Plasma TNF-α is associated with inflammation and nutrition status in community-dwelling Japanese elderly

Journal of Nutritional Science and Vitaminology

Volumn 61, Issue 3, 2015, Pages 263-269

  Oe, Yukiko ^a   Mochizuki, Kazuki ^a,b   Miyauchi, Rie ^a   Misaki, Yasumi ^a   Kasezawa, Nobuhiko ^c   Tohyama, Kazushige ^c   Goda, Toshinao ^a  

^a UNIVERSITY OF SHIZUOKA   (Japan)

^b UNIVERSITY OF YAMANASHI   (Japan)

^c SBS Shizuoka Health Promotion Center   (Japan)

Author keywords

Elderly; Inflammation; Malnutrition; TNF

Indexed keywords

C REACTIVE PROTEIN; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; SERUM ALBUMIN; TUMOR NECROSIS FACTOR ALPHA; BIOLOGICAL MARKER; CREATININE; EGFR PROTEIN, HUMAN; EPIDERMAL GROWTH FACTOR RECEPTOR; IL6 PROTEIN, HUMAN; INTERLEUKIN 6; SERUM GLOBULIN; TRIACYLGLYCEROL;

ADULT; AGED; ALBUMIN BLOOD LEVEL; ALCOHOL CONSUMPTION; ARTICLE; CALORIC INTAKE; CREATININE BLOOD LEVEL; FEMALE; GERIATRICS; GLOBULIN BLOOD LEVEL; GLOMERULUS FILTRATION; HUMAN; INFLAMMATION; INSULIN RESISTANCE; LEUKOCYTE COUNT; MALE; MALNUTRITION; MONOCYTE; NORMAL HUMAN; NUTRITIONAL STATUS; PHYSICAL ACTIVITY; QUESTIONNAIRE; SMOKING; TRIACYLGLYCEROL LIPASE BLOOD LEVEL; URIC ACID BLOOD LEVEL; AGE; AGING; ASIAN CONTINENTAL ANCESTRY GROUP; BLOOD; BODY MASS; CROSS-SECTIONAL STUDY; INDEPENDENT LIVING; JAPAN; NONPARAMETRIC TEST; RISK FACTOR; STATISTICAL MODEL; STATISTICS AND NUMERICAL DATA; VERY ELDERLY;

AGE FACTORS; AGED; AGED, 80 AND OVER; AGING; ASIAN CONTINENTAL ANCESTRY GROUP; BIOMARKERS; BODY MASS INDEX; C-REACTIVE PROTEIN; CHOLESTEROL, HDL; CREATININE; CROSS-SECTIONAL STUDIES; FEMALE; HUMANS; INDEPENDENT LIVING; INFLAMMATION; INSULIN RESISTANCE; INTERLEUKIN-6; JAPAN; LEUKOCYTE COUNT; LINEAR MODELS; MALE; MALNUTRITION; MONOCYTES; NUTRITIONAL STATUS; RECEPTOR, EPIDERMAL GROWTH FACTOR; RISK FACTORS; SERUM ALBUMIN; SERUM GLOBULINS; STATISTICS, NONPARAMETRIC; TRIGLYCERIDES; TUMOR NECROSIS FACTOR-ALPHA;

EID: 84938336933     PISSN: 03014800     EISSN: 18817742     Source Type: Journal    
DOI: 10.3177/jnsv.61.263     Document Type: Article

References (30)

