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Volumn 16, Issue 8, 2015, Pages 750-759

Effects of Milnacipran on Clinical Pain and Hyperalgesia of Patients with Fibromyalgia: Results of a 6-Week Randomized Controlled Trial

Author keywords

clinical pain; clinical trial; Fibromyalgia; hyperalgesia; milnacipran; placebo

Indexed keywords

MILNACIPRAN; PLACEBO; CYCLOPROPANE DERIVATIVE; SEROTONIN UPTAKE INHIBITOR;

EID: 84938591665     PISSN: 15265900     EISSN: 15288447     Source Type: Journal    
DOI: 10.1016/j.jpain.2015.04.010     Document Type: Article
Times cited : (9)

References (53)
  • 1
    • 34250839388 scopus 로고    scopus 로고
    • Pathophysiological mechanisms in chronic musculoskeletal pain (fibromyalgia): The role of central and peripheral sensitization and pain disinhibition
    • L. Arendt-Nielsen, and K.G. Henriksson Pathophysiological mechanisms in chronic musculoskeletal pain (fibromyalgia): the role of central and peripheral sensitization and pain disinhibition Best Pract Res Clin Rheumatol 21 2007 465 480
    • (2007) Best Pract Res Clin Rheumatol , vol.21 , pp. 465-480
    • Arendt-Nielsen, L.1    Henriksson, K.G.2
  • 2
    • 0035430161 scopus 로고    scopus 로고
    • Pharmacologic treatment of fibromyalgia
    • A. Barkhuizen Pharmacologic treatment of fibromyalgia Curr Pain Headache Rep 5 2001 351 358
    • (2001) Curr Pain Headache Rep , vol.5 , pp. 351-358
    • Barkhuizen, A.1
  • 3
    • 84890761737 scopus 로고    scopus 로고
    • Peripheral input and its importance for central sensitization
    • R. Baron, G. Hans, and A.H. Dickenson Peripheral input and its importance for central sensitization Ann Neurol 74 2013 630 636
    • (2013) Ann Neurol , vol.74 , pp. 630-636
    • Baron, R.1    Hans, G.2    Dickenson, A.H.3
  • 4
    • 77950683671 scopus 로고    scopus 로고
    • A European multicenter randomized double-blind placebo-controlled monotherapy clinical trial of milnacipran in treatment of fibromyalgia
    • J.C. Branco, O. Zachrisson, S. Perrot, and Y. Mainguy A European multicenter randomized double-blind placebo-controlled monotherapy clinical trial of milnacipran in treatment of fibromyalgia J Rheumatol 37 2010 851 859
    • (2010) J Rheumatol , vol.37 , pp. 851-859
    • Branco, J.C.1    Zachrisson, O.2    Perrot, S.3    Mainguy, Y.4
  • 5
    • 0035131936 scopus 로고    scopus 로고
    • Are randomized clinical trials good for us (in the short term)? Evidence for a "trial effect"
    • D.A. Braunholtz, S.J. Edwards, and R.J. Lilford Are randomized clinical trials good for us (in the short term)? Evidence for a "trial effect" J Clin Epidemiol 54 2001 217 224
    • (2001) J Clin Epidemiol , vol.54 , pp. 217-224
    • Braunholtz, D.A.1    Edwards, S.J.2    Lilford, R.J.3
  • 6
    • 84898652844 scopus 로고    scopus 로고
    • Fibromyalgia: A clinical review
    • D.J. Clauw Fibromyalgia: A clinical review JAMA 311 2014 1547 1555
    • (2014) JAMA , vol.311 , pp. 1547-1555
    • Clauw, D.J.1
  • 7
    • 57649234533 scopus 로고    scopus 로고
    • Milnacipran for the treatment of fibromyalgia in adults: A 15-week, multicenter, randomized, double-blind, placebo-controlled, multiple-dose clinical trial
    • D.J. Clauw, P. Mease, R.H. Palmer, R.M. Gendreau, and Y. Wang Milnacipran for the treatment of fibromyalgia in adults: A 15-week, multicenter, randomized, double-blind, placebo-controlled, multiple-dose clinical trial Clin Ther 30 2008 1988 2004
    • (2008) Clin Ther , vol.30 , pp. 1988-2004
    • Clauw, D.J.1    Mease, P.2    Palmer, R.H.3    Gendreau, R.M.4    Wang, Y.5
  • 9
