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Volumn 50, Issue 4, 2015, Pages 414-423

Epithelial-derived nuclear IL-33 aggravates inflammation in the pathogenesis of reflux esophagitis

Author keywords

Epithelial cell; IL 33; Inflammation; Reflux esophagitis

Indexed keywords

AUTACOID; GAMMA INTERFERON; INTERLEUKIN 33; INTERLEUKIN DERIVATIVE; MESSENGER RNA; SMALL INTERFERING RNA;

EID: 84938600978     PISSN: 09441174     EISSN: 14355922     Source Type: Journal    
DOI: 10.1007/s00535-014-0988-1     Document Type: Article
Times cited : (29)

References (38)
  • 1
    • 70350092411 scopus 로고    scopus 로고
    • Gastroesophageal reflux might cause esophagitis through a cytokine-mediated mechanism rather than caustic acid injury
    • COI: 1:CAS:528:DC%2BD1MXhsVyhsbzI, PID: 19660463
    • Souza RF, Huo X, Mittal V, et al. Gastroesophageal reflux might cause esophagitis through a cytokine-mediated mechanism rather than caustic acid injury. Gastroenterology. 2009;137:1776–84.
    • (2009) Gastroenterology , vol.137 , pp. 1776-1784
    • Souza, R.F.1    Huo, X.2    Mittal, V.3
  • 2
    • 77951489928 scopus 로고    scopus 로고
    • Inflammatory mediators in gastroesophageal reflux disease: impact on esophageal motility, fibrosis, and carcinogenesis
    • COI: 1:CAS:528:DC%2BC3cXmtlWjt7Y%3D, PID: 20299604
    • Rieder F, Biancani P, Harnett K, et al. Inflammatory mediators in gastroesophageal reflux disease: impact on esophageal motility, fibrosis, and carcinogenesis. Am J Physiol Gastrointest Liver Physiol. 2010;298:G571–81.
    • (2010) Am J Physiol Gastrointest Liver Physiol , vol.298 , pp. 571-581
    • Rieder, F.1    Biancani, P.2    Harnett, K.3
  • 3
    • 84869171924 scopus 로고    scopus 로고
    • Trypsin impaired epithelial barrier function and induced IL-8 secretion through basolateral PAR-2: a lesson from a stratified squamous epithelial model
    • COI: 1:CAS:528:DC%2BC38XhvVKmtbvM, PID: 22997195
    • Shan J, Oshima T, Chen X, et al. Trypsin impaired epithelial barrier function and induced IL-8 secretion through basolateral PAR-2: a lesson from a stratified squamous epithelial model. Am J Physiol Gastrointest Liver Physiol. 2012;303:G1105–12.
    • (2012) Am J Physiol Gastrointest Liver Physiol , vol.303 , pp. 1105-1112
    • Shan, J.1    Oshima, T.2    Chen, X.3
  • 4
    • 84876993636 scopus 로고    scopus 로고
    • Acidic deoxycholic acid and chenodeoxycholic acid induce interleukin-8 production through p38 mitogen-activated protein kinase and protein kinase A in a squamous epithelial model
    • COI: 1:CAS:528:DC%2BC3sXmslSmtLo%3D, PID: 23425072
    • Shan J, Oshima T, Fukui H, et al. Acidic deoxycholic acid and chenodeoxycholic acid induce interleukin-8 production through p38 mitogen-activated protein kinase and protein kinase A in a squamous epithelial model. J Gastroenterol Hepatol. 2013;28:823–8.
    • (2013) J Gastroenterol Hepatol , vol.28 , pp. 823-828
    • Shan, J.1    Oshima, T.2    Fukui, H.3
  • 5
    • 84865750184 scopus 로고    scopus 로고
    • HCl-induced and ATP-dependent upregulation of TRPV1 receptor expression and cytokine production by human esophageal epithelial cells
    • COI: 1:CAS:528:DC%2BC38XhsFGlsrrE, PID: 22790593
    • Ma J, Altomare A, Guarino M, et al. HCl-induced and ATP-dependent upregulation of TRPV1 receptor expression and cytokine production by human esophageal epithelial cells. Am J Physiol Gastrointest Liver Physiol. 2012;303:G635–45.
