Reversal of warfarin anticoagulation for urgent surgical procedures;La neutralisation de l’anticoagulation induite par la warfarine lors d’interventions chirurgicales urgentes

Canadian Journal of Anesthesia

Volumn 62, Issue 6, 2015, Pages 634-649

  Curtis, Rachel ^a   Schweitzer, Alexandra ^a   van Vlymen, Janet ^a  

^a QUEEN S UNIVERSITY   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

ANTICOAGULANT AGENT; BLOOD CLOTTING FACTOR; PHYTOMENADIONE; PROTHROMBIN COMPLEX CONCENTRATES; WARFARIN;

BLOOD LOSS, SURGICAL; HEMORRHAGE; HUMAN; PREOPERATIVE CARE; PROCEDURES; TIME FACTOR;

ANTICOAGULANTS; BLOOD COAGULATION FACTORS; BLOOD LOSS, SURGICAL; HEMORRHAGE; HUMANS; PREOPERATIVE CARE; TIME FACTORS; VITAMIN K 1; WARFARIN;

EID: 84937761515     PISSN: 0832610X     EISSN: 14968975     Source Type: Journal    
DOI: 10.1007/s12630-015-0366-3     Document Type: Article

References (34)

1. Xu Y, Holbrook AM, Simpson CS, Dowlatshahi D, Johnson AP. Prescribing patterns of novel oral anticoagulants following regulatory approval for atrial fibrillation in Ontario, Canada: a population-based descriptive analysis. CMAJ Open 2013; 1: E115-9.
2. th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest 2012; 141(2 Suppl): e44S-88S.
3. Hirsh J, Dalen JE, Anderson DR, et al. Oral anticoagulants: mechanism of action, clinical effectiveness, and optimal therapeutic range. Chest 2001; 119(1 Suppl): 8S-21S.
4. th Edition). Chest 2008; 133(6 Suppl): 160S-98S.
5. th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest 2012; 141(2 Suppl): e326S-50S.
6. Spyropoulos AC, Douketis JD. How I treat anticoagulated patients undergoing an elective procedure or surgery. Blood 2012; 120: 2954-62.
7. Canadian Society for Transfusion Medicine. Five Things Physicians and Patients Should Question. Available from URL: http://www.choosingwiselycanada.org/recommendations/transfusion-medicine/ (accessed February 2015).
8. Horlocker TT, Wedel DJ, Rowlingson JC, et al. Regional anesthesia in the patient receiving antithrombotic or thrombolytic therapy: American Society of Regional Anesthesia and Pain Medicine Evidence-Based Guidelines (Third Edition). Reg Anesth Pain Med 2010; 35: 64-101.
9. National Advisory Committee on Blood and Blood Products. Recommendations for the use of Prothrombin Complex Concentrates in Canada. Available from URL: http://www.nacblood.ca/resources/guidelines/PCC-Recommendations-Final-2014-05-16.pdf (accessed February 2015).
10. Tran HA, Chunilal SD, Harper PL, et al. An update of consensus guidelines for warfarin reversal. Med J Aust 2013; 198: 198-9.
11. Dentali F, Ageno W, Crowther M. Treatment of coumarin-associated coagulopathy: a systematic review and proposed treatment algorithms. J Thromb Haemost 2006; 4: 1853-63.
12. Watson HG, Baglin T, Laidlaw SL, Makris M, Preston FE. A comparison of the efficacy and rate of response to oral and intravenous vitamin K in reversal of over-anticoagulation with warfarin. Br J Haematol 2001; 115: 145-9.
13. Keeling D, Baglin T, Tait C, et al.; British Committee for Standards in Haematology. Guidelines on oral anticoagulation with warfarin – fourth edition. Br J Haematol 2011; 154: 311-24.
14. th ed: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest 2012; 141(2 Suppl): e152S-84S.
15. Fiore LD, Scola MA, Cantillon CE, Brophy MT. Anaphylactoid reactions to vitamin K. J Thromb Thrombolysis 2001; 11: 175-83.
16. Rodgers GM. Prothrombin complex concentrates in emergency bleeding disorders. Am J Hematol 2012; 87: 898-902.