    • 84978714596 scopus 로고    scopus 로고
    • Available at: Ref Type: Statute
    • European Medicines Agency: European Medicines Agency Comment of Milnacipran. Available at: http://www.ema.europa.eu/docs/en-GB/document-library/Summary-of-opinion---Initial-authorisation/human/001034/WC500089875.pdf. 2014. Ref Type: Statute
    • (2014) European Medicines Agency Comment of Milnacipran
  • 10
    • 34250885099 scopus 로고    scopus 로고
    • Pharmacological treatment of fibromyalgia and other chronic musculoskeletal pain
    • D.L. Goldenberg Pharmacological treatment of fibromyalgia and other chronic musculoskeletal pain Best Pract Res Clin Rheumatol 21 2007 499 511
    • (2007) Best Pract Res Clin Rheumatol , vol.21 , pp. 499-511
    • Goldenberg, D.L.1
  • 12
    • 79953874953 scopus 로고    scopus 로고
    • Comparative efficacy and acceptability of amitriptyline, duloxetine and milnacipran in fibromyalgia syndrome: A systematic review with meta-analysis
    • W. Hauser, F. Petzke, N. Uceyler, and C. Sommer Comparative efficacy and acceptability of amitriptyline, duloxetine and milnacipran in fibromyalgia syndrome: A systematic review with meta-analysis Rheumatology 50 2010 532 543
    • (2010) Rheumatology , vol.50 , pp. 532-543
    • Hauser, W.1    Petzke, F.2    Uceyler, N.3    Sommer, C.4
  • 13
    • 84938615676 scopus 로고    scopus 로고
    • Available at:. Accessed June 24, 2015
    • IASP Taxonomy. Available at: http://www.iasp-pain.org/Taxonomy?navItemNumber=576#Hyperalgesia. Accessed June 24, 2015
  • 14
    • 33745238970 scopus 로고    scopus 로고
    • Differential blockade of nerve injury-induced shift in weight bearing and thermal and tactile hypersensitivity by milnacipran
    • T. King, S. Rao, T. Vanderah, Q. Chen, A. Vardanyan, and F. Porreca Differential blockade of nerve injury-induced shift in weight bearing and thermal and tactile hypersensitivity by milnacipran J Pain 7 2006 513 520
    • (2006) J Pain , vol.7 , pp. 513-520
    • King, T.1    Rao, S.2    Vanderah, T.3    Chen, Q.4    Vardanyan, A.5    Porreca, F.6
  • 15
    • 84973254011 scopus 로고    scopus 로고
    • The role of descending inhibitory pathways on chronic pain modulation and clinical implications
    • M. Kwon, M. Altin, H. Duenas, and L. Alev The role of descending inhibitory pathways on chronic pain modulation and clinical implications Pain Pract 20 2013 10
    • (2013) Pain Pract , vol.20 , pp. 10
    • Kwon, M.1    Altin, M.2    Duenas, H.3    Alev, L.4
  • 19
    • 64849117499 scopus 로고    scopus 로고
    • The efficacy and safety of milnacipran for treatment of fibromyalgia. A randomized, double-blind, placebo-controlled trial
    • P.J. Mease, D.J. Clauw, R.M. Gendreau, S.G. Rao, J. Kranzler, W. Chen, and R.H. Palmer the efficacy and safety of milnacipran for treatment of fibromyalgia. A randomized, double-blind, placebo-controlled trial J Rheumatol 36 2009 398 409
    • (2009) J Rheumatol , vol.36 , pp. 398-409
    • Mease, P.J.1    Clauw, D.J.2    Gendreau, R.M.3    Rao, S.G.4    Kranzler, J.5    Chen, W.6    Palmer, R.H.7
  • 21
    • 33847625893 scopus 로고    scopus 로고
    • Generalized deep-tissue hyperalgesia in patients with chronic low-back pain
    • S. O'Neill, C. Manniche, T. Graven-Nielsen, and L. Arendt-Nielsen Generalized deep-tissue hyperalgesia in patients with chronic low-back pain Eur J Pain 11 2007 415 420
    • (2007) Eur J Pain , vol.11 , pp. 415-420
    • O'Neill, S.1    Manniche, C.2    Graven-Nielsen, T.3    Arendt-Nielsen, L.4
  • 23
    • 0028012690 scopus 로고
    • A comparison of pain measurement characteristics of mechanical visual analogue and simple numerical rating scales