    • (2012) Am J Physiol Gastrointest Liver Physiol , vol.303 , pp. 635-645
    • Ma, J.1    Altomare, A.2    Guarino, M.3
  • 6
    • 27744446058 scopus 로고    scopus 로고
    • IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines
    • COI: 1:CAS:528:DC%2BD2MXht12msr7K, PID: 16286016
    • Schmitz J, Owyang A, Oldham E, et al. IL-33, an interleukin-1-like cytokine that signals via the IL-1 receptor-related protein ST2 and induces T helper type 2-associated cytokines. Immunity. 2005;23:479–90.
    • (2005) Immunity , vol.23 , pp. 479-490
    • Schmitz, J.1    Owyang, A.2    Oldham, E.3
  • 7
    • 84867859899 scopus 로고    scopus 로고
    • Regulation of IL-33 expression by IFN-γ and tumor necrosis factor-α in normal human epidermal keratinocytes
    • COI: 1:CAS:528:DC%2BC38Xot1Chsrs%3D, PID: 22673732
    • Meephansan J, Tsuda H, Komine M, et al. Regulation of IL-33 expression by IFN-γ and tumor necrosis factor-α in normal human epidermal keratinocytes. J Invest Dermatol. 2012;132:2593–600.
    • (2012) J Invest Dermatol. , vol.132 , pp. 2593-2600
    • Meephansan, J.1    Tsuda, H.2    Komine, M.3
  • 8
    • 84876069196 scopus 로고    scopus 로고
    • A novel interleukin 33/ST2 signaling regulates inflammatory response in human corneal epithelium
    • COI: 1:CAS:528:DC%2BC3sXmsVKqtbk%3D, PID: 23585867
    • Lin J, Zhang L, Zhao G, et al. A novel interleukin 33/ST2 signaling regulates inflammatory response in human corneal epithelium. PLoS One. 2013;8:e60963.
    • (2013) PLoS One , vol.8 , pp. 60963
    • Lin, J.1    Zhang, L.2    Zhao, G.3
  • 9
    • 33846101552 scopus 로고    scopus 로고
    • IL-33, the IL-1-like cytokine ligand for ST2 receptor, is a chromatin-associated nuclear factor in vivo
    • COI: 1:CAS:528:DC%2BD2sXjt12msw%3D%3D, PID: 17185418
    • Carriere V, Roussel L, Ortega N, et al. IL-33, the IL-1-like cytokine ligand for ST2 receptor, is a chromatin-associated nuclear factor in vivo. Proc Natl Acad Sci USA. 2007;104:282–7.
    • (2007) Proc Natl Acad Sci USA , vol.104 , pp. 282-287
    • Carriere, V.1    Roussel, L.2    Ortega, N.3
  • 10
    • 80051926552 scopus 로고    scopus 로고
    • The dual function cytokine IL-33 interacts with the transcription factor NF-κB to dampen NF-κB-stimulated gene transcription
    • COI: 1:CAS:528:DC%2BC3MXpslOrt70%3D, PID: 21734074
    • Ali S, Mohs A, Thomas M, et al. The dual function cytokine IL-33 interacts with the transcription factor NF-κB to dampen NF-κB-stimulated gene transcription. J Immunol. 2011;187:1609–16.
    • (2011) J Immunol. , vol.187 , pp. 1609-1616
    • Ali, S.1    Mohs, A.2    Thomas, M.3
  • 11
    • 77952324145 scopus 로고    scopus 로고
    • Epithelial-derived IL-33 and its receptor ST2 are dysregulated in ulcerative colitis and in experimental Th1/Th2 driven enteritis
    • COI: 1:CAS:528:DC%2BC3cXlsF2qu7c%3D, PID: 20385815
    • Pastorelli L, Garg RR, Hoang SB, et al. Epithelial-derived IL-33 and its receptor ST2 are dysregulated in ulcerative colitis and in experimental Th1/Th2 driven enteritis. Proc Natl Acad Sci USA. 2010;107:8017–22.
    • (2010) Proc Natl Acad Sci USA , vol.107 , pp. 8017-8022
    • Pastorelli, L.1    Garg, R.R.2    Hoang, S.B.3
  • 12
    • 78249249625 scopus 로고    scopus 로고
    • Interleukin-33 expression is specifically enhanced in inflamed mucosa of ulcerative colitis
    • COI: 1:CAS:528:DC%2BC3cXht1Omt7rP, PID: 20405148
    • Kobori A, Yagi Y, Imaeda H, et al. Interleukin-33 expression is specifically enhanced in inflamed mucosa of ulcerative colitis. J Gastroenterol. 2010;45:999–1007.
