Towards Optimal Design of Cancer Nanomedicines: Multi-stage Nanoparticles for the Treatment of Solid Tumors

Annals of Biomedical Engineering

Volumn 43, Issue 9, 2015, Pages 2291-2300

  Stylianopoulos, Triantafyllos ^a   Economides, Eva Athena ^a   Baish, James W ^b   Fukumura, Dai ^c   Jain, Rakesh K ^c  

^a UNIVERSITY OF CYPRUS   (Cyprus)

^b BUCKNELL UNIVERSITY   (United States)

^c MASSACHUSETTS GENERAL HOSPITAL   (United States)

Author keywords

Drug delivery; Mathematical modeling; Nano carriers; Tumor microenvironment

Indexed keywords

BINDING ENERGY; DISEASES; DRUG DELIVERY; DRUG PRODUCTS; MATHEMATICAL MODELS; OPTIMAL SYSTEMS; PARTICLE SIZE; TUMORS;

CHEMOTHERAPEUTIC DRUGS; DRUG RELEASE KINETICS; ENHANCED PERMEABILITY AND RETENTION EFFECTS; NANO-CARRIERS; PRIMARY NANOPARTICLES; SECONDARY PARTICLES; TUMOR MICROENVIRONMENT; UNIFORM DISTRIBUTION;

NANOPARTICLES;

ANTINEOPLASTIC AGENT; NANOCARRIER; NANOPARTICLE; PACLITAXEL; DRUG CARRIER;

ARTICLE; BINDING AFFINITY; CANCER CHEMOTHERAPY; DRUG DELIVERY SYSTEM; DRUG DESIGN; DRUG RELEASE; MATHEMATICAL MODEL; PARTICLE SIZE; PRIORITY JOURNAL; PROCESS OPTIMIZATION; SOLID TUMOR; BIOLOGICAL MODEL; CHEMISTRY; HUMAN; NEOPLASMS;

ANTINEOPLASTIC AGENTS; DRUG CARRIERS; DRUG DESIGN; HUMANS; MODELS, BIOLOGICAL; NANOPARTICLES; NEOPLASMS;

EID: 84938286510     PISSN: 00906964     EISSN: 15739686     Source Type: Journal    
DOI: 10.1007/s10439-015-1276-9     Document Type: Article

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