Ashton, I. S. Young, J. R. Peters, et al., "Electron spin resonance spectroscopy, exercise, and oxidative stress: an ascorbic acid intervention study, " Journal of Applied Physiology, vol. 87, no. 6, pp. 2032-2036, 1999.
6. W. L. Knez, D. G. Jenkins, and J. S. Coombes, "Oxidative stress in half and full Ironman triathletes, "Medicine and Science in Sports and Exercise, vol. 39, no. 2, pp. 283-288, 2007.
7. A. M. Elvis and J. S. Ekta, "Ozone therapy: a clinical review, " Journal of Natural Science, Biology and Medicine, vol. 2, no. 1, pp. 66-70, 2011.
8. Z. Razumovskii, "Ozone and its reactions with organic compounds, " 1984, http://ozonicsint.com/articlesvivo.html.
9. L. J. Folinsbee, "Effects of ozone exposure on lung function in man, " Reviews on Environmental Health, vol. 3, no. 3, pp. 211-240, 1981.
10. V. Bocci, "Biological and clinical effects of ozone. Has ozone therapy a future in medicine?" British Journal of Biomedical Science, vol. 56, no. 4, pp. 270-279, 1999.
11. V. Bocci, "Does ozone therapy normalize the cellular redox balance? Implications for the therapy of human immunodeficiency virus infection and several other diseases, " Medical Hypotheses, vol. 46, no. 2, pp. 150-154, 1996.
12. V. Bocci, "How a calculated oxidative stress can yield multiple therapeutic effects, " Free Radical Research, vol. 46, no. 9, pp. 1068-1075, 2012.
13. E. Borrelli and V. Bocci, "A novel terapeutic option for Chronic Fatigue Syndrome and Fibromyalgia, " Rivista Italiana di Ossigeno-Ozonoterapia, vol. 1, pp. 149-153, 2002.
14. C. Di Filippo, R. Marfella, P. Capodanno, et al., "Acute oxygenozone administration to rats protects the heart from ischemia reperfusion infarct, " Inflammation Research, vol. 57, no. 10, pp. 445-449, 2008.
15. A. D. C. Lana, C. A. Paulino, and I. D. Gonçalves, "Influence of low and high intensity physical exercise on hypernociception threshold and other parameters of rats, " Revista Brasileira de Medicina do Esporte, vol. 12, no. 5, 2006.
16. L. Coppola, R. Giunta, G. Verrazzo, et al., "Influence of ozone on haemoglobin oxygen affinity in type-2 diabetic patients with peripheral vascular disease: in vitro studies, " Diabete et Metabolisme, vol. 21, no. 4, pp. 252-255, 1995.
17. H. Chen, B. Xing, X. Liu, et al., "Ozone oxidative preconditioning protects the rat kidney from reperfusion injury: the role of nitric oxide, " Journal of Surgical Research, vol. 149, no. 2, pp. 287-295, 2008.
18. M. D. Morsy, W. N. Hassan, and S. I. Zalat, "Improvement of renal oxidative stress markers after ozone administration in diabetic nephropathy in rats, " Diabetology & Metabolic Syndrome, vol. 2, article 29, 2010.
19. A. Torossian, S. Ruehlmann, L. Eberhart, M. Middeke, H. Wulf, and A. Bauhofer, "Pre-treatment with ozonized oxygen (O3) aggravates inflammation in septic rats, " Inflammation Research, vol. 53, no. 2, pp. S122-S125, 2004.
20. L. Re, M. N. Mawsouf, S. Menéndez, O. S. León, G. M. Sánchez, and F. Hernánd ez, "Ozone therapy: clinical and basic evidence of its therapeutic potential, " Archives of Medical Research, vol. 39, no. 1, pp. 17-26, 2008.
21. L. M. Bellamy, S. Joanisse, A. Grubb, et al., "The acute satellite cell response and skeletal muscle hypertrophy following resistance training, " PLoS ONE, vol. 9, no. 10, Article ID e109739, 2014.
22. F. Hernand ez, S. Menendez, and R. Wong, "Decrease of blood cholesterol and stimulation of antioxidative response on cardiopathy patients treated with endovenous ozone therapy, " Free Radical Biology & Medicine, vol. 19, pp. 115-119, 1995.
23. V. Bocci and G. Valacchi, "Nrf2 activation as target to implement therapeutic treatments, " Frontiers in Chemistry, vol. 3, article 4, 2015.
24. E. W. J. A. Albrecht, C. A. Stegeman, P. Heeringa, R. H. Henning, and H. van Goor, "Protective role of endothelial nitric oxide synthase, "TheJournal of Pathology, vol. 199, no. 1, pp. 8-17, 2003.
25. B. G. Hill, B. P. Dranka, S. M. Bailey, J. R. Lancaster Jr., and V. M. Darley-Usmar, "What part of NO dont you understand ? Some answers to the cardinal questions in nitric oxide biology, " The Journal of Biological Chemistry, vol. 285, no. 26, pp. 19699-19704, 2010.
26. C. Villanueva and C. Giulivi, "Subcellular and cellular locations of nitric oxide synthase isoforms as determinants of health and disease, " Free Radical Biology and Medicine, vol. 49, no. 3, pp. 307-316, 2010.
27. J. P. Cooke and V. J. Dzau, "Derangements of the nitric oxide synthase pathway, L-arginine, and cardiovascular diseases, " Circulation, vol. 96, no. 2, pp. 379-382, 1997.
28. J. S. Beckman and W. H. Koppenol, "Nitric oxide, superoxide, and peroxynitrite: the good, the bad, and the ugly, " American Journal of Physiology: Cell Physiology, vol. 271, no. 5, pp. C1424-C1437, 1996.
29. R. Zamora, Y. Vodovotz, and T. R. Billiar, "Inducible nitric oxide synthase and inflammatory diseases, " Molecular Medicine, vol. 6, no. 5, pp. 347-373, 2000.
30. A. Chatterjee and J. D. Catravas, "Endothelial nitric oxide (NO) and its pathophysiologic regulation, " Vascular Pharmacology, vol. 49, no. 4-6, pp. 134-140, 2008.