Prenatal lipopolysaccharide exposure causes mesenteric vascular dysfunction through the nitric oxide and cyclic guanosine monophosphate pathway in offspring

Free Radical Biology and Medicine

Volumn 86, Issue , 2015, Pages 322-330

  Wang, Xinquan ^a,b   Wang, Jialiang ^a,b   Luo, Hao ^a,b   Chen, Caiyu ^a,b   Pei, Fang ^a,b   Cai, Yue ^a,b   Yang, Xiaoli ^a,b   Wang, Na ^a,b   Fu, Jinjuan ^a,b   Xu, Zaichen ^a,b   Zhou, Lin ^a,b   Zeng, Chunyu ^a,b  

^a THIRD MILITARY MEDICAL UNIVERSITY   (China)

^b Chongqing Institute of Cardiology   (China)

Author keywords

cGMP; Endothelium; Fetal programming; Hypertension; Lipopolysaccharide; Mesenteric artery; Nitric oxide; Oxidativestress

Indexed keywords

1H 1,2,4 OXADIAZOLO[4,3 A]QUINOXALIN 1 ONE; ACETYLCHOLINE; ENDOTHELIAL NITRIC OXIDE SYNTHASE; GUANOSINE PHOSPHATE; GUANYLATE CYCLASE; LIPOPOLYSACCHARIDE; N(G) NITROARGININE METHYL ESTER; NITROPRUSSIDE SODIUM; PHENYLEPHRINE; TEMPOL; CYCLIC GMP; NITRIC OXIDE;

ANIMAL EXPERIMENT; ANIMAL MODEL; ARTERY CONSTRICTION; ARTICLE; CARDIOVASCULAR FUNCTION; CONTROLLED STUDY; ENZYME INHIBITION; HYPERTENSION; IN VITRO STUDY; IN VIVO STUDY; MESENTERIC ARTERY; NONHUMAN; OXIDATIVE STRESS; PREGNANCY; PRENATAL EXPOSURE; PRIORITY JOURNAL; PROGENY; PROTEIN EXPRESSION; RAT; SIGNAL TRANSDUCTION; SPRAGUE DAWLEY RAT; VASCULAR ENDOTHELIUM; VASCULAR SMOOTH MUSCLE; VASODILATATION; ANIMAL; FEMALE; IMMUNOLOGY; METABOLISM; PATHOLOGY; SPLANCHNIC BLOOD FLOW;

RATTUS;

ANIMALS; CYCLIC GMP; ENDOTHELIUM, VASCULAR; FEMALE; HYPERTENSION; LIPOPOLYSACCHARIDES; MESENTERIC ARTERIES; NITRIC OXIDE; OXIDATIVE STRESS; PREGNANCY; PRENATAL EXPOSURE DELAYED EFFECTS; RATS, SPRAGUE-DAWLEY; SIGNAL TRANSDUCTION; SPLANCHNIC CIRCULATION; VASODILATION;

EID: 84937891839     PISSN: 08915849     EISSN: 18734596     Source Type: Journal    
DOI: 10.1016/j.freeradbiomed.2015.05.040     Document Type: Article

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