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Volumn 176-177, Issue , 2015, Pages 1-9

DNA methyltransferase expressions in Japanese rice fish (Oryzias latipes) embryogenesis is developmentally regulated and modulated by ethanol and 5-azacytidine

Author keywords

DNA methyltransferase (DNMT); Endocannabinoid receptors; Epigenetics; Ethanol; Fetal alcohol spectrum disorder (FASD); Japanese rice fish

Indexed keywords

ALCOHOL; AZACITIDINE; DNA METHYLTRANSFERASE; DNA METHYLTRANSFERASE 1; DNA METHYLTRANSFERASE 3A; DNA METHYLTRANSFERASE 3AA; DNA METHYLTRANSFERASE 3B; DNA METHYLTRANSFERASE 3BB1; ENDOCANNABINOID RECEPTOR 1A; ENDOCANNABINOID RECEPTOR 1B; MESSENGER RNA; RECEPTOR; RNA 28S; UNCLASSIFIED DRUG; CANNABINOID 1 RECEPTOR; CANNABINOID 2 RECEPTOR; DNA (CYTOSINE 5) METHYLTRANSFERASE; DNA (CYTOSINE-5-)-METHYLTRANSFERASE 1; FISH PROTEIN;

EID: 84937819600     PISSN: 15320456     EISSN: 18781659     Source Type: Journal    
DOI: 10.1016/j.cbpc.2015.07.002     Document Type: Article
Times cited : (26)

References (57)
  • 1
    • 84929484770 scopus 로고    scopus 로고
    • Sustained action of developmental ethanol exposure on the cortisol response to stress in zebrafish larvae and adults
    • M. Baiamonte, C.H. Brennan, and G.P. Vinson Sustained action of developmental ethanol exposure on the cortisol response to stress in zebrafish larvae and adults PLoS One 10 4 2015 e0124488
    • (2015) PLoS One , vol.10 , Issue.4
    • Baiamonte, M.1    Brennan, C.H.2    Vinson, G.P.3
  • 2
    • 0023472826 scopus 로고
    • CpG islands as gene markers in the vertebrate nucleus
    • A.P. Bird CpG islands as gene markers in the vertebrate nucleus Trends Genet. 3 1987 342 347
    • (1987) Trends Genet. , vol.3 , pp. 342-347
    • Bird, A.P.1
  • 3
    • 84860328637 scopus 로고    scopus 로고
    • Molecular evolution of zebrafish dnmt3 genes and thermal plasticity of their expression during embryonic development
    • C. Campos, L.M. Valente, and J.M. Fernandes Molecular evolution of zebrafish dnmt3 genes and thermal plasticity of their expression during embryonic development Gene 500 2012 93 100
    • (2012) Gene , vol.500 , pp. 93-100
    • Campos, C.1    Valente, L.M.2    Fernandes, J.M.3
  • 4
    • 84907527564 scopus 로고    scopus 로고
    • Gene-specific disruption of endocannabinoid receptor1 (cnr1a) by ethanol probably leads to the development of fetal alcohol spectrum disorder phenotypes in Japanese rice fish (Oryzias latipes) embryogenesis
    • A.K. Dasmahapatra, and I.A. Khan Gene-specific disruption of endocannabinoid receptor1 (cnr1a) by ethanol probably leads to the development of fetal alcohol spectrum disorder phenotypes in Japanese rice fish (Oryzias latipes) embryogenesis Comp. Biochem. Physiol. C Toxicol. Pharmacol. 167 2015 90 100
    • (2015) Comp. Biochem. Physiol. C Toxicol. Pharmacol. , vol.167 , pp. 90-100
    • Dasmahapatra, A.K.1    Khan, I.A.2
  • 6
    • 0020691774 scopus 로고
    • DNA methylation and gene activity
    • W. Doerfler DNA methylation and gene activity Annu. Rev. Biochem. 52 1983 93 124
    • (1983) Annu. Rev. Biochem. , vol.52 , pp. 93-124
    • Doerfler, W.1
  • 8
    • 0025738978 scopus 로고
    • Ethanol consumption inhibits fetal DNA methylation in mice: implications for fetal alcohol syndrome
    • A.J. Garro, D.L. Mcbeth, V. Lima, and C.S. Lieber Ethanol consumption inhibits fetal DNA methylation in mice: implications for fetal alcohol syndrome Alcohol. Clin. Exp. Res. 15 1991 395 398
