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Volumn 34, Issue 30, 2015, Pages 3895-3907

MiR-873 regulates ERα transcriptional activity and tamoxifen resistance via targeting CDK3 in breast cancer cells

Author keywords

[No Author keywords available]

Indexed keywords

CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 3; ESTROGEN RECEPTOR ALPHA; ESTROGEN RECEPTOR BETA; MESSENGER RNA; MICRORNA; MICRORNA 873; TAMOXIFEN; UNCLASSIFIED DRUG; ANTINEOPLASTIC HORMONE AGONISTS AND ANTAGONISTS; CDK3 PROTEIN, HUMAN; ESTROGEN RECEPTOR ALPHA, HUMAN; MIRN873 MICRORNA, HUMAN;

EID: 84937969295     PISSN: 09509232     EISSN: 14765594     Source Type: Journal    
DOI: 10.1038/onc.2014.430     Document Type: Article
Times cited : (79)

References (55)
  • 1
    • 0035945656 scopus 로고    scopus 로고
    • Estrogen and the risk of breast cancer
    • Clemons M, Goss P. Estrogen and the risk of breast cancer. N Engl J Med 2001; 344: 276-285.
    • (2001) N Engl J Med , vol.344 , pp. 276-285
    • Clemons, M.1    Goss, P.2
  • 2
    • 30944469849 scopus 로고    scopus 로고
    • Estrogen carcinogenesis in breast cancer
    • Yager JD, Davidson NE. Estrogen carcinogenesis in breast cancer. N Engl J Med 2006; 354: 270-282.
    • (2006) N Engl J Med , vol.354 , pp. 270-282
    • Yager, J.D.1    Davidson, N.E.2
  • 3
    • 79960832381 scopus 로고    scopus 로고
    • The different roles of ER subtypes in cancer biology and therapy
    • Thomas C, Gustafsson JA. The different roles of ER subtypes in cancer biology and therapy. Nat Rev Cancer 2011; 11: 597-608.
    • (2011) Nat Rev Cancer , vol.11 , pp. 597-608
    • Thomas, C.1    Gustafsson, J.A.2
  • 4
    • 0035878743 scopus 로고    scopus 로고
    • Estrogen receptor interaction with estrogen response elements
    • Klinge CM. Estrogen receptor interaction with estrogen response elements. Nucleic Acids Res 2001; 29: 2905-2919.
    • (2001) Nucleic Acids Res , vol.29 , pp. 2905-2919
    • Klinge, C.M.1
  • 5
    • 34548248572 scopus 로고    scopus 로고
    • Oestrogen-receptor-mediated transcription and the influence of co-factors and chromatin state
    • Green KA, Carroll JS. Oestrogen-receptor-mediated transcription and the influence of co-factors and chromatin state. Nat Rev Cancer 2007; 7: 713-722.
    • (2007) Nat Rev Cancer , vol.7 , pp. 713-722
    • Green, K.A.1    Carroll, J.S.2
  • 6
    • 0032446607 scopus 로고    scopus 로고
    • The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen
    • Shiau AK, Barstad D, Loria PM, Cheng L, Kushner PJ, Agard DA et al. The structural basis of estrogen receptor/coactivator recognition and the antagonism of this interaction by tamoxifen. Cell 1998; 95: 927-937.
    • (1998) Cell , vol.95 , pp. 927-937
    • Shiau, A.K.1    Barstad, D.2    Loria, P.M.3    Cheng, L.4    Kushner, P.J.5    Agard, D.A.6
  • 8
    • 0037739787 scopus 로고    scopus 로고
    • Domains of estrogen receptor alpha (ERalpha) required for ERalpha/Sp1-mediated activation of GC-rich promoters by estrogens and antiestrogens in breast cancer cells
    • Kim K, Thu N, Saville B, Safe S. Domains of estrogen receptor alpha (ERalpha) required for ERalpha/Sp1-mediated activation of GC-rich promoters by estrogens and antiestrogens in breast cancer cells. Mol Endocrinol 2003; 17: 804-817.
    • (2003) Mol Endocrinol , vol.17 , pp. 804-817
    • Kim, K.1    Thu, N.2    Saville, B.3    Safe, S.4
  • 10
    • 0030946198 scopus 로고    scopus 로고
    • Coactivator and corepressor regulation of the agonist/antagonist activity of the mixed antiestrogen, 4-hydroxytamoxifen
    • Smith CL, Nawaz Z, O'Malley BW. Coactivator and corepressor regulation of the agonist/antagonist activity of the mixed antiestrogen, 4-hydroxytamoxifen. Mol Endocrinol 1997; 11: 657-666.
