Natural history of chronic HBV infection in West Africa: A longitudinal population-based study from The Gambia

Gut

Volumn 65, Issue 12, 2016, Pages 2007-2016

  Shimakawa, Yusuke ^a,b,c   Lemoine, Maud ^a,d   Njai, Harr Freeya ^a   Bottomley, Christian ^b   Ndow, Gibril ^a   Goldin, Robert D ^d   Jatta, Abdoulie ^a   Jeng Barry, Adam ^a   Wegmuller, Rita ^a   Moore, Sophie E ^a,b   Baldeh, Ignatius ^e   Taal, Makie ^e   D'Alessandro, Umberto ^a,b   Whittle, Hilton ^b   Njie, Ramou ^a   Thursz, Mark ^d   Mendy, Maimuna ^f  

^a MEDICAL RESEARCH COUNCIL LABORATORIES   (Gambia)

^b LONDON SCHOOL OF HYGIENE AND TROPICAL MEDICINE   (United Kingdom)

^c INSTITUT PASTEUR   (France)

^d IMPERIAL COLLEGE LONDON   (United Kingdom)

^e MINISTRY OF HEALTH AND SOCIAL WELFARE   (Gambia)

^f INTERNATIONAL AGENCY FOR RESEARCH ON CANCER   (France)

Author keywords

EPIDEMIOLOGY; HEPATITIS B; HEPATOCELLULAR CARCINOMA

Indexed keywords

AFLATOXIN B1; HEPATITIS B SURFACE ANTIGEN; HEPATITIS B(E) ANTIGEN; BIOLOGICAL MARKER;

ADOLESCENT; ADULT; ANTIVIRAL THERAPY; ARTICLE; CANCER INCIDENCE; CHILD; CHRONIC HEPATITIS B; CONTROLLED STUDY; DISEASE ASSOCIATION; DISEASE TRANSMISSION; FEMALE; GAMBIA; HEALTH SURVEY; HEPATITIS B VIRUS; HEPATITIS B VIRUS GENOTYPE A; HEPATITIS B VIRUS GENOTYPE E; HUMAN; LIVER CELL CARCINOMA; LIVER FIBROSIS; LONGITUDINAL STUDY; MAJOR CLINICAL STUDY; MALE; MOTHER CHILD RELATION; NONHUMAN; POPULATION RESEARCH; PRACTICE GUIDELINE; PRESCHOOL CHILD; PREVALENCE; PRIORITY JOURNAL; RISK FACTOR; SCHOOL CHILD; YOUNG ADULT; AGED; BLOOD; CARCINOMA, HEPATOCELLULAR; FOLLOW UP; HEPATITIS B, CHRONIC; HETEROZYGOTE; INCIDENCE; INFANT; MIDDLE AGED; PREGNANCY; QUESTIONNAIRE; STATISTICS AND NUMERICAL DATA; TRANSMISSION; VERTICAL TRANSMISSION;

ADOLESCENT; ADULT; AGED; BIOMARKERS; CARCINOMA, HEPATOCELLULAR; CARRIER STATE; CHILD; FEMALE; FOLLOW-UP STUDIES; GAMBIA; HEPATITIS B E ANTIGENS; HEPATITIS B SURFACE ANTIGENS; HEPATITIS B, CHRONIC; HUMANS; INCIDENCE; INFANT; INFECTIOUS DISEASE TRANSMISSION, VERTICAL; LONGITUDINAL STUDIES; MALE; MIDDLE AGED; PREGNANCY; PREVALENCE; RISK FACTORS; SURVEYS AND QUESTIONNAIRES;

EID: 84937598806     PISSN: 00175749     EISSN: 14683288     Source Type: Journal    
DOI: 10.1136/gutjnl-2015-309892     Document Type: Article

References (50)

