메뉴 건너뛰기




Volumn 50, Issue 3, 2015, Pages 334-340

A review of the genetic and long-term effects of G-CSF injections in healthy donors: A reassuring lack of evidence for the development of haematological malignancies

Author keywords

[No Author keywords available]

Indexed keywords

GRANULOCYTE COLONY STIMULATING FACTOR;

EID: 84938419338     PISSN: 02683369     EISSN: 14765365     Source Type: Journal    
DOI: 10.1038/bmt.2014.278     Document Type: Review
Times cited : (51)

References (42)
  • 1
    • 84902084387 scopus 로고    scopus 로고
    • Hematopoietic SCT in Europe: Data and trends in 2012 with special consideration of pediatric transplantation
    • Passweg JR, Baldomero H, Peters C, Gaspar HB, Cesaro S, Dreger P et al. Hematopoietic SCT in Europe: data and trends in 2012 with special consideration of pediatric transplantation. Bone Marrow Transplant 2014; 49: 744-750.
    • (2014) Bone Marrow Transplant , vol.49 , pp. 744-750
    • Passweg, J.R.1    Baldomero, H.2    Peters, C.3    Gaspar, H.B.4    Cesaro, S.5    Dreger, P.6
  • 2
    • 0028131845 scopus 로고
    • Granulocyte colony-stimulating factor administration to healthy volunteers: Analysis of the immediate activating effects on circulating neutrophils
    • de Haas M, Kerst JM, van der Schoot CE, Calafat J, Hack CE, Nuijens JH et al. Granulocyte colony-stimulating factor administration to healthy volunteers: analysis of the immediate activating effects on circulating neutrophils. Blood 1994; 84: 3885-3894.
    • (1994) Blood , vol.84 , pp. 3885-3894
    • De Haas, M.1    Kerst, J.M.2    Van Der Schoot, C.E.3    Calafat, J.4    Hack, C.E.5    Nuijens, J.H.6
  • 3
    • 41349110208 scopus 로고    scopus 로고
    • Biologic and molecular effects of granulocyte colonystimulating factor in healthy individuals: Recent findings and current challenges
    • Anderlini P, Champlin RE. Biologic and molecular effects of granulocyte colonystimulating factor in healthy individuals: recent findings and current challenges. Blood 2008; 111: 1767-1772.
    • (2008) Blood , vol.111 , pp. 1767-1772
    • Anderlini, P.1    Champlin, R.E.2
  • 4
    • 33750547396 scopus 로고    scopus 로고
    • Haematological malignancies developing in previously healthy individuals who received haematopoietic growth factors: Report from the Research on Adverse Drug Events and Reports (RADAR) project
    • Bennett CL, Evens AM, Andritsos LA, Balasubramanian L, Mai M, Fisher MJ et al. Haematological malignancies developing in previously healthy individuals who received haematopoietic growth factors: report from the Research on Adverse Drug Events and Reports (RADAR) project. Br J Haematol 2006; 135: 642-650.
    • (2006) Br J Haematol , vol.135 , pp. 642-650
    • Bennett, C.L.1    Evens, A.M.2    Andritsos, L.A.3    Balasubramanian, L.4    Mai, M.5    Fisher, M.J.6
  • 5
    • 0347569519 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor generates epigenetic and genetic alterations in lymphocytes of normal volunteer donors of stem cells
    • Nagler A, Korenstein-Ilan A, Amiel A, Avivi L. Granulocyte colony-stimulating factor generates epigenetic and genetic alterations in lymphocytes of normal volunteer donors of stem cells. Exp Hematol 2004; 32: 122-130.
    • (2004) Exp Hematol , vol.32 , pp. 122-130
    • Nagler, A.1    Korenstein-Ilan, A.2    Amiel, A.3    Avivi, L.4
  • 6
    • 33750542738 scopus 로고    scopus 로고
    • The use of granulocyte colony-stimulating factor in volunteer blood and marrow registry donors
    • Pamphilon D, Mackinnon S, Nacheva E, Russell N, Wilson K, Clay M et al. The use of granulocyte colony-stimulating factor in volunteer blood and marrow registry donors. Bone Marrow Transplant 2006; 38: 699-700.