    • (1997) Mol Endocrinol , vol.11 , pp. 657-666
    • Smith, C.L.1    Nawaz, Z.2    O'Malley, B.W.3
  • 11
    • 0037192501 scopus 로고    scopus 로고
    • Molecular determinants for the tissue specificity of SERMs
    • Shang Y, Brown M. Molecular determinants for the tissue specificity of SERMs. Science 2002; 295: 2465-2468.
    • (2002) Science , vol.295 , pp. 2465-2468
    • Shang, Y.1    Brown, M.2
  • 13
    • 80053562371 scopus 로고    scopus 로고
    • Development of subtype-selective oestrogen receptor-based therapeutics
    • Nilsson S, Koehler KF, Gustafsson JA. Development of subtype-selective oestrogen receptor-based therapeutics. Nat Rev Drug Discov 2011; 10: 778-792.
    • (2011) Nat Rev Drug Discov , vol.10 , pp. 778-792
    • Nilsson, S.1    Koehler, K.F.2    Gustafsson, J.A.3
  • 14
    • 0037434618 scopus 로고    scopus 로고
    • Selective estrogen-receptor modulators-mechanisms of action and application to clinical practice
    • Riggs BL, Hartmann LC. Selective estrogen-receptor modulators-mechanisms of action and application to clinical practice. N Engl J Med 2003; 348: 618-629.
    • (2003) N Engl J Med , vol.348 , pp. 618-629
    • Riggs, B.L.1    Hartmann, L.C.2
  • 15
    • 19344364880 scopus 로고    scopus 로고
    • Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: An overview of the randomised trials
    • Abe O, Abe R, Enomoto K, Kikuchi K, Koyama H, Masuda H et al. Effects of chemotherapy and hormonal therapy for early breast cancer on recurrence and 15-year survival: An overview of the randomised trials. Lancet 2005; 365: 1687-1717.
    • (2005) Lancet , vol.365 , pp. 1687-1717
    • Abe, O.1    Abe, R.2    Enomoto, K.3    Kikuchi, K.4    Koyama, H.5    Masuda, H.6
  • 16
    • 84855364818 scopus 로고    scopus 로고
    • Global characterization of the SRC-1 transcriptome identifies ADAM22 as an ER-independent mediator of endocrine-resistant breast cancer
    • McCartan D, Bolger JC, Fagan A, Byrne C, Hao Y, Qin L et al. Global characterization of the SRC-1 transcriptome identifies ADAM22 as an ER-independent mediator of endocrine-resistant breast cancer. Cancer Res 2012; 72: 220-229.
    • (2012) Cancer Res , vol.72 , pp. 220-229
    • McCartan, D.1    Bolger, J.C.2    Fagan, A.3    Byrne, C.4    Hao, Y.5    Qin, L.6
  • 17
    • 0036488531 scopus 로고    scopus 로고
    • Endocrine-responsive breast cancer and strategies for combating resistance
    • Ali S, Coombes RC. Endocrine-responsive breast cancer and strategies for combating resistance. Nat Rev Cancer 2002; 2: 101-112.
    • (2002) Nat Rev Cancer , vol.2 , pp. 101-112
    • Ali, S.1    Coombes, R.C.2
  • 18
    • 2942652871 scopus 로고    scopus 로고
    • Mechanisms of tamoxifen resistance: Increased estrogen receptor-HER2/neu cross-talk in ER/ HER2-positive breast cancer
    • Shou J, Massarweh S, Osborne CK, Wakeling AE, Ali S, Weiss H et al. Mechanisms of tamoxifen resistance: increased estrogen receptor-HER2/neu cross-talk in ER/ HER2-positive breast cancer. J Natl Cancer Inst 2004; 96: 926-935.
    • (2004) J Natl Cancer Inst , vol.96 , pp. 926-935
    • Shou, J.1    Massarweh, S.2    Osborne, C.K.3    Wakeling, A.E.4    Ali, S.5    Weiss, H.6
  • 19
    • 12144269500 scopus 로고    scopus 로고
    • Crosstalk between estrogen receptor and growth factor receptor pathways as a cause for endocrine therapy resistance in breast cancer
    • Osborne CK, Shou J, Massarweh S, Schiff R. Crosstalk between estrogen receptor and growth factor receptor pathways as a cause for endocrine therapy resistance in breast cancer. Clin Cancer Res 2005; 11: 865s-870s.
