Ablative fractional laser alters biodistribution of ingenol mebutate in the skin

Archives of Dermatological Research

Volumn 307, Issue 6, 2015, Pages 515-522

  Erlendsson, A M ^a,b   Taudorf, E H ^a   Eriksson, A H ^c   Haak, C S ^a,b   Zibert, J R ^c   Paasch, U ^d   Anderson, R R ^b   Haedersdal, M ^a,b  

^a BISPEBJERG HOSPITAL   (Denmark)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c LEO PHARMA A S   (Denmark)

^d UNIVERSITY OF LEIPZIG   (Germany)

Author keywords

Ablative fractional laser; Actinic keratosis; Biodistribution; Drug delivery; Ingenol mebutate; Laser; Laser assisted drug delivery; Non melanoma skin cancer

Indexed keywords

INGENOL MEBUTATE; 3-INGENYL ANGELATE; DITERPENE;

ACTINIC KERATOSIS; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DERMIS; DRUG DISTRIBUTION; DRUG EFFICACY; DRUG PENETRATION; DRUG UPTAKE; EPIDERMIS; ERBIUM YAG LASER; FEMALE; LANDRACE PIG; LIQUID CHROMATOGRAPHY; MASS SPECTROMETRY; NON MELANOMA SKIN CANCER; NONHUMAN; PRIORITY JOURNAL; STRATUM CORNEUM; YORKSHIRE PIG; ANIMAL; DRUG DELIVERY SYSTEM; HUMAN; INTRADERMAL DRUG ADMINISTRATION; KERATOSIS, ACTINIC; LOW LEVEL LASER THERAPY; METABOLISM; PIG; PROCEDURES; SKIN; SKIN ABSORPTION; SOLID STATE LASER; TISSUE DISTRIBUTION;

ADMINISTRATION, CUTANEOUS; ANIMALS; CHROMATOGRAPHY, LIQUID; DITERPENES; DRUG DELIVERY SYSTEMS; HUMANS; KERATOSIS, ACTINIC; LASER THERAPY; LASERS, SOLID-STATE; MASS SPECTROMETRY; SKIN; SKIN ABSORPTION; SWINE; TISSUE DISTRIBUTION;

EID: 84937971053     PISSN: 03403696     EISSN: 1432069X     Source Type: Journal    
DOI: 10.1007/s00403-015-1561-3     Document Type: Article

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