1. Cowie BC, MacLachlan JH. The global burden of liver disease attributable to hepatitis B, hepatitis C, and alcohol: increasing mortality, differing causes. Hepatology 2013;58:218A-19A.
2. Kiire CF. The epidemiology and prophylaxis of hepatitis B in sub-Saharan Africa: a view from tropical and subtropical Africa. Gut 1996;38:S5-12.
3. WHO. Guidelines for the prevention, care and treatment of persons with chronic hepatitis B infection. Geneva, Switzerland: WHO, 2015.
4. Mendy M, Peterson I, Hossin S, et al. Observational study of vaccine efficacy 24 years after the start of hepatitis B vaccination in two Gambian villages: no need for a booster dose. PLoS One 2013;8:e58029.
5. WHO. Hepatitis B vaccines. WHO position paper. Wkly Epidemiol Rec 2009;84:405-20.
6. Edmunds WJ, Medley GF, Nokes DJ, et al. Epidemiological patterns of hepatitis B virus (HBV) in highly endemic areas. Epidemiol Infect 1996;117:313-25.
7. Chang M-H. Natural history and clinical management of chronic hepatitis B virus infection in children. Hepatol Int 2008;2:S28-36.
8. Shimakawa Y, Yan H-J, Tsuchiya N, et al. Association of early age at establishment of chronic hepatitis B infection with persistent viral replication, liver cirrhosis and hepatocellular carcinoma: a systematic review. PLoS ONE 2013;8:e69430.
9. Shimakawa Y, Lemoine M, Bottomley C, et al. Birth order and risk of hepatocellular carcinoma in chronic carriers of hepatitis B virus: a case-control study in The Gambia. Liver Int Published Online First: 26 Feb 2015. doi:10.1111/liv.12814.
10. European Association for the Study of the Liver. EASL clinical practice guidelines: Management of chronic hepatitis B virus infection. J Hepatol 2012;57:167-85.
11. McGregor IA. Health and communicable disease in a rural African environment. Oikos 1976;27:180-92.
12. Whittle HC, Bradley AK, McLauchlan K, et al. Hepatitis B virus infection in two Gambian villages. Lancet 1983;1:1203-6.
13. Whittle HC, Inskip H, Bradley AK, et al. The pattern of childhood hepatitis B infection in two Gambian villages. J Infect Dis 1990;161:1112-15.
14. Whittle HC, Inskip H, Hall AJ, et al. Vaccination against hepatitis B and protection against chronic viral carriage in The Gambia. Lancet 1991;337:747-50.
15. Whittle HC, Pilkington J, Maine N, et al. Long-term efficacy of continuing hepatitis B vaccination in infancy in two Gambian villages. Lancet 1995;345:1089-92.
16. Whittle HC, Jaffar S, Wansbrough M, et al. Observational study of vaccine efficacy 14 years after trial of hepatitis B vaccination in Gambian children. BMJ 2002;325:569.
17. Van der Sande MAB, Waight P, Mendy M, et al. Long-term protection against carriage of hepatitis B virus after infant vaccination. J Infect Dis 2006;193:1528-35.
18. Shimakawa Y, Lemoine M, Mendy M, et al. Population-based interventions to reduce the public health burden related with hepatitis B virus infection in The Gambia, West Africa. Trop Med Health 2014;42:59-64.
19. Bedossa P, Poynard T. An algorithm for the grading of activity in chronic hepatitis C. Hepatology 1996;24:289-93.
20. Mendy ME, McConkey SJ, van der Sande MAB, et al. Changes in viral load and HBsAg and HBeAg status with age in HBV chronic carriers in The Gambia. Virol J 2008;5:49.
21. Njai HF, Shimakawa Y, Sanneh B, et al. Validation of rapid point-of-care (POC) tests for the detection of hepatitis B surface antigen (HBsAg) in field and laboratory settings in The Gambia, West Africa. J Clin Microbiol 2015;53:1156-63.
22. Mendy ME, Kaye S, van der Sande M, et al. Application of real-time PCR to quantify hepatitis B virus DNA in chronic carriers in The Gambia. Virol J 2006;3:23.
23. Villar S, Le Roux-Goglin E, Gouas DA, et al. Seasonal variation in TP53 R249S-mutated serum DNA with aflatoxin exposure and hepatitis B virus infection. Environ Health Perspect 2011;119:1635-40.
24. Schur N, Hürlimann E, Garba A, et al. Geostatistical Model-Based Estimates of Schistosomiasis Prevalence among Individuals Aged 20 Years in West Africa. PLoS Negl Trop Dis 2011;5:e1194.
25. Lemoine M, Shimakawa Y, Nayagam S, et al. The Gamma-glutamyl transpeptidase to Platelet Ratio (GPR) predicts significant liver fibrosis and cirrhosis in patients with chronic hepatitis B virus infection in West Africa. Gut Published Online First: 24 Jun 2015. doi.org/10.1136/gutjnl-2015-309260