    • (2010) J Gastroenterol , vol.45 , pp. 999-1007
    • Kobori, A.1    Yagi, Y.2    Imaeda, H.3
  • 13
    • 79960982538 scopus 로고    scopus 로고
    • Acidic bile salts modulate the squamous epithelial barrier function by modulating tight junction proteins
    • COI: 1:CAS:528:DC%2BC3MXhtFSqurbO, PID: 21617116
    • Chen X, Oshima T, Tomita T, et al. Acidic bile salts modulate the squamous epithelial barrier function by modulating tight junction proteins. Am J Physiol Gastrointest Liver Physiol. 2011;301:G203–9.
    • (2011) Am J Physiol Gastrointest Liver Physiol , vol.301 , pp. 203-209
    • Chen, X.1    Oshima, T.2    Tomita, T.3
  • 14
    • 56549130616 scopus 로고    scopus 로고
    • Association of serum interleukin-33 level and the interleukin-33 genetic variant with Japanese cedar pollinosis
    • COI: 1:CAS:528:DC%2BD1MXnsV2qtQ%3D%3D, PID: 19037964
    • Sakashita M, Yoshimoto T, Hirota T, et al. Association of serum interleukin-33 level and the interleukin-33 genetic variant with Japanese cedar pollinosis. Clin Exp Allergy. 2008;38:1875–81.
    • (2008) Clin Exp Allergy , vol.38 , pp. 1875-1881
    • Sakashita, M.1    Yoshimoto, T.2    Hirota, T.3
  • 15
    • 79957660022 scopus 로고    scopus 로고
    • Establishment of esophageal-like non-keratinized stratified epithelium using normal human bronchial epithelial cells
    • COI: 1:CAS:528:DC%2BC3MXot1Cgurg%3D, PID: 21307344
    • Oshima T, Gedda K, Koseki J, et al. Establishment of esophageal-like non-keratinized stratified epithelium using normal human bronchial epithelial cells. Am J Physiol Cell Physiol. 2011;300:C1422–9.
    • (2011) Am J Physiol Cell Physiol , vol.300 , pp. 1422-1429
    • Oshima, T.1    Gedda, K.2    Koseki, J.3
  • 16
    • 84855215608 scopus 로고    scopus 로고
    • Acid modulates the squamous epithelial barrier function by modulating the localization of claudins in the superficial layers
    • COI: 1:CAS:528:DC%2BC38Xpt12n, PID: 21912379
    • Oshima T, Koseki J, Chen X, et al. Acid modulates the squamous epithelial barrier function by modulating the localization of claudins in the superficial layers. Lab Invest. 2012;92:22–31.
    • (2012) Lab Invest , vol.92 , pp. 22-31
    • Oshima, T.1    Koseki, J.2    Chen, X.3
  • 17
    • 70349572801 scopus 로고    scopus 로고
    • The role of interleukin-33 in chronic allergic conjunctivitis
    • PID: 19458329
    • Matsuda A, Okayama Y, Terai N, et al. The role of interleukin-33 in chronic allergic conjunctivitis. Invest Ophthalmol Vis Sci. 2009;50:4646–52.
    • (2009) Invest Ophthalmol Vis Sci , vol.50 , pp. 4646-4652
    • Matsuda, A.1    Okayama, Y.2    Terai, N.3
  • 18
    • 0036278756 scopus 로고    scopus 로고
    • Diversity in the oesophageal phenotypic response to gastro-oesophageal reflux: immunological determinants
    • COI: 1:STN:280:DC%2BD387ot1yrsQ%3D%3D, PID: 11889061
    • Fitzgerald RC, Onwuegbusi BA, Bajaj-Elliott M, et al. Diversity in the oesophageal phenotypic response to gastro-oesophageal reflux: immunological determinants. Gut. 2002;50:451–9.
