-
1
-
-
2942529235
-
Subtractive proteomic mapping of the endothelial surface in lung and solid tumours for tissue-specific therapy
-
Oh P, Li Y, Yu J, Durr E, Krasinska KM, Carver LA, Testa JE, Schnitzer JE (2004) Subtractive proteomic mapping of the endothelial surface in lung and solid tumours for tissue-specific therapy. Nature 429:629-635
-
(2004)
Nature
, vol.429
, pp. 629-635
-
-
Oh, P.1
Li, Y.2
Yu, J.3
Durr, E.4
Krasinska, K.M.5
Carver, L.A.6
Testa, J.E.7
Schnitzer, J.E.8
-
2
-
-
0036488496
-
Specialization of tumour vasculature
-
Ruoslahti E (2002) Specialization of tumour vasculature. Nat Rev Cancer 2:83-90
-
(2002)
Nat Rev Cancer
, vol.2
, pp. 83-90
-
-
Ruoslahti, E.1
-
3
-
-
0034682892
-
Genes expressed in human tumor endothelium
-
St Croix B, Rago C, Velculescu V, Traverso G, Romans KE, Montgomery E, Lal A, Riggins GJ, Lengauer C, Vogelstein B, Kinzler KW (2000) Genes expressed in human tumor endothelium. Science 289:1197-1202
-
(2000)
Science
, vol.289
, pp. 1197-1202
-
-
St Croix, B.1
Rago, C.2
Velculescu, V.3
Traverso, G.4
Romans, K.E.5
Montgomery, E.6
Lal, A.7
Riggins, G.J.8
Lengauer, C.9
Vogelstein, B.10
Kinzler, K.W.11
-
4
-
-
0029932458
-
Organ targeting in vivo using phage display peptide libraries
-
Pasqualini R, Ruoslahti E (1996) Organ targeting in vivo using phage display peptide libraries. Nature 380:364-366
-
(1996)
Nature
, vol.380
, pp. 364-366
-
-
Pasqualini, R.1
Ruoslahti, E.2
-
5
-
-
0037022366
-
Targeting the prostate for destruction through a vascular address
-
Arap W, Haedicke W, Bernasconi M, Kain R, Rajotte D, Krajewski S, Ellerby HM, Bredesen DE, Pasqualini R, Ruoslahti E (2002) Targeting the prostate for destruction through a vascular address. Proc Natl Acad Sci U S A 99:1527-1531
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 1527-1531
-
-
Arap, W.1
Haedicke, W.2
Bernasconi, M.3
Kain, R.4
Rajotte, D.5
Krajewski, S.6
Ellerby, H.M.7
Bredesen, D.E.8
Pasqualini, R.9
Ruoslahti, E.10
-
6
-
-
0032528192
-
Molecular heterogeneity of the vascular endothelium revealed by in vivo phage display
-
Rajotte D, Arap W, Hagedorn M, Koivunen E, Pasqualini R, Ruoslahti E (1998) Molecular heterogeneity of the vascular endothelium revealed by in vivo phage display. J Clin Invest 102:430-437
-
(1998)
J Clin Invest
, vol.102
, pp. 430-437
-
-
Rajotte, D.1
Arap, W.2
Hagedorn, M.3
Koivunen, E.4
Pasqualini, R.5
Ruoslahti, E.6
-
7
-
-
24944535233
-
Molecular profiling of heart endothelial cells
-
Zhang L, Hoffman JA, Ruoslahti E (2005) Molecular profiling of heart endothelial cells. Circulation 112:1601-1611
-
(2005)
Circulation
, vol.112
, pp. 1601-1611
-
-
Zhang, L.1
Hoffman, J.A.2
Ruoslahti, E.3
-
8
-
-
0033564799
-
NG2 proteoglycanbinding peptides target tumor neovasculature
-
Burg MA, Pasqualini R, Arap W, Ruoslahti E, Stallcup WB (1999) NG2 proteoglycanbinding peptides target tumor neovasculature. Cancer Res 59:2869-2874
-
(1999)
Cancer Res
, vol.59
, pp. 2869-2874
-
-
Burg, M.A.1
Pasqualini, R.2
Arap, W.3
Ruoslahti, E.4
Stallcup, W.B.5
-
9
-
-
