The enigmatic linguistic cerebellum: Clinical relevance and unanswered questions on nonmotor speech and language deficits in cerebellar disorders

Cerebellum and Ataxias

Volumn 1, Issue 1, 2014, Pages

  Mariën, Peter ^a,b   Beaton, Alan ^c,d  

^a VRIJE UNIVERSITEIT BRUSSEL   (Belgium)

^b MIDDELHEIM HOSPITAL   (Belgium)

^c SWANSEA UNIVERSITY   (United Kingdom)

^d ABERYSTWYTH UNIVERSITY   (United Kingdom)

Author keywords

Agraphia; Aphasia; Apraxia of speech; Cerebellum; Dyslexia; FMRI; Functional topography; Imaging; Language; Phonology; Semantics; SPECT; Speech; Syntax; Verbal fluency

Indexed keywords

AGRAPHIA; APHASIA; APRAXIA; APRAXIC AGRAPHIA; ATAXIC APHASIA; AUTONOMIC NERVOUS SYSTEM FUNCTION; CENTRAL AGRAPHIA; CEREBELLAR INDUCED APHASIA; CEREBELLUM DISEASE; COGNITION; CONNECTOME; DYSARTHRIA; DYSGRAPHIA; DYSLEXIA; FUNCTIONAL NEUROIMAGING; HUMAN; LANGUAGE DISABILITY; LINGUISTICS; NEUROMODULATION; PATHOGENESIS; PRIORITY JOURNAL; REVIEW; SEMANTICS; SENSORIMOTOR FUNCTION; SPEECH DISORDER; SURFACE DYSGRAPHIA; VISUAL DYSLEXIA;

EID: 84938242671     PISSN: None     EISSN: 20538871     Source Type: Journal    
DOI: 10.1186/2053-8871-1-12     Document Type: Review

References (26)

