Circulating FABP4 is a prognostic biomarker in patients with acute coronary syndrome but not in asymptomatic individuals

Arteriosclerosis, Thrombosis, and Vascular Biology

Volumn 35, Issue 8, 2015, Pages 1872-1879

  Reiser, Hans ^a,c   Klingenberg, Roland ^b   Hof, Danielle ^a   Cooksley Decasper, Seraina ^a,d   Fuchs, Nina ^b   Akhmedov, Alexander ^b   Zoller, Stefan ^e   Marques Vidal, Pedro ^f   Marti Soler, Helena ^g   Heg, Dik ^h   Landmesser, Ulf ^b,d   Rodondi, Nicolas ⁱ   MacH, Francois ^k   Windecker, Stephan ^j   Vollenweider, Peter ^f   Matter, Christian M ^b,d   Lüscher, Thomas F ^d   Von Eckardstein, Arnold ^a,c,d   Gawinecka, Joanna ^a  

^a UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^b UNIVERSITY HOSPITAL ZURICH   (Switzerland)

^c Zurich Center for Integrative Human Physiology ^*  (Switzerland)

^d UNIVERSITY OF ZURICH   (Switzerland)

^e ETH ZURICH   (Switzerland)

^f Institute of Tropical and Preventive Medicine   (Switzerland)

^g UNIVERSITY OF LAUSANNE   (Switzerland)

^h University Hospital Bern ^*  (Switzerland)

ⁱ UNIVERSITY OF BERN   (Switzerland)

^j BERN UNIVERSITY HOSPITAL   (Switzerland)

^k GENEVA UNIVERSITY HOSPITALS   (Switzerland)

more..

Author keywords

acute coronary syndrome; atherosclerosis; biological markers; FABP4 protein, human; follow up studies

Indexed keywords

AMINO TERMINAL PRO BRAIN NATRIURETIC PEPTIDE; BIOLOGICAL MARKER; C REACTIVE PROTEIN; CHOLESTEROL; CREATININE; FATTY ACID BINDING PROTEIN 4; GLUCOSE; HIGH DENSITY LIPOPROTEIN CHOLESTEROL; LOW DENSITY LIPOPROTEIN CHOLESTEROL; MESSENGER RNA; TRIACYLGLYCEROL; TROPONIN T; FABP4 PROTEIN, HUMAN; FATTY ACID BINDING PROTEIN;

ACUTE CORONARY SYNDROME; ADULT; AGE DISTRIBUTION; AREA UNDER THE CURVE; ARTICLE; ASYMPTOMATIC DISEASE; ATHEROSCLEROTIC PLAQUE; BODY MASS; CEREBROVASCULAR ACCIDENT; CHOLESTEROL BLOOD LEVEL; COHORT ANALYSIS; CONTROLLED STUDY; CORONARY ARTERY ATHEROSCLEROSIS; CORONARY ARTERY THROMBOSIS; CREATININE BLOOD LEVEL; CROSS-SECTIONAL STUDY; FEMALE; FOLLOW UP; GENE EXPRESSION PROFILING; GLUCOSE BLOOD LEVEL; HEART DEATH; HEART INFARCTION; HUMAN; MAJOR CLINICAL STUDY; MALE; MIDDLE AGED; NON ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; PERIPHERAL BLOOD MONONUCLEAR CELL; POPULATION BASED CASE CONTROL STUDY; PRIORITY JOURNAL; PROGNOSIS; PROTEOMICS; RECEIVER OPERATING CHARACTERISTIC; ST SEGMENT ELEVATION MYOCARDIAL INFARCTION; TRIACYLGLYCEROL BLOOD LEVEL; UNSTABLE ANGINA PECTORIS; AGED; BLOOD; CASE CONTROL STUDY; CORONARY ARTERY DISEASE; DISEASE COURSE; ENZYME LINKED IMMUNOSORBENT ASSAY; GENETICS; MORTALITY; MYOCARDIAL INFARCTION; PREDICTIVE VALUE; PROSPECTIVE STUDY; REPRODUCIBILITY; RISK ASSESSMENT; RISK FACTOR; TIME; UPREGULATION; VALIDATION STUDY;

ACUTE CORONARY SYNDROME; ADULT; AGED; ASYMPTOMATIC DISEASES; BIOLOGICAL MARKERS; CASE-CONTROL STUDIES; CORONARY ARTERY DISEASE; CROSS-SECTIONAL STUDIES; DISEASE PROGRESSION; ENZYME-LINKED IMMUNOSORBENT ASSAY; FATTY ACID-BINDING PROTEINS; FEMALE; GENE EXPRESSION PROFILING; HOSPITAL MORTALITY; HUMANS; MALE; MIDDLE AGED; MYOCARDIAL INFARCTION; PREDICTIVE VALUE OF TESTS; PROGNOSIS; PROSPECTIVE STUDIES; REPRODUCIBILITY OF RESULTS; RISK ASSESSMENT; RISK FACTORS; TIME FACTORS; UP-REGULATION;

