The impact of HIV on presentation and outcome of bacterial sepsis and other causes of acute febrile illness in Gabon

Infection

Volumn 43, Issue 4, 2015, Pages 443-451

  Huson, Michaëla A M ^a,b   Kalkman, Rachel ^a,b   Stolp, Sebastiaan M ^a,b   Janssen, Saskia ^a,b   Alabi, Abraham S ^a   Beyeme, Justin O ^a   van der Poll, Tom ^a   Grobusch, Martin P ^a,b  

^a UNIVERSITY OF AMSTERDAM   (Netherlands)

^b ALBERT SCHWEITZER HOSPITAL   (Gabon)

Author keywords

Bacteremia; Fever; HIV; Malaria; Sepsis; Tuberculosis

Indexed keywords

ANTI HUMAN IMMUNODEFICIENCY VIRUS AGENT; ANTIINFECTIVE AGENT; ANTIMALARIAL AGENT;

ABDOMINAL INFECTION; ADULT; ANTIBIOTIC THERAPY; ARTICLE; BACTEREMIA; BACTERIAL BLOODSTREAM INFECTION; BACTERIAL SEPSIS; BLOOD CULTURE; BLOODSTREAM INFECTION; CD4 LYMPHOCYTE COUNT; DIAGNOSTIC TEST; DISEASE SEVERITY; FEMALE; FEVER; GABON; HELP SEEKING BEHAVIOR; HIGHLY ACTIVE ANTIRETROVIRAL THERAPY; HOSPITAL ADMISSION; HUMAN; HUMAN IMMUNODEFICIENCY VIRUS INFECTION; HYPOTHERMIA; LENGTH OF STAY; LUNG TUBERCULOSIS; MAJOR CLINICAL STUDY; MALARIA; MALARIA TESTING; MALE; MIXED INFECTION; MORTALITY; PARASITEMIA; PATIENT COUNSELING; PNEUMONIA; SEPSIS; SOFT TISSUE INFECTION; STREPTOCOCCUS PNEUMONIAE; URINARY TRACT INFECTION; AIDS-RELATED OPPORTUNISTIC INFECTIONS; COINFECTION; COMPLICATION; MIDDLE AGED; PROSPECTIVE STUDY; RISK FACTOR;

ADULT; AIDS-RELATED OPPORTUNISTIC INFECTIONS; COINFECTION; FEMALE; FEVER; GABON; HIV INFECTIONS; HUMANS; MALARIA; MALE; MIDDLE AGED; PROSPECTIVE STUDIES; RISK FACTORS; SEPSIS;

EID: 84938417015     PISSN: 03008126     EISSN: 14390973     Source Type: Journal    
DOI: 10.1007/s15010-015-0753-2     Document Type: Article

References (30)