    • (2006) Bone Marrow Transplant , vol.38 , pp. 699-700
    • Pamphilon, D.1    Mackinnon, S.2    Nacheva, E.3    Russell, N.4    Wilson, K.5    Clay, M.6
  • 7
    • 33745096897 scopus 로고    scopus 로고
    • The incidence of leukemia and mortality from sepsis in patients with severe congenital neutropenia receiving long-term G-CSF therapy
    • Rosenberg PS, Alter BP, Bolyard AA, Bonilla MA, Boxer LA, Cham B et al. The incidence of leukemia and mortality from sepsis in patients with severe congenital neutropenia receiving long-term G-CSF therapy. Blood 2006; 107: 4628-4635.
    • (2006) Blood , vol.107 , pp. 4628-4635
    • Rosenberg, P.S.1    Alter, B.P.2    Bolyard, A.A.3    Bonilla, M.A.4    Boxer, L.A.5    Cham, B.6
  • 8
    • 66049129912 scopus 로고    scopus 로고
    • Hematopoietic growth factors in aplastic anemia patients treated with immunosuppressive therapy-systematic review and meta-analysis
    • Gurion R, Gafter-Gvili A, Paul M, Vidal L, Ben-Bassat I, Yeshurun M et al. Hematopoietic growth factors in aplastic anemia patients treated with immunosuppressive therapy-systematic review and meta-analysis. Haematologica 2009; 94: 712-719.
    • (2009) Haematologica , vol.94 , pp. 712-719
    • Gurion, R.1    Gafter-Gvili, A.2    Paul, M.3    Vidal, L.4    Ben-Bassat, I.5    Yeshurun, M.6
  • 9
    • 19944430855 scopus 로고    scopus 로고
    • Analysis of risk factors for myelodysplasias, leukemias and death from infection among patients with congenital neutropenia. Experience of the French Severe Chronic Neutropenia Study Group
    • Donadieu J, Leblanc T, Bader Meunier B, Barkaoui M, Fenneteau O, Bertrand Y et al. Analysis of risk factors for myelodysplasias, leukemias and death from infection among patients with congenital neutropenia. Experience of the French Severe Chronic Neutropenia Study Group. Haematologica 2005; 90: 45-53.
    • (2005) Haematologica , vol.90 , pp. 45-53
    • Donadieu, J.1    Leblanc, T.2    Bader Meunier, B.3    Barkaoui, M.4    Fenneteau, O.5    Bertrand, Y.6
  • 10
    • 33947594348 scopus 로고    scopus 로고
    • Granulocyte-stimulating factor and severe aplastic anemia: A survey by the European Group for Blood and Marrow Transplantation (EBMT)
    • Socie G, Mary JY, Schrezenmeier H, Marsh J, Bacigalupo A, Locasciulli A et al. Granulocyte-stimulating factor and severe aplastic anemia: a survey by the European Group for Blood and Marrow Transplantation (EBMT). Blood 2007; 109: 2794-2796.
    • (2007) Blood , vol.109 , pp. 2794-2796
    • Socie, G.1    Mary, J.Y.2    Schrezenmeier, H.3    Marsh, J.4    Bacigalupo, A.5    Locasciulli, A.6
  • 11
    • 0036682934 scopus 로고    scopus 로고
    • Risk factors for evolution of acquired aplastic anemia into myelodysplastic syndrome and acute myeloid leukemia after immunosuppressive therapy in children
    • Kojima S, Ohara A, Tsuchida M, Kudoh T, Hanada R, Okimoto Y et al. Risk factors for evolution of acquired aplastic anemia into myelodysplastic syndrome and acute myeloid leukemia after immunosuppressive therapy in children. Blood 2002; 100: 786-790.
    • (2002) Blood , vol.100 , pp. 786-790
    • Kojima, S.1    Ohara, A.2    Tsuchida, M.3    Kudoh, T.4    Hanada, R.5    Okimoto, Y.6
  • 12
    • 33947233757 scopus 로고    scopus 로고
    • Long-term safety of filgrastim (rhG-CSF) administration
    • author reply 79-80
    • Confer DL, Miller JP. Long-term safety of filgrastim (rhG-CSF) administration. Br J Haematol 2007; 137: 77-78 author reply 79-80.
    • (2007) Br J Haematol , vol.137 , pp. 77-78
    • Confer, D.L.1    Miller, J.P.2
  • 13
    • 33750572666 scopus 로고    scopus 로고