    • (1991) Alcohol. Clin. Exp. Res. , vol.15 , pp. 395-398
    • Garro, A.J.1    Mcbeth, D.L.2    Lima, V.3    Lieber, C.S.4
  • 9
    • 84865357792 scopus 로고    scopus 로고
    • Feasibility of medaka (Oryzias latipes) as an animal model to study fetal alcohol spectrum disorder
    • J.C. Fishbein, J.M. Hillman, Elsevier Amsterdam (Chapter 3)
    • M.H. Haron, D. Powe, I.A. Khan, and A.K. Dasmahapatra Feasibility of medaka (Oryzias latipes) as an animal model to study fetal alcohol spectrum disorder J.C. Fishbein, J.M. Hillman, Adv. Mol. Toxicol. vol. 6 2012 Elsevier Amsterdam 77 128 (Chapter 3)
    • (2012) Adv. Mol. Toxicol. , vol.6 , pp. 77-128
    • Haron, M.H.1    Powe, D.2    Khan, I.A.3    Dasmahapatra, A.K.4
  • 11
    • 70149095265 scopus 로고    scopus 로고
    • Fetal alcohol spectrum disorder: the epigenetic perspective
    • P.C. Haycock Fetal alcohol spectrum disorder: the epigenetic perspective Biol. Reprod. 81 2009 607 617
    • (2009) Biol. Reprod. , vol.81 , pp. 607-617
    • Haycock, P.C.1
  • 12
    • 9144256125 scopus 로고    scopus 로고
    • The Dnmt1 DNA-(cytosine-C5)-methyltransferase methylates DNA processively with high preference for hemimethylated target sites
    • A. Hermann, R. Goyal, and A. Jeltsch The Dnmt1 DNA-(cytosine-C5)-methyltransferase methylates DNA processively with high preference for hemimethylated target sites J. Biol. Chem. 279 2004 48350 48359
    • (2004) J. Biol. Chem. , vol.279 , pp. 48350-48359
    • Hermann, A.1    Goyal, R.2    Jeltsch, A.3
  • 13
    • 77956306367 scopus 로고    scopus 로고
    • Ethanol-induced methylation of cell cycle genes in neural stem cells
    • S.D. Hicks, F.A. Middleton, and M.W. Miller Ethanol-induced methylation of cell cycle genes in neural stem cells J. Neurochem. 114 2010 1767 1780
    • (2010) J. Neurochem. , vol.114 , pp. 1767-1780
    • Hicks, S.D.1    Middleton, F.A.2    Miller, M.W.3
  • 14
    • 0029057507 scopus 로고
    • Apoptosis in the central nervous system of developing mouse fetuses from 5-azacytidine-administered dams
    • M.M. Hossain, H. Nakayama, and N. Goto Apoptosis in the central nervous system of developing mouse fetuses from 5-azacytidine-administered dams Toxicol. Pathol. 23 1995 367 372
    • (1995) Toxicol. Pathol. , vol.23 , pp. 367-372
    • Hossain, M.M.1    Nakayama, H.2    Goto, N.3
  • 15
    • 70249145741 scopus 로고    scopus 로고
    • Ethanol disrupts chondrification of the neurocranial cartilages in medaka embryos without affecting aldehyde dehydrogenase 1A2 (Aldh1A2) promoter methylation
    • Y. Hu, K.W. Willett, I.A. Khan, and B.E. Scheffler Ethanol disrupts chondrification of the neurocranial cartilages in medaka embryos without affecting aldehyde dehydrogenase 1A2 (Aldh1A2) promoter methylation Comp. Biochem. Physiol. C Toxicol. Pharmacol. 150 2009 2009 495 502
    • (2009) Comp. Biochem. Physiol. C Toxicol. Pharmacol. , vol.150 , Issue.2009 , pp. 495-502
    • Hu, Y.1    Willett, K.W.2    Khan, I.A.3    Scheffler, B.E.4
  • 16
    • 33745628063 scopus 로고    scopus 로고
    • Targeted reduction of the DNA methylation level with 5-azacytidine promotes excision of the medaka fish Tol2 transposable element
    • A. Iida, A. Shimada, A. Shima, N. Takamatsu, H. Hori, K. Takeucji, and A. Koga Targeted reduction of the DNA methylation level with 5-azacytidine promotes excision of the medaka fish Tol2 transposable element Gent. Res. Camb. 87 2006 187 193
    • (2006) Gent. Res. Camb. , vol.87 , pp. 187-193