    • (2005) Clin Cancer Res , vol.11 , pp. 865s-870s
    • Osborne, C.K.1    Shou, J.2    Massarweh, S.3    Schiff, R.4
  • 20
    • 79551576468 scopus 로고    scopus 로고
    • Mechanisms of endocrine resistance in breast cancer
    • Osborne CK, Schiff R. Mechanisms of endocrine resistance in breast cancer. Annu Rev Med 2011; 62: 233-247.
    • (2011) Annu Rev Med , vol.62 , pp. 233-247
    • Osborne, C.K.1    Schiff, R.2
  • 21
    • 84877091558 scopus 로고    scopus 로고
    • Bazedoxifene exhibits antiestrogenic activity in animal models of tamoxifen-resistant breast cancer: Implications for treatment of advanced disease
    • Wardell SE, Nelson ER, Chao CA, McDonnell DP. Bazedoxifene exhibits antiestrogenic activity in animal models of tamoxifen-resistant breast cancer: implications for treatment of advanced disease. Clin Cancer Res 2013; 19: 2420-2431.
    • (2013) Clin Cancer Res , vol.19 , pp. 2420-2431
    • Wardell, S.E.1    Nelson, E.R.2    Chao, C.A.3    McDonnell, D.P.4
  • 23
    • 84871346487 scopus 로고    scopus 로고
    • Clinical applications for microRNAs in cancer
    • Nana-Sinkam SP, Croce CM. Clinical applications for microRNAs in cancer. Clin Pharmacol Ther 2013; 93: 98-104.
    • (2013) Clin Pharmacol Ther , vol.93 , pp. 98-104
    • Nana-Sinkam, S.P.1    Croce, C.M.2
  • 24
    • 84878113369 scopus 로고    scopus 로고
    • The shaping and functional consequences of the microRNA landscape in breast cancer
    • Dvinge H, Git A, Graf S, Salmon-Divon M, Curtis C, Sottoriva A et al. The shaping and functional consequences of the microRNA landscape in breast cancer. Nature 2013; 497: 378-382.
    • (2013) Nature , vol.497 , pp. 378-382
    • Dvinge, H.1    Git, A.2    Graf, S.3    Salmon-Divon, M.4    Curtis, C.5    Sottoriva, A.6
  • 25
    • 84860386584 scopus 로고    scopus 로고
    • MiRNAs and estrogen action
    • Klinge CM. miRNAs and estrogen action. Trends Endocrinol Metab 2012; 23: 223-233.
    • (2012) Trends Endocrinol Metab , vol.23 , pp. 223-233
    • Klinge, C.M.1
  • 26
    • 56449092072 scopus 로고    scopus 로고
    • MicroRNA-221/222 confers tamoxifen resistance in breast cancer by targeting p27Kip1
    • Miller TE, Ghoshal K, Ramaswamy B, Roy S, Datta J, Shapiro CL et al. MicroRNA-221/222 confers tamoxifen resistance in breast cancer by targeting p27Kip1. J Biol Chem 2008; 283: 29897-29903.
    • (2008) J Biol Chem , vol.283 , pp. 29897-29903
    • Miller, T.E.1    Ghoshal, K.2    Ramaswamy, B.3    Roy, S.4    Datta, J.5    Shapiro, C.L.6
  • 27
    • 84874735111 scopus 로고    scopus 로고
    • Re-expression of microRNA-375 reverses both tamoxifen resistance and accompanying EMT-like properties in breast cancer
    • Ward A, Balwierz A, Zhang JD, Kublbeck M, Pawitan Y, Hielscher T et al. Re-expression of microRNA-375 reverses both tamoxifen resistance and accompanying EMT-like properties in breast cancer. Oncogene 2013; 32: 1173-1182.
    • (2013) Oncogene , vol.32 , pp. 1173-1182
    • Ward, A.1    Balwierz, A.2    Zhang, J.D.3    Kublbeck, M.4    Pawitan, Y.5    Hielscher, T.6
  • 28
    • 80052195502 scopus 로고    scopus 로고
    • Genome-wide profiling of chromatin signatures reveals epigenetic regulation of MicroRNA genes in colorectal cancer
    • Suzuki H, Takatsuka S, Akashi H, Yamamoto E, Nojima M, Maruyama R et al. Genome-wide profiling of chromatin signatures reveals epigenetic regulation of MicroRNA genes in colorectal cancer. Cancer Res 2011; 71: 5646-5658.
