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Volumn 33, Issue 8, 2015, Pages 338.e9-338.e17

Organized metabolic crime in prostate cancer: The coexpression of MCT1 in tumor and MCT4 in stroma is an independent prognosticator for biochemical failure

Author keywords

MCT1; MCT4; Monocarboxylate transporter; Prostate cancer; Stroma

Indexed keywords

BIOLOGICAL MARKER; LACTIC ACID; MONOCARBOXYLATE TRANSPORTER 1; MONOCARBOXYLATE TRANSPORTER 4; COTRANSPORTER; MONOCARBOXYLATE TRANSPORT PROTEIN 1; MONOCARBOXYLATE TRANSPORTER; MUSCLE PROTEIN; SLC16A4 PROTEIN, HUMAN; TUMOR MARKER;

EID: 84937523781     PISSN: 10781439     EISSN: 18732496     Source Type: Journal    
DOI: 10.1016/j.urolonc.2015.05.013     Document Type: Article
Times cited : (27)

References (37)
  • 1
    • 84881609784 scopus 로고    scopus 로고
    • Defining the threshold for significant versus insignificant prostate cancer
    • van der Kwast T.H., Roobol M.J. Defining the threshold for significant versus insignificant prostate cancer. Nat Rev Urol 2013, 10:473-482.
    • (2013) Nat Rev Urol , vol.10 , pp. 473-482
    • van der Kwast, T.H.1    Roobol, M.J.2
  • 3
    • 84896466669 scopus 로고    scopus 로고
    • Screening for prostate cancer with the prostate-specific antigen test: a review of current evidence
    • Hayes J.H., Barry M.J. Screening for prostate cancer with the prostate-specific antigen test: a review of current evidence. J Am Med Assoc 2014, 311:1143-1149.
    • (2014) J Am Med Assoc , vol.311 , pp. 1143-1149
    • Hayes, J.H.1    Barry, M.J.2
  • 4
    • 84887444879 scopus 로고    scopus 로고
    • Microenvironmental regulation of tumor progression and metastasis
    • Quail D.F., Joyce J.A. Microenvironmental regulation of tumor progression and metastasis. Nat Med 2013, 19:1423-1437.
    • (2013) Nat Med , vol.19 , pp. 1423-1437
    • Quail, D.F.1    Joyce, J.A.2
  • 5
    • 84896722500 scopus 로고    scopus 로고
    • Tumor-stroma metabolic relationship based on lactate shuttle can sustain prostate cancer progression
    • Sanita P., Capulli M., Teti A., Galatioto G.P., Vicentini C., Chiarugi P., et al. Tumor-stroma metabolic relationship based on lactate shuttle can sustain prostate cancer progression. BMC Cancer 2014, 14:154.
    • (2014) BMC Cancer , vol.14 , pp. 154
    • Sanita, P.1    Capulli, M.2    Teti, A.3    Galatioto, G.P.4    Vicentini, C.5    Chiarugi, P.6
  • 6
    • 79952284127 scopus 로고    scopus 로고
    • Hallmarks of cancer: the next generation
    • Hanahan D., Weinberg R.A. Hallmarks of cancer: the next generation. Cell 2011, 144:646-674.
    • (2011) Cell , vol.144 , pp. 646-674
    • Hanahan, D.1    Weinberg, R.A.2
  • 7
    • 12444279265 scopus 로고
    • On the origin of cancer cells
    • Warburg O. On the origin of cancer cells. Science 1956, 123:309-314.
    • (1956) Science , vol.123 , pp. 309-314
    • Warburg, O.1
  • 8
    • 57449097020 scopus 로고    scopus 로고
    • Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice
    • Sonveaux P., Vegran F., Schroeder T., Wergin M.C., Verrax J., Rabbani Z.N., et al. Targeting lactate-fueled respiration selectively kills hypoxic tumor cells in mice. J Clin Invest 2008, 118:3930-3942.
    • (2008) J Clin Invest , vol.118 , pp. 3930-3942
    • Sonveaux, P.1    Vegran, F.2    Schroeder, T.3    Wergin, M.C.4    Verrax, J.5    Rabbani, Z.N.6
  • 9
    • 84867112200 scopus 로고    scopus 로고
    • Reciprocal metabolic reprogramming through lactate shuttle coordinately influences tumor-stroma interplay
