Molecular spectrum of BRAF, NRAS and KRAS gene mutations in plasma cell dyscrasias: Implication for MEK-ERK pathway activation

Oncotarget

Volumn 6, Issue 27, 2015, Pages 24205-24217

  Lionetti, Marta ^a   Barbieri, Marzia ^b   Todoerti, Katia ^c   Agnelli, Luca ^a   Marzorati, Simona ^a   Fabris, Sonia ^b   Ciceri, Gabriella ^a   Galletti, Serena ^a   Milesi, Giulia ^b   Manzoni, Martina ^a   Mazzoni, Mara ^d   Greco, Angela ^d   Tonon, Giovanni ^e   Musto, Pellegrino ^c   Baldini, Luca ^a,b   Neri, Antonino ^a,b  

^a UNIVERSITY OF MILAN   (Italy)

^b FONDAZIONE IRCCS CA GRANDA OSPEDALE MAGGIORE POLICLINICO   (Italy)

^c REFERRAL CANCER CENTER OF BASILICATA   (Italy)

^d NATIONAL CANCER INSTITUTE   (Italy)

^e SAN RAFFAELE HOSPITAL   (Italy)

Author keywords

BRAF; Multiple myeloma; Next generation sequencing; Plasma cell leukemia; RAS

Indexed keywords

B RAF KINASE; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE KINASE; VEMURAFENIB; BRAF PROTEIN, HUMAN; GUANOSINE TRIPHOSPHATASE; INDOLE DERIVATIVE; KRAS PROTEIN, HUMAN; MAP2K1 PROTEIN, HUMAN; MEMBRANE PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE KINASE 1; NRAS PROTEIN, HUMAN; PROTEIN P21; SULFONAMIDE;

ADULT; AGED; ARTICLE; BRAF GENE; CANCER RECURRENCE; CONTROLLED STUDY; FEMALE; GENE; GENE EXPRESSION; GENE EXPRESSION PROFILING; GENE MUTATION; GENETIC TRANSCRIPTION; GENETIC VARIABILITY; HUMAN; HUMAN CELL; MAJOR CLINICAL STUDY; MALE; MULTIPLE MYELOMA; MUTATIONAL ANALYSIS; ONCOGENE K RAS; ONCOGENE N RAS; PLASMA CELL DYSCRASIA; PLASMA CELL LEUKEMIA; SIGNAL TRANSDUCTION; APOPTOSIS; EXOME; GENE EXPRESSION REGULATION; GENETICS; LEUKEMIA; METABOLISM; MIDDLE AGED; MUTATION; PARAPROTEINEMIA; PRINCIPAL COMPONENT ANALYSIS; TUMOR CELL LINE; VERY ELDERLY;

ADULT; AGED; AGED, 80 AND OVER; APOPTOSIS; CELL LINE, TUMOR; EXOME; EXTRACELLULAR SIGNAL-REGULATED MAP KINASES; FEMALE; GENE EXPRESSION PROFILING; GENE EXPRESSION REGULATION, LEUKEMIC; GENE EXPRESSION REGULATION, NEOPLASTIC; GTP PHOSPHOHYDROLASES; HUMANS; INDOLES; LEUKEMIA; MALE; MAP KINASE KINASE 1; MAP KINASE SIGNALING SYSTEM; MEMBRANE PROTEINS; MIDDLE AGED; MULTIPLE MYELOMA; MUTATION; PARAPROTEINEMIAS; PRINCIPAL COMPONENT ANALYSIS; PROTO-ONCOGENE PROTEINS B-RAF; PROTO-ONCOGENE PROTEINS P21(RAS); SULFONAMIDES;

EID: 84938360089     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.4434     Document Type: Article

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