Active site labeling of cysteine cathepsins by a straightforward diazomethylketone probe derived from the N-terminus of human cystatin C

Biochemical and Biophysical Research Communications

Volumn 460, Issue 2, 2015, Pages 250-254

  Garenne, Thibaut ^a   Saidi, Ahlame ^a   Gilmore, Brendan F ^b   Niemiec, Elzbieta ^c   Roy, Vincent ^c   Agrofoglio, Luigi A ^c   Kasabova, Mariana ^a,d   Lecaille, Fabien ^a   Lalmanach, Gilles ^a  

^a Université de Tours Centre d'Étude des Pathologies Respiratoires Inserm U1100   (France)

^b QUEEN'S UNIVERSITY BELFAST   (United Kingdom)

^c UNIVERSITÉ D'ORLÉANS   (France)

^d UNIVERSITY OF LIÈGE   (Belgium)

Author keywords

Activity based probe; Affinity labeling; Cathepsin; Cystatin; Cysteine protease

Indexed keywords

AFFINITY LABELING; CATHEPSIN; CYSTATIN C; DIAZOMETHANE; DIAZOMETHYL KETONES; MOLECULAR PROBE;

AFFINITY LABELING; ANALOGS AND DERIVATIVES; CELL LINE; CHEMISTRY; ENZYME ACTIVE SITE; HUMAN; MOLECULAR PROBE;

AFFINITY LABELS; CATALYTIC DOMAIN; CATHEPSINS; CELL LINE; CYSTATIN C; DIAZOMETHANE; HUMANS; MOLECULAR PROBES;

EID: 84937758444     PISSN: 0006291X     EISSN: 10902104     Source Type: Journal    
DOI: 10.1016/j.bbrc.2015.03.020     Document Type: Article

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