Early Antidepressant Treatment and All-Cause 30-Day Mortality in Patients with Ischemic Stroke

Cerebrovascular Diseases

Volumn 40, Issue 1-2, 2015, Pages 81-90

  Mortensen, Janne Kaergaard ^a   Johnsen, Søren Paaske ^a   Larsson, Heidi ^a   Andersen, Grethe ^a  

^a AARHUS UNIVERSITY HOSPITAL   (Denmark)

Author keywords

Antidepressants; Mortality; Selective serotonin reuptake inhibitors; Stroke

Indexed keywords

ANTIDEPRESSANT AGENT; NEUROPROTECTIVE AGENT;

ADULT; AGED; ARTICLE; BRAIN ISCHEMIA; COMORBIDITY; DISEASE REGISTRY; DISEASE SEVERITY; DRUG USE; FEMALE; FOLLOW UP; HOSPITAL ADMISSION; HUMAN; MAJOR CLINICAL STUDY; MALE; MEDICAL INFORMATION; MORTALITY; PATIENT IDENTIFICATION; PRIORITY JOURNAL; STROKE PATIENT; CAUSE OF DEATH; DENMARK; DEPRESSION; MIDDLE AGED; MULTIVARIATE ANALYSIS; ODDS RATIO; PROPENSITY SCORE; PSYCHOLOGY; REGISTER; RISK FACTOR; SEVERITY OF ILLNESS INDEX; STATISTICAL MODEL; STROKE; TIME FACTOR; TREATMENT OUTCOME; VERY ELDERLY; YOUNG ADULT;

ADULT; AGED; AGED, 80 AND OVER; ANTIDEPRESSIVE AGENTS; BRAIN ISCHEMIA; CAUSE OF DEATH; COMORBIDITY; DENMARK; DEPRESSION; FEMALE; HUMANS; LOGISTIC MODELS; MALE; MIDDLE AGED; MULTIVARIATE ANALYSIS; NEUROPROTECTIVE AGENTS; ODDS RATIO; PROPENSITY SCORE; REGISTRIES; RISK FACTORS; SEVERITY OF ILLNESS INDEX; STROKE; TIME FACTORS; TREATMENT OUTCOME; YOUNG ADULT;

EID: 84937776973     PISSN: 10159770     EISSN: 14219786     Source Type: Journal    
DOI: 10.1159/000435819     Document Type: Article

References (30)

