Development of Asthmatic Response upon Bronchial Allergen Challenge Is Associated with Dynamic Changes of Interleukin-10-Producing and Interleukin-10-Responding CD4+ T Cells

Inflammation

Volumn 37, Issue 6, 2014, Pages 1945-1956

  Moniuszko, Marcin ^a   Grubczak, Kamil ^a   Kowal, Krzysztof ^a   Eljaszewicz, Andrzej ^a   Rusak, Malgorzata ^a   Jeznach, Marta ^a   Jablonska, Ewa ^a   Dabrowska, Milena ^a   Bodzenta Lukaszyk, Anna ^a  

^a MEDICAL UNIVERSITY OF BIALYSTOK   (Poland)

Author keywords

allergen challenge; asthma; interleukin 10; interleukin 7 receptor; interlukin 10 receptor; regulatory T cells

Indexed keywords

ALLERGEN; BIOLOGICAL MARKER; HOUSE DUST ALLERGEN; IL10 PROTEIN, HUMAN; INTERLEUKIN 10;

ASTHMA; BLOOD; CD4+ T LYMPHOCYTE; CELL CULTURE; CHEMICALLY INDUCED; HUMAN; INHALATION TEST; INHALATIONAL DRUG ADMINISTRATION; METABOLISM; PROCEDURES;

ADMINISTRATION, INHALATION; ALLERGENS; ANTIGENS, DERMATOPHAGOIDES; ASTHMA; BIOLOGICAL MARKERS; BRONCHIAL PROVOCATION TESTS; CD4-POSITIVE T-LYMPHOCYTES; CELLS, CULTURED; HUMANS; INTERLEUKIN-10;

EID: 84937559813     PISSN: 03603997     EISSN: 15732576     Source Type: Journal    
DOI: 10.1007/s10753-014-9927-9     Document Type: Article

References (24)