    • Iida, A.1    Shimada, A.2    Shima, A.3    Takamatsu, N.4    Hori, H.5    Takeucji, K.6    Koga, A.7
  • 17
    • 3042631471 scopus 로고    scopus 로고
    • Stages of normal development in the medaka Oryzias latipes
    • T. Iwamatsu Stages of normal development in the medaka Oryzias latipes Mech. Dev. 121 2004 605 618
    • (2004) Mech. Dev. , vol.121 , pp. 605-618
    • Iwamatsu, T.1
  • 18
    • 84911381380 scopus 로고    scopus 로고
    • Transient exposure to ethanol during zebrafish embryogenesis results in defects in neuronal differentiation: an alternative model system to study FASD
    • X. Joya, O. Garcia-Algar, O. Vall, and C. Pujades Transient exposure to ethanol during zebrafish embryogenesis results in defects in neuronal differentiation: an alternative model system to study FASD PLoS One 9 11 2014 e112852
    • (2014) PLoS One , vol.9 , Issue.11
    • Joya, X.1    Garcia-Algar, O.2    Vall, O.3    Pujades, C.4
  • 20
    • 84945303832 scopus 로고    scopus 로고
    • Zebrafish as a model to study the role of DNA methylation in environmental toxicology
    • J.H. Kamstra, P. Alestrom, J.M. Kooter, and J. Legler Zebrafish as a model to study the role of DNA methylation in environmental toxicology Environ. Sci. Pollut. Res. 2014 10.1007/s11356-014-3466-7
    • (2014) Environ. Sci. Pollut. Res.
    • Kamstra, J.H.1    Alestrom, P.2    Kooter, J.M.3    Legler, J.4
  • 21
    • 34247368534 scopus 로고    scopus 로고
    • Epigenetics in development
    • J.C. Kiefer Epigenetics in development Dev. Dyn. 236 2007 1144 1156
    • (2007) Dev. Dyn. , vol.236 , pp. 1144-1156
    • Kiefer, J.C.1
  • 24
    • 73449131530 scopus 로고    scopus 로고
    • Alcohol exposure alters DNA methylation profile in mouse embryos at early neurulation
    • Y. Liu, Y. Balaraman, G. Wang, K.P. Nephew, and F.C. Zhou Alcohol exposure alters DNA methylation profile in mouse embryos at early neurulation Epigenetics 4 2009 500 511
    • (2009) Epigenetics , vol.4 , pp. 500-511
    • Liu, Y.1    Balaraman, Y.2    Wang, G.3    Nephew, K.P.4    Zhou, F.C.5
  • 25
    • 70149086044 scopus 로고    scopus 로고
    • Prevalence and epidemiologic characteristics of FASD from various research methods with an emphasis on recent in-school studies
    • P.A. May, J.P. Gossage, W.O. Kalberg, L.K. Robinson, D. Buckley, M. Manning, and H.E. Hoyme Prevalence and epidemiologic characteristics of FASD from various research methods with an emphasis on recent in-school studies Dev. Disabil. Res. Rev. 15 2009 176 192
    • (2009) Dev. Disabil. Res. Rev. , vol.15 , pp. 176-192
    • May, P.A.1    Gossage, J.P.2    Kalberg, W.O.3    Robinson, L.K.4    Buckley, D.5    Manning, M.6    Hoyme, H.E.7
  • 26
    • 0036947985 scopus 로고    scopus 로고
    • Variations in DNA (cytosine-5) methyltransferase-1 expression during oogenesis and early development of the zebrafish
    • A.A. Mhanni, and R.A. McGowan Variations in DNA (cytosine-5) methyltransferase-1 expression during oogenesis and early development of the zebrafish Dev. Genes Evol. 212 2002 530 533
    • (2002) Dev. Genes Evol. , vol.212 , pp. 530-533
    • Mhanni, A.A.1    McGowan, R.A.2
  • 27
    • 4544291383 scopus 로고    scopus 로고
    • Global changes in genomic methylation levels during early development of the zebrafish embryo
    • A.A. Mhanni, and R.A. McGowan Global changes in genomic methylation levels during early development of the zebrafish embryo Dev. Genes Evol. 214 2004 412 417