1. Ayerbe L, Ayis S, Wolfe CD, Rudd AG: Natural history, predictors and outcomes of depression after stroke: systematic review and meta-analysis. Br J Psychiatry 2013; 202: 14-21
2. Bartoli F, Lillia N, Lax A, Crocamo C, Mantero V, Carrà G, Agostoni E, Clerici M: Depression after stroke and risk of mortality: a systematic review and meta-analysis. Stroke Res Treat 2013; 2013: 862978
3. Ahmed A, Simmons Z: Pseudobulbar affect: prevalence and management. Ther Clin Risk Manag 2013; 9: 483-489
4. Hackett ML, Yang M, Anderson CS, Horrocks JA, House A: Pharmaceutical interventions for emotionalism after stroke. Cochrane Database Syst Rev 2010; 2:CD003690
5. Hackett ML, Anderson CS, House A, Halteh C: Interventions for preventing depression after stroke. Cochrane Database Syst Rev 2008; 3:CD003689
6. Andersen G, Vestergaard K, Lauritzen L: Effective treatment of poststroke depression with the selective serotonin reuptake inhibitor citalopram. Stroke 1994; 25: 1099-1104
7. Andersen G, Vestergaard K, Riis JO: Citalopram for post-stroke pathological crying. Lancet 1993; 342: 837-839
8. Mortensen JK, Larsson H, Johnsen SP, Andersen G: Post stroke use of selective serotonin reuptake inhibitors and clinical outcome among patients with ischemic stroke: a nationwide propensity score-matched follow-up study. Stroke 2013; 44: 420-426
9. Jorge RE, Robinson RG, Arndt S, Starkstein S: Mortality and poststroke depression: a placebo-controlled trial of antidepressants. Am J Psychiatry 2003; 160: 1823-1829
10. Ried LD, Jia H, Feng H, Cameon R, Wang X, Tueth M, Wu SS: Selective serotonin reuptake inhibitor treatment and depression are associated with poststroke mortality. Ann Pharmacother 2011; 45: 888-897
11. Ayerbe L, Ayis S, Crichton SL, Rudd AG, Wolfe CD: Explanatory factors for the increased mortality of stroke patients withdepression. Neurology 2014; 83: 2007-2012
12. Mortensen JK, Larsson H, Johnsen SP, Andersen G: Post stroke use of selective serotonin reuptake inhibitors and clinical outcome among patients with ischemic stroke: a nationwide propensity score-matched follow-up study. Stroke 2013; 44: 420-426
13. Chollet F, Tardy J, Albucher JF, Thalamas C, Berard E, Lamy C, Bejot Y, Deltour S, Jaillard A, Niclot P, Guillon B, Moulin T, Marque P, Pariente J, Arnaud C, Loubinoux I: Fluoxetine for motor recovery after acute ischaemic stroke (FLAME): a randomised placebo-controlled trial. Lancet Neurol 2011; 10: 123-130
14. Mead GE, Hsieh CF, Lee R, Kutlubaev M, Claxton A, Hankey GJ, Hackett M: Selective serotonin reuptake inhibitors for stroke recovery: a systematic review and meta-analysis. Stroke 2013; 44: 844-850
15. Mortensen JK, Larsson H, Johnsen SP, Andersen G: Impact of prestroke selective serotonin reuptake inhibitor treatment on stroke severity and mortality. Stroke 2014; 45: 2121-2123
16. Mainz J, Krog BR, Bjørnshave B, Bartels P: Nationwide continuous quality improvement using clinical indicators the Danish National Indicator Project. Int J Qual Health Care 2004; 16(suppl 1):i45-i50
17. Pedersen CB, Gøtzsche H, Møller JO, Mortensen PB: The Danish Civil Registration System. A cohort of eight million persons. Dan Med Bull 2006; 53: 441-449
18. Kildemoes HW, Sørensen HT, Hallas J: The Danish National Prescription Registry. Scand J Public Health 2011; 39(7 suppl):38-41
19. Andersen TF, Madsen M, Jørgensen J, Mellemkjoer L, Olsen JH: The Danish National Hospital Register. A valuable source of data for modern health sciences. Dan Med Bull 1999; 46: 263-268
20. Langagergaard V, Palnum KH, Mehnert F, Ingeman A, Krogh BR, Bartels P, Johnsen SP: Socioeconomic differences in quality of care and clinical outcome after stroke: a nationwide population-based study. Stroke 2011; 42: 2896-2902
21. Charlson ME, Pompei P, Ales KL, MacKenzie CR: A new method of classifying prognostic comorbidity in longitudinal studies: development and validation. J Chronic Dis 1987; 40: 373-383
22. Brookhart MA, Schneeweiss S, Rothman KJ, Glynn RJ, Avorn J, Stürmer T: Variable selection for propensity score models. Am J Epidemiol 2006; 163: 1149-1156
23. Austin PC: Optimal caliper widths for propensity-score matching when estimating differences in means and differences in proportions in observational studies. Pharm Stat 2011; 10: 150-161
24. Austin PC: Propensity-score matching in the cardiovascular surgery literature from 2004 to 2006: a systematic review and suggestions for improvement. J Thorac Cardiovasc Surg 2007; 134: 1128-1135
25. Lim CM, Kim SW, Park JY, Kim C, Yoon SH, Lee JK: Fluoxetine affords robust neuroprotection in the postischemic brain via its antiinflammatory effect. J Neurosci Res 2009; 87: 1037-1045
26. Ostergaard L, Jespersen SN, Mouridsen K, Mikkelsen IK, Jonsdottír KÝ, Tietze A, Blicher JU, Aamand R, Hjort N, Iversen NK, Cai C, Hougaard KD, Simonsen CZ, Von Weitzel-Mudersbach P, Modrau B, Nagenthiraja K, Riisgaard Ribe L, Hansen MB, Bekke SL, Dahlman MG, Puig J, Pedraza S, Serena J, Cho TH, Siemonsen S, Thomalla G, Fiehler J, Nighoghossian N, Andersen G: The role of the cerebral capillaries in acute ischemic stroke: the extended penumbra model. J Cereb Blood Flow Metab 2013; 33: 635-648
27. Maurer-Spurej E, Pittendreigh C, Solomons K: The influence of selective serotonin reuptake inhibitors on human platelet serotonin. Thromb Haemost 2004; 91: 119-128
28. Hackett ML, Anderson CS: Predictors of depression after stroke: a systematic review of observational studies. Stroke 2005; 36: 2296-2301
29. Mead GE, Dennis M, Lundström E, Murray V, Hackett M, Hankey GJ: Letter by Mead et al regarding article, 'selective serotonin reuptake inhibitors for stroke: more trials are needed'. Stroke 2013; 44:e40-e41
30. Kraglund KL, Mortensen JK, Grove EL, Johnsen SP, Andersen G: TALOS: a multicenter, randomized, double-blind, placebo-controlled trial to test the effects of citalopram in patients with acute stroke. Int J Stroke 2015, Epub ahead of print