    • (2011) Cancer Res , vol.71 , pp. 5646-5658
    • Suzuki, H.1    Takatsuka, S.2    Akashi, H.3    Yamamoto, E.4    Nojima, M.5    Maruyama, R.6
  • 29
    • 80052420492 scopus 로고    scopus 로고
    • Reduced expression of brain-enriched microRNAs in glioblastomas permits targeted regulation of a cell death gene
    • Skalsky RL, Cullen BR. Reduced expression of brain-enriched microRNAs in glioblastomas permits targeted regulation of a cell death gene. PLoS ONE 2011; 6: e24248.
    • (2011) PLoS ONE , vol.6 , pp. e24248
    • Skalsky, R.L.1    Cullen, B.R.2
  • 30
    • 44349124725 scopus 로고    scopus 로고
    • Genomic and epigenetic alterations deregulate microRNA expression in human epithelial ovarian cancer
    • Zhang L, Volinia S, Bonome T, Calin GA, Greshock J, Yang N et al. Genomic and epigenetic alterations deregulate microRNA expression in human epithelial ovarian cancer. Proc Natl Acad Sci USA 2008; 105: 7004-7009.
    • (2008) Proc Natl Acad Sci USA , vol.105 , pp. 7004-7009
    • Zhang, L.1    Volinia, S.2    Bonome, T.3    Calin, G.A.4    Greshock, J.5    Yang, N.6
  • 31
    • 0030931670 scopus 로고    scopus 로고
    • Regulation of estrogen receptor transcriptional enhancement by the cyclin A/Cdk2 complex
    • Trowbridge JM, Rogatsky I, Garabedian MJ. Regulation of estrogen receptor transcriptional enhancement by the cyclin A/Cdk2 complex. Proc Natl Acad Sci USA 1997; 94: 10132-10137.
    • (1997) Proc Natl Acad Sci USA , vol.94 , pp. 10132-10137
    • Trowbridge, J.M.1    Rogatsky, I.2    Garabedian, M.J.3
  • 32
    • 54749124446 scopus 로고    scopus 로고
    • Cyclin-dependent kinase 3-mediated activating transcription factor 1 phosphorylation enhances cell transformation
    • Zheng D, Cho YY, Lau AT, Zhang J, Ma WY, Bode AM et al. Cyclin-dependent kinase 3-mediated activating transcription factor 1 phosphorylation enhances cell transformation. Cancer Res 2008; 68: 7650-7660.
    • (2008) Cancer Res , vol.68 , pp. 7650-7660
    • Zheng, D.1    Cho, Y.Y.2    Lau, A.T.3    Zhang, J.4    Ma, W.Y.5    Bode, A.M.6
  • 33
    • 79951807772 scopus 로고    scopus 로고
    • Roscovitine, a selective CDK inhibitor, reduces the basal and estrogen-induced phosphorylation of ER-alpha in human ER-positive breast cancer cells
    • Wesierska-Gadek J, Gritsch D, Zulehner N, Komina O, Maurer M. Roscovitine, a selective CDK inhibitor, reduces the basal and estrogen-induced phosphorylation of ER-alpha in human ER-positive breast cancer cells. J Cell Biochem 2011; 112: 761-772.
    • (2011) J Cell Biochem , vol.112 , pp. 761-772
    • Wesierska-Gadek, J.1    Gritsch, D.2    Zulehner, N.3    Komina, O.4    Maurer, M.5
  • 34
    • 85084273499 scopus 로고    scopus 로고
    • 76p∗a phase 1 open-label fixed-sequence two-period crossover study of the effect of multiple doses of tamoxifen on palbociclib (pd-0332991) pharmacokinetics in healthy male volunteers
    • Hoffman JT, O'Gorman M, Loi C, Plotka A, Kirkovsky L, Boutros T et al. 76p∗a phase 1 open-label fixed-sequence two-period crossover study of the effect of multiple doses of tamoxifen on palbociclib (pd-0332991) pharmacokinetics in healthy male volunteers. Ann Oncol 2014; 25(Suppl 1): i27.
