Interplay between ultrastructural findings and atherothrombotic complications in type 2 diabetes mellitus

Cardiovascular Diabetology

Volumn 14, Issue 1, 2015, Pages

  Soma, Prashilla ^a   Pretorius, Etheresia ^a  

^a UNIVERSITY OF PRETORIA   (South Africa)

Author keywords

Atherosclerosis; Diabetes; Erythrocytes; Fibrin; Morphology; Platelets

Indexed keywords

FIBRIN;

ATHEROSCLEROSIS; ATHEROSCLEROTIC PLAQUE; BLOOD CLOTTING; CELL FUNCTION; ERYTHROCYTE AGGREGATION; ERYTHROCYTE DEFORMABILITY; ERYTHROCYTE STRUCTURE; FIBRIN NETWORK; HUMAN; NON INSULIN DEPENDENT DIABETES MELLITUS; PATHOGENESIS; REVIEW; THROMBOCYTE FUNCTION; THROMBOCYTE STRUCTURE; THROMBOSIS; ANIMAL; BLOOD; COMPLICATION; DIABETES MELLITUS, TYPE 2; DIABETIC ANGIOPATHIES; ERYTHROCYTE; FIBRINOLYSIS; METABOLISM; MORTALITY; RISK ASSESSMENT; RISK FACTOR; THROMBOCYTE; ULTRASTRUCTURE;

ANIMALS; ATHEROSCLEROSIS; BLOOD COAGULATION; BLOOD PLATELETS; DIABETES MELLITUS, TYPE 2; DIABETIC ANGIOPATHIES; ERYTHROCYTES; FIBRIN; FIBRINOLYSIS; HUMANS; PLAQUE, ATHEROSCLEROTIC; RISK ASSESSMENT; RISK FACTORS; THROMBOSIS;

EID: 84938082979     PISSN: None     EISSN: 14752840     Source Type: Journal    
DOI: 10.1186/s12933-015-0261-9     Document Type: Review

References (59)