    • Fiaschi T., Marini A., Giannoni E., Taddei M.L., Gandellini P., De D.A., et al. Reciprocal metabolic reprogramming through lactate shuttle coordinately influences tumor-stroma interplay. Cancer Res 2012, 72:5130-5140.
    • (2012) Cancer Res , vol.72 , pp. 5130-5140
    • Fiaschi, T.1    Marini, A.2    Giannoni, E.3    Taddei, M.L.4    Gandellini, P.5    De, D.A.6
  • 10
    • 84907833339 scopus 로고    scopus 로고
    • Lactate transporters in the context of prostate cancer metabolism: what do we know?
    • Pertega-Gomes N., Baltazar F. Lactate transporters in the context of prostate cancer metabolism: what do we know?. Int J Mol Sci 2014, 15:18333-18348.
    • (2014) Int J Mol Sci , vol.15 , pp. 18333-18348
    • Pertega-Gomes, N.1    Baltazar, F.2
  • 11
    • 84858120137 scopus 로고    scopus 로고
    • Targeting the lactate transporter MCT1 in endothelial cells inhibits lactate-induced HIF-1 activation and tumor angiogenesis
    • Sonveaux P., Copetti T., De Saedeleer C.J., Vegran F., Verrax J., Kennedy K.M., et al. Targeting the lactate transporter MCT1 in endothelial cells inhibits lactate-induced HIF-1 activation and tumor angiogenesis. PLoS One 2012, 7:e33418.
    • (2012) PLoS One , vol.7 , pp. e33418
    • Sonveaux, P.1    Copetti, T.2    De Saedeleer, C.J.3    Vegran, F.4    Verrax, J.5    Kennedy, K.M.6
  • 12
    • 84871706742 scopus 로고    scopus 로고
    • Carbohydrate restriction and lactate transporter inhibition in a mouse xenograft model of human prostate cancer
    • Kim H.S., Masko E.M., Poulton S.L., Kennedy K.M., Pizzo S.V., Dewhirst M.W., et al. Carbohydrate restriction and lactate transporter inhibition in a mouse xenograft model of human prostate cancer. BJU Int 2012, 110:1062-1069.
    • (2012) BJU Int , vol.110 , pp. 1062-1069
    • Kim, H.S.1    Masko, E.M.2    Poulton, S.L.3    Kennedy, K.M.4    Pizzo, S.V.5    Dewhirst, M.W.6
  • 13
    • 79960587072 scopus 로고    scopus 로고
    • Monocarboxylate transporter 4 (MCT4) and CD147 overexpression is associated with poor prognosis in prostate cancer
    • Pertega-Gomes N., Vizcaino J.R., Miranda-Goncalves V., Pinheiro C., Silva J., Pereira H., et al. Monocarboxylate transporter 4 (MCT4) and CD147 overexpression is associated with poor prognosis in prostate cancer. BMC Cancer 2011, 11:312.
    • (2011) BMC Cancer , vol.11 , pp. 312
    • Pertega-Gomes, N.1    Vizcaino, J.R.2    Miranda-Goncalves, V.3    Pinheiro, C.4    Silva, J.5    Pereira, H.6
  • 14
    • 84901597401 scopus 로고    scopus 로고
    • A lactate shuttle system between tumour and stromal cells is associated with poor prognosis in prostate cancer
    • Pertega-Gomes N., Vizcaino J.R., Attig J., Jurmeister S., Lopes C., Baltazar F. A lactate shuttle system between tumour and stromal cells is associated with poor prognosis in prostate cancer. BMC Cancer 2014, 14:352.
    • (2014) BMC Cancer , vol.14 , pp. 352
    • Pertega-Gomes, N.1    Vizcaino, J.R.2    Attig, J.3    Jurmeister, S.4    Lopes, C.5    Baltazar, F.6
  • 15
    • 84907227069 scopus 로고    scopus 로고
    • Monocarboxylate transporters 1-4 in NSCLC: MCT1 is an independent prognostic marker for survival
    • Eilertsen M., Andersen S., Al-Saad S., Kiselev Y., Donnem T., Stenvold H., et al. Monocarboxylate transporters 1-4 in NSCLC: MCT1 is an independent prognostic marker for survival. PLoS One 2014, 9:e105038.
    • (2014) PLoS One , vol.9 , pp. e105038
    • Eilertsen, M.1    Andersen, S.2    Al-Saad, S.3    Kiselev, Y.4    Donnem, T.5    Stenvold, H.6
