Highly effective non-viral antitumor gene therapy system comprised of biocompatible small plasmid complex particles consisting of pDNA, anionic polysaccharide, and fully deprotected linear polyethylenimine

Pharmaceutics

Volumn 7, Issue 3, 2015, Pages 152-164

  Koyama, Yoshiyuki ^a,b   Sugiura, Kikuya ^b   Yoshihara, Chieko ^c   Inaba, Toshio ^b   Ito, Tomoko ^a,b  

^a FUKUJUJI HOSPITAL   (Japan)

^b Osaka Prefecture University   (Japan)

^c OTSUMA WOMEN'S UNIVERSITY   (Japan)

Author keywords

Antitumor; Chondroitin sulfate; Cytokine; Freeze drying; Hyaluronic acid; Nanoparticle; Non viral; Plasmid; Polyethylenimine Max ; Transfection

Indexed keywords

CHONDROITIN SULFATE; CYTOKINE; HYALURONIC ACID; PLASMID DNA; POLYETHYLENEIMINE; POLYSACCHARIDE;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ANTINEOPLASTIC ACTIVITY; ARTICLE; BIOCOMPATIBILITY; CANCER GENE THERAPY; COMPLEX FORMATION; CONTROLLED STUDY; CYTOKINE PRODUCTION; DRUG EFFICACY; DRUG STABILITY; FREEZE DRYING; GENE EXPRESSION; GENETIC TRANSFECTION; IN VITRO GENE TRANSFER; IN VIVO STUDY; MALE; MOUSE; NONHUMAN; NONVIRAL GENE DELIVERY SYSTEM; OUTCOME ASSESSMENT; PH; TUMOR VOLUME;

EID: 84938354997     PISSN: None     EISSN: 19994923     Source Type: Journal    
DOI: 10.3390/pharmaceutics7030152     Document Type: Article

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