1. Manto M, Bower JM, Conforto AB, Delgado-García JM, da Guarda SN, Gerwig M, Habas C, Hagura N, Ivry RB, Mariën P, Molinari M, Naito E, Nowak DA, Oulad Ben Taib N, Pelisson D, Tesche CD, Tilikete C, Timmann D: Consensus paper: roles of the cerebellum in motor control - the diversity of ideas on cerebellar involvement in movement. Cerebellum 2012, 11: 457-487. 10.1007/s12311-011-0331-9
2. Mariën P, Ackermann H, Adamaszek M, Barwood CHS, Beaton A, Desmond J, De Witte E, Fawcett AJ, Hertrich I, Küper M, Leggio M, Marvel C, Molinari M, Murdoch BE, Nicolson RI, Schmahmann JD, Stoodley CJ, Thürling M, Timmann D, Wouters E, Ziegler W: Consensus Paper: Language and the cerebellum: an ongoing enigma. Cerebellum 2014, 13: 386-410.
3. Holmes G: The symptoms of acute cerebellar injuries due to gunshot injuries. Brain 1917, 40: 401-534.
4. Lechtenberg R, Gilman S: Speech disorders in cerebellar disease. Ann Neurol 1978, 3: 285-290. 10.1002/ana.410030402
5. Ackermann H, Vogel M, Petersen D, Poremba M: Speech deficits in ischaemic cerebellar lesions. J Neurol 1992, 239: 223-227. 10.1007/BF00839144
6. Urban PP, Marx J, Hunsche S, Gawehn J, Vucurevic G, Wicht S, Massinger C, Stoeter P, Hopf HC: Cerebellar speech representation: lesion topography in dysarthria as derived from cerebellar ischemia and functional magnetic resonance imaging. Arch Neurol 2003, 60: 965-972. 10.1001/archneur.60.7.965
7. Urban PP: Speech motor deficits in cerebellar infarctions. Brain Lang 2013, 127: 323-326. 10.1016/j.bandl.2013.10.001
8. De Smet HJ, Baillieux H, Catsman-Berrevoets C, De Deyn PP, Mariën P, Paquier PF: Postoperative motor speech production in children with the syndrome of 'cerebellar' mutism and subsequent dysarthria: a critical review of the literature. Eur J Paed Neurol 2007, 11: 193-207. 10.1016/j.ejpn.2007.01.007
9. Mariën P, Verhoeven J, Engelborghs S, Rooker S, Pickut BA, De Deun PP: A role for the cerebellum in motor speech planning: evidence from foreign accent syndrome. Clin Neurol Neurosurg 2006, 108: 518-522. 10.1016/j.clineuro.2005.06.006
10. Pitsaka M, Tsitouras V: Cerebellar mutism: a review. J Neurosurg Pediatr 2013, 12: 604-614. 10.3171/2013.8.PEDS13168
11. Leggio M, Silveri M, Petrosini L, Molinari M: Phonological grouping is specifically affected in cerebellar patients: a verbal fluency study. J Neurol Neurosur Ps 2000, 69: 102-106. 10.1136/jnnp.69.1.102
12. Stuss DT, Alexander MP: Is there a dysexecutive syndrome? Philos T Roy Soc B 2007, 362: 901-915. 10.1098/rstb.2007.2096
13. Mariën P, Saerens J, Nanhoe R, Moens E, Nagels G, Pickut B, Dierckx RA, De Deyn PP: Cerebellar induced aphasia: case report of cerebellar induced prefrontal aphasic language phenomena supported by SPECT findings. J Neurol Sci 1996, 144: 34-43. 10.1016/S0022-510X(96)00059-7
14. Adamaszek M, Strecker K, Kessler C: Impact of cerebellar lesion on syntactic processing evidenced by event-related potentials. Neurosci Lett 2012,12(2):78-82.
15. Schmahmann JD, Sherman JC: The cerebellar cognitive affective syndrome. Brain 1998, 121: 561-579. 10.1093/brain/121.4.561
16. Justus T: The cerebellum and English grammatical morphology: evidence from production, comprehension, and grammaticality judgements. J Cogn Neurosci 2004,16(4):1115-1130.
17. Mariën P, Engelborghs S, Fabbro F, De Deyn PP: The lateralized linguistic cerebellum: a review and a new hypothesis. Brain Lang 2001, 79: 580-600. 10.1006/brln.2001.2569
18. Moretti R, Bava A, Torre P, Antonello RM, Cazzato G: Reading errors in patients with cerebellar vermis lesions. J Neurol 2002, 249: 461-468. 10.1007/s004150200040
19. Moretti R, Torre P, Antonello RM, Carraro N, Zambito-Marsala S, Ukmar MJ, Capus L, Gioulis M, Cazzato G, Bava A: Peculiar aspects of reading and writing performances in patients with olivopontocerebellar atrophy. Percept Mot Skills 2002, 94: 677-694. 10.2466/pms.2002.94.2.677
20. Fabbro F, Tavano A, Corti S, Bresolin N, De Fabritiis P, Borgatti R: Long-term neuropsychological deficits after cerebellar infarctions in two young adult twins. Neuropsychologia 2004,42(4):536-545. 10.1016/j.neuropsychologia.2003.09.006
21. Mariën P, Baillieux H, De Smet HJ, Engelborghs S, Wilssens I, Paquier P, De Deyn PP: Cognitive, linguistic and affective disturbances following a right superior cerebellar artery infarction: a case study. Cortex 2009, 45: 527-536. 10.1016/j.cortex.2007.12.010
22. De Smet HJ, Engelborghs S, Paquier PF, De Deyn PP, Mariën P: Cerebellar-induced apraxic agraphia: a review and three new cases. Brain Cognition 2011,76(3):424-434. 10.1016/j.bandc.2010.12.006
23. Frank B, Schoch B, Hein-Kropp C, Dimitrova A, Hövel M, Ziegler W, Gizewski ER, Timmann D: Verb generation in children and adolescents with acute cerebellar lesions. Neuropsychologia 2007, 45: 977-988. 10.1016/j.neuropsychologia.2006.09.002
24. Stoodley CJ, Schmahmann JD: Functional topography in the human cerebellum: a meta-analysis of neuroimaging studies. Neuroimage 2009, 44: 489-501. 10.1016/j.neuroimage.2008.08.039
25. Schmahmann JD, Doyon J, Toga A, Petrides M, Evans A: MRI Atlas of the Human Cerebellum. San Diego: Academic Press; 2000.
26. Schmahmann JD, Macmore J, Vangel M: Cerebellar stroke without motor deficit: clinical evidence for motor and non-motor domains within the human cerebellum. Neuroscience 2009, 162: 852-861. 10.1016/j.neuroscience.2009.06.023