-
1
-
-
84890753066
-
Relevant issues in the pathology and pathobiology of pulmonary hypertension
-
R.M. Tuder, S.L. Archer, P. Dorfmuller, S.C. Erzurum, C. Guignabert, E. Michelakis, M. Rabinovitch, R. Schermuly, K.R. Stenmark, and N.W. Morrell Relevant issues in the pathology and pathobiology of pulmonary hypertension J. Am. Coll. Cardiol. 62 2013 D4 D12
-
(2013)
J. Am. Coll. Cardiol.
, vol.62
, pp. D4-D12
-
-
Tuder, R.M.1
Archer, S.L.2
Dorfmuller, P.3
Erzurum, S.C.4
Guignabert, C.5
Michelakis, E.6
Rabinovitch, M.7
Schermuly, R.8
Stenmark, K.R.9
Morrell, N.W.10
-
2
-
-
43049092988
-
An antiproliferative BMP-2/PPARgamma/apoE axis in human and murine SMCs and its role in pulmonary hypertension
-
G. Hansmann, V.A. de Jesus Perez, T.P. Alastalo, C.M. Alvira, C. Guignabert, J.M. Bekker, S. Schellong, T. Urashima, L. Wang, N.W. Morrell, and M. Rabinovitch An antiproliferative BMP-2/PPARgamma/apoE axis in human and murine SMCs and its role in pulmonary hypertension J. Clin. Invest 118 2008 1846 1857
-
(2008)
J. Clin. Invest
, vol.118
, pp. 1846-1857
-
-
Hansmann, G.1
De Jesus Perez, V.A.2
Alastalo, T.P.3
Alvira, C.M.4
Guignabert, C.5
Bekker, J.M.6
Schellong, S.7
Urashima, T.8
Wang, L.9
Morrell, N.W.10
Rabinovitch, M.11
-
4
-
-
84894491623
-
Activation of PPAR-gamma ameliorates pulmonary arterial hypertension via inducing heme oxygenase-1 and p21(WAF1): An in vivo study in rats
-
D. Zhang, G. Wang, D. Han, Y. Zhang, J. Xu, J. Lu, S. Li, X. Xie, L. Liu, L. Dong, and M. Li Activation of PPAR-gamma ameliorates pulmonary arterial hypertension via inducing heme oxygenase-1 and p21(WAF1): an in vivo study in rats Life Sci. 98 2013 39 43
-
(2013)
Life Sci.
, vol.98
, pp. 39-43
-
-
Zhang, D.1
Wang, G.2
Han, D.3
Zhang, Y.4
Xu, J.5
Lu, J.6
Li, S.7
Xie, X.8
Liu, L.9
Dong, L.10
Li, M.11
-
5
-
-
2442711384
-
Peroxisome proliferator-activated receptors and atherogenesis: Regulators of gene expression in vascular cells
-
N. Marx, H. Duez, J.C. Fruchart, and B. Staels Peroxisome proliferator-activated receptors and atherogenesis: regulators of gene expression in vascular cells Circ. Res. 94 2004 1168 1178
-
(2004)
Circ. Res.
, vol.94
, pp. 1168-1178
-
-
Marx, N.1
Duez, H.2
Fruchart, J.C.3
Staels, B.4
-
6
-
-
21544438174
-
Asymmetrical dimethylarginine in idiopathic pulmonary arterial hypertension
-
J.T. Kielstein, S.M. Bode-Boger, G. Hesse, J. Martens-Lobenhoffer, A. Takacs, D. Fliser, and M.M. Hoeper Asymmetrical dimethylarginine in idiopathic pulmonary arterial hypertension Arterioscler. Thromb. Vasc. Biol. 25 2005 1414 1418
-
(2005)
Arterioscler. Thromb. Vasc. Biol.