    • Possible harmful effects of short course granulocyte colony-stimulating factor in normal donors
    • Goldman JM, Madrigal JA, Pamphilon D. Possible harmful effects of short course granulocyte colony-stimulating factor in normal donors. Br J Haematol 2006; 135: 651-652.
    • (2006) Br J Haematol , vol.135 , pp. 651-652
    • Goldman, J.M.1    Madrigal, J.A.2    Pamphilon, D.3
  • 14
    • 65349145905 scopus 로고    scopus 로고
    • Adverse events among 2408 unrelated donors of peripheral blood stem cells: Results of a prospective trial from the National Marrow Donor Program
    • Pulsipher MA, Chitphakdithai P, Miller JP, Logan BR, King RJ, Rizzo JD et al. Adverse events among 2408 unrelated donors of peripheral blood stem cells: results of a prospective trial from the National Marrow Donor Program. Blood 2009; 113: 3604-3611.
    • (2009) Blood , vol.113 , pp. 3604-3611
    • Pulsipher, M.A.1    Chitphakdithai, P.2    Miller, J.P.3    Logan, B.R.4    King, R.J.5    Rizzo, J.D.6
  • 15
    • 84872059501 scopus 로고    scopus 로고
    • Acute toxicities of unrelated bone marrow versus peripheral blood stem cell donation: Results of a prospective trial from the National Marrow Donor Program
    • Pulsipher MA, Chitphakdithai P, Logan BR, Shaw BE, Wingard JR, Lazarus HM et al. Acute toxicities of unrelated bone marrow versus peripheral blood stem cell donation: results of a prospective trial from the National Marrow Donor Program. Blood 2013; 121: 197-206.
    • (2013) Blood , vol.121 , pp. 197-206
    • Pulsipher, M.A.1    Chitphakdithai, P.2    Logan, B.R.3    Shaw, B.E.4    Wingard, J.R.5    Lazarus, H.M.6
  • 18
    • 70449717293 scopus 로고    scopus 로고
    • Safety and efficacy of hematopoietic stem cell collection from mobilized peripheral blood in unrelated volunteers: 12 years of single-center experience in 3928 donors
    • Holig K, Kramer M, Kroschinsky F, Bornhauser M, Mengling T, Schmidt AH et al. Safety and efficacy of hematopoietic stem cell collection from mobilized peripheral blood in unrelated volunteers: 12 years of single-center experience in 3928 donors. Blood 2009; 114: 3757-3763.
    • (2009) Blood , vol.114 , pp. 3757-3763
    • Holig, K.1    Kramer, M.2    Kroschinsky, F.3    Bornhauser, M.4    Mengling, T.5    Schmidt, A.H.6
  • 20
    • 0034194041 scopus 로고    scopus 로고
    • Normal T B, and NK cell counts in healthy donors at 1 year after blood stem cell harvesting
    • Storek J, Dawson MA, Maloney DG. Normal T, B, and NK cell counts in healthy donors at 1 year after blood stem cell harvesting. Blood 2000; 95: 2993-2994.
    • (2000) Blood , vol.95 , pp. 2993-2994
    • Storek, J.1    Dawson, M.A.2    Maloney, D.G.3
  • 21
    • 78650011517 scopus 로고    scopus 로고
    • Persistence of lymphocyte function perturbations after granulocyte-colonystimulating factor mobilization and cytapheresis in normal peripheral blood stem cell donors
    • Marmier-Savet C, Larosa F, Legrand F, Witz B, Michallet M, Ranta D et al. Persistence of lymphocyte function perturbations after granulocyte-colonystimulating factor mobilization and cytapheresis in normal peripheral blood stem cell donors. Transfusion 2010; 50: 2676-2685.
    • (2010) Transfusion , vol.50 , pp. 2676-2685
    • Marmier-Savet, C.1    Larosa, F.2    Legrand, F.3    Witz, B.4    Michallet, M.5    Ranta, D.6
  • 22
    • 0033979660 scopus 로고    scopus 로고
    • Three to six year follow-up of normal donors who received recombinant human granulocyte colony-stimulating factor
    • Cavallaro AM, Lilleby K, Majolino I, Storb R, Appelbaum FR, Rowley SD et al. Three to six year follow-up of normal donors who received recombinant human granulocyte colony-stimulating factor. Bone Marrow Transplant 2000; 25: 85-89.