    • (2014) Ann Oncol , vol.25 , pp. i27
    • Hoffman, J.T.1    O'Gorman, M.2    Loi, C.3    Plotka, A.4    Kirkovsky, L.5    Boutros, T.6
  • 35
    • 84868228009 scopus 로고    scopus 로고
    • Cross-talk between HER2 and MED1 regulates tamoxifen resistance of human breast cancer cells
    • Cui J, Germer K, Wu T, Wang J, Luo J, Wang SC et al. Cross-talk between HER2 and MED1 regulates tamoxifen resistance of human breast cancer cells. Cancer Res 2012; 72: 5625-5634.
    • (2012) Cancer Res , vol.72 , pp. 5625-5634
    • Cui, J.1    Germer, K.2    Wu, T.3    Wang, J.4    Luo, J.5    Wang, S.C.6
  • 36
    • 22344435852 scopus 로고    scopus 로고
    • Cell cycle progression stimulated by tamoxifen-bound estrogen receptor-alpha and promoter-specific effects in breast cancer cells deficient in N-CoR and SMRT
    • Keeton EK, Brown M. Cell cycle progression stimulated by tamoxifen-bound estrogen receptor-alpha and promoter-specific effects in breast cancer cells deficient in N-CoR and SMRT. Mol Endocrinol 2005; 19: 1543-1554.
    • (2005) Mol Endocrinol , vol.19 , pp. 1543-1554
    • Keeton, E.K.1    Brown, M.2
  • 37
    • 85028133025 scopus 로고    scopus 로고
    • MicroRNAs and cancer stem cells: The sword and the shield
    • Sun X, Jiao X, Pestell TG, Fan C, Qin S, Mirabelli E et al. MicroRNAs and cancer stem cells: The sword and the shield. Oncogene 2013; 33: 4967-4977.
    • (2013) Oncogene , vol.33 , pp. 4967-4977
    • Sun, X.1    Jiao, X.2    Pestell, T.G.3    Fan, C.4    Qin, S.5    Mirabelli, E.6
  • 38
    • 84879492700 scopus 로고    scopus 로고
    • MicroRNAs and drug resistance of breast cancer: Basic evidence and clinical applications
    • Tian W, Chen J, He H, Deng Y. MicroRNAs and drug resistance of breast cancer: basic evidence and clinical applications. Clin Transl Oncol 2013; 15: 335-342.
    • (2013) Clin Transl Oncol , vol.15 , pp. 335-342
    • Tian, W.1    Chen, J.2    He, H.3    Deng, Y.4
  • 39
    • 84880570961 scopus 로고    scopus 로고
    • MicroRNA-antagonism regulates breast cancer stemness and metastasis via TET-family-dependent chromatin remodeling
    • Song SJ, Poliseno L, Song MS, Ala U, Webster K, Ng C et al. MicroRNA-antagonism regulates breast cancer stemness and metastasis via TET-family-dependent chromatin remodeling. Cell 2013; 154: 311-324.
    • (2013) Cell , vol.154 , pp. 311-324
    • Song, S.J.1    Poliseno, L.2    Song, M.S.3    Ala, U.4    Webster, K.5    Ng, C.6
  • 40
    • 84855339741 scopus 로고    scopus 로고
    • Tamoxifen downregulation of miR-451 increases 14-3-3zeta and promotes breast cancer cell survival and endocrine resistance
    • Bergamaschi A, Katzenellenbogen BS. Tamoxifen downregulation of miR-451 increases 14-3-3zeta and promotes breast cancer cell survival and endocrine resistance. Oncogene 2012; 31: 39-47.
    • (2012) Oncogene , vol.31 , pp. 39-47
    • Bergamaschi, A.1    Katzenellenbogen, B.S.2
  • 41
    • 84862744909 scopus 로고    scopus 로고
    • A role for estrogen receptor phosphorylation in the resistance to tamoxifen
    • de Leeuw R, Neefjes J, Michalides R. A role for estrogen receptor phosphorylation in the resistance to tamoxifen. Int J Breast Cancer 2011; 2011: 232435.
    • (2011) Int J Breast Cancer , vol.2011 , pp. 232435
    • De Leeuw, R.1    Neefjes, J.2    Michalides, R.3
  • 42
    • 72649090647 scopus 로고    scopus 로고
    • Estrogen receptor-alpha phosphorylation at serine-118 and tamoxifen response in breast cancer
    • Kok M, Holm-Wigerup C, Hauptmann M, Michalides R, Stal O, Linn S et al. Estrogen receptor-alpha phosphorylation at serine-118 and tamoxifen response in breast cancer. J Natl Cancer Inst 2009; 101: 1725-1729.
