ALS-associated P56S-VAPB mutation restrains 3T3-L1 preadipocyte differentiation

Biochemical and Biophysical Research Communications

Volumn 460, Issue 3, 2015, Pages 831-837

  Tokutake, Yukako ^a   Gushima, Kazunari ^a   Miyazaki, Honami ^a   Shimosato, Takeshi ^a   Yonekura, Shinichi ^a  

^a SHINSHU UNIVERSITY   (Japan)

Author keywords

Adipocyte; ALS; Differentiation; UPR; VAPB

Indexed keywords

ACTIVATING TRANSCRIPTION FACTOR 4; ATF4 PROTEIN, MOUSE; DDIT3 PROTEIN, MOUSE; GROWTH ARREST AND DNA DAMAGE INDUCIBLE PROTEIN 153; PRIMER DNA; VAPB PROTEIN, HUMAN; VESICULAR TRANSPORT PROTEIN;

3T3 CELL LINE; ADIPOCYTE; AMYOTROPHIC LATERAL SCLEROSIS; ANIMAL; CELL DIFFERENTIATION; CYTOLOGY; GENETICS; METABOLISM; MOUSE; MUTATION; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION;

3T3-L1 CELLS; ACTIVATING TRANSCRIPTION FACTOR 4; ADIPOCYTES; AMYOTROPHIC LATERAL SCLEROSIS; ANIMALS; BASE SEQUENCE; CELL DIFFERENTIATION; DNA PRIMERS; MICE; MUTATION; POLYMERASE CHAIN REACTION; TRANSCRIPTION FACTOR CHOP; VESICULAR TRANSPORT PROTEINS;

EID: 84937764166     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.03.118     Document Type: Article

References (35)