    • (2000) Bone Marrow Transplant , vol.25 , pp. 85-89
    • Cavallaro, A.M.1    Lilleby, K.2    Majolino, I.3    Storb, R.4    Appelbaum, F.R.5    Rowley, S.D.6
  • 23
    • 23944468556 scopus 로고    scopus 로고
    • Short- and long-term haematological surveillance of healthy donors of allogeneic peripheral haematopoietic progenitors mobilized with G-CSF: A single institution prospective study
    • Tassi C, Tazzari PL, Bonifazi F, Giudice V, Nannetti A, Ricci F et al. Short- and long-term haematological surveillance of healthy donors of allogeneic peripheral haematopoietic progenitors mobilized with G-CSF: a single institution prospective study. Bone Marrow Transplant 2005; 36: 289-294.
    • (2005) Bone Marrow Transplant , vol.36 , pp. 289-294
    • Tassi, C.1    Tazzari, P.L.2    Bonifazi, F.3    Giudice, V.4    Nannetti, A.5    Ricci, F.6
  • 24
    • 60149086306 scopus 로고    scopus 로고
    • Ten-year follow-up of unrelated volunteer granulocyte donors who have received multiple cycles of granulocyte-colonystimulating factor and dexamethasone
    • Quillen K, Byrne P, Yau YY, Leitman SF. Ten-year follow-up of unrelated volunteer granulocyte donors who have received multiple cycles of granulocyte-colonystimulating factor and dexamethasone. Transfusion 2009; 49: 513-518.
    • (2009) Transfusion , vol.49 , pp. 513-518
    • Quillen, K.1    Byrne, P.2    Yau, Y.Y.3    Leitman, S.F.4
  • 26
    • 0037404719 scopus 로고    scopus 로고
    • Granulocyte colony stimulating factor does not induce long-term DNA instability in healthy peripheral blood stem cell donors
    • Shapira MY, Kaspler P, Samuel S, Shoshan S, Or R. Granulocyte colony stimulating factor does not induce long-term DNA instability in healthy peripheral blood stem cell donors. Am J Hematol 2003; 73: 33-36.
    • (2003) Am J Hematol , vol.73 , pp. 33-36
    • Shapira, M.Y.1    Kaspler, P.2    Samuel, S.3    Shoshan, S.4    Or, R.5
  • 27
    • 80052415559 scopus 로고    scopus 로고
    • Effects of granulocyte-colony stimulating factor on chromosome aneuploidy and replication asynchrony in healthy peripheral blood stem cell donors
    • Hirsch B, Oseth L, Cain M, Trader E, Pulkrabek S, Lindgren B et al. Effects of granulocyte-colony stimulating factor on chromosome aneuploidy and replication asynchrony in healthy peripheral blood stem cell donors. Blood 2011; 118: 2602-2608.
    • (2011) Blood , vol.118 , pp. 2602-2608
    • Hirsch, B.1    Oseth, L.2    Cain, M.3    Trader, E.4    Pulkrabek, S.5    Lindgren, B.6
  • 28
    • 77949331310 scopus 로고    scopus 로고
    • G-CSF-induced aneuploidy does not affect CD34+ cells and does not require cell division
    • Marmier-Savet C, Larosa F, Legrand F, Witz B, Michallet M, Ranta D et al. G-CSF-induced aneuploidy does not affect CD34+ cells and does not require cell division. Blood 2010; 115: 910-911.
    • (2010) Blood , vol.115 , pp. 910-911
    • Marmier-Savet, C.1    Larosa, F.2    Legrand, F.3    Witz, B.4    Michallet, M.5    Ranta, D.6
  • 29
    • 84856287199 scopus 로고    scopus 로고
    • Effects of granulocyte-colony-stimulating factor on Monosomy 7 aneuploidy in healthy hematopoietic stem cell and granulocyte donors
    • Olnes MJ, Poon A, Miranda SJ, Pfannes L, Tucker Z, Loeliger K et al. Effects of granulocyte-colony-stimulating factor on Monosomy 7 aneuploidy in healthy hematopoietic stem cell and granulocyte donors. Transfusion 2012; 52: 537-541.
    • (2012) Transfusion , vol.52 , pp. 537-541
    • Olnes, M.J.1    Poon, A.2    Miranda, S.J.3    Pfannes, L.4    Tucker, Z.5    Loeliger, K.6
  • 30
