Survival and persistence of Bacillus clausii in the human gastrointestinal tract following oral administration as spore-based probiotic formulation

Journal of Applied Microbiology

Volumn 119, Issue 2, 2015, Pages 552-559

  Ghelardi, Emilia ^a   Celandroni, F ^a   Salvetti, S ^a,b   Gueye, S A ^a   Lupetti, A ^a   Senesi, S ^a  

^a UNIVERSITY OF PISA   (Italy)

^b SAN GIUSEPPE HOSPITAL   (Italy)

Author keywords

Bacillus; Bacterial spores; Gut; Human study; Oral administration

Indexed keywords

BACILLI; BIOTECHNOLOGY; GERMINATION;

BACILLUS CLAUSII; BACTERIAL SPORE; CROSS-OVER; GASTROINTESTINAL TRACT; GUT; HEALTHY VOLUNTEERS; HUMAN STUDY; LIQUID FORMULATIONS; ORAL ADMINISTRATION; PROBIOTICS;

BACTERIOLOGY;

PROBIOTIC AGENT;

ANTIBIOTIC RESISTANCE; BACTERIUM; BIOTECHNOLOGY; DOSE-RESPONSE RELATIONSHIP; FECES; HOMINID; IDENTIFICATION METHOD; ORAL HEALTH; PERSISTENCE; PROBIOTICS; SPORE; SURVIVAL;

ADULT; ANTIBIOTIC RESISTANCE; ARTICLE; BACILLUS; BACILLUS CLAUSII; BACTERIAL SPORE; BACTERIAL STRAIN; BACTERIAL SURVIVAL; BACTERIUM IDENTIFICATION; BIOEQUIVALENCE; CONTROLLED STUDY; CROSSOVER PROCEDURE; DRUG FECES LEVEL; FECES ANALYSIS; FEMALE; GASTROINTESTINAL TRACT; GERMINATION; HUMAN; MALE; NORMAL HUMAN; OPEN STUDY; POLYMERASE CHAIN REACTION; RANDOM AMPLIFIED POLYMORPHIC DNA; RANDOMIZED CONTROLLED TRIAL; SINGLE DRUG DOSE; FECES; GENETICS; GROWTH, DEVELOPMENT AND AGING; MICROBIOLOGY; ORAL DRUG ADMINISTRATION;

BACILLUS (BACTERIUM); BACILLUS CLAUSII; BACTERIA (MICROORGANISMS);

ADMINISTRATION, ORAL; ADULT; BACILLUS; FECES; FEMALE; GASTROINTESTINAL TRACT; HUMANS; MALE; PROBIOTICS; RANDOM AMPLIFIED POLYMORPHIC DNA TECHNIQUE; SPORES, BACTERIAL;

EID: 84937631424     PISSN: 13645072     EISSN: 13652672     Source Type: Journal    
DOI: 10.1111/jam.12848     Document Type: Article

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