    • D.D. Price, F.M. Bush, S. Long, and S.W. Harkins A comparison of pain measurement characteristics of mechanical visual analogue and simple numerical rating scales Pain 56 1994 217 226
    • (1994) Pain , vol.56 , pp. 217-226
    • Price, D.D.1    Bush, F.M.2    Long, S.3    Harkins, S.W.4
  • 24
    • 0017739836 scopus 로고
    • Mechanisms of first and second pain in the peripheral and central nervous systems
    • D.D. Price, and R. Dubner Mechanisms of first and second pain in the peripheral and central nervous systems J Invest Dermatol 69 1977 167 171
    • (1977) J Invest Dermatol , vol.69 , pp. 167-171
    • Price, D.D.1    Dubner, R.2
  • 25
    • 0017358536 scopus 로고
    • Peripheral suppression of first pain and central summation of second pain evoked by noxious heat pulses
    • D.D. Price, J.W. Hu, R. Dubner, and R.H. Gracely Peripheral suppression of first pain and central summation of second pain evoked by noxious heat pulses Pain 3 1977 57 68
    • (1977) Pain , vol.3 , pp. 57-68
    • Price, D.D.1    Hu, J.W.2    Dubner, R.3    Gracely, R.H.4
  • 26
    • 70449633251 scopus 로고    scopus 로고
    • Critical role of nociceptor plasticity in chronic pain
    • D.B. Reichling, and J.D. Levine Critical role of nociceptor plasticity in chronic pain Trends Neurosci 32 2009 611 618
    • (2009) Trends Neurosci , vol.32 , pp. 611-618
    • Reichling, D.B.1    Levine, J.D.2
  • 29
    • 77954680188 scopus 로고    scopus 로고
    • Mechanisms of fibromyalgia pain
    • R. Staud Mechanisms of fibromyalgia pain CNS Spectr 14 2009 4 5
    • (2009) CNS Spectr , vol.14 , pp. 4-5
    • Staud, R.1
  • 30
    • 84896998141 scopus 로고    scopus 로고
    • The important role of CNS facilitation and inhibition for chronic pain
    • R. Staud The important role of CNS facilitation and inhibition for chronic pain Int J Clin Rheumtol 8 2013 639 646
    • (2013) Int J Clin Rheumtol , vol.8 , pp. 639-646
    • Staud, R.1
  • 31
    • 44149125707 scopus 로고    scopus 로고
    • Cutaneous C-fiber abnormalities of fibromyalgia patients are specifically related to temporal summation
    • R. Staud, C.E. Bovee, M.E. Robinson, and D.D. Price Cutaneous C-fiber abnormalities of fibromyalgia patients are specifically related to temporal summation Pain 139 2008 315 325
    • (2008) Pain , vol.139 , pp. 315-325
    • Staud, R.1    Bovee, C.E.2    Robinson, M.E.3    Price, D.D.4
  • 32
    • 0037333196 scopus 로고    scopus 로고
    • Temporal summation of pain from mechanical stimulation of muscle tissue in normal controls and subjects with fibromyalgia syndrome
    • R. Staud, R.C. Cannon, A.P. Mauderli, M.E. Robinson, D.D. Price, and C.J. Vierck Temporal summation of pain from mechanical stimulation of muscle tissue in normal controls and subjects with fibromyalgia syndrome Pain 102 2003 87 95
    • (2003) Pain , vol.102 , pp. 87-95
    • Staud, R.1    Cannon, R.C.2    Mauderli, A.P.3    Robinson, M.E.4    Price, D.D.5    Vierck, C.J.6
  • 33
    • 33746344360 scopus 로고    scopus 로고
    • Advanced continuous-contact heat pulse design for efficient temporal summation of second pain (wind-up)
    • R. Staud, D.D. Price, and R.B. Fillingim Advanced continuous-contact heat pulse design for efficient temporal summation of second pain (wind-up) J Pain 7 2006 575 582
    • (2006) J Pain , vol.7 , pp. 575-582
    • Staud, R.1    Price, D.D.2    Fillingim, R.B.3
  • 34
    • 75749124580 scopus 로고    scopus 로고
    • Do past pain events systematically impact pain ratings of healthy subjects or fibromyalgia patients?