    • 0034769641 scopus 로고    scopus 로고
    • Comparison of gene expression in CD34+ cells from bone marrow and G-CSF-mobilized peripheral blood by high-density oligonucleotide array analysis
    • Graf L, Heimfeld S, Torok-Storb B. Comparison of gene expression in CD34+ cells from bone marrow and G-CSF-mobilized peripheral blood by high-density oligonucleotide array analysis. Biol Blood Marrow Transplant 2001; 7: 486-494.
    • (2001) Biol Blood Marrow Transplant , vol.7 , pp. 486-494
    • Graf, L.1    Heimfeld, S.2    Torok-Storb, B.3
  • 31
    • 84896704960 scopus 로고    scopus 로고
    • Granulocyte colony-stimulating factor produces long-term changes in gene and microRNA expression profiles in CD34+ cells from healthy donors
    • Baez A, Martin-Antonio B, Piruat JI, Prats C, Alvarez-Laderas I, Barbado MV et al. Granulocyte colony-stimulating factor produces long-term changes in gene and microRNA expression profiles in CD34+ cells from healthy donors. Haematologica 2014; 99: 243-251.
    • (2014) Haematologica , vol.99 , pp. 243-251
    • Baez, A.1    Martin-Antonio, B.2    Piruat, J.I.3    Prats, C.4    Alvarez-Laderas, I.5    Barbado, M.V.6
  • 32
    • 33847047101 scopus 로고    scopus 로고
    • Changes in gene expression pattern following granulocyte colony-stimulating factor administration to normal stem cell sibling donors
    • Amariglio N, Jacob-Hirsch J, Shimoni A, Leiba M, Rechavi G, Nagler A. Changes in gene expression pattern following granulocyte colony-stimulating factor administration to normal stem cell sibling donors. Acta Haematol 2007; 117: 68-73.
    • (2007) Acta Haematol , vol.117 , pp. 68-73
    • Amariglio, N.1    Jacob-Hirsch, J.2    Shimoni, A.3    Leiba, M.4    Rechavi, G.5    Nagler, A.6
  • 34
    • 0029865189 scopus 로고    scopus 로고
    • Safety of AlloPBPCT donors: Biometrical considerations on monitoring long term risks
    • Hasenclever D, Sextro M. Safety of AlloPBPCT donors: biometrical considerations on monitoring long term risks. Bone Marrow Transplant 1996; 17: S28-S30.
    • (1996) Bone Marrow Transplant , vol.17 , pp. S28-S30
    • Hasenclever, D.1    Sextro, M.2
  • 35
    • 84902150458 scopus 로고    scopus 로고
    • Lower risk of serious adverse events and no increased risk of cancer after PBSC versus bone marrow donation
    • Pulsipher MA, Chitphakdithai P, Logan BR, Navarro WH, Levine JE, Miller JP et al. Lower risk of serious adverse events and no increased risk of cancer after PBSC versus bone marrow donation. Blood 2014; 123: 3655-3663.
    • (2014) Blood , vol.123 , pp. 3655-3663
    • Pulsipher, M.A.1    Chitphakdithai, P.2    Logan, B.R.3    Navarro, W.H.4    Levine, J.E.5    Miller, J.P.6
  • 36
    • 84883467932 scopus 로고    scopus 로고
    • G-CSF in Healthy Allogeneic Stem Cell Donors
    • Holig K. G-CSF in Healthy Allogeneic Stem Cell Donors. Transfus Med Hemother 2013; 40: 225-235.
    • (2013) Transfus Med Hemother , vol.40 , pp. 225-235
    • Holig, K.1
  • 40
    • 84871314905 scopus 로고    scopus 로고
    • Safety and efficacy of healthy volunteer stem cell mobilization with filgrastim G-CSF and mobilized stem cell apheresis: Results of a prospective longitudinal 5-year follow-up study
    • Mueller MM, Bialleck H, Bomke B, Brauninger S, Varga C, Seidl C et al. Safety and efficacy of healthy volunteer stem cell mobilization with filgrastim G-CSF and mobilized stem cell apheresis: results of a prospective longitudinal 5-year follow-up study. Vox Sang 2013; 104: 46-54.
    • (2013) Vox Sang , vol.104 , pp. 46-54
    • Mueller, M.M.1    Bialleck, H.2    Bomke, B.3    Brauninger, S.4    Varga, C.5    Seidl, C.6


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.