0036063778
-
A tumor-homing peptide with a targeting specificity related to lymphatic vessels
-
Laakkonen P, Porkka K, Hoffman JA, Ruoslahti E (2002) A tumor-homing peptide with a targeting specificity related to lymphatic vessels. Nat Med 8:751-755
-
(2002)
Nat Med
, vol.8
, pp. 751-755
-
-
Laakkonen, P.1
Porkka, K.2
Hoffman, J.A.3
Ruoslahti, E.4
-
10
-
-
0030940283
-
Alpha v integrins as receptors for tumor targeting by circulating ligands
-
Pasqualini R, Koivunen E, Ruoslahti E (1997) Alpha v integrins as receptors for tumor targeting by circulating ligands. Nat Biotechnol 15: 542-546
-
(1997)
Nat Biotechnol
, vol.15
, pp. 542-546
-
-
Pasqualini, R.1
Koivunen, E.2
Ruoslahti, E.3
-
11
-
-
0037188542
-
A fragment of the HMGN2 protein homes to the nuclei of tumor cells and tumor endothelial cells in vivo
-
Porkka K, Laakkonen P, Hoffman JA, Bernasconi M, Ruoslahti E (2002) A fragment of the HMGN2 protein homes to the nuclei of tumor cells and tumor endothelial cells in vivo. Proc Natl Acad Sci U S A 99:7444-7449
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 7444-7449
-
-
Porkka, K.1
Laakkonen, P.2
Hoffman, J.A.3
Bernasconi, M.4
Ruoslahti, E.5
-
12
-
-
0344309914
-
Progressive vascular changes in a transgenic mouse model of squamous cell carcinoma
-
Hoffman JA, Giraudo E, Singh M, Zhang L, Inoue M, Porkka K, Hanahan D, Ruoslahti E (2003) Progressive vascular changes in a transgenic mouse model of squamous cell carcinoma. Cancer Cell 4:383-391
-
(2003)
Cancer Cell
, vol.4
, pp. 383-391
-
-
Hoffman, J.A.1
Giraudo, E.2
Singh, M.3
Zhang, L.4
Inoue, M.5
Porkka, K.6
Hanahan, D.7
Ruoslahti, E.8
-
13
-
-
0344185348
-
Stagespecific vascular markers revealed by phage display in a mouse model of pancreatic islet tumorigenesis
-
Joyce JA, Laakkonen P, Bernasconi M, Bergers G, Ruoslahti E, Hanahan D (2003) Stagespecific vascular markers revealed by phage display in a mouse model of pancreatic islet tumorigenesis. Cancer Cell 4:393-403
-
(2003)
Cancer Cell
, vol.4
, pp. 393-403
-
-
Joyce, J.A.1
Laakkonen, P.2
Bernasconi, M.3
Bergers, G.4
Ruoslahti, E.5
Hanahan, D.6
-
15
-
-
84875451385
-
Peptide-based glioma-targeted drug delivery vector gHoPe2
-
Eriste E, Kurrikoff K, Suhorutsenko J, Oskolkov N, Copolovici DM, Jones S, Laakkonen P, Howl J, Langel U (2013) Peptide-based glioma-targeted drug delivery vector gHoPe2. Bioconjug Chem 24:305-313
-
(2013)
Bioconjug Chem
, vol.24
, pp. 305-313
-
-
Eriste, E.1
Kurrikoff, K.2
Suhorutsenko, J.3
Oskolkov, N.4
Copolovici, D.M.5
Jones, S.6
Laakkonen, P.7
Howl, J.8
Langel, U.9
-
16
-
-
80054795004
-
Targeted nanoparticle enhanced proapoptotic peptide as potential therapy for glioblastoma
-
Agemy L, Friedmann-Morvinski D, Kotamraju VR, Roth L, Sugahara KN, Girard OM, Mattrey RF, Verma IM, Ruoslahti E (2011) Targeted nanoparticle enhanced proapoptotic peptide as potential therapy for glioblastoma. Proc Natl Acad Sci U S A 108:17450-17455
-
(2011)
Proc Natl Acad Sci U S A
, vol.108
, pp. 17450-17455
-
-
Agemy, L.1
Friedmann-Morvinski, D.2
Kotamraju, V.R.3