17. ® Product Monograph. Available from URL: http://www.octapharma.ca/fileadmin/user_upload/octapharma.ca/20120613_PM_Octaplex_approved.pdf (accessed February 2015).
18. ® Product Monograph. Available from URL: http://www.cslbehring.ca/canadian-products-monographs (accessed February 2015).
19. ® in Canada. Available from URL: http://www.nacblood.ca/resources/guidelines/downloads/recommendations-for-use-of-octaplex.pdf (accessed February 2015).
20. Van Aart L, Eijkhout HW, Kamphuis JS, et al. Individualized dosing regimen for prothrombin complex concentrate more effective than standard treatment in the reversal of oral anticoagulant therapy: an open, prospective randomized controlled trial. Thromb Res 2006; 118: 313-20.
21. Hanke AA, Joch C, Gorlinger K. Long-term safety and efficacy of a pasteurized nanofiltrated prothrombin complex concentrate (Beriplex P/N): a pharmacovigilance study. Br J Anaesth 2013; 110: 764-72.
22. Dentali F, Marchesi C, Pierfranceschi MG, et al. Safety of prothrombin complex concentrates for rapid anticoagulation reversal of vitamin K antagonists. A meta-analysis. Thromb Haemost 2011; 106: 429-38.
23. Franchini M, Lippi G. Prothrombin complex concentrates: an update. Blood Transfus 2010; 8: 149-54.
24. Sarode R, Milling TJ Jr, Refaai MA, et al. Efficacy and safety of a 4-factor prothrombin complex concentrate in patients on vitamin K antagonists presenting with major bleeding: a randomized, plasma-controlled, phase IIIb study. Circulation 2013; 128: 1234-43.
25. Hickey M, Gatien M, Taljaard M, Aujnarain A, Giulivi A, Perry JJ. Outcomes of urgent warfarin reversal using fresh frozen plasma versus prothrombin complex concentrate in the emergency department. Circulation 2013; 128: 360-4.
26. Canadian Blood Services. Clinical Guide to Transfusion Medicine. Available from URL: http://www.transfusionmedicine.ca/sites/transfusionmedicine/files/articles/CGTTChapter2_MAR2013_FINAL.pdf (accessed February 2015).
27. O’Shaughnessy DF, Atterbury C, Bolton Maggs P, et al.; British Committee for Standards in Haematology Blood Transfusion Task Force. Guidelines for the use of fresh-frozen plasma, cryoprecipitate and cryosupernatant. Br J Haematol 2004; 126: 11-28.
28. Holland LL, Brooks JP. Toward rational fresh frozen plasma transfusion: the effect of plasma transfusion on coagulation test results. Am J Clin Pathol 2006; 126: 133-9.
29. Abdel-Wahab OI, Healy B, Dzik WH. Effect of fresh-frozen plasma transfusion on prothrombin time and bleeding in patients with mild coagulation abnormalities. Transfusion 2006; 46: 1279-85.
30. Narick C, Triulzi DJ, Yazer MH. Transfusion-associated circulatory overload after plasma transfusion. Transfusion 2012; 52: 160-5.
31. Tinmouth A, Thompson T, Arnold DM, et al. Utilization of frozen plasma in Ontario: a provincewide audit reveals a high rate of inappropriate transfusions. Transfusion 2013; 53: 2222-9.
32. Lin Y,Callum J. Emergency reversal of warfarin anticoagulation. CMAJ 2010; 182: 2004.
33. Guyatt GH, Akl EA, Crowther M, Gutterman DD, Schuunemann HJ; American College of Chest Physicians Antithrombotic Therapy and Prevention of Thrombosis Panel. Executive summary: Antithrombotic Therapy and Prevention of Thrombosis: American College of Chest Physicians Evidence-Based Clinical Practice Guidelines. Chest 2012; 141(2 Suppl): 7S-47S.
34. rd ed. Canada: Ontario Regional Blood Coordination Network; 2011: 136. Available from URL: http://www.transfusionmedicine.ca/resources/links/textbooks-handbooks/bloody-easy-2-blood-transfusions-blood-alternatives-and-transfus (accessed February 2015).