EID: 84938054500     PISSN: 10795642     EISSN: 15244636     Source Type: Journal    
DOI: 10.1161/ATVBAHA.115.305365     Document Type: Article

References (28)

1. Hansson GK., Inflammation, atherosclerosis, and coronary artery disease. N Engl J Med 2005 352 1685 1695
2. Crea F, Liuzzo G., Pathogenesis of acute coronary syndromes. J Am Coll Cardiol 2013 61 1 11. doi: 10.1016/j.jacc.2012.07.064
3. GBD 2013 Mortality and Causes of Death Collaborators Global, regional, and national age-sex specific all-cause and cause-specific mortality for 240 causes of death, 1990-2013: a systematic analysis for the Global Burden of Disease Study 2013. Lancet 2015 385 117 171
4. Collinson P., The role of cardiac biomarkers in cardiovascular disease risk assessment. Curr Opin Cardiol 2014 29 366 371. doi: 10.1097/HCO.0000000000000081
5. Razzouk L, Fusaro M, Esquitin R., Novel biomarkers for risk stratification and identification of life-Threatening cardiovascular disease: troponin and beyond. Curr Cardiol Rev 2012 8 109 115
6. Schwentner C, Stenzl A, Gakis G., Monitoring high-risk bladder cancer. Curr Opin Urol 2012 22 421 426. doi: 10.1097/MOU.0b013e3283555d04
7. Peeters W, de Kleijn DP, Vink A, van de Weg S, Schoneveld AH, Sze SK, van der Spek PJ, de Vries JP, Moll FL, Pasterkamp G., Adipocyte fatty acid binding protein in atherosclerotic plaques is associated with local vulnerability and is predictive for the occurrence of adverse cardiovascular events. Eur Heart J 2011 32 1758 1768. doi: 10.1093/eurheartj/ehq387
8. Saksi J, Ijäs P, Mäyränpää MI, Low-expression variant of fatty acid-binding protein 4 favors reduced manifestations of atherosclerotic disease and increased plaque stability. Circ Cardiovasc Genet 2014 7 588 598. doi: 10.1161/CIRCGENETICS.113.000499
9. Amsterdam EA, Wenger NK, Brindis RG, ACC/AHA Task Force Members 2014 AHA/ACC guideline for the management of patients with non-ST-elevation acute coronary syndromes: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation 2014 130 2354 2394. doi: 10.1161/CIR.0000000000000133
10. Giannitsis E, Katus HA., Cardiac troponin level elevations not related to acute coronary syndromes. Nat Rev Cardiol 2013 10 623 634. doi: 10.1038/nrcardio.2013.129
11. Goff DC Jr, Lloyd-Jones DM, Bennett G, American College of Cardiology/American Heart Association Task Force on Practice Guidelines 2013 ACC/AHA guideline on the assessment of cardiovascular risk: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. Circulation 2014 129 25 suppl 2 S49 S73. doi: 10.1161/01.cir.0000437741.48606.98
12. Bawamia B, Mehran R, Qiu W, Kunadian V., Risk scores in acute coronary syndrome and percutaneous coronary intervention: a review. Am Heart J 2013 165 441 450. doi: 10.1016/j.ahj.2012.12.020
13. Cooksley-Decasper S, Reiser H, Thommen DS, Antibody phage display assisted identification of junction plakoglobin as a potential biomarker for atherosclerosis. PLoS One 2012 7 e47985. doi: 10.1371/journal.pone.0047985
14. Wyss CA, Neidhart M, Altwegg L, Spanaus KS, Yonekawa K, Wischnewsky MB, Corti R, Kucher N, Roffi M, Eberli FR, Amann-Vesti B, Gay S, von Eckardstein A, Lüscher TF, Maier W., Cellular actors, Toll-like receptors, and local cytokine profile in acute coronary syndromes. Eur Heart J 2010 31 1457 1469. doi: 10.1093/eurheartj/ehq084
15. Klingenberg R, Brokopp CE, Grivès A, Courtier A, Jaguszewski M, Pasqual N, Vlaskou Badra E, Lewandowski A, Gaemperli O, Hoerstrup SP, Maier W, Landmesser U, Lüscher TF, Matter CM., Clonal restriction and predominance of regulatory T cells in coronary thrombi of patients with acute coronary syndromes. Eur Heart J 2015 36 1041 1048. doi: 10.1093/eurheartj/eht543