1. van Rooy MJ, Pretorius E (2014) Obesity, hypertension and hypercholesterolemia as risk factors for atherosclerosis leading to ischemic events. Curr Med Chem 21(19):2121-2129
2. Colwell JA, Nesto RW (2003) The platelet in diabetes: focus on prevention of ischemic events. Diabetes Care 26(7):2181-2188
3. Creager MA, Luscher TF, Cosentino F, Beckman JA (2003) Diabetes and vascular disease: pathophysiology, clinical consequences, and medical therapy: part I. Circulation 108(12):1527-1532
4. Kluft C, Jespersen J (2002) Review: diabetes as a procoagulant condition. Br J Diabetes Vasc Dis 2(5):358-362
5. van Rooy MJ, Pretorius E (2015) Metabolic syndrome, platelet activation and the development of transient ischemic attack or thromboembolic stroke. Thromb Res 135(3):434-442
6. Ferreiro JL, Gomez-Hospital JA, Angiolillo DJ (2010) Platelet abnormalities in diabetes mellitus. Diabetes Vasc Dis Res 7(4):251-259
7. Blair P, Flaumenhaft R (2009) Platelet alpha-granules: basic biology and clinical correlates. Blood Rev 23(4):177-189
8. Lesurtel M, Graf R, Aleil B, Walther DJ, Tian Y, Jochum W et al (2006) Platelet-derived serotonin mediates liver regeneration. Science (New York, NY) 312(5770):104-107
9. Heemskerk JW, Bevers EM, Lindhout T (2002) Platelet activation and blood coagulation. Thromb Haemost 88(2):186-193
10. Rosing J, van Rijn JL, Bevers EM, van Dieijen G, Comfurius P, Zwaal RF (1985) The role of activated human platelets in prothrombin and factor X activation. Blood 65(2):319-332
11. Eibl N, Krugluger W, Streit G, Schrattbauer K, Hopmeier P, Schernthaner G (2004) Improved metabolic control decreases platelet activation markers in patients with type-2 diabetes. Eur J Clin Invest 34(3):205-209
12. Tschoepe D, Schultheiss HP, Kolarov P, Schwippert B, Dannehl K, Nieuwenhuis HK et al (1993) Platelet membrane activation markers are predictive for increased risk of acute ischemic events after PTCA. Circulation 88(1):37-42
13. Vinik AI, Erbas T, Park TS, Nolan R, Pittenger GL (2001) Platelet dysfunction in type 2 diabetes. Diabetes Care 24(8):1476-1485
14. Sobol AB, Watala C (2000) The role of platelets in diabetes-related vascular complications. Diabetes Res Clin Pract 50(1):1-16
15. Pretorius E, Oberholzer HM, van der Spuy WJ, Swanepoel AC, Soma P (2011) Qualitative scanning electron microscopy analysis of fibrin networks and platelet abnormalities in diabetes. Blood Coagul Fibrinolysis Int J Haemost Thromb 22(6):463-467
16. Burnier L, Fontana P, Kwak BR, Angelillo-Scherrer A (2009) Cell-derived microparticles in haemostasis and vascular medicine. Thromb Haemost 101(3):439-451
17. Morel O, Toti F, Hugel B, Bakouboula B, Camoin-Jau L, Dignat-George F et al (2006) Procoagulant microparticles: disrupting the vascular homeostasis equation? Arterioscler Thromb Vasc Biol 26(12):2594-2604
18. Alzahrani SH, Ajjan RA (2010) Coagulation and fibrinolysis in diabetes. Diabetes Vasc Dis Res 7(4):260-273
19. Fatah K, Silveira A, Tornvall P, Karpe F, Blomback M, Hamsten A (1996) Proneness to formation of tight and rigid fibrin gel structures in men with myocardial infarction at a young age. Thromb Haemost 76(4):535-540
20. Swanepoel AC, Nielsen VG, Pretorius E (2015) Viscoelasticity and ultrastructure in coagulation and inflammation: two diverse techniques, one conclusion. Inflammation 38(4):1707-1726
21. Kell DB, Pretorius E (2015) The simultaneous occurrence of both hypercoagulability and hypofibrinolysis in blood and serum during systemic inflammation, and the roles of iron and fibrin(ogen). Integr Biol Quant Biosci Nano Macro 7(1):24-52
22. Boden G, Vaidyula VR, Homko C, Cheung P, Rao AK (2007) Circulating tissue factor procoagulant activity and thrombin generation in patients with type 2 diabetes: effects of insulin and glucose. J Clin Endocrinol Metab 92(11):4352-4358
23. Breitenstein A, Tanner FC, Luscher TF (2010) Tissue factor and cardiovascular disease: quo vadis? Circ J 74(1):3-12
24. Undas A, Wiek I, Stepien E, Zmudka K, Tracz W (2008) Hyperglycemia is associated with enhanced thrombin formation, platelet activation, and fibrin clot resistance to lysis in patients with acute coronary syndrome. Diabetes Care 31(8):1590-1595
25. Corrado E, Rizzo M, Coppola G, Fattouch K, Novo G, Marturana I et al (2010) An update on the role of markers of inflammation in atherosclerosis. J Atheroscler Thromb 17(1):1-11
26. Jorneskog G, Egberg N, Fagrell B, Fatah K, Hessel B, Johnsson H et al (1996) Altered properties of the fibrin gel structure in patients with IDDM. Diabetologia 39(12):1519-1523
27. Marchi-Cappelletti R, Suarez-Nieto N (2010) Preliminary study of the fibrin structure in hypertensive, dyslipidemic and type 2 diabetic patients. Invest Clin 51(3):315-324
28. Pieters M, Covic N, van der Westhuizen FH, Nagaswami C, Baras Y, Toit Loots D (2008) Glycaemic control improves fibrin network characteristics in type 2 diabetes-a purified fibrinogen model. Thromb Haemost 99(4):691-700
29. Balasubramaniam K, Viswanathan GN, Marshall SM, Zaman AG (2012) Increased atherothrombotic burden in patients with diabetes mellitus and acute coronary syndrome: a review of antiplatelet therapy. Cardiol Res Pract 2012:909154
