Maternal zinc supplementation improves hepatitis B antibody responses in infants but decreases plasma zinc level

European Journal of Nutrition

Volumn 55, Issue 5, 2016, Pages 1823-1829

  Ahmad, Shaikh Meshbahuddin ^a   Hossain, Mohammad Bakhtiar ^a   Monirujjaman, Md ^a   Islam, Sharmin ^a   Huda, Md Nazmul ^a,c   Kabir, Yearul ^b   Raqib, Rubhana ^a   Lönnerdal, Bo L ^c  

^a Icddrb   (Bangladesh)

^b UNIVERSITY OF DHAKA   (Bangladesh)

^c UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

HBV; IL 7; Infant; Zinc

Indexed keywords

COPPER; HEPATITIS B ANTIBODY; HEPATITIS B SURFACE ANTIGEN; HEPATITIS B VACCINE; IMMUNOGLOBULIN G; INTERLEUKIN 7; PLACEBO; ZINC;

ADULT; ANTIBODY RESPONSE; ARTICLE; BIRTH WEIGHT; BREAST FEEDING; CESAREAN SECTION; CONTROLLED STUDY; COPPER BLOOD LEVEL; DIET SUPPLEMENTATION; DOUBLE BLIND PROCEDURE; FEMALE; GESTATIONAL AGE; HEPATITIS B; HIGH RISK INFANT; HUMAN; INFANT; MAJOR CLINICAL STUDY; MATERNAL NUTRITION; PREGNANT WOMAN; PUERPERIUM; RANDOMIZED CONTROLLED TRIAL; SECOND TRIMESTER PREGNANCY; THIRD TRIMESTER PREGNANCY; THYMUS; UMBILICAL CORD BLOOD; VACCINATION; ZINC BLOOD LEVEL; ZINC DEFICIENCY; BLOOD; DIETARY SUPPLEMENT; IMMUNOLOGY; INNATE IMMUNITY; MALE; METABOLISM; POSTNATAL CARE; PRENATAL CARE; T LYMPHOCYTE; YOUNG ADULT;

COPPER; DIETARY SUPPLEMENTS; DOUBLE-BLIND METHOD; FEMALE; HEPATITIS B; HEPATITIS B ANTIBODIES; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B VACCINES; HUMANS; IMMUNITY, INNATE; IMMUNOGLOBULIN G; INFANT; INTERLEUKIN-7; MALE; MATERNAL NUTRITIONAL PHYSIOLOGICAL PHENOMENA; POSTNATAL CARE; POSTPARTUM PERIOD; PRENATAL CARE; T-LYMPHOCYTES; YOUNG ADULT; ZINC;

EID: 84937925866     PISSN: 14366207     EISSN: 14366215     Source Type: Journal    
DOI: 10.1007/s00394-015-0999-6     Document Type: Article

References (36)