    • (2002) Gut , vol.50 , pp. 451-459
    • Fitzgerald, R.C.1    Onwuegbusi, B.A.2    Bajaj-Elliott, M.3
  • 19
    • 77953323353 scopus 로고    scopus 로고
    • Rikkunshito, a traditional Japanese medicine, may relieve abdominal symptoms in rats with experimental esophagitis by improving the barrier function of epithelial cells in esophageal mucosa
    • PID: 20016992
    • Miwa H, Koseki J, Oshima T, et al. Rikkunshito, a traditional Japanese medicine, may relieve abdominal symptoms in rats with experimental esophagitis by improving the barrier function of epithelial cells in esophageal mucosa. J Gastroenterol. 2010;45:478–87.
    • (2010) J Gastroenterol , vol.45 , pp. 478-487
    • Miwa, H.1    Koseki, J.2    Oshima, T.3
  • 20
    • 79957994342 scopus 로고    scopus 로고
    • Role of E-cadherin in the pathogenesis of gastroesophageal reflux disease
    • COI: 1:CAS:528:DC%2BC3MXmvFyjtbk%3D, PID: 21448147
    • Jovov B, Que J, Tobey NA, et al. Role of E-cadherin in the pathogenesis of gastroesophageal reflux disease. Am J Gastroenterol. 2011;106:1039–47.
    • (2011) Am J Gastroenterol , vol.106 , pp. 1039-1047
    • Jovov, B.1    Que, J.2    Tobey, N.A.3
  • 21
    • 79958771491 scopus 로고    scopus 로고
    • Dissociation and dispersion of claudin-3 from the tight junction could be one of the most sensitive indicators of reflux esophagitis in a rat model of the disease
    • COI: 1:CAS:528:DC%2BC3MXlvFOjsL4%3D, PID: 21373849
    • Oguro M, Koike M, Ueno T, et al. Dissociation and dispersion of claudin-3 from the tight junction could be one of the most sensitive indicators of reflux esophagitis in a rat model of the disease. J Gastroenterol. 2011;46:629–38.
    • (2011) J Gastroenterol , vol.46 , pp. 629-638
    • Oguro, M.1    Koike, M.2    Ueno, T.3
  • 22
    • 84878112550 scopus 로고    scopus 로고
    • Esophageal intraluminal baseline impedance is associated with severity of acid reflux and epithelial structural abnormalities in patients with gastroesophageal reflux disease
    • COI: 1:CAS:528:DC%2BC3sXnvVKrtLg%3D, PID: 23076541
    • Zhong C, Duan L, Wang K, et al. Esophageal intraluminal baseline impedance is associated with severity of acid reflux and epithelial structural abnormalities in patients with gastroesophageal reflux disease. J Gastroenterol. 2013;48:601–10.
    • (2013) J Gastroenterol , vol.48 , pp. 601-610
    • Zhong, C.1    Duan, L.2    Wang, K.3
  • 23
    • 53749093767 scopus 로고    scopus 로고
    • The IL-1-like cytokine IL-33 is constitutively expressed in the nucleus of endothelial cells and epithelial cells in vivo: a novel ‘alarmin’?
    • PID: 18836528
    • Moussion C, Ortega N, Girard JP. The IL-1-like cytokine IL-33 is constitutively expressed in the nucleus of endothelial cells and epithelial cells in vivo: a novel ‘alarmin’? PLoS One. 2008;3:e3331.
    • (2008) PLoS One , vol.3 , pp. 3331
    • Moussion, C.1    Ortega, N.2    Girard, J.P.3
  • 24
    • 84863978673 scopus 로고    scopus 로고
    • Bile salts disrupt human esophageal squamous epithelial barrier function by modulating tight junction proteins
    • COI: 1:CAS:528:DC%2BC38Xht1OksrzM, PID: 22575221
    • Chen X, Oshima T, Shan J, et al. Bile salts disrupt human esophageal squamous epithelial barrier function by modulating tight junction proteins. Am J Physiol Gastrointest Liver Physiol. 2012;303:G199–208.
    • (2012) Am J Physiol Gastrointest Liver Physiol , vol.303 , pp. 199-208
    • Chen, X.1    Oshima, T.2    Shan, J.3
  • 25
    • 33846207542 scopus 로고    scopus 로고
    • Gastroesophageal reflux disease-associated esophagitis induces endogenous cytokine production leading to motor abnormalities
    • COI: 1:CAS:528:DC%2BD2sXit1aqsb4%3D, PID: 17241868
    • Rieder F, Cheng L, Harnett KM, et al. Gastroesophageal reflux disease-associated esophagitis induces endogenous cytokine production leading to motor abnormalities. Gastroenterology. 2007;132:154–65.