Roth, L.4
Sugahara, K.N.5
Girard, O.M.6
Mattrey, R.F.7
Verma, I.M.8
Ruoslahti, E.9
-
17
-
-
84914159376
-
Novel target for peptide-based imaging and treatment of brain tumors
-
Hyvonen M, Enback J, Huhtala T, Lammi J, Sihto H, Weisell J, Joensuu H, Rosenthal-Aizman K, El-Andaloussi S, Langel U, Narvanen A, Bergers G, Laakkonen P (2014) Novel target for peptide-based imaging and treatment of brain tumors. Mol Cancer Ther 13:996-1007
-
(2014)
Mol Cancer Ther
, vol.13
, pp. 996-1007
-
-
Hyvonen, M.1
Enback, J.2
Huhtala, T.3
Lammi, J.4
Sihto, H.5
Weisell, J.6
Joensuu, H.7
Rosenthal-Aizman, K.8
El-Andaloussi, S.9
Langel, U.10
Narvanen, A.11
Bergers, G.12
Laakkonen, P.13
-
18
-
-
84883806964
-
Tumour homing peptide- functionalized porous silicon nanovectors for cancer therapy
-
Kinnari PJ, Hyvonen ML, Makila EM, Kaasalainen MH, Rivinoja A, Salonen JJ, Hirvonen JT, Laakkonen PM, Santos HA (2013) Tumour homing peptide- functionalized porous silicon nanovectors for cancer therapy. Biomaterials 34:9134-9141
-
(2013)
Biomaterials
, vol.34
, pp. 9134-9141
-
-
Kinnari, P.J.1
Hyvonen, M.L.2
Makila, E.M.3
Kaasalainen, M.H.4
Rivinoja, A.5
Salonen, J.J.6
Hirvonen, J.T.7
Laakkonen, P.M.8
Santos, H.A.9
-
19
-
-
77957859054
-
Identification of a cardiac specific protein transduction domain by in vivo biopanning using a M13 phage peptide display library in mice
-
Zahid M, Phillips BE, Albers SM, Giannoukakis N, Watkins SC, Robbins PD (2010) Identification of a cardiac specific protein transduction domain by in vivo biopanning using a M13 phage peptide display library in mice. PLoS One 5, e12252
-
(2010)
Plos One
, vol.5
-
-
Zahid, M.1
Phillips, B.E.2
Albers, S.M.3
Giannoukakis, N.4
Watkins, S.C.5
Robbins, P.D.6
-
20
-
-
58149091387
-
Distinct uptake routes of cell-penetrating peptide conjugates
-
Lundin P, Johansson H, Guterstam P, Holm T, Hansen M, Langel U, EL Andaloussi S (2008) Distinct uptake routes of cell-penetrating peptide conjugates. Bioconjug Chem 19: 2535-2542
-
(2008)
Bioconjug Chem
, vol.19
, pp. 2535-2542
-
-
Lundin, P.1
Johansson, H.2
Guterstam, P.3
Holm, T.4
Hansen, M.5
Langel, U.6
El Andaloussi, S.7
-
21
-
-
34548183128
-
Assessing the delivery efficacy and internalization route of cell-penetrating peptides
-
El Andaloussi S, Guterstam P, Langel U (2007) Assessing the delivery efficacy and internalization route of cell-penetrating peptides. Nat Protoc 2:2043-2047
-
(2007)
Nat Protoc
, vol.2
, pp. 2043-2047
-
-
El Andaloussi, S.1
Guterstam, P.2
Langel, U.3
-
22
-
-
35248880092
-
TAT transduction: The molecular mechanism and therapeutic prospects
-
Gump JM, Dowdy SF (2007) TAT transduction: the molecular mechanism and therapeutic prospects. Trends Mol Med 13:443-448
-
(2007)
Trends Mol Med
, vol.13
, pp. 443-448
-
-
Gump, J.M.1
Dowdy, S.F.2
-
23
-
-
70749103751
-
Tissue-penetrating delivery of compounds and nanoparticles into tumors
-
Sugahara KN, Teesalu T, Karmali PP, Kotamraju VR, Agemy L, Girard OM, Hanahan D, Mattrey RF, Ruoslahti E (2009) Tissue-penetrating delivery of compounds and nanoparticles into tumors. Cancer Cell 16:510-520
