Systemic exposure to a common periodontal pathogen and missing teeth are associated with metabolic syndrome

Acta Diabetologica

Volumn 52, Issue 1, 2015, Pages 179-182

  Hyvarinen K ^a   Salminen, A ^a   Salomaa, V ^b   Pussinen, P J ^a  

^a UNIVERSITY OF HELSINKI   (Finland)

^b NATIONAL PUBLIC HEALTH INSTITUTE   (Finland)

Author keywords

Dyslipidemia; Insulin resistance; Oral infection; Periodontitis

Indexed keywords

BACTERIUM ANTIBODY;

AGED; AGGREGATIBACTER ACTINOMYCETEMCOMITANS; BLOOD; CHEMISTRY; COHORT ANALYSIS; COMPLICATION; FEMALE; FINLAND; HUMAN; IMMUNOLOGY; ISOLATION AND PURIFICATION; MALE; METABOLIC SYNDROME X; MICROBIOLOGY; MIDDLE AGED; PERIODONTAL DISEASE; PERIODONTITIS; PORPHYROMONAS GINGIVALIS; TOOTH;

AGED; AGGREGATIBACTER ACTINOMYCETEMCOMITANS; ANTIBODIES, BACTERIAL; COHORT STUDIES; FEMALE; FINLAND; HUMANS; MALE; METABOLIC SYNDROME X; MIDDLE AGED; PERIODONTITIS; PORPHYROMONAS GINGIVALIS; TOOTH; TOOTH LOSS;

EID: 84937632997     PISSN: 09405429     EISSN: 14325233     Source Type: Journal    
DOI: 10.1007/s00592-014-0586-y     Document Type: Article

References (6)

1. Lockhart PB, Bolger AF, Papapanou PN, Osinbowale O, Trevisan M, Levison ME, Taubert KA, Newburger JW, Gornik HL, Gewitz MH, Wilson WR, Smith SC,Jr, Baddour LM, American Heart Association Rheumatic Fever, Endocarditis, and Kawasaki Disease Committee of the Council on Cardiovascular Disease in the Young, Council on Epidemiology and Prevention, Council on Peripheral Vascular Disease, and Council on Clinical Cardiology (2012) Periodontal disease and atherosclerotic vascular disease: does the evidence support an independent association?: a scientific statement from the American Heart Association. Circulation 125:2520–2544
2. Nibali L, Tatarakis N, Needleman I, Tu Y, D’Aiuto F, Rizzo M, Donos N (2013) Association between metabolic syndrome and periodontitis: a systematic review and meta-analysis. J Clin Endocrinol Metab 98:913–920
3. Pussinen PJ, Jousilahti P, Alfthan G, Palosuo T, Asikainen S, Salomaa V (2003) Antibodies to periodontal pathogens are associated with coronary heart disease. Arterioscler Thromb Vasc Biol 23:1250–1254
4. Alberti KGMM, Eckel RH, Grundy SM, Zimmet PZ, Cleeman JI, Donato KA, Fruchart J, James WPT, Loria CM, Smith SC (2009) Harmonizing the metabolic syndrome: a joint interim statement of the International Diabetes Federation Task Force on Epidemiology and Prevention; National Heart, Lung, and Blood Institute; American Heart Association; World Heart Federation; International Atherosclerosis Society; and International Association for the Study of Obesity. Circulation 120:1640–1645
5. Pussinen PJ, Havulinna AS, Lehto M, Sundvall J, Salomaa V (2011) Endotoxemia is associated with an increased risk of incident diabetes. Diabetes Care 34:392–397
6. Hyvärinen K (2013) Proatherogenic effects of common pathogens on liver, adipose tissue and coronary artery disease. Doctoral dissertation. Institute of Dentistry, Faculty of Medicine, University of Helsinki. http://urn.fi/URN:ISBN:978-952-10-8789-9