    • R. Staud, M.E. Robinson, and D.D. Price Do past pain events systematically impact pain ratings of healthy subjects or fibromyalgia patients? J Pain 11 2010 142 148
    • (2010) J Pain , vol.11 , pp. 142-148
    • Staud, R.1    Robinson, M.E.2    Price, D.D.3
  • 35
    • 0141738725 scopus 로고    scopus 로고
    • Ratings of experimental pain and pain-related negative affect predict clinical pain in patients with fibromyalgia syndrome
    • R. Staud, M.E. Robinson, C.J. Vierck, R.L. Cannon, A.P. Mauderli, and D.D. Price Ratings of experimental pain and pain-related negative affect predict clinical pain in patients with fibromyalgia syndrome Pain 105 2003 215 222
    • (2003) Pain , vol.105 , pp. 215-222
    • Staud, R.1    Robinson, M.E.2    Vierck, C.J.3    Cannon, R.L.4    Mauderli, A.P.5    Price, D.D.6
  • 36
    • 77958109077 scopus 로고    scopus 로고
    • Pain variability in fibromyalgia is related to activity and rest: Role of peripheral tissue impulse input
    • R. Staud, M.E. Robinson, E.E. Weyl, and D.D. Price Pain variability in fibromyalgia is related to activity and rest: role of peripheral tissue impulse input J Pain 11 2010 1376 1383
    • (2010) J Pain , vol.11 , pp. 1376-1383
    • Staud, R.1    Robinson, M.E.2    Weyl, E.E.3    Price, D.D.4
  • 37
    • 84900003505 scopus 로고    scopus 로고
    • Analgesic and anti-hyperalgesic effects of muscle injections with lidocaine or saline in patients with fibromyalgia syndrome
    • R. Staud, E.E. Weyl, E. Bartley, D.D. Price, and M.E. Robinson Analgesic and anti-hyperalgesic effects of muscle injections with lidocaine or saline in patients with fibromyalgia syndrome Eur J Pain 18 2014 803 812
    • (2014) Eur J Pain , vol.18 , pp. 803-812
    • Staud, R.1    Weyl, E.E.2    Bartley, E.3    Price, D.D.4    Robinson, M.E.5
  • 38
    • 84864494991 scopus 로고    scopus 로고
    • Mechanical and heat hyperalgesia highly predict clinical pain intensity in patients with chronic musculoskeletal pain syndromes
    • R. Staud, E.E. Weyl, D.D. Price, and M.E. Robinson Mechanical and heat hyperalgesia highly predict clinical pain intensity in patients with chronic musculoskeletal pain syndromes J Pain 13 2012 725 735
    • (2012) J Pain , vol.13 , pp. 725-735
    • Staud, R.1    Weyl, E.E.2    Price, D.D.3    Robinson, M.E.4
  • 39
    • 84895860455 scopus 로고    scopus 로고
    • Slow temporal summation of pain for assessment of central pain sensitivity and clinical pain of fibromyalgia patients
    • R. Staud, E.E. Weyl, J.L. Riley III, and R.B. Fillingim Slow temporal summation of pain for assessment of central pain sensitivity and clinical pain of fibromyalgia patients PLoS One 9 2014 e89086
    • (2014) PLoS One , vol.9
    • Staud, R.1    Weyl, E.E.2    Riley, J.L.3    Fillingim, R.B.4
  • 40
  • 41
    • 0026586644 scopus 로고
    • Peripheral and central mechanisms of cutaneous hyperalgesia
    • R.D. Treede, R.A. Meyer, S.N. Raja, and J.N. Campbell Peripheral and central mechanisms of cutaneous hyperalgesia Prog Neurobiol 38 1992 397 421
    • (1992) Prog Neurobiol , vol.38 , pp. 397-421
    • Treede, R.D.1    Meyer, R.A.2    Raja, S.N.3    Campbell, J.N.4
  • 43
    • 57749193097 scopus 로고    scopus 로고
    • Antidepressants for the treatment of chronic pain
    • B. Verdu, I. Decosterd, T. Buclin, F. Stiefel, and A. Berney Antidepressants for the treatment of chronic pain Drugs 68 2008 2611 2632
    • (2008) Drugs , vol.68 , pp. 2611-2632
    • Verdu, B.1    Decosterd, I.2    Buclin, T.3    Stiefel, F.4    Berney, A.5
