GC-MS, LC-MSn, LC-high resolution-MSn, and NMR studies on the metabolism and toxicological detection of mesembrine and mesembrenone, the main alkaloids of the legal high "Kanna" isolated from Sceletium tortuosum

Analytical and Bioanalytical Chemistry

Volumn 407, Issue 3, 2015, Pages 761-778

  Meyer, Golo M J ^a   Wink, Carina S D ^a   Zapp, Josef ^b   Maurer, Hans H ^a  

^a SAARLAND UNIVERSITY   (Germany)

^b SAARLAND UNIVERSITY   (Germany)

Author keywords

GC MS; Kanna; LC (HR) MSn; Mesembrenone; Mesembrine; Metabolism

Indexed keywords

ALKALOIDS; BIOMOLECULES; BODY FLUIDS; GAS CHROMATOGRAPHY; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; METABOLISM; PHYSIOLOGY; RATS; SULFUR COMPOUNDS;

GAS CHROMATOGRAPHY-MASS SPECTROMETRIES (GC-MS); GC-MS; HIGH RESOLUTION MASS SPECTROMETRY; KANNA; MESEMBRENONE; MESEMBRINE; PHENOLIC METABOLITES; SCREENING APPROACHES;

METABOLITES;

RATTUS; SCELETIUM TORTUOSUM;

INDOLE ALKALOID; MESEMBRENONE; MESEMBRINE;

AFRICAN MEDICINE; AIZOACEAE; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; DRUG EFFECTS; HUMAN; LIQUID CHROMATOGRAPHY; LIVER; MALE; MASS FRAGMENTOGRAPHY; MASS SPECTROMETRY; METABOLISM; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PROCEDURES; STANDARD; STANDARDS; URINE; WISTAR RAT;

AIZOACEAE; ANIMALS; CHROMATOGRAPHY, LIQUID; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; HUMANS; INDOLE ALKALOIDS; LIVER; MAGNETIC RESONANCE SPECTROSCOPY; MALE; MASS SPECTROMETRY; MEDICINE, AFRICAN TRADITIONAL; MOLECULAR STRUCTURE; RATS, WISTAR; REFERENCE STANDARDS;

EID: 84938267816     PISSN: 16182642     EISSN: 16182650     Source Type: Journal    
DOI: 10.1007/s00216-014-8109-9     Document Type: Article

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