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Volumn 64, Issue 8, 2015, Pages 1057-1066

STING activator c-di-GMP enhances the anti-tumor effects of peptide vaccines in melanoma-bearing mice

Author keywords

CD8 T cells; Immunotherapy; Peptide vaccines; STING; Type I interferon

Indexed keywords

CD40 LIGAND MONOCLONAL ANTIBODY; CD8 ANTIGEN; CYCLIC GMP; EPITOPE; INTERFERON; PEPTIDE VACCINE; POLYINOSINIC POLYCYTIDYLIC ACID; BIS(3',5')-CYCLIC DIGUANYLIC ACID; CANCER VACCINE; CD40 ANTIGEN; INTERFERON RECEPTOR; MEMBRANE PROTEIN; MONOCLONAL ANTIBODY; MPYS PROTEIN, MOUSE; SUBUNIT VACCINE;

EID: 84937978529     PISSN: 03407004     EISSN: 14320851     Source Type: Journal    
DOI: 10.1007/s00262-015-1713-5     Document Type: Article
Times cited : (86)

References (33)
  • 3
    • 0031890206 scopus 로고    scopus 로고
    • Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma
    • COI: 1:CAS:528:DyaK1cXhs1Kju7c%3D, PID: 9500606
    • Rosenberg SA, Yang JC, Schwartzentruber DJ et al (1998) Immunologic and therapeutic evaluation of a synthetic peptide vaccine for the treatment of patients with metastatic melanoma. Nat Med 4:321–327
    • (1998) Nat Med , vol.4 , pp. 321-327
    • Rosenberg, S.A.1    Yang, J.C.2    Schwartzentruber, D.J.3
  • 4
    • 79957831345 scopus 로고    scopus 로고
    • gp100 peptide vaccine and interleukin-2 in patients with advanced melanoma
    • COI: 1:CAS:528:DC%2BC3MXnt1Cmt7Y%3D, PID: 21631324
    • Schwartzentruber DJ, Lawson DH, Richards JM et al (2011) gp100 peptide vaccine and interleukin-2 in patients with advanced melanoma. N Engl J Med 364:2119–2127
    • (2011) N Engl J Med , vol.364 , pp. 2119-2127
    • Schwartzentruber, D.J.1    Lawson, D.H.2    Richards, J.M.3
  • 5
    • 0037842136 scopus 로고    scopus 로고
    • Adjuvant immunization of HLA-A2-positive melanoma patients with a modified gp100 peptide induces peptide-specific CD8+ T-cell responses
    • COI: 1:CAS:528:DC%2BD2cXptlCksLs%3D, PID: 12697882
    • Smith JW 2nd, Walker EB, Fox BA et al (2003) Adjuvant immunization of HLA-A2-positive melanoma patients with a modified gp100 peptide induces peptide-specific CD8+ T-cell responses. J Clin Oncol 21:1562–1573
    • (2003) J Clin Oncol , vol.21 , pp. 1562-1573
    • Smith, J.W.1    Walker, E.B.2    Fox, B.A.3
  • 7
    • 67149115517 scopus 로고    scopus 로고
    • Induction of type I IFN is required for overcoming tumor-specific T-cell tolerance after stem cell transplantation
    • COI: 1:CAS:528:DC%2BD1MXmslaksr0%3D, PID: 19279333
    • Horkheimer I, Quigley M, Zhu J, Huang X, Chao NJ, Yang Y (2009) Induction of type I IFN is required for overcoming tumor-specific T-cell tolerance after stem cell transplantation. Blood 113:5330–5339
    • (2009) Blood , vol.113 , pp. 5330-5339
    • Horkheimer, I.1    Quigley, M.2    Zhu, J.3    Huang, X.4    Chao, N.J.5    Yang, Y.6
  • 8
    • 84873111794 scopus 로고    scopus 로고
    • Type I interferon response and innate immune sensing of cancer
    • COI: 1:CAS:528:DC%2BC38XhsF2msrzK, PID: 23122052
    • Fuertes MB, Woo SR, Burnett B, Fu YX, Gajewski TF (2013) Type I interferon response and innate immune sensing of cancer. Trends Immunol 34:67–73
    • (2013) Trends Immunol , vol.34 , pp. 67-73
    • Fuertes, M.B.1    Woo, S.R.2    Burnett, B.3    Fu, Y.X.4    Gajewski, T.F.5
  • 10
    • 84877996512 scopus 로고    scopus 로고
    • Melanoma, version 2.2013: Featured updates to the NCCN guidelines
    • COI: 1:CAS:528:DC%2BC3sXmvVyrtLc%3D, PID: 23584343
    • Coit DG, Andtbacka R, Anker CJ et al (2013) Melanoma, version 2.2013: featured updates to the NCCN guidelines. J Natl Compr Canc Netw 11:395–407
    • (2013) J Natl Compr Canc Netw , vol.11 , pp. 395-407
    • Coit, D.G.1    Andtbacka, R.2    Anker, C.J.3