    • (2004) Dev. Genes Evol. , vol.214 , pp. 412-417
    • Mhanni, A.A.1    McGowan, R.A.2
  • 30
    • 84906235060 scopus 로고    scopus 로고
    • Fetal alcohol spectrum disorders and their transmission through genetic and epigenetic mechanisms
    • E.A. Mead, and D.K. Sarkar Fetal alcohol spectrum disorders and their transmission through genetic and epigenetic mechanisms Front. Genet. 5 2014 1 10 (Article 154)
    • (2014) Front. Genet. , vol.5 , pp. 1-10
    • Mead, E.A.1    Sarkar, D.K.2
  • 31
    • 84874522953 scopus 로고    scopus 로고
    • Alcohol modulates expression of DNA methyltransferases and methyl CpG-/CpG domain-binding proteins in murine embryonic fibroblasts
    • P. Mukhopadhyay, F. Rezzoug, J. Kaikaus, R.M. Greene, and M.M. Pisano Alcohol modulates expression of DNA methyltransferases and methyl CpG-/CpG domain-binding proteins in murine embryonic fibroblasts Reprod. Toxicol. 37 2013 40 48
    • (2013) Reprod. Toxicol. , vol.37 , pp. 40-48
    • Mukhopadhyay, P.1    Rezzoug, F.2    Kaikaus, J.3    Greene, R.M.4    Pisano, M.M.5
  • 32
    • 84922672989 scopus 로고    scopus 로고
    • CB1-receptor knockout neonatal mice are protected against ethanol-induced impairments of DNMT1, DNMT3A, and DNA methylation
    • N.N. Nagre, S. Subbanna, M. Shivakumar, D. Psychoyos, and B.S. Basavarajappa CB1-receptor knockout neonatal mice are protected against ethanol-induced impairments of DNMT1, DNMT3A, and DNA methylation J. Neurochem. 132 2015 429 442
    • (2015) J. Neurochem. , vol.132 , pp. 429-442
    • Nagre, N.N.1    Subbanna, S.2    Shivakumar, M.3    Psychoyos, D.4    Basavarajappa, B.S.5
  • 33
    • 47149100122 scopus 로고    scopus 로고
    • Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses
    • T.F. Oberlander, J. Weinberg, M. Papsdorf, R. Grunau, S. Misri, and A.M. Devlin Prenatal exposure to maternal depression, neonatal methylation of human glucocorticoid receptor gene (NR3C1) and infant cortisol stress responses Epigenetics 3 2008 97 106
    • (2008) Epigenetics , vol.3 , pp. 97-106
    • Oberlander, T.F.1    Weinberg, J.2    Papsdorf, M.3    Grunau, R.4    Misri, S.5    Devlin, A.M.6
  • 34
    • 0033615717 scopus 로고    scopus 로고
    • DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development
    • M. Okano, D.W. Bell, D.A. Haber, and E. Li DNA methyltransferases Dnmt3a and Dnmt3b are essential for de novo methylation and mammalian development Cell 99 1999 247 257
    • (1999) Cell , vol.99 , pp. 247-257
    • Okano, M.1    Bell, D.W.2    Haber, D.A.3    Li, E.4
  • 35
    • 69249083264 scopus 로고    scopus 로고
    • Effect of alcohol consumption on CpG methylation in the differentially methylated regions of H19 and IG-DMR in male gamates: implications or fetal alcohol spectrum disorders
    • L.A. Ouko, K. Shantikumar, J. Knezovich, P. Haycock, D.J. Schnugh, and M. Ramsay Effect of alcohol consumption on CpG methylation in the differentially methylated regions of H19 and IG-DMR in male gamates: implications or fetal alcohol spectrum disorders Alcohol. Clin. Exp. Res. 33 2009 1615 1627
    • (2009) Alcohol. Clin. Exp. Res. , vol.33 , pp. 1615-1627
    • Ouko, L.A.1    Shantikumar, K.2    Knezovich, J.3    Haycock, P.4    Schnugh, D.J.5    Ramsay, M.6
  • 36
    • 43649105135 scopus 로고    scopus 로고
    • Brain chromatin remodeling. a novel mechanism of alcoholism
    • S.C. Pandey, R. Ugale, H. Zhang, L. Tang, and A. Prakash Brain chromatin remodeling. a novel mechanism of alcoholism J. Neurosci. 28 2008 3729 3737
