Platelet geometry sensing spatially regulates α-granule secretion to enable matrix self-deposition

Blood

Volumn 126, Issue 4, 2015, Pages 531-538

  Sakurai, Yumiko ^a,b,c,d,e   Fitch Tewfik, Jennifer L ^f   Qiu, Yongzhi ^a,b,c,d,e   Ahn, Byungwook ^a,b,c,d,e   Myers, David R ^a,b,c,d,e   Tran, Reginald ^a,b,c,d,e   Fay, Meredith E ^a,b,c,d,e   Ding, Lingmei ^c   Spearman, Paul W ^c   Michelson, Alan D ^f   Flaumenhaft, Robert ^f   Lam, Wilbur A ^a,b,c,d,e  

^a Emory University   (United States)

^b CHILDREN'S HEALTHCARE OF ATLANTA   (United States)

^c EMORY UNIVERSITY SCHOOL OF MEDICINE   (United States)

^d GEORGIA INSTITUTE OF TECHNOLOGY   (United States)

^e EMORY UNIVERSITY   (United States)

^f HARVARD MEDICAL SCHOOL   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ALPHA GRANULE; COLLAGEN; FIBRINOGEN; FIBRONECTIN; INTEGRIN; MATRIX PROTEIN; PROTEIN; RAC1 PROTEIN; UNCLASSIFIED DRUG; FIBRINOGEN RECEPTOR;

ACTIN FILAMENT; ACTIN POLYMERIZATION; ARTICLE; CELL MEMBRANE; CONTROLLED STUDY; EXOCYTOSIS; GEOMETRY; GRAY PLATELET SYNDROME; HUMAN; HUMAN CELL; PRIORITY JOURNAL; PROTEIN SECRETION; REGULATORY MECHANISM; THROMBOCYTE; THROMBOCYTE ACTIVATION; THROMBOCYTE ADHESION; WISKOTT ALDRICH SYNDROME; CASE CONTROL STUDY; CELL CULTURE; COMPARATIVE STUDY; CYTOLOGY; ENZYME IMMUNOASSAY; METABOLISM; PATHOLOGY; PHYSIOLOGY; PSEUDOPODIUM; SECRETION (PROCESS);

ACTIN CYTOSKELETON; BLOOD PLATELETS; CASE-CONTROL STUDIES; CELL MEMBRANE; CELLS, CULTURED; EXOCYTOSIS; FIBRINOGEN; FIBRONECTINS; GRAY PLATELET SYNDROME; HUMANS; IMMUNOENZYME TECHNIQUES; PLATELET ACTIVATION; PLATELET ADHESIVENESS; PLATELET GLYCOPROTEIN GPIIB-IIIA COMPLEX; PSEUDOPODIA; WISKOTT-ALDRICH SYNDROME;

EID: 84937950663     PISSN: 00064971     EISSN: 15280020     Source Type: Journal    
DOI: 10.1182/blood-2014-11-607614     Document Type: Article

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