1. Shingh T, Newman AB. 2011. Inflammatory markers in population studies of aging. Aging Res Rev 10: 319-329.
2. Cesari M, Penninx BW, Newman AB, Kritchevsky SB, Nicklas BJ, Sutton-Tyrrell K, Rubin SM, Ding J, Simonssick EM, Harris TB, Pahor M. 2003. Inflammatory markers and onset of cardiovascular events: results from the Health ABC study. Circulation 108: 2317-2322.
3. Cesari M, Penninx BW, Newman AB, Kritchevsky SB, Nicklas BJ, Sutton-Tyrrell K, Tracy RP, Rubin SM, Harris TB, Pahor M. 2003. Inflammatory markers and cardiovascular disease (The Health Aging and Body Composition [Health ABC] Study). Am J Cardiol 92: 522-528.
4. Penninx BW, Kritchevsky SB, Newman AB, Nicklas BJ, Simonsick EM, Rubin S, Nevitt M, Visser M, Harris T, Pahor M. 2004. Inflammatory markers and incident mobility limitation in the elderly. J Am Geriatr Soc 52: 1105-1113.
5. Hubbard RE, O'Mahony MS, Savva GM, Calver BL, Woodhouse KW. 2009. Inflammation and frailty measures in older people. J Cell Mol Med 13: 3103-3109.
6. Weisberg SP, McCann D, Desai M, Rosenbaum M, Leibel RL, Ferrante AW Jr. 2003. Obesity is associated with macrophage accumulation in adipose tissue. J Clin Invest 112: 1796-1808.
7. Maggio M, Guralnik JM, Longo DL, Ferrucci L. 2006. Interleukin-6 in aging and chronic disease: a magnificent pathway. J Gerontol A Biol Sci Med Sci 61: 575-584.
8. Williams LM, Lali F, Willetts K, Balague C, Godessart N, Brennan F, Feldmann M, Foxwell BM. 2008. Rac mediates TNF-induced cytokine production via modulation of NF-kappaB. Mol Immunol 45: 2446-2454.
9. Trayhurn P, Wood IS. 2005. Signalling role of adipose tissue: adipokines and inflammation in obesity. Biochem Soc Trans 33: 1078-1081.
10. Reuben DB, Cheh AI, Harris TB, Ferrucci L, Rowe JW, Tracy RP, Seeman TE. 2002. Peripheral blood markers of inflammation predict mortality and functional decline in high-functioning community-dwelling older persons. J Am Geriatr Soc 50: 638-644.
11. Reuben DB, Judd-Hamilton L, Harris TB, Seeman TE. 2003. The associations between physical activity and inflammatory markers in high-functioning older persons: MacArthur Studies of Successful Aging. J Am Geriatr Soc 51: 1125-1130.
12. Hsu FC, Kritchevsky SB, Liu Y, Kanaya A, Newman AB, Perry SE, Visser M, Pahor M, Harris TB, Nicklas BJ. 2009. Association between inflammatory components and physical function in the health, aging, and body composition study: a principal component analysis approach. J Gerontol A Biol Sci Med Sci 64: 581-589.
13. Visser M, Pahor M, Taaffe DR, Goodpaster BH, Simonsick EM, Newman AB, Nevitt M, Harris TB. 2002. Relationship of interleukin-6 and tumor necrosis factor-alpha with muscle mass and muscle strength in elderly men and women: the Health ABC Study. J Gerontol A Biol Sci Med Sci 57: M326-M332.
14. Schaap LA, Pluijm SM, Deeg DJ, Harris TB, Kritchevsky SB, Newman AB, Colbert LH, Pahor M, Rubin SM, Tylavsky FA, Visser M. 2009. Higher inflammatory marker levels in older persons: associations with 5-year change in muscle mass and muscle strength. J Gerontol A Biol Sci Med Sci 64: 1183-1189.
15. Schaap LA, Pluijm SM, Deeg DJ, Visser M. 2006. Inflammatory markers and loss of muscle mass (sarcopenia) and strength. Am J Med 119: 526. e9-e17.
16. Kobayashi S, Murakami K, Sasaki S, Okubo H, Hirota N, Notsu A, Fukui M, Date C. 2011. Comparison of relative validity of food group intakes estimated by comprehensive and brief-type self-administered diet history questionnaires against 16 d dietary records in Japanese adults. Public Health Nutr 14: 1200-1211.
17. Seino Y, Nanjo K, Tajima N, Kadowaki T, Kashiwagi A, Araki E, Ito C, Inagaki N, Iwamoto Y, Kasuga M, Hanafusa T, Haneda M, Ueki K. 2010. Report of the committee on the classification and diagnostic criteria of diabetes mellitus. J Diabetes Investig 1: 212-228.
18. de Gonzalo-Calvo D, Neizert K, Fernandez M, Vega-Naredo I, Caballero B, Garcia-Macia M, Suarez FM, Rodriguez-Colunga MJ, Solano JJ, Coto-Montes A. 2010. Differential inflammatory responses in aging and disease: TNF-a and IL-6 as possible biomarkers. Free Radic Biol Med 49: 733-737.
19. Bruunsgaard H, Skinhoj P, Pedersen AN, Schroll M, Pedersen BK. 2000. Ageing, tumour necrosis factor-alpha (TNF-a) and atherosclerosis. Clin Exp Immunol 121: 255-260.
20. Vettor R, Milan G, Rossato M, Federspil G. 2005. Review article: adipocytokines and insulin resistance. Aliment Pharmacol Ther 22 (Suppl 2): 3-10.
21. Cesari M, Onder G, Zamboni V, Capoluongo E, Russo A, Bernabei R, Pahor M, Landi F. 2009. C-reactive protein and lipid parameters in older persons aged 80 years and older. J Nutr Health Aging 13: 587-593.
22. Lyngdoh T, Marques-Vidal P, Paccaud F, Preisig M, Waeber G, Bochud M, Vollenweider P. 2011. Elevated serum uric acid is associated with high circulating inflammatory cytokines in the population-based Colaus study. PLoS One 6 (5): e19901.
23. Yeo ES, Hwang JY, Park JE, Choi YJ, Huh KB, Kim WY. 2010. Tumor necrosis factor (TNF-a) and C-reactive protein (CRP) are positively associated with the risk of chronic kidney disease in patients with type 2 diabetes. Yonsei Med J 51: 519-525.
24. Leng SX, Xue QL, Huang Y, Ferrucci L, Fried LP, Walston JD. 2005. Baseline total and specific differential white blood cell counts and 5-year all-cause mortality in community-dwelling older women. Exp Gerontol 40: 982-987.
25. Ruggiero C, Metter EJ, Cherubini A, Maggio M, Sen R, Najjar SS, Windham GB, Ble A, Senin U, Ferrucci L. 2007. White blood cell count and mortality in the Baltimore Longitudinal Study of Aging. J Am Coll Cardiol 49: 1841-1850.
26. Leng SX, Xue QL, Tian J, Walston DJ, Fried LP. 2007. Inflammation and frailty in older woman. J Am Geriatr Soc 55: 864-871.
27. Walston J, McBurnie MA, Newman A, Tracy RP, Kop WJ, Hirsch CH, Gottdiener J, Fried LP. 2002. Frailty and activation of the inflammation and coagulation systems with and without clinical comorbidities: results from the Cardiovascular Health Study. Arch Intern Med 162: 2333-2341.
28. Leng SX, Xue QL, Tian J, Huang Y, Yeh SH, Fried LP. 2009. Associations of neutrophil and monocyte counts with frailty in community-dwelling disabled older women: results from the Women's Health and Aging Studies l. Exp Gerontol 44: 511-516.
29. Fulop T, Larbi A, Witkowski JM, McElhaney J, Loeb M, Mitnitski A, Pawelec G. 2010. Aging, frailty and agerelated diseases. Biogerontology 11: 547-563.
30. Don BR, Kaysen G. 2004. Serum albumin: relationship to inflammation and nutrition. Semin Dial 17: 432-437.