1. Sazawal S, Black RE, Jalla S, Mazumdar S, Sinha A, Bhan MK (1998) Zinc supplementation reduces the incidence of acute lower respiratory infections in infants and preschool children: a double-blind, controlled trial. Pediatrics 102(1 Pt 1):1–5
2. Black RE, Allen LH, Bhutta ZA, Caulfield LE, de Onis M, Ezzati M, Mathers C, Rivera J (2008) Maternal and child undernutrition: global and regional exposures and health consequences. Lancet 371(9608):243–260. doi:10.1016/S0140-6736(07)61690-0
3. Dijkhuizen MA, Wieringa FT, West CE, Muherdiyantiningsih Muhilal (2001) Concurrent micronutrient deficiencies in lactating mothers and their infants in Indonesia. Am J Clin Nutr 73(4):786–791
4. Dijkhuizen MA, Wieringa FT, West CE, Muhilal (2004) Zinc plus beta-carotene supplementation of pregnant women is superior to beta-carotene supplementation alone in improving vitamin A status in both mothers and infants. Am J Clin Nutr 80(5):1299–1307
5. Baylin A, Villamor E, Rifai N, Msamanga G, Fawzi WW (2005) Effect of vitamin supplementation to HIV-infected pregnant women on the micronutrient status of their infants. Eur J Clin Nutr 59(8):960–968. doi:10.1038/sj.ejcn.1602201
6. Rink L, Kirchner H (2000) Zinc-altered immune function and cytokine production. J Nutr 130(5S Suppl):1407S–1411S
7. Wieringa FT, Dijkhuizen MA, West CE, van der Ven-Jongekrijg J, van der Meer JW (2004) Reduced production of immunoregulatory cytokines in vitamin A- and zinc-deficient Indonesian infants. Eur J Clin Nutr 58(11):1498–1504. doi:10.1038/sj.ejcn.1601998
8. Brown KH, Rivera JA, Bhutta Z, Gibson RS, King JC, Lonnerdal B, Ruel MT, Sandtrom B, Wasantwisut E, Hotz C (2004) International Zinc Nutrition Consultative Group (IZiNCG) technical document #1. Assessment of the risk of zinc deficiency in populations and options for its control. Food Nutr Bull 25(1 Suppl 2):S99–S203
9. Moore JB, Blanchard RK, McCormack WT, Cousins RJ (2001) cDNA array analysis identifies thymic LCK as upregulated in moderate murine zinc deficiency before T-lymphocyte population changes. J Nutr 131(12):3189–3196
10. Apgar J (1968) Effect of zinc deficiency on parturition in the rat. Am J Physiol 215(1):160–163
11. Fraker PJ (1983) Zinc deficiency: a common immunodeficiency state. Surv Immunol Res 2(2):155–163
12. Hurley LS, Mutch PB (1973) Prenatal and postnatal development after transitory gestational zinc deficiency in rats. J Nutr 103(5):649–656
13. Beach RS, Gershwin ME, Hurley LS (1983) Persistent immunological consequences of gestation zinc deprivation. Am J Clin Nutr 38(4):579–590
14. Osendarp SJ, van Raaij JM, Darmstadt GL, Baqui AH, Hautvast JG, Fuchs GJ (2001) Zinc supplementation during pregnancy and effects on growth and morbidity in low birthweight infants: a randomised placebo controlled trial. Lancet 357(9262):1080–1085
15. Osendarp SJ, Fuchs GJ, van Raaij JM, Mahmud H, Tofail F, Black RE, Prabhakar H, Santosham M (2006) The effect of zinc supplementation during pregnancy on immune response to Hib and BCG vaccines in Bangladesh. J Trop Pediatr 52(5):316–323. doi:10.1093/tropej/fml012
16. Rink L, Gabriel P (2001) Extracellular and immunological actions of zinc. Biometals 14(3–4):367–383
17. Fraker PJ, King LE, Laakko T, Vollmer TL (2000) The dynamic link between the integrity of the immune system and zinc status. J Nutr 130(5S Suppl):1399S–1406S
18. Raqib R, Hossain MB, Kelleher SL, Stephensen CB, Lonnerdal B (2007) Zinc supplementation of pregnant rats with adequate zinc nutriture suppresses immune functions in their offspring. J Nutr 137(4):1037–1042
19. Sharkar MT, Jou MY, Hossain MB, Lonnerdal B, Stephensen CB, Raqib R (2011) Prenatal zinc supplementation of zinc-adequate rats adversely affects immunity in offspring. J Nutr 141(8):1559–1564. doi:10.3945/jn.110.129569