    • (2008) J. Neurosci. , vol.28 , pp. 3729-3737
    • Pandey, S.C.1    Ugale, R.2    Zhang, H.3    Tang, L.4    Prakash, A.5
  • 38
    • 77649286162 scopus 로고    scopus 로고
    • The site specific demethylation in the 5′-regulatory area of NMDA receptor 2B subunit gene associated with CIE-induced up-regulation of transcription
    • M. Qiang, A. Denny, J. Chen, M.K. Ticku, B. Yan, and G. Henderson The site specific demethylation in the 5′-regulatory area of NMDA receptor 2B subunit gene associated with CIE-induced up-regulation of transcription PLoS One 2010 E8798
    • (2010) PLoS One
    • Qiang, M.1    Denny, A.2    Chen, J.3    Ticku, M.K.4    Yan, B.5    Henderson, G.6
  • 40
    • 70350148422 scopus 로고    scopus 로고
    • Chromatin regulation in drug addiction and depression
    • W. Renthal, and E.J. Nestler Chromatin regulation in drug addiction and depression Dialogues Clin. Neurosci. 11 2009 257 268
    • (2009) Dialogues Clin. Neurosci. , vol.11 , pp. 257-268
    • Renthal, W.1    Nestler, E.J.2
  • 41
    • 20444467726 scopus 로고    scopus 로고
    • Fetal alcohol spectrum disorders: an overview with emphasis on changes in brain and behavior
    • E.P. Riley, and C.L. McGee Fetal alcohol spectrum disorders: an overview with emphasis on changes in brain and behavior Exp. Biol. Med. 230 2005 357 365
    • (2005) Exp. Biol. Med. , vol.230 , pp. 357-365
    • Riley, E.P.1    McGee, C.L.2
  • 43
    • 0037068372 scopus 로고    scopus 로고
    • DNA methylation and chromatin-unraveling the tangled web
    • K.D. Robertson DNA methylation and chromatin-unraveling the tangled web Oncogene 21 2002 5361 5379
    • (2002) Oncogene , vol.21 , pp. 5361-5379
    • Robertson, K.D.1
  • 45
    • 0020582853 scopus 로고
    • On the mechanism of inhibition of DNA cytosine methyltransferases by cytosine analogs
    • D.V. Santi, C.E. Garratt, and P.J. Barr On the mechanism of inhibition of DNA cytosine methyltransferases by cytosine analogs Cell 33 1983 9 10
    • (1983) Cell , vol.33 , pp. 9-10
    • Santi, D.V.1    Garratt, C.E.2    Barr, P.J.3
  • 46
    • 74049130225 scopus 로고    scopus 로고
    • Solving the Dnm2 enigma
    • M. Schaefer, and F. Lyko Solving the Dnm2 enigma Chromosoma 119 2010 35 40
    • (2010) Chromosoma , vol.119 , pp. 35-40
    • Schaefer, M.1    Lyko, F.2
  • 48
    • 0033564902 scopus 로고    scopus 로고
    • DNA methylation
    • R. Singal, and G.D. Ginder DNA methylation Blood 93 1999 4059 4070
    • (1999) Blood , vol.93 , pp. 4059-4070
    • Singal, R.1    Ginder, G.D.2
  • 49
    • 79953268825 scopus 로고    scopus 로고
    • Expression of the dnmt3 genes in zebrafish development: similarity to Dnmt3a and Dnmt3b
    • T.H.L. Smith, T.M. Collins, and R.A. McGowan Expression of the dnmt3 genes in zebrafish development: similarity to Dnmt3a and Dnmt3b Dev. Genes Evol. 220 2011 347 353
    • (2011) Dev. Genes Evol. , vol.220 , pp. 347-353
    • Smith, T.H.L.1    Collins, T.M.2    McGowan, R.A.3
  • 50
    • 0026523796 scopus 로고
    • Mechanism of human methyl-directed DNA methyltransferase and the fidelity of cytosine methylation
    • S.S. Smith, B.E. Kaplan, L.C. Sowers, and E.M. Newman Mechanism of human methyl-directed DNA methyltransferase and the fidelity of cytosine methylation Proc. Natl. Acad. Sci. U. S. A. 89 1992 4744 4748
    • (1992) Proc. Natl. Acad. Sci. U. S. A. , vol.89 , pp. 4744-4748
    • Smith, S.S.1    Kaplan, B.E.2    Sowers, L.C.3    Newman, E.M.4
  • 51