1. B.R. Brooks, M. Sanjak, D. Belden, K. Juhasz-Pocsine, and A. Waclawik Natural history of amyotorophic lateral sclerosis R.H. Brown Jr. V. Meininger, M. Swash, Amyotorophic Lateral Sclerosis 2000 Dunitz London 31 58
2. L. Dupuis, P.F. Pradat, A.C. Ludolph, and J.P. Loeffler Energy metabolism in amyotrophic lateral sclerosis Lancet Neurol. 10 2011 75 82
3. N. Vaisman, M. Lusaus, B. Nefussy, E. Niv, D. Comaneshter, R. Hallack, and V.E. Drory Do patients with amyotrophic lateral sclerosis (ALS) have increased energy needs? J. Neurol. Sci. 279 2009 26 29
4. L. Lacomblez, G. Bensimon, P.N. Leigh, P. Guillet, and V. Meininger Dose-ranging study of riluzole in amyotrophic lateral sclerosis. Amyotrophic lateral sclerosis/riluzole study group II Lancet 347 1996 1425 1431
5. J.C. Desport, P.M. Preux, T.C. Truong, J.M. Vallat, D. Sautereau, and P. Couratier Nutritional status is a prognostic factor for survival in ALS patients Neurology 53 1999 1059 1063
6. J.C. Desport, P.M. Preux, C.T. Truong, L. Courat, J.M. Vallat, and P. Couratier Nutritional assessment and survival in ALS patients Amyotroph. Lateral Scler. Other Mot. Neuron Disord. 1 2000 91 96
7. L.C. Wijesekera, and P.N. Leigh Amyotrophic lateral sclerosis Orphanet J. Rare Dis. 4 2009 3
8. E.J. Kasarskis, S. Berryman, J.G. Vanderleest, A.R. Schneider, and C.J. McClain Nutritional status of patients with amyotrophic lateral sclerosis: relation to the proximity of death Am. J. Clin. Nutr. 63 1996 130 137
9. L. Dupuis, P. Corcia, A. Fergani, J.L. Gonzalez De Aguilar, D. Bonnefont-Rousselot, R. Bittar, D. Seilhean, J.J. Hauw, L. Lacomblez, J.P. Loeffler, and V. Meininger Dyslipidemia is a protective factor in amyotrophic lateral sclerosis Neurology 70 2008 1004 1009
10. J. Dorst, P. Kuhnlein, C. Hendrich, J. Kassubek, A.D. Sperfeld, and A.C. Ludolph Patients with elevated triglyceride and cholesterol serum levels have a prolonged survival in amyotrophic lateral sclerosis J. Neurol. 258 2011 613 617
11. L.I. Bruijn, T.M. Miller, and D.W. Cleveland Unraveling the mechanisms involved in motor neuron degeneration in ALS Annu Rev. Neurosci. 27 2004 723 749
12. A.L. Nishimura, M. Mitne-Neto, H.C. Silva, A. Richieri-Costa, S. Middleton, D. Cascio, F. Kok, J.R. Oliveira, T. Gillingwater, J. Webb, P. Skehel, and M. Zatz A mutation in the vesicle-trafficking protein VAPB causes late-onset spinal muscular atrophy and amyotrophic lateral sclerosis Am. J. Hum. Genet. 75 2004 822 831
13. K. Kanekura, I. Nishimoto, S. Aiso, and M. Matsuoka Characterization of amyotrophic lateral sclerosis-linked P56S mutation of vesicle-associated membrane protein-associated protein B (VAPB/ALS8) J. Biol. Chem. 281 2006 30223 30233
14. E. Teuling, S. Ahmed, E. Haasdijk, J. Demmers, M.O. Steinmetz, A. Akhmanova, D. Jaarsma, and C.C. Hoogenraad Motor neuron disease-associated mutant vesicle-associated membrane protein-associated protein (VAP) B recruits wild-type VAPs into endoplasmic reticulum-derived tubular aggregates J. Neurosci. 27 2007 9801 9815
15. E. Fasana, M. Fossati, A. Ruggiano, S. Brambillasca, C.C. Hoogenraad, F. Navone, M. Francolini, and N. Borgese A VAPB mutant linked to amyotrophic lateral sclerosis generates a novel form of organized smooth endoplasmic reticulum FASEB J. 24 2010 1419 1430
16. C.J. Loewen, and T.P. Levine A highly conserved binding site in vesicle-associated membrane protein-associated protein (VAP) for the FFAT motif of lipid-binding proteins J. Biol. Chem. 280 2005 14097 14104
17. D.C. Prosser, D. Tran, P.Y. Gougeon, C. Verly, and J.K. Ngsee FFAT rescues VAPA-mediated inhibition of ER-to-Golgi transport and VAPB-mediated ER aggregation J. Cell. Sci. 121 2008 3052 3061
18. D. Peretti, N. Dahan, E. Shimoni, K. Hirschberg, and S. Lev Coordinated lipid transfer between the endoplasmic reticulum and the golgi complex requires the VAP proteins and is essential for golgi-mediated transport Mol. Biol. Cell. 19 2008 3871 3884
19. S. Saxena, E. Cabuy, and P. Caroni A role for motoneuron subtype-selective ER stress in disease manifestations of FALS mice Nat. Neurosci. 12 2009 627 636
20. K. Kanekura, H. Suzuki, S. Aiso, and M. Matsuoka ER stress and unfolded protein response in amyotrophic lateral sclerosis Mol. Neurobiol. 39 2009 81 89
21. 2+-dependent ER-associated pathway J. Neurochem. 114 2010 795 809
22. Z. Cao, R.M. Umek, and S.L. McKnight Regulated expression of three C/EBP isoforms during adipose conversion of 3T3-L1 cells Genes. Dev. 5 1991 1538 1552
23. P. Tontonoz, E. Hu, and B.M. Spiegelman Stimulation of adipogenesis in fibroblasts by PPAR gamma 2, a lipid-activated transcription factor Cell 79 1994 1147 1156
24. J.B. Boord, S. Fazio, and M.F. Linton Cytoplasmic fatty acid-binding proteins: emerging roles in metabolism and atherosclerosis Curr. Opin. Lipidol. 13 2002 141 147
25. B.M. Spiegelman, M. Frank, and H. Green Molecular cloning of mRNA from 3T3 adipocytes. Regulation of mRNA content for glycerophosphate dehydrogenase and other differentiation-dependent proteins during adipocyte development J. Biol. Chem. 258 1983 10083 10089
26. D.W. Waggoner, and D.A. Bernlohr In situ labeling of the adipocyte lipid binding protein with 3-[125I]iodo-4-azido-N-hexadecylsalicylamide. Evidence for a role of fatty acid binding proteins in lipid uptake J. Biol. Chem. 265 1990 11417 11420
27. H. Yoshida, T. Matsui, N. Hosokawa, R.J. Kaufman, K. Nagata, and K. Mori A time-dependent phase shift in the mammalian unfolded protein response Dev. Cell. 4 2003 265 271
28. H. Sha, Y. He, H. Chen, C. Wang, A. Zenno, H. Shi, X. Yang, X. Zhang, and L. Qi The IRE1alpha-XBP1 pathway of the unfolded protein response is required for adipogenesis Cell. Metab. 9 2009 556 564
29. Y. Ma, J.W. Brewer, J.A. Diehl, and L.M. Hendershot Two distinct stress signaling pathways converge upon the CHOP promoter during the mammalian unfolded protein response J. Mol. Biol. 318 2002 1351 1365
30. D. Ron, and J.F. Habener CHOP, a novel developmentally regulated nuclear protein that dimerizes with transcription factors C/EBP and LAP and functions as a dominant-negative inhibitor of gene transcription Genes. Dev. 6 1992 439 453
31. N. Batchvarova, X.Z. Wang, and D. Ron Inhibition of adipogenesis by the stress-induced protein CHOP (Gadd153) EMBO J. 14 1995 4654 4661
32. C. Wang, Z. Huang, Y. Du, Y. Cheng, S. Chen, and F. Guo ATF4 regulates lipid metabolism and thermogenesis Cell. Res. 20 2010 174 184
33. L. Aliaga, C. Lai, J. Yu, N. Chub, H. Shim, L. Sun, C. Xie, W.J. Yang, X. Lin, M.J. O'Donovan, and H. Cai Amyotrophic lateral sclerosis-related VAPB P56S mutation differentially affects the function and survival of corticospinal and spinal motor neurons Hum. Mol. Genet. 22 2013 4293 4305
34. A.S. Vlug, E. Teuling, E.D. Haasdijk, P. French, C.C. Hoogenraad, and D. Jaarsma ATF3 expression precedes death of spinal motoneurons in amyotrophic lateral sclerosis-SOD1 transgenic mice and correlates with c-Jun phosphorylation, CHOP expression, somato-dendritic ubiquitination and golgi fragmentation Eur. J. Neurosci. 22 2005 1881 1894
35. J.D. Atkin, M.A. Farg, A.K. Walker, C. McLean, D. Tomas, and M.K. Horne Endoplasmic reticulum stress and induction of the unfolded protein response in human sporadic amyotrophic lateral sclerosis Neurobiol. Dis. 30 2008 400 407