, vol.25
, pp. 1414-1418
-
-
Kielstein, J.T.1
Bode-Boger, S.M.2
Hesse, G.3
Martens-Lobenhoffer, J.4
Takacs, A.5
Fliser, D.6
Hoeper, M.M.7
-
7
-
-
0036890882
-
Peroxisome proliferator-activated receptor activators inhibit oxidized low-density lipoprotein-induced endothelin-1 secretion in endothelial cells
-
F. Martin-Nizard, C. Furman, P. Delerive, A. Kandoussi, J.C. Fruchart, B. Staels, and P. Duriez Peroxisome proliferator-activated receptor activators inhibit oxidized low-density lipoprotein-induced endothelin-1 secretion in endothelial cells J. Cardiovasc Pharmacol. 40 2002 822 831
-
(2002)
J. Cardiovasc Pharmacol.
, vol.40
, pp. 822-831
-
-
Martin-Nizard, F.1
Furman, C.2
Delerive, P.3
Kandoussi, A.4
Fruchart, J.C.5
Staels, B.6
Duriez, P.7
-
8
-
-
84863696819
-
Submaximal PPARgamma activation and endothelial dysfunction: New perspectives for the management of cardiovascular disorders
-
P. Balakumar, and S. Kathuria Submaximal PPARgamma activation and endothelial dysfunction: new perspectives for the management of cardiovascular disorders Br. J. Pharmacol. 166 2012 1981 1992
-
(2012)
Br. J. Pharmacol.
, vol.166
, pp. 1981-1992
-
-
Balakumar, P.1
Kathuria, S.2
-
9
-
-
1542652475
-
Nitric oxide production and regulation of endothelial nitric-oxide synthase phosphorylation by prolonged treatment with troglitazone: Evidence for involvement of peroxisome proliferator-activated receptor (PPAR) gamma-dependent and PPARgamma-independent signaling pathways
-
D.H. Cho, Y.J. Choi, S.A. Jo, and I. Jo Nitric oxide production and regulation of endothelial nitric-oxide synthase phosphorylation by prolonged treatment with troglitazone: evidence for involvement of peroxisome proliferator-activated receptor (PPAR) gamma-dependent and PPARgamma-independent signaling pathways J. Biol. Chem. 279 2004 2499 2506
-
(2004)
J. Biol. Chem.
, vol.279
, pp. 2499-2506
-
-
Cho, D.H.1
Choi, Y.J.2
Jo, S.A.3
Jo, I.4
-
10
-
-
34247368097
-
The PPAR-gamma agonist pioglitazone increases neoangiogenesis and prevents apoptosis of endothelial progenitor cells
-
C. Gensch, Y.P. Clever, C. Werner, M. Hanhoun, M. Bohm, and U. Laufs The PPAR-gamma agonist pioglitazone increases neoangiogenesis and prevents apoptosis of endothelial progenitor cells Atherosclerosis 192 2007 67 74
-
(2007)
Atherosclerosis
, vol.192
, pp. 67-74
-
-
Gensch, C.1
Clever, Y.P.2
Werner, C.3
Hanhoun, M.4
Bohm, M.5
Laufs, U.6
-
11
-
-
0009621605
-
Dynamic activation of endothelial nitric oxide synthase by Hsp90
-
G. Garcia-Cardena, R. Fan, V. Shah, R. Sorrentino, G. Cirino, A. Papapetropoulos, and W.C. Sessa Dynamic activation of endothelial nitric oxide synthase by Hsp90 Nature 392 1998 821 824
-
(1998)
Nature
, vol.392
, pp. 821-824
-
-
Garcia-Cardena, G.1
Fan, R.2
Shah, V.3
Sorrentino, R.4
Cirino, G.5
Papapetropoulos, A.6
Sessa, W.C.7
-
12
-
-
58249088751
-
MicroRNAs: Target recognition and regulatory functions
-
D.P. Bartel MicroRNAs: target recognition and regulatory functions Cell 136 2009 215 233
-
(2009)
Cell
, vol.136
, pp. 215-233
-
-
Bartel, D.P.1
-
13
-
-
77950878463
-
Dynamic changes in lung microRNA profiles during the development of pulmonary hypertension due to chronic hypoxia and monocrotaline
-
P. Caruso, M.R. MacLean, R. Khanin, J. McClure, E. Soon, M. Southgate, R.A. MacDonald, J.A. Greig, K.E. Robertson, R. Masson, L. Denby, Y. Dempsie, L. Long, N.W. Morrell, and A.H. Baker Dynamic changes in lung microRNA profiles during the development of pulmonary hypertension due to chronic hypoxia and monocrotaline Arterioscler. Thromb. Vasc. Biol. 30 2010 716 723
-
(2010)
Arterioscler. Thromb. Vasc. Biol.