    • (2009) J Natl Cancer Inst , vol.101 , pp. 1725-1729
    • Kok, M.1    Holm-Wigerup, C.2    Hauptmann, M.3    Michalides, R.4    Stal, O.5    Linn, S.6
  • 43
    • 16444369651 scopus 로고    scopus 로고
    • Molecular changes associated with the agonist activity of hydroxy-tamoxifen and the hyperresponse to estradiol in hydroxy-tamoxifen-resistant breast cancer cell lines
    • Vendrell JA, Bieche I, Desmetz C, Badia E, Tozlu S, Nguyen C et al. Molecular changes associated with the agonist activity of hydroxy-tamoxifen and the hyperresponse to estradiol in hydroxy-tamoxifen-resistant breast cancer cell lines. Endocr Relat Cancer 2005; 12: 75-92.
    • (2005) Endocr Relat Cancer , vol.12 , pp. 75-92
    • Vendrell, J.A.1    Bieche, I.2    Desmetz, C.3    Badia, E.4    Tozlu, S.5    Nguyen, C.6
  • 44
    • 33751101625 scopus 로고    scopus 로고
    • Phosphorylation of ER alpha at serine 118 in primary breast cancer and in tamoxifen-resistant tumours is indicative of a complex role for ER alpha phosphorylation in breast cancer progression
    • Sarwar N, Kim JS, Jiang J, Peston D, Sinnett HD, Madden P et al. Phosphorylation of ER alpha at serine 118 in primary breast cancer and in tamoxifen-resistant tumours is indicative of a complex role for ER alpha phosphorylation in breast cancer progression. Endocr-Relat Cancer 2006; 13: 851-861.
    • (2006) Endocr-Relat Cancer , vol.13 , pp. 851-861
    • Sarwar, N.1    Kim, J.S.2    Jiang, J.3    Peston, D.4    Sinnett, H.D.5    Madden, P.6
  • 45
    • 33751552134 scopus 로고    scopus 로고
    • Kinasespecific phosphorylation of the estrogen receptor changes receptor interactions with ligand, deoxyribonucleic acid, and coregulators associated with alterations in estrogen and tamoxifen activity
    • Likhite VS, Stossi F, Kim K, Katzenellenbogen BS, Katzenellenbogen JA. Kinasespecific phosphorylation of the estrogen receptor changes receptor interactions with ligand, deoxyribonucleic acid, and coregulators associated with alterations in estrogen and tamoxifen activity. Mol Endocrinol 2006; 20: 3120-3132.
    • (2006) Mol Endocrinol , vol.20 , pp. 3120-3132
    • Likhite, V.S.1    Stossi, F.2    Kim, K.3    Katzenellenbogen, B.S.4    Katzenellenbogen, J.A.5
  • 46
    • 1942421702 scopus 로고    scopus 로고
    • Cyclin C/cdk3 promotes Rb-dependent G0 exit
    • Ren S, Rollins BJ. Cyclin C/cdk3 promotes Rb-dependent G0 exit. Cell 2004; 117: 239-251.
    • (2004) Cell , vol.117 , pp. 239-251
    • Ren, S.1    Rollins, B.J.2
  • 47
    • 77954571810 scopus 로고    scopus 로고
    • CDK inhibitors as potential breast cancer therapeutics: New evidence for enhanced efficacy in ER+ disease
    • Sutherland RL, Musgrove EA. CDK inhibitors as potential breast cancer therapeutics: new evidence for enhanced efficacy in ER+ disease. Breast Cancer Res 2009; 11: 112.
    • (2009) Breast Cancer Res , vol.11 , pp. 112
    • Sutherland, R.L.1    Musgrove, E.A.2
  • 48
    • 80054752304 scopus 로고    scopus 로고
    • The CDK inhibitors in cancer research and therapy
    • Cicenas J, Valius M. The CDK inhibitors in cancer research and therapy. J Cancer Res Clin Oncol 2011; 137: 1409-1418.