1. Robinson, D.S. 2009. Regulatory T-cells and asthma. Clinical and Experimental Immunology 39(9): 1314–1323.
2. Moniuszko, M., K. Kowal, S. Zukowski, M. Dabrowska, and A. Bodzenta-Lukaszyk. 2008. Frequencies of circulating CD4+CD25+CD127low cells in atopics are altered by bronchial allergen challenge. European Journal of Clinical Investigation 38(3): 201–204.
3. Muratov, V., C. Barck, G. Bylin, E. Källström, G. Halldén, M. van Hage, K. Elvin, and J. Lundahl. 2005. Allergen challenge alters intracellular cytokine expression. Scandinavian Journal of Immunology 62(2): 161–167.
4. Matsumoto, K., G.M. Gauvreau, T. Rerecich, R.M. Watson, L.J. Wood, and P.M. O’Byrne. 2002. IL-10 production in circulating T-cells differs between allergen-induced isolated early and dual asthmatic responders. Journal of Allergy and Clinical Immunology 109(2): 281–286.
5. Liu, W., A.L. Putnam, Z. Xu-Yu, et al. 2006. CD127 expression inversely correlates with FoxP3 and suppressive function of human CD4+ T reg cells. Journal of Experimental Medicine 203(7): 1701–1711.
6. Seddiki, N., B. Santner-Nanan, J. Martinson, et al. 2006. Expression of interleukin (IL)-2 and IL-7 receptors discriminates between human regulatory and activated T-cells. Journal of Experimental Medicine 203(7): 1693–1700.
7. Moniuszko, M., B. Glowinska-Olszewska, M. Rusak, M. Jeznach, K. Grubczak, D. Lipinska, et al. 2013. Decreased CD127 expression on CD4+ T-cells and elevated frequencies of CD4+CD25+CD127− T-cells in children with long-lasting type 1 diabetes. Clinical and Developmental Immunology. doi:10.1155/2013/459210.
8. Couper, K.N., D.G. Blount, M.S. Wilson, et al. 2008. IL-10 from CD4+CD25−Foxp3−CD127− adaptive regulatory T-cells modulates parasite clearance and pathology during malaria infection. PLoS Pathogen 4(2): e1000004.
9. Mays, L.E., S. Ammon-Treiber, B. Mothes, et al. 2013. Modified Foxp3 mRNA protects against asthma through an IL-10-dependent mechanism. Journal of Clinical Investigation 123(3): 1216–1228.
10. Kosaka, S., H. Tamauchi, M. Terashima, H. Maruyama, S. Habu, and H. Kitasato. 2011. IL-10 controls Th2-type cytokine production and eosinophil infiltration in a mouse model of allergic airway inflammation. Immunobiology 216(7): 811–820.
11. Banham, A.H. 2006. Cell-surface IL-7 receptor expression facilitates the purification of FOXP3(+) regulatory T-cells. Trends in Immunology 27(12): 541–544.
12. Moniuszko, M., A. Bodzenta-Lukaszyk, and M. Dabrowska. 2010. Effects of oral glucocorticoid therapy on CD4+CD25+CD127− and CD4+CD25high T-cell levels in asthmatic patients. Inflammation 33: 415–420.
13. Moniuszko, M., A. Bodzenta-Lukaszyk, and M. Dabrowska. 2009. Oral glucocorticoid treatment decreases interleukin-10 receptor expression on peripheral blood leucocyte subsets. Clinical and Experimental Immunology 156: 328–335.
14. McClymont, S.A., A.L. Putnam, M.R. Lee, et al. 2011. Plasticity of human regulatory T-cells in healthy subjects and patients with type 1 diabetes. Journal of Immunology 186(7): 3918–3926.
15. Murphy, K.M., and B. Stockinger. 2010. Effector T-cell plasticity: Flexibility in the face of changing circumstances. Nature Immunology 11(8): 674–680.
16. Hegazy, A.N., M. Peine, C. Helmstetter, et al. 2010. Interferons direct Th2 cell reprogramming to generate a stable GATA-3(+)T-bet(+) cell subset with combined Th2 and Th1 cell functions. Immunity 32(1): 116–128.
17. Wei, G., L. Wei, J. Zhu, et al. 2009. Global mapping of H3K4me3 and H3K27me3 reveals specificity and plasticity in lineage fate determination of differentiating CD4+ T-cells. Immunity 30(1): 155–167.
18. Rosloniec, E.F., K. Latham, and Y.B. Guedez. 2002. Paradoxical roles of IFN-gamma in models of Th1-mediated autoimmunity. Arthritis Research 4(6): 333–336.
19. Boulet, L.P., G. Gauvreau, M.E. Boulay, P. O’Byrne, D.W. Cockcroft, and Clinical Investigative Collaboration, Canadian Network of Centers of Excellence AllerGen. 2007. The allergen bronchoprovocation model: an important tool for the investigation of new asthma anti-inflammatory therapies. Allergy 62(10): 1101–1110.
20. Cockcroft, D.W., F.E. Hargreave, P.M. O’Byrne, and L.P. Boulet. 2007. Understanding allergic asthma from allergen inhalation tests. Canadian Respiratory Journal 14(7): 414–418.
21. Diamant, Z., G.M. Gauvreau, D.W. Cockcroft, L.P. Boulet, P.J. Sterk, F.H. de Jongh, B. Dahlén, and P.M. O’Byrne. 2013. Inhaled allergen bronchoprovocation tests. Journal of Allergy and Clinical Immunology 132(5): 1045–1055.
22. Kowal, K., M. Moniuszko, M. Dabrowska, and A. Bodzenta-Lukaszyk. 2012. Allergen challenge differentially affects the number of circulating monocyte subsets. Scandinavian Journal of Immunology 75(5): 531–539.
23. Lu, M., W. Dawicki, X. Zhang, H. Huang, A. Nayyar, and J.R. Gordon. 2011. Therapeutic induction of tolerance by IL-10-differentiated dendritic cells in a mouse model of house dust mite-asthma. Allergy 66(5): 612–620.
24. Nayyar, A., W. Dawicki, H. Huang, M. Lu, X. Zhang, and J.R. Gordon. 2012. Induction of prolonged asthma tolerance by IL-10-differentiated dendritic cells: Differential impact on airway hyperresponsiveness and the Th2 immunoinflammatory response. Journal of Immunology 189(1): 72–79.