, vol.30
, pp. 716-723
-
-
Caruso, P.1
Maclean, M.R.2
Khanin, R.3
McClure, J.4
Soon, E.5
Southgate, M.6
Macdonald, R.A.7
Greig, J.A.8
Robertson, K.E.9
Masson, R.10
Denby, L.11
Dempsie, Y.12
Long, L.13
Morrell, N.W.14
Baker, A.H.15
-
14
-
-
84858629938
-
MiR-27b controls venous specification and tip cell fate
-
D. Biyashev, D. Veliceasa, J. Topczewski, J.M. Topczewska, I. Mizgirev, E. Vinokour, A.L. Reddi, J.D. Licht, S.Y. Revskoy, and O.V. Volpert miR-27b controls venous specification and tip cell fate Blood 119 2012 2679 2687
-
(2012)
Blood
, vol.119
, pp. 2679-2687
-
-
Biyashev, D.1
Veliceasa, D.2
Topczewski, J.3
Topczewska, J.M.4
Mizgirev, I.5
Vinokour, E.6
Reddi, A.L.7
Licht, J.D.8
Revskoy, S.Y.9
Volpert, O.V.10
-
15
-
-
84856812740
-
MicroRNA-27a/b controls endothelial cell repulsion and angiogenesis by targeting semaphorin 6A
-
C. Urbich, D. Kaluza, T. Fromel, A. Knau, K. Bennewitz, R.A. Boon, A. Bonauer, C. Doebele, J.N. Boeckel, E. Hergenreider, A.M. Zeiher, J. Kroll, I. Fleming, and S. Dimmeler MicroRNA-27a/b controls endothelial cell repulsion and angiogenesis by targeting semaphorin 6A Blood 119 2012 1607 1616
-
(2012)
Blood
, vol.119
, pp. 1607-1616
-
-
Urbich, C.1
Kaluza, D.2
Fromel, T.3
Knau, A.4
Bennewitz, K.5
Boon, R.A.6
Bonauer, A.7
Doebele, C.8
Boeckel, J.N.9
Hergenreider, E.10
Zeiher, A.M.11
Kroll, J.12
Fleming, I.13
Dimmeler, S.14
-
16
-
-
84877766516
-
Prooncogenic factors miR-23b and miR-27b are regulated by Her2/Neu, EGF, and TNF-alpha in breast cancer
-
L. Jin, O. Wessely, E.G. Marcusson, C. Ivan, G.A. Calin, and S.K. Alahari Prooncogenic factors miR-23b and miR-27b are regulated by Her2/Neu, EGF, and TNF-alpha in breast cancer Cancer Res. 73 2013 2884 2896
-
(2013)
Cancer Res.
, vol.73
, pp. 2884-2896
-
-
Jin, L.1
Wessely, O.2
Marcusson, E.G.3
Ivan, C.4
Calin, G.A.5
Alahari, S.K.6
-
17
-
-
84876074187
-
MiRNA-27b targets vascular endothelial growth factor C to inhibit tumor progression and angiogenesis in colorectal cancer
-
J. Ye, X. Wu, D. Wu, P. Wu, C. Ni, Z. Zhang, Z. Chen, F. Qiu, J. Xu, and J. Huang miRNA-27b targets vascular endothelial growth factor C to inhibit tumor progression and angiogenesis in colorectal cancer PLoS One 8 2013 e60687
-
(2013)
PLoS One
, vol.8
, pp. e60687
-
-
Ye, J.1
Wu, X.2
Wu, D.3
Wu, P.4
Ni, C.5
Zhang, Z.6
Chen, Z.7
Qiu, F.8
Xu, J.9
Huang, J.10
-
18
-
-
70350125874
-
MicroRNA miR-27b impairs human adipocyte differentiation and targets PPARgamma
-
M. Karbiener, C. Fischer, S. Nowitsch, P. Opriessnig, C. Papak, G. Ailhaud, C. Dani, E.Z. Amri, and M. Scheideler microRNA miR-27b impairs human adipocyte differentiation and targets PPARgamma Biochem. Biophys. Res. Commun. 390 2009 247 251
-
(2009)
Biochem. Biophys. Res. Commun.