  • 12
    • 84869403247 scopus 로고    scopus 로고
    • The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response
    • COI: 1:CAS:528:DC%2BC38Xhs1CktL7E, PID: 23142775
    • Parvatiyar K, Zhang Z, Teles RM et al (2012) The helicase DDX41 recognizes the bacterial secondary messengers cyclic di-GMP and cyclic di-AMP to activate a type I interferon immune response. Nat Immunol 13:1155–1161
    • (2012) Nat Immunol , vol.13 , pp. 1155-1161
    • Parvatiyar, K.1    Zhang, Z.2    Teles, R.M.3
  • 13
    • 33846916451 scopus 로고    scopus 로고
    • Bacterial c-di-GMP is an immunostimulatory molecule
    • COI: 1:CAS:528:DC%2BD2sXht1Cgu7w%3D, PID: 17277122
    • Karaolis DK, Means TK, Yang D et al (2007) Bacterial c-di-GMP is an immunostimulatory molecule. J Immunol 178:2171–2181
    • (2007) J Immunol , vol.178 , pp. 2171-2181
    • Karaolis, D.K.1    Means, T.K.2    Yang, D.3
  • 14
    • 67651125824 scopus 로고    scopus 로고
    • A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP
    • COI: 1:CAS:528:DC%2BD1MXhtVyitLnI, PID: 19652017
    • McWhirter SM, Barbalat R, Monroe KM et al (2009) A host type I interferon response is induced by cytosolic sensing of the bacterial second messenger cyclic-di-GMP. J Exp Med 206:1899–1911
    • (2009) J Exp Med , vol.206 , pp. 1899-1911
    • McWhirter, S.M.1    Barbalat, R.2    Monroe, K.M.3
  • 15
    • 84863726252 scopus 로고    scopus 로고
    • Structure of STING bound to cyclic di-GMP reveals the mechanism of cyclic dinucleotide recognition by the immune system
    • COI: 1:CAS:528:DC%2BC38XovFyktL0%3D, PID: 22728658
    • Shu C, Yi G, Watts T, Kao CC, Li P (2012) Structure of STING bound to cyclic di-GMP reveals the mechanism of cyclic dinucleotide recognition by the immune system. Nat Struct Mol Biol 19:722–724
    • (2012) Nat Struct Mol Biol , vol.19 , pp. 722-724
    • Shu, C.1    Yi, G.2    Watts, T.3    Kao, C.C.4    Li, P.5
  • 16
    • 84899077215 scopus 로고    scopus 로고
    • Cytosolic-DNA-mediated, STING-dependent proinflammatory gene induction necessitates canonical NF-kappaB activation through TBK1
    • PID: 24600004
    • Abe T, Barber GN (2014) Cytosolic-DNA-mediated, STING-dependent proinflammatory gene induction necessitates canonical NF-kappaB activation through TBK1. J Virol 88:5328–5341
    • (2014) J Virol , vol.88 , pp. 5328-5341
    • Abe, T.1    Barber, G.N.2
  • 17
    • 0036196269 scopus 로고    scopus 로고
    • Challenges in the development of effective peptide vaccines for cancer
    • COI: 1:CAS:528:DC%2BD38XjtVCmt7s%3D, PID: 11936929
    • Buteau C, Markovic SN, Celis E (2002) Challenges in the development of effective peptide vaccines for cancer. Mayo Clin Proc 77:339–349
    • (2002) Mayo Clin Proc , vol.77 , pp. 339-349
    • Buteau, C.1    Markovic, S.N.2    Celis, E.3
  • 18
    • 71549172516 scopus 로고    scopus 로고
    • Optimized peptide vaccines eliciting extensive CD8 T-cell responses with therapeutic antitumor effects
    • COI: 1:CAS:528:DC%2BD1MXhsV2itLjK, PID: 19903852
    • Cho HI, Celis E (2009) Optimized peptide vaccines eliciting extensive CD8 T-cell responses with therapeutic antitumor effects. Cancer Res 69:9012–9019
    • (2009) Cancer Res , vol.69 , pp. 9012-9019
    • Cho, H.I.1    Celis, E.2
  • 19
    • 84865748503 scopus 로고    scopus 로고
    • TriVax-HPV: An improved peptide-based therapeutic vaccination strategy against human papillomavirus-induced cancers
    • COI: 1:CAS:528:DC%2BC38XhtVOhtL%2FO, PID: 22527249
    • Barrios K, Celis E (2012) TriVax-HPV: an improved peptide-based therapeutic vaccination strategy against human papillomavirus-induced cancers. Cancer Immunol Immunother 61:1307–1317
    • (2012) Cancer Immunol Immunother , vol.61 , pp. 1307-1317