20. Institute of Medicine. Panel on Dietary A, Related C (2000) Dietary reference intakes for vitamin C, vitamin E, selenium, and carotenoids: A report of the Panel on Dietary Antioxidants and Related Compounds, Subcommittees on Upper Reference Levels of Nutrients and of Interpretation and Use of Dietary Reference Intakes, and the Standing Committee on the Scientific Evaluation of Dietary Reference Intakes, Food and Nutrition Board, Institute of Medicine. National Academies Press
21. Cohen J (1988) Statistical power analysis for the behavioral sciences, 2nd edn. Routledge Academic, London
22. World Health Organisation (2008) Indicators for assessing infant and young child feeding practices: part 1: definitions: conclusions of a consensus meeting held 6–8 November 2007, Washington, DC, USA
23. Wieringa FT, Dijkhuizen MA, Muhilal Van, der Meer JW (2010) Maternal micronutrient supplementation with zinc and beta-carotene affects morbidity and immune function of infants during the first 6 months of life. Eur J Clin Nutr 64(10):1072–1079. doi:10.1038/ejcn.2010.115
24. Kelly DF, Moxon ER, Pollard AJ (2004) Haemophilus influenzae type b conjugate vaccines. Immunology 113(2):163–174. doi:10.1111/j.1365-2567.2004.01971.x
25. Hotz C, Peerson JM, Brown KH (2003) Suggested lower cutoffs of serum zinc concentrations for assessing zinc status: reanalysis of the second National Health and Nutrition Examination Survey data (1976–1980). Am J Clin Nutr 78(4):756–764
26. Savy M, Edmond K, Fine PE, Hall A, Hennig BJ, Moore SE, Mulholland K, Schaible U, Prentice AM (2009) Landscape analysis of interactions between nutrition and vaccine responses in children. J Nutr 139(11):2154S–2218S. doi:10.3945/jn.109.105312
27. Qadri F, Ahmed T, Wahed MA, Ahmed F, Bhuiyan NA, Rahman AS, Clemens JD, Black RE, Albert MJ (2004) Suppressive effect of zinc on antibody response to cholera toxin in children given the killed, B subunit-whole cell, oral cholera vaccine. Vaccine 22(3–4):416–421
28. Albert MJ, Qadri F, Wahed MA, Ahmed T, Rahman AS, Ahmed F, Bhuiyan NA, Zaman K, Baqui AH, Clemens JD, Black RE (2003) Supplementation with zinc, but not vitamin A, improves seroconversion to vibriocidal antibody in children given an oral cholera vaccine. J Infect Dis 187(6):909–913. doi:10.1086/368132
29. Carrette F, Surh CD (2012) IL-7 signaling and CD127 receptor regulation in the control of T cell homeostasis. Semin Immunol 24(3):209–217. doi:10.1016/j.smim.2012.04.010
30. Zaunders JJ, Levy Y, Seddiki N (2014) Exploiting differential expression of the IL-7 receptor on memory T cells to modulate immune responses. Cytokine Growth Factor Rev 25(4):391–401. doi:10.1016/j.cytogfr.2014.07.012
31. Zapata CL, Melo MR, Donangelo CM (1997) Maternal, placental and cord zinc components in healthy women with different levels of serum zinc. Biol Neonate 72(2):84–93
32. Ford D (2004) Intestinal and placental zinc transport pathways. Proc Nutr Soc 63(1):21–29. doi:10.1079/PNS2003320
33. Helston RM, Phillips SR, McKay JA, Jackson KA, Mathers JC, Ford D (2007) Zinc transporters in the mouse placenta show a coordinated regulatory response to changes in dietary zinc intake. Placenta 28(5–6):437–444. doi:10.1016/j.placenta.2006.07.002
34. Hambidge KM, Krebs NF, Jacobs MA, Favier A, Guyette L, Ikle DN (1983) Zinc nutritional status during pregnancy: a longitudinal study. Am J Clin Nutr 37(3):429–442
35. Heinig MJ, Brown KH, Lonnerdal B, Dewey KG (2006) Zinc supplementation does not affect growth, morbidity, or motor development of US term breastfed infants at 4–10 mo of age. Am J Clin Nutr 84(3):594–601
36. Dempsey C, McCormick NH, Croxford TP, Seo YA, Grider A, Kelleher SL (2012) Marginal maternal zinc deficiency in lactating mice reduces secretory capacity and alters milk composition. J Nutr 142(4):655–660. doi:10.3945/jn.111.150623