, vol.390
, pp. 247-251
-
-
Karbiener, M.1
Fischer, C.2
Nowitsch, S.3
Opriessnig, P.4
Papak, C.5
Ailhaud, G.6
Dani, C.7
Amri, E.Z.8
Scheideler, M.9
-
19
-
-
84865226215
-
MiR-27b targets PPARgamma to inhibit growth, tumor progression and the inflammatory response in neuroblastoma cells
-
J.J. Lee, A. Drakaki, D. Iliopoulos, and K. Struhl MiR-27b targets PPARgamma to inhibit growth, tumor progression and the inflammatory response in neuroblastoma cells Oncogene 31 2012 3818 3825
-
(2012)
Oncogene
, vol.31
, pp. 3818-3825
-
-
Lee, J.J.1
Drakaki, A.2
Iliopoulos, D.3
Struhl, K.4
-
20
-
-
84919597213
-
MiR-203 inhibits melanoma invasive and proliferative abilities by targeting the polycomb group gene BMI1
-
X. Chang, Y. Sun, S. Han, W. Zhu, H. Zhang, and S. Lian MiR-203 inhibits melanoma invasive and proliferative abilities by targeting the polycomb group gene BMI1 Biochem. Biophys. Res. Commun. 456 2015 361 366
-
(2015)
Biochem. Biophys. Res. Commun.
, vol.456
, pp. 361-366
-
-
Chang, X.1
Sun, Y.2
Han, S.3
Zhu, W.4
Zhang, H.5
Lian, S.6
-
21
-
-
0035020086
-
Nitric oxide attenuates H(2)O(2)-induced endothelial barrier dysfunction: Mechanisms of protection
-
M.P. Gupta, M.D. Ober, C. Patterson, M. Al-Hassani, V. Natarajan, and C.M. Hart Nitric oxide attenuates H(2)O(2)-induced endothelial barrier dysfunction: mechanisms of protection Am. J. Physiol. Lung Cell. Mol. Physiol. 280 2001 L116 L126
-
(2001)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.280
, pp. L116-L126
-
-
Gupta, M.P.1
Ober, M.D.2
Patterson, C.3
Al-Hassani, M.4
Natarajan, V.5
Hart, C.M.6
-
22
-
-
33845565499
-
Cardioprotection mediated by rosiglitazone, a peroxisome proliferator-activated receptor gamma ligand, in relation to nitric oxide
-
A.T. Gonon, A. Bulhak, F. Labruto, P.O. Sjoquist, and J. Pernow Cardioprotection mediated by rosiglitazone, a peroxisome proliferator-activated receptor gamma ligand, in relation to nitric oxide Basic Res. Cardiol. 102 2007 80 89
-
(2007)
Basic Res. Cardiol.
, vol.102
, pp. 80-89
-
-
Gonon, A.T.1
Bulhak, A.2
Labruto, F.3
Sjoquist, P.O.4
Pernow, J.5
-
23
-
-
42549153011
-
Cardioprotective mechanism of telmisartan via PPAR-gamma-eNOS pathway in dahl salt-sensitive hypertensive rats
-
N. Kobayashi, T. Ohno, K. Yoshida, H. Fukushima, Y. Mamada, M. Nomura, H. Hirata, Y. Machida, M. Shinoda, N. Suzuki, and H. Matsuoka Cardioprotective mechanism of telmisartan via PPAR-gamma-eNOS pathway in dahl salt-sensitive hypertensive rats Am. J. Hypertens. 21 2008 576 581
-
(2008)
Am. J. Hypertens.