    • Barrios, K.1    Celis, E.2
  • 20
    • 84860191757 scopus 로고    scopus 로고
    • A potent vaccination strategy that circumvents lymphodepletion for effective antitumor adoptive T-cell therapy
    • COI: 1:CAS:528:DC%2BC38Xls1Whu7c%3D, PID: 22367213
    • Cho HI, Reyes-Vargas E, Delgado JC, Celis E (2012) A potent vaccination strategy that circumvents lymphodepletion for effective antitumor adoptive T-cell therapy. Cancer Res 72:1986–1995
    • (2012) Cancer Res , vol.72 , pp. 1986-1995
    • Cho, H.I.1    Reyes-Vargas, E.2    Delgado, J.C.3    Celis, E.4
  • 21
    • 84877825063 scopus 로고    scopus 로고
    • BiVax: A peptide/poly-IC subunit vaccine that mimics an acute infection elicits vast and effective anti-tumor CD8 T-cell responses
    • COI: 1:CAS:528:DC%2BC3sXmt1eqt74%3D, PID: 23266830
    • Cho HI, Barrios K, Lee YR, Linowski AK, Celis E (2013) BiVax: a peptide/poly-IC subunit vaccine that mimics an acute infection elicits vast and effective anti-tumor CD8 T-cell responses. Cancer Immunol Immunother 62:787–799
    • (2013) Cancer Immunol Immunother , vol.62 , pp. 787-799
    • Cho, H.I.1    Barrios, K.2    Lee, Y.R.3    Linowski, A.K.4    Celis, E.5
  • 22
    • 0028070714 scopus 로고
    • Functional role of type I and type II interferons in antiviral defense
    • COI: 1:STN:280:DyaK2c3nvVCqtg%3D%3D, PID: 8009221
    • Muller U, Steinhoff U, Reis LF, Hemmi S, Pavlovic J, Zinkernagel RM, Aguet M (1994) Functional role of type I and type II interferons in antiviral defense. Science 264:1918–1921
    • (1994) Science , vol.264 , pp. 1918-1921
    • Muller, U.1    Steinhoff, U.2    Reis, L.F.3    Hemmi, S.4    Pavlovic, J.5    Zinkernagel, R.M.6    Aguet, M.7
  • 23
    • 0041419656 scopus 로고    scopus 로고
    • Tumor regression and autoimmunity after reversal of a functionally tolerant state of self-reactive CD8+ T cells
    • COI: 1:CAS:528:DC%2BD3sXms1WisL4%3D, PID: 12925674
    • Overwijk WW, Theoret MR, Finkelstein SE et al (2003) Tumor regression and autoimmunity after reversal of a functionally tolerant state of self-reactive CD8+ T cells. J Exp Med 198:569–580
    • (2003) J Exp Med , vol.198 , pp. 569-580
    • Overwijk, W.W.1    Theoret, M.R.2    Finkelstein, S.E.3
  • 24
    • 78650983452 scopus 로고    scopus 로고
    • Interferon gamma limits the effectiveness of melanoma peptide vaccines
    • COI: 1:CAS:528:DC%2BC3MXhtFGrsbo%3D, PID: 20889921
    • Cho HI, Lee YR, Celis E (2011) Interferon gamma limits the effectiveness of melanoma peptide vaccines. Blood 117:135–144
    • (2011) Blood , vol.117 , pp. 135-144
    • Cho, H.I.1    Lee, Y.R.2    Celis, E.3
  • 26
    • 1642330455 scopus 로고    scopus 로고
    • New CFSE-based assay to determine susceptibility to lysis by cytotoxic T cells of leukemic precursor cells within a heterogeneous target cell population
    • COI: 1:CAS:528:DC%2BD2cXjtVaksL8%3D, PID: 14630824
    • Jedema I, van der Werff NM, Barge RM, Willemze R, Falkenburg JH (2004) New CFSE-based assay to determine susceptibility to lysis by cytotoxic T cells of leukemic precursor cells within a heterogeneous target cell population. Blood 103:2677–2682
    • (2004) Blood , vol.103 , pp. 2677-2682
    • Jedema, I.1    van der Werff, N.M.2    Barge, R.M.3    Willemze, R.4    Falkenburg, J.H.5
  • 27
    • 0036173941 scopus 로고    scopus 로고
    • Visualization and quantification of T cell-mediated cytotoxicity using cell-permeable fluorogenic caspase substrates
    • COI: 1:CAS:528:DC%2BD38Xht1equ7g%3D, PID: 11821904
    • Liu L, Chahroudi A, Silvestri G et al (2002) Visualization and quantification of T cell-mediated cytotoxicity using cell-permeable fluorogenic caspase substrates. Nat Med 8:185–189
    • (2002) Nat Med , vol.8 , pp. 185-189