  • 16
    • 84902052886 scopus 로고    scopus 로고
    • Disease-specific outcomes of radical prostatectomies in Northern Norway; a case for the impact of perineural infiltration and postoperative PSA-doubling time
    • Andersen S., Richardsen E., Nordby Y., Ness N., Storkersen O., Al-Shibli K., et al. Disease-specific outcomes of radical prostatectomies in Northern Norway; a case for the impact of perineural infiltration and postoperative PSA-doubling time. BMC Urol 2014, 14:49.
    • (2014) BMC Urol , vol.14 , pp. 49
    • Andersen, S.1    Richardsen, E.2    Nordby, Y.3    Ness, N.4    Storkersen, O.5    Al-Shibli, K.6
  • 17
  • 19
    • 0031731776 scopus 로고    scopus 로고
    • Evidence supporting the existence of an activity-dependent astrocyte-neuron lactate shuttle
    • Pellerin L., Pellegri G., Bittar P.G., Charnay Y., Bouras C., Martin J.L., et al. Evidence supporting the existence of an activity-dependent astrocyte-neuron lactate shuttle. Dev Neurosci 1998, 20:291-299.
    • (1998) Dev Neurosci , vol.20 , pp. 291-299
    • Pellerin, L.1    Pellegri, G.2    Bittar, P.G.3    Charnay, Y.4    Bouras, C.5    Martin, J.L.6
  • 20
    • 34250791536 scopus 로고    scopus 로고
    • Oxidative metabolism of pyruvate is required for meiotic maturation of murine oocytes in vivo
    • Johnson M.T., Freeman E.A., Gardner D.K., Hunt P.A. Oxidative metabolism of pyruvate is required for meiotic maturation of murine oocytes in vivo. Biol Reprod 2007, 77:2-8.
    • (2007) Biol Reprod , vol.77 , pp. 2-8
    • Johnson, M.T.1    Freeman, E.A.2    Gardner, D.K.3    Hunt, P.A.4
  • 21
    • 84867513461 scopus 로고    scopus 로고
    • Blood flow and oxygenation status of prostate cancers
    • Vaupel P., Kelleher D.K. Blood flow and oxygenation status of prostate cancers. Adv Exp Med Biol 2013, 765:299-305.
    • (2013) Adv Exp Med Biol , vol.765 , pp. 299-305
    • Vaupel, P.1    Kelleher, D.K.2
  • 22
    • 77954162846 scopus 로고    scopus 로고
    • Oxidative stress in cancer associated fibroblasts drives tumor-stroma co-evolution: a new paradigm for understanding tumor metabolism, the field effect and genomic instability in cancer cells
    • Martinez-Outschoorn U.E., Balliet R.M., Rivadeneira D.B., Chiavarina B., Pavlides S., Wang C., et al. Oxidative stress in cancer associated fibroblasts drives tumor-stroma co-evolution: a new paradigm for understanding tumor metabolism, the field effect and genomic instability in cancer cells. Cell Cycle 2010, 9:3256-3276.
    • (2010) Cell Cycle , vol.9 , pp. 3256-3276
    • Martinez-Outschoorn, U.E.1    Balliet, R.M.2    Rivadeneira, D.B.3    Chiavarina, B.4    Pavlides, S.5    Wang, C.6
  • 23
    • 25144464638 scopus 로고    scopus 로고
    • Comparison of hypoxia transcriptome in vitro with in vivo gene expression in human bladder cancer
    • Ord J.J., Streeter E.H., Roberts I.S., Cranston D., Harris A.L. Comparison of hypoxia transcriptome in vitro with in vivo gene expression in human bladder cancer. Br J Cancer 2005, 93:346-354.
    • (2005) Br J Cancer , vol.93 , pp. 346-354
    • Ord, J.J.1    Streeter, E.H.2    Roberts, I.S.3    Cranston, D.4    Harris, A.L.5
  • 26
    • 84928104604 scopus 로고    scopus 로고
    • Effect of mitochondrial metabolism-interfering agents on cancer cell mitochondrial function and radio/chemosensitivity
    • Mitrakas A.G., Kalamida D., Koukourakis M.I. Effect of mitochondrial metabolism-interfering agents on cancer cell mitochondrial function and radio/chemosensitivity. Anticancer Drugs 2014, 25:1182-1191.