30. Brown GE, Ritter LS, McDonagh PF, Cohen Z (2014) Functional enhancement of platelet activation and aggregation by erythrocytes: role of red cells in thrombosis. Peer J PrePrints 2:e351v351
31. Virmani R, Roberts WC (1983) Extravasated erythrocytes, iron, and fibrin in atherosclerotic plaques of coronary arteries in fatal coronary heart disease and their relation to luminal thrombus: frequency and significance in 57 necropsy patients and in 2958 five mm segments of 224 major epicardial coronary arteries. Am Heart J 105(5):788-797
32. Mahindrakar YS, Suryakar AN, Ankush RD, Katkam RV, Kumbhar KM (2007) Comparison between erythrocyte hemoglobin and spectrin glycosylation and role of oxidative stress in type-2 diabetes mellitus. Indian J Clin Biochem 22(1):91-94
33. Os D (2009) Rheological and electrical behaviour of erythrocytes in patients with diabetes mellitus. Rom J Biophys 19(14):239-250
34. Gersh KC, Nagaswami C, Weisel JW (2009) Fibrin network structure and clot mechanical properties are altered by incorporation of erythrocytes. Thromb Haemost 102(6):1169-1175
35. Wohner N (2008) Role of cellular elements in thrombus formation and dissolution. Cardiovasc Hematol Agents Med Chem 6(3):224-228
36. Schmid-Schonbein H, Wells R, Goldstone J (1969) Influence of deformability of human red cells upon blood viscosity. Circ Res 25(2):131-143
37. Baynes JW (1991) Role of oxidative stress in development of complications in diabetes. Diabetes 40(4):405-412
38. Arbustini E (2007) Total erythrocyte membrane cholesterol: an innocent new marker or an active player in acute coronary syndromes? J Am Coll Cardiol 49(21):2090-2092
39. Davies MJ (1996) Stability and instability: two faces of coronary atherosclerosis. the Paul Dudley White Lecture 1995. Circulation 94(8):2013-2020
40. Schwartz RS, Madsen JW, Rybicki AC, Nagel RL (1991) Oxidation of spectrin and deformability defects in diabetic erythrocytes. Diabetes 40(6):701-708
41. Kowluru R, Bitensky MW, Kowluru A, Dembo M, Keaton PA, Buican T (1989) Reversible sodium pump defect and swelling in the diabetic rat erythrocyte: effects on filterability and implications for microangiopathy. Proc Natl Acad Sci USA 86(9):3327-3331
42. Singh M, Shin S (2009) Changes in erythrocyte aggregation and deformability in diabetes mellitus: a brief review. Indian J Exp Biol 47(1):7-15
43. Rizvi SI, Zaid MA, Anis R, Mishra N (2005) Protective role of tea catechins against oxidation-induced damage of type 2 diabetic erythrocytes. Clin Exp Pharmacol Physiol 32(1-2):70-75
44. Srour Bilto YY, Juma M, Irhimeh MR (2000) Exposure of human erythrocytes to oxygen radicals causes loss of deformability, increased osmotic fragility, lipid peroxidation and protein degradation. Clin Hemorheol Microcirc 23(1):13-21
45. Vahalkar GS, Haldankar VA (2008) RBC membrane composition in insulin dependent diabetes mellitus in context of oxidative stress. Indian J Clin Biochem 23(3):223-226
46. Buys AV, Van Rooy MJ, Soma P, Van Papendorp D, Lipinski B, Pretorius E (2013) Changes in red blood cell membrane structure in type 2 diabetes: a scanning electron and atomic force microscopy study. Cardiovasc Diabetol 12:25
47. Shin S, Ku Y, Babu N, Singh M (2007) Erythrocyte deformability and its variation in diabetes mellitus. Indian J Exp Biol 45(1):121-128
48. McMurchie EJ, Raison JK (1979) Membrane lipid fluidity and its effect on the activation energy of membrane-associated enzymes. Biochim Biophys Acta 554(2):364-374
49. Wali RK, Jaffe S, Kumar D, Kalra VK (1988) Alterations in organization of phospholipids in erythrocytes as factor in adherence to endothelial cells in diabetes mellitus. Diabetes 37(1):104-111
50. Lipinski B, Pretorius E (2012) Novel pathway of ironinduced blood coagulation: implications for diabetes mellitus and its complications. Pol Arch Med Wewn 122(3):115-122
51. Pretorius E (2013) The adaptability of red blood cells. Cardiovasc Diabetol 12:63
52. Lipinski B, Pretorius E, Oberholzer HM, Van Der Spuy WJ (2012) Iron enhances generation of fibrin fibers in human blood: implications for pathogenesis of stroke. Microsc Res Tech 75(9):1185-1190
53. Pretorius E, Kell DB (2014) Diagnostic morphology: biophysical indicators for iron-driven inflammatory diseases. Integr Biol Quant Biosci Nano Macro 6(5):486-510
54. Pretorius E, Lipinski B (2013) Iron alters red blood cell morphology. Blood 121(1):9
55. Pretorius E, Vermeulen N, Bester J (2014) Atypical erythrocytes and platelets in a patient with a pro-thrombin mutation. Platelets 25(6):461-462
56. Pretorius E, Lipinski B (2013) Thromboembolic ischemic stroke changes red blood cell morphology. Cardiovasc Pathol 22(3):241-242
57. Atici AG, Kayhan S, Aydin D, Yilmaz YA (2013) Plasma viscosity levels in pulmonary thromboembolism. Clin Hemorheol Microcirc 55(3):313-320
58. Baskurt OK, Meiselman HJ (2013) Erythrocyte aggregation: basic aspects and clinical importance. Clin Hemorheol Microcirc 53(1-2):23-37
59. Holsworth RE Jr, Cho YI, Weidman JJ, Sloop GD (2014) St Cyr JA: Cardiovascular benefits of phlebotomy: relationship to changes in hemorheological variables. Perfusion 29(2):102-116