    • Liu, L.1    Chahroudi, A.2    Silvestri, G.3
  • 28
    • 80052662208 scopus 로고    scopus 로고
    • MPYS is required for IFN response factor 3 activation and type I IFN production in the response of cultured phagocytes to bacterial second messengers cyclic-di-AMP and cyclic-di-GMP
    • COI: 1:CAS:528:DC%2BC3MXhtVGmsb%2FO, PID: 21813776
    • Jin L, Hill KK, Filak H, Mogan J, Knowles H, Zhang B, Perraud AL, Cambier JC, Lenz LL (2011) MPYS is required for IFN response factor 3 activation and type I IFN production in the response of cultured phagocytes to bacterial second messengers cyclic-di-AMP and cyclic-di-GMP. J Immunol 187:2595–2601
    • (2011) J Immunol , vol.187 , pp. 2595-2601
    • Jin, L.1    Hill, K.K.2    Filak, H.3    Mogan, J.4    Knowles, H.5    Zhang, B.6    Perraud, A.L.7    Cambier, J.C.8    Lenz, L.L.9
  • 29
    • 84871005306 scopus 로고    scopus 로고
    • Survivin-specific T-cell reactivity correlates with tumor response and patient survival: A phase-II peptide vaccination trial in metastatic melanoma
    • COI: 1:CAS:528:DC%2BC38Xhs1GlsbnI, PID: 22565484
    • Becker JC, Andersen MH, Hofmeister-Muller V et al (2012) Survivin-specific T-cell reactivity correlates with tumor response and patient survival: a phase-II peptide vaccination trial in metastatic melanoma. Cancer Immunol Immunother 61:2091–2103
    • (2012) Cancer Immunol Immunother , vol.61 , pp. 2091-2103
    • Becker, J.C.1    Andersen, M.H.2    Hofmeister-Muller, V.3
  • 30
    • 77953098156 scopus 로고    scopus 로고
    • Clinical and immunological responses in metastatic melanoma patients vaccinated with a high-dose poly-epitope vaccine
    • COI: 1:CAS:528:DC%2BC3cXktFOjt7Y%3D, PID: 20043222
    • Dangoor A, Lorigan P, Keilholz U et al (2010) Clinical and immunological responses in metastatic melanoma patients vaccinated with a high-dose poly-epitope vaccine. Cancer Immunol Immunother 59:863–873
    • (2010) Cancer Immunol Immunother , vol.59 , pp. 863-873
    • Dangoor, A.1    Lorigan, P.2    Keilholz, U.3
  • 31
    • 84890147150 scopus 로고    scopus 로고
    • Exploiting the curative potential of adoptive T-cell therapy for cancer
    • COI: 1:CAS:528:DC%2BC3sXhvFequrvE
    • Hinrichs CS, Rosenberg SA (2014) Exploiting the curative potential of adoptive T-cell therapy for cancer. Immunological Rev 257:56–71
    • (2014) Immunological Rev , vol.257 , pp. 56-71
    • Hinrichs, C.S.1    Rosenberg, S.A.2
  • 32
    • 18344362061 scopus 로고    scopus 로고
    • Type I IFNs provide a third signal to CD8 T cells to stimulate clonal expansion and differentiation
    • COI: 1:CAS:528:DC%2BD2MXivFKisbg%3D, PID: 15814665
    • Curtsinger JM, Valenzuela JO, Agarwal P, Lins D, Mescher MF (2005) Type I IFNs provide a third signal to CD8 T cells to stimulate clonal expansion and differentiation. J Immunol 174:4465–4469
    • (2005) J Immunol , vol.174 , pp. 4465-4469
    • Curtsinger, J.M.1    Valenzuela, J.O.2    Agarwal, P.3    Lins, D.4    Mescher, M.F.5
  • 33
    • 0036644556 scopus 로고    scopus 로고
    • Established human papillomavirus type 16-expressing tumors are effectively eradicated following vaccination with long peptides
    • COI: 1:CAS:528:DC%2BD38XltVKis7k%3D, PID: 12077264
    • Zwaveling S, Ferreira Mota SC, Nouta J, Johnson M, Lipford GB, Offringa R, van der Burg SH, Melief CJ (2002) Established human papillomavirus type 16-expressing tumors are effectively eradicated following vaccination with long peptides. J Immunol. 169:350–358
    • (2002) J Immunol , vol.169 , pp. 350-358
    • Zwaveling, S.1    Ferreira Mota, S.C.2    Nouta, J.3    Johnson, M.4    Lipford, G.B.5    Offringa, R.6    van der Burg, S.H.7    Melief, C.J.8


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.