    • 84896820523 scopus 로고    scopus 로고
    • Expression patterns of dnmt3aa, dnmt3ab, and dnmt4 during development and fin regeneration in zebrafish
    • K. Takayama, N. Shimoda, S. Takanaga, S. Hozumi, and Y. Kikuchi Expression patterns of dnmt3aa, dnmt3ab, and dnmt4 during development and fin regeneration in zebrafish Gene Expr. Patter. 14 2014 105 110
    • (2014) Gene Expr. Patter. , vol.14 , pp. 105-110
    • Takayama, K.1    Shimoda, N.2    Takanaga, S.3    Hozumi, S.4    Kikuchi, Y.5
  • 52
    • 68949217876 scopus 로고    scopus 로고
    • Potential of DNMT and its epigenetic regulation for lung cancer therapy
    • M. Tang, W. Xu, Q. Wang, W. Xiao, and R. Xu Potential of DNMT and its epigenetic regulation for lung cancer therapy Curr. Genomics 10 2009 336 352
    • (2009) Curr. Genomics , vol.10 , pp. 336-352
    • Tang, M.1    Xu, W.2    Wang, Q.3    Xiao, W.4    Xu, R.5
  • 53
    • 0036897974 scopus 로고    scopus 로고
    • Absence of global genomic cytosine methylation pattern erasure during medaka (Oryzias latipes) early embryo development
    • R.B. Walter, H.Y. Li, G.W. Intano, S. Kazianis, and C.A. Walter Absence of global genomic cytosine methylation pattern erasure during medaka (Oryzias latipes) early embryo development Comp. Biochem. Physiol. B Biochem. Mol. Biol. 133 2002 597 607
    • (2002) Comp. Biochem. Physiol. B Biochem. Mol. Biol. , vol.133 , pp. 597-607
    • Walter, R.B.1    Li, H.Y.2    Intano, G.W.3    Kazianis, S.4    Walter, C.A.5
  • 54
    • 77955679883 scopus 로고    scopus 로고
    • Teratogenic effects of blue cohosh (Caulophyllum thalictroides) in Japanese medaka (Oryzias latipes) are probably mediated through GATA2/EDN1 signaling pathway
    • M. Wu, Y. Hu, Z. Ali, I.A. Khan, A.J. Verlangeiri, and A.K. Dasmahapatra Teratogenic effects of blue cohosh (Caulophyllum thalictroides) in Japanese medaka (Oryzias latipes) are probably mediated through GATA2/EDN1 signaling pathway Chem. Res. Toxicol. 23 2010 1405 1416
    • (2010) Chem. Res. Toxicol. , vol.23 , pp. 1405-1416
    • Wu, M.1    Hu, Y.2    Ali, Z.3    Khan, I.A.4    Verlangeiri, A.J.5    Dasmahapatra, A.K.6
  • 55
    • 84858795894 scopus 로고    scopus 로고
    • Valproate-induced teratogenesis in Japanese rice fish (Oryzias latipes) embryogenesis
    • M. Wu, I.A. Khan, and A.K. Dasmahapatra Valproate-induced teratogenesis in Japanese rice fish (Oryzias latipes) embryogenesis Comp. Biochem. Physiol. C Toxicol. Pharmacol. 155 2012 528 537
    • (2012) Comp. Biochem. Physiol. C Toxicol. Pharmacol. , vol.155 , pp. 528-537
    • Wu, M.1    Khan, I.A.2    Dasmahapatra, A.K.3
  • 56
    • 0028596597 scopus 로고
    • 5-Azacytidine changes gene expression and causes developmental arrest of early chick embryo
    • N. Zagris, and T. Podimatas 5-Azacytidine changes gene expression and causes developmental arrest of early chick embryo Int. J. Dev. Biol. 38 1994 741 749
    • (1994) Int. J. Dev. Biol. , vol.38 , pp. 741-749
    • Zagris, N.1    Podimatas, T.2
  • 57
    • 79961135015 scopus 로고    scopus 로고
    • Cellular DNA methylation program during neurulation and its alteration by alcohol exposure
    • F.C. Zhou, Y. Chen, and A. Love Cellular DNA methylation program during neurulation and its alteration by alcohol exposure Birth Defects Res. A Clin. Mol. Teratol. 91 2011 703 715
    • (2011) Birth Defects Res. A Clin. Mol. Teratol. , vol.91 , pp. 703-715
    • Zhou, F.C.1    Chen, Y.2    Love, A.3


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