, vol.21
, pp. 576-581
-
-
Kobayashi, N.1
Ohno, T.2
Yoshida, K.3
Fukushima, H.4
Mamada, Y.5
Nomura, M.6
Hirata, H.7
Machida, Y.8
Shinoda, M.9
Suzuki, N.10
Matsuoka, H.11
-
24
-
-
66949118228
-
Interleukin-6 modulates the expression of the bone morphogenic protein receptor type II through a novel STAT3-microRNA cluster 17/92 pathway
-
M. Brock, M. Trenkmann, R.E. Gay, B.A. Michel, S. Gay, M. Fischler, S. Ulrich, R. Speich, and L.C. Huber Interleukin-6 modulates the expression of the bone morphogenic protein receptor type II through a novel STAT3-microRNA cluster 17/92 pathway Circ. Res. 104 2009 1184 1191
-
(2009)
Circ. Res.
, vol.104
, pp. 1184-1191
-
-
Brock, M.1
Trenkmann, M.2
Gay, R.E.3
Michel, B.A.4
Gay, S.5
Fischler, M.6
Ulrich, S.7
Speich, R.8
Huber, L.C.9
-
25
-
-
84857791711
-
Cardiomyocyte overexpression of miR-27b induces cardiac hypertrophy and dysfunction in mice
-
J. Wang, Y. Song, Y. Zhang, H. Xiao, Q. Sun, N. Hou, S. Guo, Y. Wang, K. Fan, D. Zhan, L. Zha, Y. Cao, Z. Li, X. Cheng, and X. Yang Cardiomyocyte overexpression of miR-27b induces cardiac hypertrophy and dysfunction in mice Cell. Res. 22 2012 516 527
-
(2012)
Cell. Res.
, vol.22
, pp. 516-527
-
-
Wang, J.1
Song, Y.2
Zhang, Y.3
Xiao, H.4
Sun, Q.5
Hou, N.6
Guo, S.7
Wang, Y.8
Fan, K.9
Zhan, D.10
Zha, L.11
Cao, Y.12
Li, Z.13
Cheng, X.14
Yang, X.15
-
26
-
-
77951219696
-
MicroRNA-27b contributes to lipopolysaccharide-mediated peroxisome proliferator-activated receptor gamma (PPARgamma) mRNA destabilization
-
C. Jennewein, A. von Knethen, T. Schmid, and B. Brune MicroRNA-27b contributes to lipopolysaccharide-mediated peroxisome proliferator-activated receptor gamma (PPARgamma) mRNA destabilization J. Biol. Chem. 285 2010 11846 11853
-
(2010)
J. Biol. Chem.
, vol.285
, pp. 11846-11853
-
-
Jennewein, C.1
Von Knethen, A.2
Schmid, T.3
Brune, B.4
-
27
-
-
84866049101
-
PPAR-gamma regulates carnitine homeostasis and mitochondrial function in a lamb model of increased pulmonary blood flow
-
S. Sharma, X. Sun, R. Rafikov, S. Kumar, Y. Hou, P.E. Oishi, S.A. Datar, G. Raff, J.R. Fineman, and S.M. Black PPAR-gamma regulates carnitine homeostasis and mitochondrial function in a lamb model of increased pulmonary blood flow PLoS One 7 2012 e41555
-
(2012)
PLoS One
, vol.7
, pp. e41555
-
-
Sharma, S.1
Sun, X.2
Rafikov, R.3
Kumar, S.4
Hou, Y.5
Oishi, P.E.6
Datar, S.A.7
Raff, G.8
Fineman, J.R.9
Black, S.M.10
-
28
-
-
0038389113
-
Peroxisome proliferator-activated receptor gamma (PPARgamma) expression is decreased in pulmonary hypertension and affects endothelial cell growth
-
S. Ameshima, H. Golpon, C.D. Cool, D. Chan, R.W. Vandivier, S.J. Gardai, M. Wick, R.A. Nemenoff, M.W. Geraci, and N.F. Voelkel Peroxisome proliferator-activated receptor gamma (PPARgamma) expression is decreased in pulmonary hypertension and affects endothelial cell growth Circ. Res. 92 2003 1162 1169
-
(2003)
Circ. Res.