1. Flateau C, Le Loup G, Pialoux G. Consequences of HIV infection on malaria and therapeutic implications: a systematic review. Lancet Infect Dis. 2011;11:541–56. doi:10.1016/S1473-3099(11)70031-7.
2. Huson MA, Stolp SM, van der Poll T, Grobusch MP. Community-acquired bacterial bloodstream infections in HIV-infected patients: a systematic review. Clin Infect Dis. 2014;58:79–92. doi:10.1093/cid/cit596.
3. Wenzel RP. Treating sepsis. N Engl J Med. 2002;347:966–7. doi:10.1056/NEJMp020096.
4. Reddy EA, Shaw AV, Crump JA. Community-acquired bloodstream infections in Africa: a systematic review and meta-analysis. Lancet Infect Dis. 2010;10:417–32. doi:10.1016/S1473-3099(10)70072-4.
5. HIV/AIDS JUNPo. Global report: UNAIDS report on the global AIDS epidemic. 2013.
6. Organization WH. World malaria report 2013.
7. Holmes CB, Losina E, Walensky RP, Yazdanpanah Y, Freedberg KA. Review of human immunodeficiency virus type 1-related opportunistic infections in sub-Saharan Africa. Clin Infect Dis. 2003;36:652–62. doi:10.1086/367655.
8. Janssen S, Huson MA, Belard S, Stolp S, Kapata N, Bates M, et al. TB and HIV in the Central African region: current knowledge and knowledge gaps. Infection. 2014;42:281–94. doi:10.1007/s15010-013-0568-y.
9. Stolp SM, Huson MA, Janssen S, Beyeme JO, Grobusch MP. Tuberculosis patients hospitalized in the Albert Schweitzer Hospital, Lambarene, Gabon—a retrospective observational study. Clin Microbiol Infect. 2013;19:E499–501. doi:10.1111/1469-0691.12278.
10. Bone RC, Sibbald WJ, Sprung CL. The ACCP-SCCM consensus conference on sepsis and organ failure. Chest. 1992;101:1481–3.
11. Planche T, Krishna S, Kombila M, Engel K, Faucher JF, Ngou-Milama E, et al. Comparison of methods for the rapid laboratory assessment of children with malaria. Am J Trop Med Hyg. 2001;65:599–602.
12. Garner JS, Jarvis WR, Emori TG, Horan TC, Hughes JM. CDC definitions for nosocomial infections, 1988. Am J Infect Control. 1988;16:128–40.
13. Calandra T, Cohen J, International Sepsis Forum Definition of Infection in the ICUCC. The international sepsis forum consensus conference on definitions of infection in the intensive care unit. Crit Care Med. 2005;33:1538–48.
14. Horan TC, Andrus M, Dudeck MA. CDC/NHSN surveillance definition of health care-associated infection and criteria for specific types of infections in the acute care setting. Am J Infect Control. 2008;36:309–32. doi:10.1016/j.ajic.2008.03.002.
15. Finney CA, Ayi K, Wasmuth JD, Sheth PM, Kaul R, Loutfy MR, et al. HIV infection deregulates innate immunity to malaria despite combination antiretroviral therapy. AIDS. 2013;27:325–35. doi:10.1097/QAD.0b013e32835b3dfa.
16. Murray CJ, Rosenfeld LC, Lim SS, Andrews KG, Foreman KJ, Haring D, et al. Global malaria mortality between 1980 and 2010: a systematic analysis. Lancet. 2012;379:413–31. doi:10.1016/S0140-6736(12)60034-8.
17. Bouyou-Akotet MK, Offouga CL, Mawili-Mboumba DP, Essola L, Madoungou B, Kombila M. Falciparum malaria as an emerging cause of fever in adults living in Gabon, Central Africa. BioMed Res Int. 2014;2014:351281. doi:10.1155/2014/351281.
18. Mharakurwa S, Mutambu SL, Mberikunashe J, Thuma PE, Moss WJ, Mason PR, et al. Changes in the burden of malaria following scale up of malaria control interventions in Mutasa District, Zimbabwe. Malar J. 2013;12:223. doi:10.1186/1475-2875-12-223.
19. Gilks CF, Ojoo SA, Ojoo JC, Brindle RJ, Paul J, Batchelor BI, et al. Invasive pneumococcal disease in a cohort of predominantly HIV-1 infected female sex-workers in Nairobi, Kenya. Lancet. 1996;347:718–23.
20. Tabu C, Breiman RF, Ochieng B, Aura B, Cosmas L, Audi A, et al. Differing burden and epidemiology of non-Typhi Salmonella bacteremia in rural and urban Kenya, 2006-2009. PLoS One. 2012;7:e31237. doi:10.1371/journal.pone.0031237.
21. Huson MA, Grobusch MP, van der Poll T. The effect of HIV infection on the host response to bacterial sepsis. Lancet Infect Dis. 2015;15:95–108.
22. Zumla A, Raviglione M, Hafner R, von Reyn CF. Tuberculosis. N Engl J Med. 2013;368:745–55. doi:10.1056/NEJMra1200894.
23. Morgan DJ, Okeke IN, Laxminarayan R, Perencevich EN, Weisenberg S. Non-prescription antimicrobial use worldwide: a systematic review. Lancet Infect Dis. 2011;11:692–701. doi:10.1016/S1473-3099(11)70054-8.
24. Cremers AL, Janssen S, Huson MA, Bikene G, Bélard S, Gerrets RPM, et al. Perceptions, health care seeking behaviour and implementation of a tuberculosis control programme in Lambaréné, Gabon. Public Health Action. 2013;3:328–32.
25. Lubinga SJ, Kintu A, Atuhaire J, Asiimwe S. Concomitant herbal medicine and Antiretroviral Therapy (ART) use among HIV patients in Western Uganda: a cross-sectional analysis of magnitude and patterns of use, associated factors and impact on ART adherence. AIDS Care. 2012;24:1375–83. doi:10.1080/09540121.2011.648600.
26. Peltzer K, Preez NF, Ramlagan S, Fomundam H, Anderson J, Chanetsa L. Antiretrovirals and the use of traditional, complementary and alternative medicine by HIV patients in Kwazulu-Natal, South Africa: a longitudinal study. Afr J Tradit Complement Altern Med. 2011;8:337–45.
27. Organization WH. Consolidated guidelines on the use of antiretroviral drugs for treating and preventing HIV infection. 2013.
28. Roura M, Watson-Jones D, Kahawita TM, Ferguson L, Ross DA. Provider-initiated testing and counselling programmes in sub-Saharan Africa: a systematic review of their operational implementation. AIDS. 2013;27:617–26. doi:10.1097/QAD.0b013e32835b7048.
29. Obermeyer CM, Bott S, Bayer R, Desclaux A, Baggaley R, Group MS. HIV testing and care in Burkina Faso, Kenya, Malawi and Uganda: ethics on the ground. BMC Int Health Hum Rights. 2013;13:6. doi:10.1186/1472-698X-13-6.
30. Leroy EM, Nkoghe D, Ollomo B, Nze-Nkogue C, Becquart P, Grard G, et al. Concurrent chikungunya and dengue virus infections during simultaneous outbreaks, Gabon, 2007. Emerg Infect Dis. 2009;15:591–3. doi:10.3201/eid1504.080664.