Making personalized health care even more personalized: Insights from activities of the IOM genomics roundtable

Annals of Family Medicine

Volumn 13, Issue 4, 2015, Pages 373-380

  David, Sean P ^a,b   Johnson, Samuel G ^b,c,d   Berger, Adam C ^c   Feero, W Gregory ^c,e   Terry, Sharon F ^b,f   Green, Larry A ^g   Phillips, Robert L ^h   Ginsburg, Geoffrey S ^b,i  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b NATIONAL ACADEMIES OF SCIENCES   (United States)

^c KAISER PERMANENTE   (United States)

^d UNIVERSITY OF COLORADO   (United States)

^e Genetic Alliance ^*  (United States)

^f GENETIC ALLIANCE   (United States)

^g UNIVERSITY OF COLORADO SCHOOL OF MEDICINE   (United States)

^h AMERICAN BOARD OF FAMILY MEDICINE   (United States)

ⁱ DUKE UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

Clinical implementation science; Genomics; Personalized medicine; Precision medicine; Primary health care

Indexed keywords

GENOMICS; HUMAN; ORGANIZATION; ORGANIZATION AND MANAGEMENT; PATIENT CARE; PERSONALIZED MEDICINE; TRANSLATIONAL RESEARCH; UNITED STATES;

GENOMICS; HUMANS; NATIONAL ACADEMIES OF SCIENCE, ENGINEERING, AND MEDICINE (U.S.) HEALTH AND MEDICINE DIVISION; PATIENT-CENTERED CARE; PRECISION MEDICINE; TRANSLATIONAL MEDICAL RESEARCH; UNITED STATES;

EID: 84937822627     PISSN: 15441709     EISSN: 15441717     Source Type: Journal    
DOI: 10.1370/afm.1772     Document Type: Article

References (44)