26. Lok ASF, McMahon BJ. Chronic hepatitis B: update 2009. Hepatology 2009;50:661-2.
27. Bah E, Carrieri MP, Hainaut P, et al. 20-years of population-based cancer registration in hepatitis B and liver cancer prevention in the Gambia, West Africa. PLoS ONE 2013;8:e75775.
28. MRC Unit The Gambia. The West Kiang Demographic Surveillance System (DSS). http://www.mrc.gm/our-research/themes/nutrition/ing-research-areas/west-kiang-demographic-surveillance-system-dss/ (accessed 20 Mar 2015).
29. Rothman KJ, Greenland S, Lash TL. Modern Epidemiology. US: Lippincott Williams & Wilkins, 2008.
30. Hyams KC. Risks of chronicity following acute hepatitis b virus infection: a review. Clin Infect Dis 1995;20:992-1000.
31. Lin X, Robinson NJ, Thursz M, et al. Chronic hepatitis B virus infection in the Asia-Pacific region and Africa: review of disease progression. J Gastroenterol Hepatol 2005;20:833-43.
32. Hadziyannis SJ. Natural history of chronic hepatitis B in Euro-Mediterranean and African countries. J Hepatol 2011;55:183-91.
33. Crook PD, Jones ME, Hall AJ. Mortality of hepatitis B surface antigen-positive blood donors in England and Wales. Int J Epidemiol 2003;32:118-24.
34. Lim TH, Gane E, Moyes C, et al. Serological and clinical outcomes of horizontally transmitted chronic hepatitis B infection in New Zealand Māori: results from a 28-year follow-up study. Gut 2015;64:966-72.
35. Evans A, Connell APO, Pugh JC, et al. Geographic variation in viral load among hepatitis B carriers with differing risks of hepatocellular carcinoma. Cancer Epidemiol Biomarkers Prev 1998;7:559-65.
36. Chen CJ, Yang HI, Su J, et al. Risk of hepatocellular carcinoma across a biological gradient of serum hepatitis B virus DNA level. JAMA 2006;295:65-73.
37. Chen C, Lee W, Yang H, et al. Changes in serum levels of HBV DNA and alanine aminotransferase determine risk for hepatocellular carcinoma. Gastroenterology 2011;141:1240-8.
38. Chen YC, Chu CM, Liaw YF. Age-specific prognosis following spontaneous hepatitis B e antigen seroconversion in chronic hepatitis B. Hepatology 2010;51:435-44.
39. Chu CM, Liaw YF. Chronic hepatitis B virus infection acquired in childhood: special emphasis on prognostic and therapeutic implication of delayed HBeAg seroconversion. J Viral Hepat 2007;14:147-52.
40. Shimakawa Y, Bottomley C, Njie R, et al. The association between maternal hepatitis B e antigen status, as a proxy for perinatal transmission, and the risk of hepatitis B e antigenaemia in Gambian children. BMC Public Health 2014;14:532.
41. Peto TJ, Mendy ME, Lowe Y, et al. Efficacy and effectiveness of infant vaccination against chronic hepatitis B in the Gambia Hepatitis Intervention Study (1986-90) and in the nationwide immunisation program. BMC Infect Dis 2014;14:7.
42. WHO. Global routine vaccination coverage, 2013. Wkly Epidemiol Rec 2014;89:517-22.
43. Howell J, Lemoine M, Thursz M. Prevention of materno-foetal transmission of hepatitis B in sub-Saharan Africa: the evidence, current practice and future challenges. J Viral Hepat 2014;21:381-96.
44. Kramvis A, Kew MC. Epidemiology of hepatitis B virus in Africa, its genotypes and clinical associations of genotypes. Hepatol Res 2007;37:S9-19.
45. Livingston SE, Simonetti JP, Bulkow LR, et al. Clearance of hepatitis B e antigen in patients with chronic hepatitis B and genotypes A, B, C, D, and F. Gastroenterology 2007;133:1452-7.
46. Kew MC, Geddes EW. Hepatocellular carcinoma in rural southern African blacks. Medicine (Baltimore) 1982;61:98-108.
47. McMahon BJ, Holck P, Bulkow L, et al. Serologic and clinical outcomes of 1536 Alaska Natives chronically infected with hepatitis B virus. Ann Intern Med 2001;135:759-68.
48. Bortolotti F, Guido M, Bartolacci S, et al. Chronic hepatitis B in children after e antigen seroclearance: final report of a 29-year longitudinal study. Hepatology 2006;43:556-62.
49. Sanlidag T, Akcali S, Ozbakkaloglu B. Serum hepatitis B DNA: Stability in relation to multiple freeze-thaw procedures. J Virol Methods 2005;123: 49-52.
50. Shimakawa Y, Bah E, Wild CP, et al. Evaluation of data quality at the Gambia National Cancer Registry. Int J Cancer 2013;132:658-65.