    • (2007) Gastroenterology , vol.132 , pp. 154-165
    • Rieder, F.1    Cheng, L.2    Harnett, K.M.3
  • 26
    • 84873191164 scopus 로고    scopus 로고
    • Evidence for a regulatory loop between IFN-γ and IL-33 in skin inflammation
    • COI: 1:CAS:528:DC%2BC3sXjsFGlt7s%3D, PID: 23362867
    • Seltmann J, Werfel T, Wittmann M. Evidence for a regulatory loop between IFN-γ and IL-33 in skin inflammation. Exp Dermatol. 2013;22:102–7.
    • (2013) Exp Dermatol , vol.22 , pp. 102-107
    • Seltmann, J.1    Werfel, T.2    Wittmann, M.3
  • 27
    • 84861830436 scopus 로고    scopus 로고
    • Regulation of interleukin-33 and thymic stromal lymphopoietin in human nasal fibroblasts by proinflammatory cytokines
    • COI: 1:CAS:528:DC%2BC38Xht1Sjtr%2FO, PID: 22460292
    • Nomura K, Kojima T, Fuchimoto J, et al. Regulation of interleukin-33 and thymic stromal lymphopoietin in human nasal fibroblasts by proinflammatory cytokines. Laryngoscope. 2012;122:1185–92.
    • (2012) Laryngoscope. , vol.122 , pp. 1185-1192
    • Nomura, K.1    Kojima, T.2    Fuchimoto, J.3
  • 28
    • 80054765055 scopus 로고    scopus 로고
    • Expression of IFN-γ and IL-4 in the esophageal mucosa of patients with reflux esophagitis and Barrett’s esophagus and their relationship with endoscopic and histologic grading
    • COI: 1:CAS:528:DC%2BC3MXht1ejsLfE, PID: 21479676
    • Zhong YQ, Lin Y, Xu Z. Expression of IFN-γ and IL-4 in the esophageal mucosa of patients with reflux esophagitis and Barrett’s esophagus and their relationship with endoscopic and histologic grading. Dig Dis Sci. 2011;56:2865–70.
    • (2011) Dig Dis Sci , vol.56 , pp. 2865-2870
    • Zhong, Y.Q.1    Lin, Y.2    Xu, Z.3
  • 29
    • 0032766497 scopus 로고    scopus 로고
    • Increased release of interleukin-6 by oesophageal mucosa in children with reflux oesophagitis
    • COI: 1:CAS:528:DC%2BD3cXhtV2htbo%3D, PID: 10514114
    • Corrado G, Zicari A, Cavaliere M, et al. Increased release of interleukin-6 by oesophageal mucosa in children with reflux oesophagitis. Eur J Gastroenterol Hepatol. 1999;11:839–43.
    • (1999) Eur J Gastroenterol Hepatol , vol.11 , pp. 839-843
    • Corrado, G.1    Zicari, A.2    Cavaliere, M.3
  • 30
    • 0037343905 scopus 로고    scopus 로고
    • Elevated levels of chemokines in esophageal mucosa of patients with reflux esophagitis
    • COI: 1:CAS:528:DC%2BD3sXjtVyltbo%3D, PID: 12650786
    • Isomoto H, Wang A, Mizuta Y, et al. Elevated levels of chemokines in esophageal mucosa of patients with reflux esophagitis. Am J Gastroenterol. 2003;98:551–6.
    • (2003) Am J Gastroenterol , vol.98 , pp. 551-556
    • Isomoto, H.1    Wang, A.2    Mizuta, Y.3
  • 31
    • 33847198229 scopus 로고    scopus 로고
    • Interleukin-8 levels in esophageal mucosa and long-term clinical outcome of patients with reflux esophagitis
    • PID: 17354124
    • Isomoto H, Inoue K, Kohno S. Interleukin-8 levels in esophageal mucosa and long-term clinical outcome of patients with reflux esophagitis. Scand J Gastroenterol. 2007;42:410–1.