, vol.92
, pp. 1162-1169
-
-
Ameshima, S.1
Golpon, H.2
Cool, C.D.3
Chan, D.4
Vandivier, R.W.5
Gardai, S.J.6
Wick, M.7
Nemenoff, R.A.8
Geraci, M.W.9
Voelkel, N.F.10
-
29
-
-
34447571984
-
The role of peroxisome proliferator-activated receptors in pulmonary vascular disease
-
R.E. Nisbet, R.L. Sutliff, and C.M. Hart The role of peroxisome proliferator-activated receptors in pulmonary vascular disease PPAR Res. 2007 2007 18797
-
(2007)
PPAR Res.
, vol.2007
, pp. 18797
-
-
Nisbet, R.E.1
Sutliff, R.L.2
Hart, C.M.3
-
30
-
-
77950485024
-
Rosiglitazone attenuates chronic hypoxia-induced pulmonary hypertension in a mouse model
-
R.E. Nisbet, J.M. Bland, D.J. Kleinhenz, P.O. Mitchell, E.R. Walp, R.L. Sutliff, and C.M. Hart Rosiglitazone attenuates chronic hypoxia-induced pulmonary hypertension in a mouse model Am. J. Respir. Cell. Mol. Biol. 42 2010 482 490
-
(2010)
Am. J. Respir. Cell. Mol. Biol.
, vol.42
, pp. 482-490
-
-
Nisbet, R.E.1
Bland, J.M.2
Kleinhenz, D.J.3
Mitchell, P.O.4
Walp, E.R.5
Sutliff, R.L.6
Hart, C.M.7
-
31
-
-
77951222644
-
PPARgamma and the pathobiology of pulmonary arterial hypertension
-
M. Rabinovitch PPARgamma and the pathobiology of pulmonary arterial hypertension Adv. Exp. Med. Biol. 661 2010 447 458
-
(2010)
Adv. Exp. Med. Biol.
, vol.661
, pp. 447-458
-
-
Rabinovitch, M.1
-
32
-
-
0037231474
-
Peroxisome proliferator-activated receptor gamma ligands increase release of nitric oxide from endothelial cells
-
D.S. Calnek, L. Mazzella, S. Roser, J. Roman, and C.M. Hart Peroxisome proliferator-activated receptor gamma ligands increase release of nitric oxide from endothelial cells Arterioscler. Thromb. Vasc. Biol. 23 2003 52 57
-
(2003)
Arterioscler. Thromb. Vasc. Biol.
, vol.23
, pp. 52-57
-
-
Calnek, D.S.1
Mazzella, L.2
Roser, S.3
Roman, J.4
Hart, C.M.5
-
33
-
-
24144448954
-
Peroxisome proliferator-activated receptor gamma ligands stimulate endothelial nitric oxide production through distinct peroxisome proliferator-activated receptor gamma-dependent mechanisms
-
J.A. Polikandriotis, L.J. Mazzella, H.L. Rupnow, and C.M. Hart Peroxisome proliferator-activated receptor gamma ligands stimulate endothelial nitric oxide production through distinct peroxisome proliferator-activated receptor gamma-dependent mechanisms Arterioscler. Thromb. Vasc. Biol. 25 2005 1810 1816
-
(2005)
Arterioscler. Thromb. Vasc. Biol.
, vol.25
, pp. 1810-1816
-
-
Polikandriotis, J.A.1
Mazzella, L.J.2
Rupnow, H.L.3
Hart, C.M.4
-
34
-
-
37149044207
-
Nitric oxide and superoxide generation from endothelial NOS: Modulation by HSP90
-
N. Sud, S. Sharma, D.A. Wiseman, C. Harmon, S. Kumar, R.C. Venema, J.R. Fineman, and S.M. Black Nitric oxide and superoxide generation from endothelial NOS: modulation by HSP90 Am. J. Physiol. Lung Cell. Mol. Physiol. 293 2007 L1444 L1453
-
(2007)
Am. J. Physiol. Lung Cell. Mol. Physiol.
, vol.293
, pp. L1444-L1453
-
-
Sud, N.1
Sharma, S.2
Wiseman, D.A.3
Harmon, C.4
Kumar, S.5
Venema, R.C.6
Fineman, J.R.7
Black, S.M.8
|