    • (2011) J Cancer Res Clin Oncol , vol.137 , pp. 1409-1418
    • Cicenas, J.1    Valius, M.2
  • 49
    • 0035852699 scopus 로고    scopus 로고
    • A premature-termination mutation in the Mus musculus cyclin-dependent kinase 3 gene
    • Ye X, Zhu C, Harper JW. A premature-termination mutation in the Mus musculus cyclin-dependent kinase 3 gene. Proc Natl Acad Sci USA 2001; 98: 1682-1686.
    • (2001) Proc Natl Acad Sci USA , vol.98 , pp. 1682-1686
    • Ye, X.1    Zhu, C.2    Harper, J.W.3
  • 50
    • 84899690736 scopus 로고    scopus 로고
    • CDK3 expression and its clinical significance in human nasopharyngeal carcinoma
    • Wang L, Hu HY, Lin YL, Zhao ZX, Tan L, Yu P et al. CDK3 expression and its clinical significance in human nasopharyngeal carcinoma. Mol Med Rep 2014; 9: 2582-2586.
    • (2014) Mol Med Rep , vol.9 , pp. 2582-2586
    • Wang, L.1    Hu, H.Y.2    Lin, Y.L.3    Zhao, Z.X.4    Tan, L.5    Yu, P.6
  • 51
    • 0028923566 scopus 로고
    • Chromosomal mapping of members of the cdc2 family of protein kinases, cdk3, cdk6, PISSLRE, and PITALRE, and a cdk inhibitor, p27Kip1, to regions involved in human cancer
    • Bullrich F, MacLachlan TK, Sang N, Druck T, Veronese ML, Allen SL et al. Chromosomal mapping of members of the cdc2 family of protein kinases, cdk3, cdk6, PISSLRE, and PITALRE, and a cdk inhibitor, p27Kip1, to regions involved in human cancer. Cancer Res 1995; 55: 1199-1205.
    • (1995) Cancer Res , vol.55 , pp. 1199-1205
    • Bullrich, F.1    MacLachlan, T.K.2    Sang, N.3    Druck, T.4    Veronese, M.L.5    Allen, S.L.6
  • 52
    • 79955962062 scopus 로고    scopus 로고
    • Arginine and glutamate-rich 1 (ARGLU1) interacts with mediator subunit 1 (MED1) and is required for estrogen receptormediated gene transcription and breast cancer cell growth
    • Zhang D, Jiang P, Xu Q, Zhang X. Arginine and glutamate-rich 1 (ARGLU1) interacts with mediator subunit 1 (MED1) and is required for estrogen receptormediated gene transcription and breast cancer cell growth. J Biol Chem 2011; 286: 17746-17754.
    • (2011) J Biol Chem , vol.286 , pp. 17746-17754
    • Zhang, D.1    Jiang, P.2    Xu, Q.3    Zhang, X.4
  • 53
    • 0033637703 scopus 로고    scopus 로고
    • Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription
    • Shang YF, Hu X, DiRenzo J, Lazar MA, Brown M. Cofactor dynamics and sufficiency in estrogen receptor-regulated transcription. Cell 2000; 103: 843-852.
    • (2000) Cell , vol.103 , pp. 843-852
    • Shang, Y.F.1    Hu, X.2    DiRenzo, J.3    Lazar, M.A.4    Brown, M.5
  • 54
    • 79953712294 scopus 로고    scopus 로고
    • FBI-1 functions as a novel AR corepressor in prostate cancer cells
    • Cui J, Yang Y, Zhang C, Hu P, Kan W, Bai X et al. FBI-1 functions as a novel AR corepressor in prostate cancer cells. Cell Mol Life Sci 2011; 68: 1091-1103.
    • (2011) Cell Mol Life Sci , vol.68 , pp. 1091-1103
    • Cui, J.1    Yang, Y.2    Zhang, C.3    Hu, P.4    Kan, W.5    Bai, X.6
  • 55
    • 58249104978 scopus 로고    scopus 로고
    • Cyclin-dependent kinase-3-mediated c-Jun phosphorylation at Ser63 and Ser73 enhances cell transformation
    • Cho YY, Tang F, Yao K, Lu C, Zhu F, Zheng D et al. Cyclin-dependent kinase-3-mediated c-Jun phosphorylation at Ser63 and Ser73 enhances cell transformation. Cancer Res 2009; 69: 272-281.
    • (2009) Cancer Res , vol.69 , pp. 272-281
    • Cho, Y.Y.1    Tang, F.2    Yao, K.3    Lu, C.4    Zhu, F.5    Zheng, D.6


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