Associations of menstrual cycle irregularities with age, obesity and phenotype in patients with polycystic ovary syndrome

Hormones

Volumn 14, Issue 3, 2015, Pages 431-437

  Panidis, Dimitrios ^a   Tziomalos, Konstantinos ^a   Papadakis, Efstathios ^a   Chatzis, Panagiotis ^a   Kandaraki, Eleni A ^a   Tsourdi, Elena A ^a   Macut, Djuro ^b   Bjekic Macut, Jelica ^b   Marthopoulos, Apostolos ^a   Katsikis, Ilias ^a  

^a ARISTOTLE UNIVERSITY OF THESSALONIKI   (Greece)

^b UNIVERSITY OF BELGRADE   (Serbia)

Author keywords

Age; Androgens; Insulin resistance; Menstrual cycle; Obesity; Phenotype; Polycystic ovary syndrome

Indexed keywords

ABDOMINAL OBESITY; ADULT; AGE; ANOVULATION; ARTICLE; BODY MASS; CONTROLLED STUDY; DISEASE ASSOCIATION; FEMALE; HUMAN; HYPERANDROGENISM; MAJOR CLINICAL STUDY; MENSTRUAL IRREGULARITY; OBESITY; OVARY POLYCYSTIC DISEASE; PHENOTYPE; PREVALENCE; CLASSIFICATION; COMORBIDITY; MENSTRUATION DISTURBANCES; POLYCYSTIC OVARY SYNDROME; YOUNG ADULT;

ADULT; AGE FACTORS; COMORBIDITY; FEMALE; HUMANS; MENSTRUATION DISTURBANCES; OBESITY; PHENOTYPE; POLYCYSTIC OVARY SYNDROME; YOUNG ADULT;

EID: 84938529955     PISSN: 11093099     EISSN: 25208721     Source Type: Journal    
DOI: 10.14310/horm.2002.1593     Document Type: Article

References (32)