    • (2007) Scand J Gastroenterol , vol.42 , pp. 410-411
    • Isomoto, H.1    Inoue, K.2    Kohno, S.3
  • 32
    • 0034960582 scopus 로고    scopus 로고
    • IL-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation
    • COI: 1:CAS:528:DC%2BD3MXkvFSltrY%3D, PID: 11420041
    • Hurst SM, Wilkinson TS, McLoughlin RM, et al. IL-6 and its soluble receptor orchestrate a temporal switch in the pattern of leukocyte recruitment seen during acute inflammation. Immunity. 2001;14:705–14.
    • (2001) Immunity , vol.14 , pp. 705-714
    • Hurst, S.M.1    Wilkinson, T.S.2    McLoughlin, R.M.3
  • 33
    • 36749026651 scopus 로고    scopus 로고
    • Interleukin (IL)-33 induces the release of pro-inflammatory mediators by mast cells
    • COI: 1:CAS:528:DC%2BD2sXhsVSmu7rE, PID: 18023358
    • Moulin D, Donze O, Talabot-Ayer D, et al. Interleukin (IL)-33 induces the release of pro-inflammatory mediators by mast cells. Cytokine. 2007;40:216–25.
    • (2007) Cytokine , vol.40 , pp. 216-225
    • Moulin, D.1    Donze, O.2    Talabot-Ayer, D.3
  • 34
    • 84887459057 scopus 로고    scopus 로고
    • Neutralisation of the interleukin-33/ST2 pathway ameliorates experimental colitis through enhancement of mucosal healing in mice
    • COI: 1:CAS:528:DC%2BC3sXhvFymt7%2FO, PID: 23172891
    • Sedhom MA, Pichery M, Murdoch JR, et al. Neutralisation of the interleukin-33/ST2 pathway ameliorates experimental colitis through enhancement of mucosal healing in mice. Gut. 2013;62:1714–23.
    • (2013) Gut , vol.62 , pp. 1714-1723
    • Sedhom, M.A.1    Pichery, M.2    Murdoch, J.R.3
  • 35
    • 34247135913 scopus 로고    scopus 로고
    • Classical nuclear localization signals: definition, function, and interaction with importin α
    • COI: 1:CAS:528:DC%2BD2sXhvVajs7k%3D, PID: 17170104
    • Lange A, Mills RE, Lange CJ, et al. Classical nuclear localization signals: definition, function, and interaction with importin α. J Biol Chem. 2007;282:5101–5.
    • (2007) J Biol Chem , vol.282 , pp. 5101-5105
    • Lange, A.1    Mills, R.E.2    Lange, C.J.3
  • 36
    • 45949111754 scopus 로고    scopus 로고
    • The IL-1 family member 7b translocates to the nucleus and down-regulates proinflammatory cytokines
    • COI: 1:CAS:528:DC%2BD1cXkt1artrk%3D, PID: 18390730
    • Sharma S, Kulk N, Nold MF, et al. The IL-1 family member 7b translocates to the nucleus and down-regulates proinflammatory cytokines. J Immunol. 2008;180:5477–82.
    • (2008) J Immunol. , vol.180 , pp. 5477-5482
    • Sharma, S.1    Kulk, N.2    Nold, M.F.3
  • 37
    • 84862872341 scopus 로고    scopus 로고
    • Transcriptional regulation of murine IL-33 by TLR and non-TLR agonists
    • COI: 1:CAS:528:DC%2BC38XovVyku7s%3D, PID: 22634618
    • Polumuri SK, Jayakar GG, Shirey KA, et al. Transcriptional regulation of murine IL-33 by TLR and non-TLR agonists. J Immunol. 2012;189:50–60.
    • (2012) J Immunol , vol.189 , pp. 50-60
    • Polumuri, S.K.1    Jayakar, G.G.2    Shirey, K.A.3
  • 38
    • 2942632783 scopus 로고    scopus 로고
    • IFN-γ activates cAMP/PKA/CREB signaling pathway in murine peritoneal macrophages
    • PID: 15212707
    • Liu L, Wang Y, Fan Y, et al. IFN-γ activates cAMP/PKA/CREB signaling pathway in murine peritoneal macrophages. J Interferon Cytokine Res. 2004;24:334–42.
    • (2004) J Interferon Cytokine Res , vol.24 , pp. 334-342
    • Liu, L.1    Wang, Y.2    Fan, Y.3


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