Capillaries in the olfactory bulb but not the cortex are highly susceptible to virus-induced vascular leak and promote viral neuroinvasion

Acta Neuropathologica

Volumn 130, Issue 2, 2015, Pages 233-245

  Winkler, Clayton W ^a   Race, Brent ^a   Phillips, Katie ^a   Peterson, Karin E ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

Blood brain barrier; Brain capillary endothelial cells; Bunyavirus; Neuroinvasion; Olfactory bulb; Olfactory sensory neurons

Indexed keywords

RHO GUANINE NUCLEOTIDE BINDING PROTEIN; BACTERIAL PROTEIN; PHOTOPROTEIN; YELLOW FLUORESCENT PROTEIN, BACTERIA;

ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD BRAIN BARRIER; BRAIN CAPILLARY ENDOTHELIAL CELL; BRAIN CORTEX; BUNYAVIRIDAE; CALIFORNIA ENCEPHALITIS; CAPILLARY LEAK SYNDROME; CONTROLLED STUDY; LA CROSSE VIRUS; MOUSE; NERVE FIBER TRANSPORT; NONHUMAN; OLFACTORY BULB; OLFACTORY BULBECTOMY; OLFACTORY NUCLEUS; OLFACTORY TRACT; PATHOGENESIS; PRIORITY JOURNAL; PROTEIN EXPRESSION; SENSORY NERVE CELL; VIRAL NEUROINVASION; ANIMAL; C57BL MOUSE; CAPILLARY; CAPILLARY PERMEABILITY; CYTOSKELETON; DISEASE MODEL; GENETICS; METABOLISM; PATHOGENICITY; PATHOLOGY; PHYSIOLOGY; TRANSGENIC MOUSE; VASCULARIZATION; VIROLOGY; VIRUS ENTRY; VIRUS LOAD;

ANIMALS; BACTERIAL PROTEINS; CAPILLARIES; CAPILLARY PERMEABILITY; CEREBRAL CORTEX; CYTOSKELETON; DISEASE MODELS, ANIMAL; ENCEPHALITIS, CALIFORNIA; LA CROSSE VIRUS; LUMINESCENT PROTEINS; MICE, INBRED C57BL; MICE, TRANSGENIC; OLFACTORY BULB; VIRAL LOAD; VIRUS INTERNALIZATION;

EID: 84937813182     PISSN: 00016322     EISSN: 14320533     Source Type: Journal    
DOI: 10.1007/s00401-015-1433-0     Document Type: Article

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