1. Goodarzi MO, Dumesic DA, Chazenbalk G, Azziz R, 2011 Polycystic ovary syndrome: etiology, pathogenesis and diagnosis. Nat Rev Endocrinol 7: 219-231.
2. Rotterdam ESHRE/ASRM-Sponsored PCOS Consensus Workshop Group, 2004 Revised 2003 consensus on diagnostic criteria and long-term health risks related to polycystic ovary syndrome (PCOS). Hum Reprod 19: 41-47.
3. Dahlgren E, Johansson S, Lindstedt G, et al, 1992 Women with polycystic ovary syndrome wedge resected in 1956 to 1965: a long-term follow-up focusing on natural history and circulating hormones. Fertil Steril 57: 505-513.
4. Elting MW, Korsen TJ, Rekers-Mombarg LT, Schoemaker J, 2000 Women with polycystic ovary syndrome gain regular menstrual cycles when ageing. Hum Reprod 15: 24-28.
5. Brown ZA, Louwers YV, Fong SL, et al, 2011 The phenotype of polycystic ovary syndrome ameliorates with aging. Fertil Steril 96: 1259-1265.
6. Hartz AJ, Barboriak PN, Wong A, Katayama KP, Rimm AA, 1979 The association of obesity with infertility and related menstural abnormalities in women. Int J Obes 3: 57-73.
7. Hartz AJ, Rupley DC, Rimm AA, 1984 The association of girth measurements with disease in 32,856 women. Am J Epidemiol 119: 71-80.
8. Rowland AS, Baird DD, Long S, et al, 2002 Influence of medical conditions and lifestyle factors on the menstrual cycle. Epidemiology 13: 668-674.
9. Kiddy DS, Sharp PS, White DM, et al, 1990 Differences in clinical and endocrine features between obese and non-obese subjects with polycystic ovary syndrome: an analysis of 263 consecutive cases. Clin Endocrinol (Oxf) 32: 213-220.
10. Balen AH, Conway GS, Kaltsas G, et al, 1995 Polycystic ovary syndrome: the spectrum of the disorder in 1741 patients. Hum Reprod 10: 2107-2111.
11. Cupisti S, Kajaia N, Dittrich R, Duezenli H, Beckmann MW, Mueller A, 2008 Body mass index and ovarian function are associated with endocrine and metabolic abnormalities in women with hyperandrogenic syndrome. Eur J Endocrinol 158: 711-719.
12. Strowitzki T, Capp E, von Eye Corleta H, 2010 The degree of cycle irregularity correlates with the grade of endocrine and metabolic disorders in PCOS patients. Eur J Obstet Gynecol Reprod Biol 149: 178-181.
13. Panidis D, Tziomalos K, Chatzis P, et al, 2013 Association between menstrual cycle irregularities and endocrine and metabolic characteristics of the polycystic ovary syndrome. Eur J Endocrinol 168: 145-152.
14. Piouka A, Farmakiotis D, Katsikis I, Macut D, Gerou S, Panidis D, 2009 Anti-Müllerian hormone levels reflect severity of PCOS but are negatively influenced by obesity: relationship with increased luteinizing hormone levels. Am J Physiol Endocrinol Metab 296: E238-243.
15. Carter GD, Holland SM, Alaghband-Zadeh J, Rayman G, Dorrington-Ward P, Wise PH, 1983 Investigation of hirsutism: testosterone is not enough. Ann Clin Biochem 20: 262-263.
16. Matthews D, Hosker J, Rudenski A, Naylor B, Treacher D, Turner R, 1985 Homeostasis model assessment: insulin resistance and beta-cell function from fasting plasma glucose and insulin concentrations in man. Diabetologia 28: 12-19.
17. Katz A, Nambi SS, Mather K, et al, 2000 Quantitative insulin sensitivity check index: a simple, accurate method for assessing insulin sensitivity in humans. J Clin Endocrinol Metab 85: 2402-2410.
18. Kumar A, Woods KS, Bartolucci AA, Azziz R, 2005 Prevalence of adrenal androgen excess in patients with the polycystic ovary syndrome (PCOS). Clin Endocrinol (Oxf) 62: 644-649.
19. Carmina E, Campagna AM, Lobo RA, 2012 A 20-year follow-up of young women with polycystic ovary syndrome. Obstet Gynecol 119: 263-269.
20. Panidis D, Tziomalos K, Macut D, et al, 2012 Crosssectional analysis of the effects of age on the hormonal, metabolic, and ultrasonographic features and the prevalence of the different phenotypes of polycystic ovary syndrome. Fertil Steril 97: 494-500.
21. Kiddy DS, Hamilton-Fairley D, Bush A, et al, 1992 Improvement in endocrine and ovarian function during dietary treatment of obese women with polycystic ovary syndrome. Clin Endocrinol (Oxf) 36: 105-111.
22. Huber-Buchholz MM, Carey DG, Norman RJ, 1999 Restoration of reproductive potential by lifestyle modification in obese polycystic ovary syndrome: role of insulin sensitivity and luteinizing hormone. J Clin Endocrinol Metab 84: 1470-1474.
23. Crosignani PG, Colombo M, Vegetti W, Somigliana E, Gessati A, Ragni G, 2003 Overweight and obese anovulatory patients with polycystic ovaries: parallel improvements in anthropometric indices, ovarian physiology and fertility rate induced by diet. Hum Reprod 18: 1928-1932.
24. Holte J, Bergh T, Gennarelli G, Wide L, 1994 The independent effects of polycystic ovary syndrome and obesity on serum concentrations of gonadotrophins and sex steroids in premenopausal women. Clin Endocrinol (Oxf) 41: 473-481.
25. Morales AJ, Laughlin GA, Bützow T, Maheshwari H, Baumann G, Yen SS, 1996 Insulin, somatotropic, and luteinizing hormone axes in lean and obese women with polycystic ovary syndrome: common and distinct features. J Clin Endocrinol Metab 81: 2854-2864.
26. Morin-Papunen LC, Vauhkonen I, Koivunen RM, Ruokonen A, Tapanainen JS, 2000 Insulin sensitivity, insulin secretion, and metabolic and hormonal parameters in healthy women and women with polycystic ovarian syndrome. Hum Reprod 15: 1266-1274.
27. Loucks TL, Talbott EO, McHugh KP, Keelan M, Berga SL, Guzick DS, 2000 Do polycystic-appearing ovaries affect the risk of cardiovascular disease among women with polycystic ovary syndrome? Fertil Steril 74: 547-552.
28. Hahn S, Bering van Halteren W, Roesler S, et al, 2006 The combination of increased ovarian volume and follicle number is associated with more severe hyperandrogenism in German women with polycystic ovary syndrome. Exp Clin Endocrinol Diabetes 114: 175-181.
29. Panidis D, Tziomalos K, Misichronis G, et al, 2012 Insulin resistance and endocrine characteristics of the different phenotypes of polycystic ovary syndrome: a prospective study. Hum Reprod 27: 541-549.
30. Solomon CG, Hu FB, Dunaif A, et al, 2001 Long or highly irregular menstrual cycles as a marker for risk of type 2 diabetes mellitus. JAMA 286: 2421-2426.
31. Solomon CG, Hu FB, Dunaif A, et al, 2002 Menstrual cycle irregularity and risk for future cardiovascular disease. J Clin Endocrinol Metab 87: 2013-2017.
32. Dilbaz B, Ozkaya E, Cinar M, Cakir E, Dilbaz S, 2011 Cardiovascular disease risk characteristics of the main polycystic ovary syndrome phenotypes. Endocrine 39: 272-277.