1. Peabody FW. The care of the patient. JAMA. 1927;88(12):877-882.
2. Centers for Disease Control and Prevention. National Ambulatory Medical Care Survey: 2010 Summary Tables. http://www.cdc.gov/ nchs/data/ahcd/namcs_summary/2010_namcs_web_tables.pdf. Published 2010.
3. Green LA, Fryer GE Jr, Yawn BP, Lanier D, Dovey SM. The ecology of medical care revisited. N Engl J Med. 2001;344(26):2021-2025.
4. Collins F. Has the revolution arrived? Nature. 2010;464(7289):674-675.
5. Institute of Medicine. Primary Care: America's Health in a New Era. Washington, DC: The National Academies Press; 1996.
6. Starfield B, Horder J. Interpersonal continuity: old and new perspectives. Br J Gen Pract. 2007;57(540):527-529.
7. Institute of Medicine. Primary Care and Public Health: Exploring Integration to Improve Population Health. Washington, DC: The National Academies Press; 2013.
8. Institute of Medicine. To Err is Human: Building a Safer Health System. Washington, DC: The National Academies Press; 2000.
9. Institute of Medicine. Crossing the Quality Chasm: A New Health System for the 21st Century. Washington, DC: The National Academies Press; 2001.
10. Martin JC, Avant RF, Bowman MA, et al. The future of family medicine: a collaborative project of the family medicine community. Ann Fam Med. 2004;3(Suppl 1):S2-S99
11. Starfield B, Shi L, Macinko J. Contribution of primary care to health systems and health. Milbank Q. 2005;83(3):457-502.
12. Crabtree BF, Nutting PA, Miller WL, Stange KC, Stewart EE, Jaén CR. Summary of the National Demonstration Project and recommendations for the patient-centered medical home. Ann Fam Med. 2010;8(Suppl_1):S80-S90;S92.
13. Baird M, Blount A, Brungardt S, et al. Joint principles: integrating behavioral health care into the patient-centered medical home. Ann Fam Med. 2014;12(2):183-185.
14. Jackson GL, Powers BJ, Chatterjee R, et al. Improving patient care. The patient centered medical home. A systematic review. Ann Intern Med. 2013;158(3):169-178.
15. Jaén CR, Ferrer RL, Miller WL, et al. Patient outcomes at 26 months in the patient-centered medical home National Demonstration Project. Ann Fam Med. 2010;8(Suppl_1):S57-S67;S92.
16. Nutting PA, Miller WL, Crabtree BF, Jaén CR, Stewart EE, Stange KC. Initial lessons from the first national demonstration project on practice transformation to a patient-centered medical home. Ann Fam Med. 2009;7(3):254-260.
17. Schwenk TL. The patient-centered medical home: one size does not fit all. JAMA. 2014;311(8):802-803.
18. Manolio TA, Chisholm RL, Ozenberger B, et al. Implementing genomic medicine in the clinic: the future is here. Genet Med. 2013;15(4):258-267.
19. Starfield B. The future of primary care: refocusing the system. N Engl J Med. 2008;359(20):2087-2091.
20. Burke W, Emery J. Genetics education for primary-care providers. Nat Rev Genet. 2002;3(7):561-566.
21. Emery J, Hayflick S. The challenge of integrating genetic medicine into primary care. BMJ. 2001;322(7293):1027-1030.
22. Laberge AM, Fryer-Edwards K, Kyler P, Lloyd-Puryear MA, Burke W. Long-term outcomes of the "Genetics in Primary Care" faculty development initiative. Fam Med. 2009;41(4):266-270.
23. Saul RA. Genetic and genomic literacy in pediatric primary care. Pediatrics. 2013;132(Suppl_3):S198-S202.
24. Burke S, Martyn M, Stone A, Bennett C, Thomas H, Farndon P. Developing a curriculum statement based on clinical practice: genetics in primary care. Br J Gen Pract. 2009;59(559):99-103.
25. Feero WG. Genomics in medicine: maturation, but not maturity. JAMA. 2013;309(14):1522-1524.
26. Harcus A. MiPCT: the nation's largest patient-centered medical home project. Mich Med. 2011;110(5):10-11.
27. Paustian ML, Alexander JA, El Reda DK, Wise CG, Green LA, Fetters MD. Partial and incremental PCMH practice transformation: implications for quality and costs. Health Serv Res. 2014;49(1):52-74.
28. Hochman ME, Asch S, Jibilian A, et al. Patient-centered medical home intervention at an internal medicine resident safety-net clinic. JAMA Intern Med. 2013;173(18):1694-1701.
29. Driscoll DL, Hiratsuka V, Johnston JM, et al. Process and outcomes of patient-centered medical care with Alaska Native people at Southcentral Foundation. Ann Fam Med. 2013;11(Suppl 1):S41-S49.
30. Reid RJ, Coleman K, Johnson EA, et al. The Group Health medical home at year two: cost savings, higher patient satisfaction, and less burnout for providers. Health Aff (Millwood). 2010;29(5):835-843.
31. US Food and Drug Administration. Table of Pharmacogenomic Biomarkers in Drug Labeling. http://www.fda.gov/Drugs/ScienceResearch/ ResearchAreas/Pharmacogenetics/ucm083378.htm. Updated Aug 18, 2014. Accessed Apr 26, 2015.
32. Institute of Medicine. Genome-based Diagnostics: Demonstrating Clinical Utility in Oncology-Workshop Summary. Washington, DC: The National Academies Press; 2013.
33. Institute of Medicine. Refining Processes for the Co-development of Genome-based Therapeutics and Companion Diagnostics-Workshop Summary. Washington, DC: The National Academies Press; 2014.
34. Feero WG, Wicklund C, Veenstra DL. The economics of genomic medicine: insights from the IOM Roundtable on Translating Genomic-Based Research for Health. JAMA. 2013;309(12):1235-1236.
35. Dewey FE, Grove ME, Pan C, et al. Clinical interpretation and implications of whole-genome sequencing. JAMA. 2014;311(10): 1035-1045.
36. Glasgow RE, Vogt TM, Boles SM. Evaluating the public health impact of health promotion interventions: the RE-AIM framework. Am J Public Health. 1999;89(9):1322-1327.
37. Grody WW, Vilain E, Nelson SF. Interpreting whole-genome sequencing. JAMA. 2014;312(3):296.
38. Emery JD, Reid G, Prevost AT, Ravine D, Walter FM. Development and validation of a family history screening questionnaire in Australian primary care. Ann Fam Med. 2014;12(3):241-249.
39. Qureshi N, Armstrong S, Dhiman P, et al; ADDFAM (Added Value of Family History in CVD Risk Assessment) Study Group. Effect of adding systematic family history enquiry to cardiovascular disease risk assessment in primary care: a matched-pair, cluster randomized trial. Ann Intern Med. 2012;156(4):253-262.
40. Qureshi N, Carroll JC, Wilson B, et al. The current state of cancer family history collection tools in primary care: a systematic review. Genet Med. 2009;11(7):495-506.
41. Rubinstein WS, Acheson LS, O'Neill SM, et al; Family Healthware Impact Trial (FHITr) Group. Clinical utility of family history for cancer screening and referral in primary care: a report from the Family Healthware Impact Trial. Genet Med. 2011;13(11):956-965.
42. Kannry JL, Williams MS. Integration of genomics into the electronic health record: mapping terra incognita. Genet Med. 2013; 15(10):757-760.
43. Houwink EJ, Sollie AW, Numans ME, Cornel MC. Proposed roadmap to stepwise integration of genetics in family medicine and clinical research. Clin Transl Med. 2013;2(1):5.
44. Collins FS, Green ED, Guttmacher AE, Guyer MS; US National Human Genome Research Institute. A vision for the future of genomics research. Nature. 2003;422(6934):835-847.