    • (2014) Anticancer Drugs , vol.25 , pp. 1182-1191
    • Mitrakas, A.G.1    Kalamida, D.2    Koukourakis, M.I.3
  • 27
    • 85027930040 scopus 로고    scopus 로고
    • Metabolomics approaches and applications in prostate cancer research
    • Zhang A., Yan G., Han Y., Wang X. Metabolomics approaches and applications in prostate cancer research. Appl Biochem Biotechnol 2014, 174:6-12.
    • (2014) Appl Biochem Biotechnol , vol.174 , pp. 6-12
    • Zhang, A.1    Yan, G.2    Han, Y.3    Wang, X.4
  • 28
    • 84884325809 scopus 로고    scopus 로고
    • Cancer metabolism: new validated targets for drug discovery
    • Sotgia F., Martinez-Outschoorn U.E., Lisanti M.P. Cancer metabolism: new validated targets for drug discovery. Oncotarget 2013, 4:1309-1316.
    • (2013) Oncotarget , vol.4 , pp. 1309-1316
    • Sotgia, F.1    Martinez-Outschoorn, U.E.2    Lisanti, M.P.3
  • 30
    • 84963693734 scopus 로고    scopus 로고
    • The effect of dietary and exercise interventions on body weight in prostate cancer patients: a systematic review
    • Mohamad H., McNeill G., Haseen F., N'Dow J., Craig L.C., Heys S.D. The effect of dietary and exercise interventions on body weight in prostate cancer patients: a systematic review. Nutr Cancer 2014, 25:1-18.
    • (2014) Nutr Cancer , vol.25 , pp. 1-18
    • Mohamad, H.1    McNeill, G.2    Haseen, F.3    N'Dow, J.4    Craig, L.C.5    Heys, S.D.6
  • 32
    • 84910062391 scopus 로고    scopus 로고
    • Nutrition and prostate cancer: an overview
    • Patel V.H. Nutrition and prostate cancer: an overview. Expert Rev Anticancer Ther 2014, 14:1295-1304.
    • (2014) Expert Rev Anticancer Ther , vol.14 , pp. 1295-1304
    • Patel, V.H.1
  • 33
    • 84875208817 scopus 로고    scopus 로고
    • The effect of carbohydrate restriction on prostate cancer tumor growth in a castrate mouse xenograft model
    • Caso J., Masko E.M., Ii J.A., Poulton S.H., Dewhirst M., Pizzo S.V., et al. The effect of carbohydrate restriction on prostate cancer tumor growth in a castrate mouse xenograft model. Prostate 2013, 73:449-454.
    • (2013) Prostate , vol.73 , pp. 449-454
    • Caso, J.1    Masko, E.M.2    Ii, J.A.3    Poulton, S.H.4    Dewhirst, M.5    Pizzo, S.V.6
  • 35
    • 84879823339 scopus 로고    scopus 로고
    • The role of physical activity in cancer prevention, treatment, recovery, and survivorship
    • Lemanne D., Cassileth B., Gubili J. The role of physical activity in cancer prevention, treatment, recovery, and survivorship. Oncology (Williston Park) 2013, 27:580-585.
    • (2013) Oncology (Williston Park) , vol.27 , pp. 580-585
    • Lemanne, D.1    Cassileth, B.2    Gubili, J.3
  • 36
    • 84866772958 scopus 로고    scopus 로고
    • Physical activity and urologic cancers
    • Wolin K.Y., Stoll C. Physical activity and urologic cancers. Urol Oncol 2012, 30:729-734.
    • (2012) Urol Oncol , vol.30 , pp. 729-734
    • Wolin, K.Y.1    Stoll, C.2
  • 37
    • 84899713732 scopus 로고    scopus 로고
    • Tumor microenvironment and metabolic synergy in breast cancers: critical importance of mitochondrial fuels and function
    • Martinez-Outschoorn U., Sotgia F., Lisanti M.P. Tumor microenvironment and metabolic synergy in breast cancers: critical importance of mitochondrial fuels and function. Semin Oncol 2014, 41:195-216.
    • (2014) Semin Oncol , vol.41 , pp. 195-216
    • Martinez-Outschoorn, U.1    Sotgia, F.2    Lisanti, M.P.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.