Two novel frameshift mutations in BRCA2 gene detected by next generation sequencing in a survey of Spanish patients of breast cancer

Clinical and Translational Oncology

Volumn 17, Issue 7, 2015, Pages 576-580

  Hernan, I ^a   Mane B ^a   Borras E ^a   de Sousa Dias, M ^a   Llort, G ^b   Yague C ^b   Gamundi, M J ^a   Arcusa, A ^a   Carballo, M ^a  

^a HOSPITAL DE TERRASSA   (Spain)

^b Brain   (Spain)

Author keywords

BRCA1 and BRCA2; Hereditary breast cancer; Molecular genetic testing; Next generation sequencing

Indexed keywords

GENOMIC DNA;

ADULT; ARTICLE; BRCA2 GENE; BREAST CANCER; CANCER PATIENT; DNA SEQUENCE; EXON; FRAMESHIFT MUTATION; GENE DELETION; GENE INSERTION; GENETIC SCREENING; GERMLINE MUTATION; HUMAN; MAJOR CLINICAL STUDY; MULTIPLEX POLYMERASE CHAIN REACTION; MUTATIONAL ANALYSIS; NEXT GENERATION SEQUENCING; ONCOGENE; OVARY CANCER; SPAIN; TUMOR SUPPRESSOR GENE; AGED; BREAST TUMOR; CAUCASIAN; FEMALE; GENETICS; HEREDITARY BREAST AND OVARIAN CANCER SYNDROME; HIGH THROUGHPUT SEQUENCING; MIDDLE AGED;

ADULT; AGED; BREAST NEOPLASMS; EUROPEAN CONTINENTAL ANCESTRY GROUP; FEMALE; FRAMESHIFT MUTATION; GENES, BRCA1; GENES, BRCA2; GERM-LINE MUTATION; HEREDITARY BREAST AND OVARIAN CANCER SYNDROME; HIGH-THROUGHPUT NUCLEOTIDE SEQUENCING; HUMANS; MIDDLE AGED; SPAIN;

EID: 84937641141     PISSN: 1699048X     EISSN: 16993055     Source Type: Journal    
DOI: 10.1007/s12094-014-1271-x     Document Type: Article

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