Increased cathepsin D protein expression is a biomarker for osteosarcomas, pulmonary metastases and other bone malignancies

Oncotarget

Volumn 6, Issue 18, 2015, Pages 16517-16526

  Gemoll, Timo ^a   Epping, Franziska ^a   Heinrich, Lisa ^a   Fritzsche, Britta ^a   Roblick, Uwe J ^a   Szymczak, Silke ^a   Hartwig, Sonja ^b   Depping, Reinhard ^c   Bruch, Hans Peter ^a   Thorns, Christoph ^a   Lehr, Stefan ^b   Paech, Andreas ^d   Habermann, Jens K ^a  

^a UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

^b LEIBNIZ CENTER FOR DIABETES RESEARCH AT HEINRICH HEINE UNIVERSITY DÜSSELDORF   (Germany)

^c UNIVERSITY OF LÜBECK   (Germany)

^d UNIVERSITY HOSPITAL SCHLESWIG HOLSTEIN   (Germany)

Author keywords

Bone malignancies; CTSD; Mass spectrometry; Osteosarcoma; Two dimensional gel electrophoresis

Indexed keywords

CATHEPSIN D; RAN PROTEIN; TUMOR MARKER; CTSD PROTEIN, HUMAN; NUCLEAR PROTEIN; RAN-BINDING PROTEIN 1; TUMOR PROTEIN;

AMELOBLASTOMA; ARTICLE; BONE CANCER; BONE CYST; BONE DISEASE; CHONDROSARCOMA; CHORDOMA; CONTROLLED STUDY; EWING SARCOMA; FETUS; GIANT CELL TUMOR; HUMAN; HUMAN CELL; HUMAN TISSUE; LUNG METASTASIS; MYELOMA; OSTEOBLAST; OSTEOSARCOMA; PROTEIN ANALYSIS; PROTEIN EXPRESSION; SENSITIVITY AND SPECIFICITY; BIOSYNTHESIS; BONE TUMOR; GENE EXPRESSION PROFILING; GENETICS; LUNG TUMOR; MASS SPECTROMETRY; METABOLISM; PATHOLOGY; PROTEOMICS; SECONDARY; TISSUE MICROARRAY; TUMOR CELL LINE; TWO DIMENSIONAL GEL ELECTROPHORESIS;

BIOMARKERS, TUMOR; BONE NEOPLASMS; CATHEPSIN D; CELL LINE, TUMOR; ELECTROPHORESIS, GEL, TWO-DIMENSIONAL; GENE EXPRESSION PROFILING; HUMANS; LUNG NEOPLASMS; MASS SPECTROMETRY; NEOPLASM PROTEINS; NUCLEAR PROTEINS; OSTEOBLASTS; OSTEOSARCOMA; PROTEOMICS; TISSUE ARRAY ANALYSIS;

EID: 84937834364     PISSN: None     EISSN: 19492553     Source Type: Journal    
DOI: 10.18632/oncotarget.4140     Document Type: Article

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