Electroacupuncture attenuates collagen-induced arthritis in rats through vasoactive intestinal peptide signalling-dependent re-establishment of the regulatory T cell/T-helper 17 cell balance

Acupuncture in Medicine

Volumn 33, Issue 4, 2015, Pages 305-311

  Zhu, Jun ^a   Chen, Xiao Yi ^a   Li, Lian Bo ^a   Yu, Xin Tong ^a   Zhou, Yin ^a   Yang, Wen Jia ^a   Liu, Zhen ^a   Zhao, Na ^a   Fu, Cong ^a   Zhang, Shu Hui ^a   Chen, Yun Fei ^a  

^a SHANGHAI UNIVERSITY OF TRADITIONAL CHINESE MEDICINE   (China)

Author keywords

[No Author keywords available]

Indexed keywords

COLLAGEN; VASOACTIVE INTESTINAL POLYPEPTIDE;

ANIMAL; ARTHRITIS, RHEUMATOID; CHEMICALLY INDUCED; ELECTROACUPUNCTURE; GENETICS; HUMAN; IMMUNOLOGY; MALE; RAT; REGULATORY T LYMPHOCYTE; SPRAGUE DAWLEY RAT; TH17 CELL;

ANIMALS; ARTHRITIS, RHEUMATOID; COLLAGEN; ELECTROACUPUNCTURE; HUMANS; MALE; RATS; RATS, SPRAGUE-DAWLEY; T-LYMPHOCYTES, REGULATORY; TH17 CELLS; VASOACTIVE INTESTINAL PEPTIDE;

EID: 84938600715     PISSN: 09645284     EISSN: 17599873     Source Type: Journal    
DOI: 10.1136/acupmed-2014-010732     Document Type: Article

References (24)

1. Firestein GS. Evolving concepts of rheumatoid arthritis. Nature 2003;423:356-61.
2. McInnes IB, Schett G. The pathogenesis of rheumatoid arthritis. N Engl J Med 2011;365:2205-19.
3. Li N, Wang JC, Liang TH, et al. Pathologic finding of increased expression of interleukin-17 in the synovial tissue of rheumatoid arthritis patients. Int J Clin Exp Pathol 2013;6:1375-9.
4. Wen T, Li Y, Wu M, et al. Therapeutic effects of a novel tylophorine analog, NK-007, on collagen-induced arthritis through suppressing tumor necrosis factor alpha production and Th17 cell differentiation. Arthritis Rheum 2012;64:2896-906.
5. Kelchtermans H, De Klerck B, Mitera T, et al. Defective CD4 +CD25+ regulatory T cell functioning in collagen-induced arthritis: an important factor in pathogenesis, counter-regulated by endogenous IFN-gamma. Arthritis Res Ther 2005;7: R402-15.
6. Nistala K, Wedderburn LR. Th17 and regulatory T cells: rebalancing pro-and anti-inflammatory forces in autoimmune arthritis. Rheumatology (Oxford) 2009;48:602-6.
7. Jimeno R, Leceta J, Martinez C, et al. Effect of VIP on the balance between cytokines and master regulators of activated helper T cells. Immunol Cell Biol 2012;90:178-86.
8. Deng S, Xi Y, Wang H, et al. Regulatory effect of vasoactive intestinal peptide on the balance of Treg and Th17 in collagen-induced arthritis. Cell Immunol 2010;265:105-10.
9. Juarranz Y, Gutierrez-Canas I, Santiago B, et al. Differential expression of vasoactive intestinal peptide and its functional receptors in human osteoarthritic and rheumatoid synovial fibroblasts. Arthritis Rheum 2008;58:1086-95.
10. Liu Y, Wang H, Wang X, et al. The mechanism of effective electroacupuncture on T cell response in rats with experimental autoimmune encephalomyelitis. PLoS ONE 2013;8:e51573.
11. Kwon Y, Sohn SH, Lee G, et al. Electroacupuncture attenuates ovalbumin-induced allergic asthma via modulating CD4(+) CD25(+) regulatory T cells. Evid Based Complement Alternat Med 2012;2012:647308.
12. Song JG, Li HH, Cao YF, et al. Electroacupuncture improves survival in rats with lethal endotoxemia via the autonomic nervous system. Anesthesiology 2012;116:406-14.
13. He TF, Yang WJ, Zhang SH, et al. Electroacupuncture inhibits inflammation reaction by upregulating vasoactive intestinal peptide in rats with adjuvant-induced arthritis. Evid Based Complement Alternat Med 2011;2011:290489.
14. Seo BK, Park DS, Baek YH. The analgesic effect of electroacupuncture on inflammatory pain in the rat model of collagenase-induced arthritis: mediation by opioidergic receptors. Rheumatol Int 2013;33:1177-83.
15. Ierna M, Kerr A, Scales H, et al. Supplementation of diet with krill oil protects against experimental rheumatoid arthritis. BMC Musculoskelet Disord 2010;11:136.
16. Tam LS, Leung PC, Li TK, et al. Acupuncture in the treatment of rheumatoid arthritis: a double-blind controlled pilot study. BMC Complement Altern Med 2007;7:35.
17. Torres-Rosas R, Yehia G, Peña G, et al. Dopamine mediates vagal modulation of the immune system by electroacupuncture. Nat Med 2014;20:291-5.
18. Baek YH, Choi DY, Yang HI, et al. Analgesic effect of electroacupuncture on inflammatory pain in the rat model of collagen-induced arthritis: mediation by cholinergic and serotonergic receptors. Brain Res 2005;1057:181-5.
19. Park DS, Seo BK, Baek YH. Analgesic effect of electroacupuncture on inflammatory pain in collagen-induced arthritis rats: mediation by alpha2-and beta-adrenoceptors. Rheumatol Int 2013;33:309-14.
20. Ouyang BS, Gao J, Che JL, et al. Effect of electro-acupuncture on tumor necrosis factor-alpha and vascular endothelial growth factor in peripheral blood and joint synovia of patients with rheumatoid arthritis. Chin J Integr Med 2011;17:505-9.
21. Delgado M, Robledo G, Rueda B, et al. Genetic association of vasoactive intestinal peptide receptor with rheumatoid arthritis: altered expression and signal in immune cells. Arthritis Rheum 2008;58:1010-19.
22. Gonzalez-Rey E, Varela N, Chorny A, et al. Therapeutical approaches of vasoactive intestinal peptide as a pleiotropic immunomodulator. Curr Pharm Des 2007;13:1113-39.
23. Delgado M, Toscano MG, Benabdellah K, et al. In vivo delivery of lentiviral vectors expressing vasoactive intestinal peptide complementary DNA as gene therapy for collagen-induced arthritis. Arthritis Rheum 2008;58:1026-37.
24. Chen G, Hao J, Xi Y, et al. The therapeutic effect of vasoactive intestinal peptide on experimental arthritis is associated with CD4+CD25+ Tregulatory cells. Scand J Immunol 2008;68:572-8.