  • 44
    • 0034983148 scopus 로고    scopus 로고
    • Hypersensitivity to visceral and cutaneous pain in the irritable bowel syndrome
    • G.N. Verne, M.E. Robinson, and D.D. Price Hypersensitivity to visceral and cutaneous pain in the irritable bowel syndrome Pain 93 2001 7 14
    • (2001) Pain , vol.93 , pp. 7-14
    • Verne, G.N.1    Robinson, M.E.2    Price, D.D.3
  • 45
    • 0030275440 scopus 로고    scopus 로고
    • Assessing the stages of pain processing: A multivariate analytical approach
    • J.B. Wade, L.M. Dougherty, C.R. Archer, and D.D. Price Assessing the stages of pain processing: A multivariate analytical approach Pain 68 1996 157 167
    • (1996) Pain , vol.68 , pp. 157-167
    • Wade, J.B.1    Dougherty, L.M.2    Archer, C.R.3    Price, D.D.4
  • 47
    • 0021014399 scopus 로고
    • Evidence for a central component of post-injury pain hypersensitivity
    • C.J. Woolf Evidence for a central component of post-injury pain hypersensitivity Nature 306 1983 686 688
    • (1983) Nature , vol.306 , pp. 686-688
    • Woolf, C.J.1
  • 48
    • 0029551020 scopus 로고
    • An overview of the mechanisms of hyperalgesia
    • C.J. Woolf An overview of the mechanisms of hyperalgesia Pulm Pharmacol 8 1995 161 167
    • (1995) Pulm Pharmacol , vol.8 , pp. 161-167
    • Woolf, C.J.1
  • 49
    • 79951579664 scopus 로고    scopus 로고
    • Central sensitization: Implications for the diagnosis and treatment of pain
    • C.J. Woolf Central sensitization: Implications for the diagnosis and treatment of pain Pain 152 2011 S2 S15
    • (2011) Pain , vol.152 , pp. S2-S15
    • Woolf, C.J.1
  • 50
    • 84896399063 scopus 로고    scopus 로고
    • Pain modulation profile and pain therapy: Between pro- and antinociception
    • D. Yarnitsky, M. Granot, and Y. Granovsky Pain modulation profile and pain therapy: Between pro- and antinociception Pain 155 2014 663 665
    • (2014) Pain , vol.155 , pp. 663-665
    • Yarnitsky, D.1    Granot, M.2    Granovsky, Y.3
  • 51
    • 84861186602 scopus 로고    scopus 로고
    • Conditioned pain modulation predicts duloxetine efficacy in painful diabetic neuropathy
    • D. Yarnitsky, M. Granot, H. Nahman-Averbuch, M. Khamaisi, and Y. Granovsky Conditioned pain modulation predicts duloxetine efficacy in painful diabetic neuropathy Pain 153 2012 1193 1198
    • (2012) Pain , vol.153 , pp. 1193-1198
    • Yarnitsky, D.1    Granot, M.2    Nahman-Averbuch, H.3    Khamaisi, M.4    Granovsky, Y.5
  • 52
    • 0026771257 scopus 로고
    • Single C nociceptor responses and psychophysical parameters of evoked pain: Effect of rate of rise of heat stimuli in humans
    • D. Yarnitsky, D.A. Simone, R.M. Dotson, M.A. Cline, and J.L. Ochoa Single C nociceptor responses and psychophysical parameters of evoked pain: Effect of rate of rise of heat stimuli in humans J Physiol 450 1992 581 592
    • (1992) J Physiol , vol.450 , pp. 581-592
    • Yarnitsky, D.1    Simone, D.A.2    Dotson, R.M.3    Cline, M.A.4    Ochoa, J.L.5
  • 53
    • 0030276412 scopus 로고    scopus 로고
    • Nociceptive responses to high and low rates of noxious cutaneous heating are mediated by different nociceptors in the rat: Electrophysiological evidence
    • D.C. Yeomans, and H.K. Proudfit Nociceptive responses to high and low rates of noxious cutaneous heating are mediated by different nociceptors in the rat: electrophysiological evidence Pain 68 1996 141 150
    • (1996) Pain , vol.68 , pp. 141-150
    • Yeomans, D.C.1    Proudfit, H.K.2


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