16. Lee K, Santibanez-Koref M, Polvikoski T, Birchall D, Mendelow AD, Keavney B., Increased expression of fatty acid binding protein 4 and leptin in resident macrophages characterises atherosclerotic plaque rupture. Atherosclerosis 2013 226 74 81. doi: 10.1016/j.atherosclerosis.2012.09.037
17. Kralisch S, Fasshauer M., Adipocyte fatty acid binding protein: a novel adipokine involved in the pathogenesis of metabolic and vascular disease? Diabetologia 2013 56 10 21. doi: 10.1007/s00125-012-2737-4
18. Makowski L, Boord JB, Maeda K, Babaev VR, Uysal KT, Morgan MA, Parker RA, Suttles J, Fazio S, Hotamisligil GS, Linton MF., Lack of macrophage fatty-Acid-binding protein aP2 protects mice deficient in apolipoprotein E against atherosclerosis. Nat Med 2001 7 699 705. doi: 10.1038/89076
19. Cabré A, Lázaro I, Girona J, Manzanares JM, Marimón F, Plana N, Heras M, Masana L., Fatty acid binding protein 4 is increased in metabolic syndrome and with thiazolidinedione treatment in diabetic patients. Atherosclerosis 2007 195 e150 e158. doi: 10.1016/j.atherosclerosis.2007.04.045
20. Yeung DC, Xu A, Cheung CW, Wat NM, Yau MH, Fong CH, Chau MT, Lam KS., Serum adipocyte fatty acid-binding protein levels were independently associated with carotid atherosclerosis. Arterioscler Thromb Vasc Biol 2007 27 1796 1802. doi: 10.1161/ATVBAHA.107.146274
21. Miyoshi T, Onoue G, Hirohata A, Hirohata S, Usui S, Hina K, Kawamura H, Doi M, Kusano KF, Kusachi S, Ninomiya Y., Serum adipocyte fatty acid-binding protein is independently associated with coronary atherosclerotic burden measured by intravascular ultrasound. Atherosclerosis 2010 211 164 169. doi: 10.1016/j.atherosclerosis.2010.01.032
22. Doi M, Miyoshi T, Hirohata S, Nakamura K, Usui S, Takeda K, Iwamoto M, Kusachi S, Kusano K, Ito H., Association of increased plasma adipocyte fatty acid-binding protein with coronary artery disease in non-elderly men. Cardiovasc Diabetol 2011 10 44. doi: 10.1186/1475-2840-10-44
23. Liu J, Hong Y, D'Agostino RB Sr, Wu Z, Wang W, Sun J, Wilson PW, Kannel WB, Zhao D., Predictive value for the Chinese population of the Framingham CHD risk assessment tool compared with the Chinese Multi-Provincial Cohort Study. JAMA 2004 291 2591 2599. doi: 10.1001/jama.291.21.2591
24. Zheng Y, Ma W, Zeng Y, Liu J, Ye S, Chen S, Lan L, Erbel R, Liu Q., Comparative study of clinical characteristics between Chinese Han and German Caucasian patients with coronary heart disease. Clin Res Cardiol 2010 99 45 50. doi: 10.1007/s00392-009-0076-3
25. Bagheri R, Qasim AN, Mehta NN, Terembula K, Kapoor S, Braunstein S, Schutta M, Iqbal N, Lehrke M, Reilly MP., Relation of plasma fatty acid binding proteins 4 and 5 with the metabolic syndrome, inflammation and coronary calcium in patients with type-2 diabetes mellitus. Am J Cardiol 2010 106 1118 1123. doi: 10.1016/j.amjcard.2010.06.028
26. Tönjes A, Kralisch S, Lössner U, Kovacs P, Blüher M, Stumvoll M, Fasshauer M., Metabolic and genetic predictors of circulating adipocyte fatty acid-binding protein. Int J Obes (Lond) 2012 36 766 773. doi: 10.1038/ijo.2011.162
27. von Eynatten M, Breitling LP, Roos M, Baumann M, Rothenbacher D, Brenner H., Circulating adipocyte fatty acid-binding protein levels and cardiovascular morbidity and mortality in patients with coronary heart disease: a 10-year prospective study. Arterioscler Thromb Vasc Biol 2012 32 2327 2335. doi: 10.1161/ATVBAHA.112.248609
28. Chow WS, Tso AW, Xu A, Yuen MM, Fong CH, Lam TH, Lo SV, Tse HF, Woo YC, Yeung CY, Cheung BM, Lam KS., Elevated circulating adipocyte-fatty acid binding protein levels predict incident cardiovascular events in a community-based cohort: a 12-year prospective study. J Am Heart Assoc 2013 2 e004176. doi: 10.1161/JAHA.112.004176