-
(2009)
Cancer Cell
, vol.16
, pp. 510-520
-
-
Sugahara, K.N.1
Teesalu, T.2
Karmali, P.P.3
Kotamraju, V.R.4
Agemy, L.5
Girard, O.M.6
Hanahan, D.7
Mattrey, R.F.8
Ruoslahti, E.9
-
24
-
-
70349482671
-
C-end rule peptides mediate neuropilin-1-dependent cell, vascular, and tissue penetration
-
Teesalu T, Sugahara KN, Kotamraju VR, Ruoslahti E (2009) C-end rule peptides mediate neuropilin-1-dependent cell, vascular, and tissue penetration. Proc Natl Acad Sci U S A 106:16157-16162
-
(2009)
Proc Natl Acad Sci U S A
, vol.106
, pp. 16157-16162
-
-
Teesalu, T.1
Sugahara, K.N.2
Kotamraju, V.R.3
Ruoslahti, E.4
-
25
-
-
77952901022
-
Coadministration of a tumor-penetrating peptide enhances the efficacy of cancer drugs
-
Sugahara KN, Teesalu T, Karmali PP, Kotamraju VR, Agemy L, Greenwald DR, Ruoslahti E (2010) Coadministration of a tumor-penetrating peptide enhances the efficacy of cancer drugs. Science 328:1031-1035
-
(2010)
Science
, vol.328
, pp. 1031-1035
-
-
Sugahara, K.N.1
Teesalu, T.2
Karmali, P.P.3
Kotamraju, V.R.4
Agemy, L.5
Greenwald, D.R.6
Ruoslahti, E.7
-
26
-
-
84891868266
-
A free cysteine prolongs the half-life of a homing peptide and improves its tumor-penetrating activity
-
Pang HB, Braun GB, She ZG, Kotamraju VR, Sugahara KN, Teesalu T, Ruoslahti E (2014) A free cysteine prolongs the half-life of a homing peptide and improves its tumor-penetrating activity. J Control Release 175:48-53
-
(2014)
J Control Release
, vol.175
, pp. 48-53
-
-
Pang, H.B.1
Braun, G.B.2
She, Z.G.3
Kotamraju, V.R.4
Sugahara, K.N.5
Teesalu, T.6
Ruoslahti, E.7
-
27
-
-
0021818675
-
Filamentous fusion phage: Novel expression vectors that display cloned antigens on the virion surface
-
Smith GP (1985) Filamentous fusion phage: novel expression vectors that display cloned antigens on the virion surface. Science 228: 1315-1317
-
(1985)
Science
, vol.228
, pp. 1315-1317
-
-
Smith, G.P.1
-
28
-
-
0036366705
-
Overview of antibody phage-display technology and its applications
-
Hoogenboom HR (2002) Overview of antibody phage-display technology and its applications. Methods Mol Biol 178:1-37
-
(2002)
Methods Mol Biol
, vol.178
, pp. 1-37
-
-
Hoogenboom, H.R.1
-
29
-
-
34548771163
-
A novel cell-penetrating peptide, M918, for efficient delivery of proteins and peptide nucleic acids
-
El-Andaloussi S, Johansson HJ, Holm T, Langel U (2007) A novel cell-penetrating peptide, M918, for efficient delivery of proteins and peptide nucleic acids. Mol Ther 15:1820-1826
-
(2007)
Mol Ther
, vol.15
, pp. 1820-1826
-
-
El-Andaloussi, S.1
Johansson, H.J.2
Holm, T.3
Langel, U.4
-
30
-
-
79952201944
-
Identification and characterization of tissue-specific protein transduction domains using peptide phage display
-
Zahid M, Robbins PD (2011) Identification and characterization of tissue-specific protein transduction domains using peptide phage display. Methods Mol Biol 683:277-289
-
(2011)
Methods Mol Biol
, vol.683
, pp. 277-289
-
-
Zahid, M.1
Robbins, P.D.2
|