Structure and function of SemiSWEET and SWEET sugar transporters

Trends in Biochemical Sciences

Volumn 40, Issue 8, 2015, Pages 480-486

  Feng, Liang ^a   Frommer, Wolf B ^b  

^a STANFORD UNIVERSITY SCHOOL OF MEDICINE   (United States)

^b GEOPHYSICAL LABORATORY   (United States)

Author keywords

Carrier; Crystal structure; Fructose; Glucose; Hexose; Sucrose

Indexed keywords

HEXOSE; SEMISWEET PROTEIN; SUCROSE; SWEET PROTEIN; UNCLASSIFIED DRUG; CARRIER PROTEIN;

ARABIDOPSIS; BINDING SITE; BRASSICA; CAENORHABDITIS ELEGANS; CASSAVA; CRYSTAL STRUCTURE; DIMERIZATION; EUKARYOTE; GLUCOSE TRANSPORT; HUMAN; MOLECULAR EVOLUTION; NICOTIANA; NONHUMAN; PLANT PATHOGEN INTERACTION; PRIORITY JOURNAL; PROKARYOTE; PROTEIN BINDING; PROTEIN CONFORMATION; PROTEIN FUNCTION; PROTEIN STRUCTURE; REVIEW; RICE; SUGAR TRANSPORT; SWEET11 GENE; SWEET12 GENE; SWEET13 GENE; SWEET15 GENE; SWEET16 GENE; SWEET17 GENE; SWEET8 GENE; SWEET9 GENE; THERMODESULFOVIBRIO YELLOWSTONII; TRIPLE HELIX; TRIPLE HELIX BUNDLE; VIBRIO; XANTHOMONAS ORYZAE PV. ORYZAE; ANIMAL; CHEMICAL STRUCTURE; CHEMISTRY; METABOLISM; TRANSPORT AT THE CELLULAR LEVEL;

ANIMALIA; BACTERIA (MICROORGANISMS); EUKARYOTA; PROKARYOTA;

ANIMALS; BIOLOGICAL TRANSPORT; HEXOSES; HUMANS; MEMBRANE TRANSPORT PROTEINS; MODELS, MOLECULAR; PROTEIN CONFORMATION;

EID: 84937522071     PISSN: 09680004     EISSN: 13624326     Source Type: Journal    
DOI: 10.1016/j.tibs.2015.05.005     Document Type: Review

References (33)

1. Chen L-Q., et al. Transport of sugars. Annu. Rev. Biochem. 2015, 84:1-20.
2. Chaptal V., et al. Crystal structure of lactose permease in complex with an affinity inactivator yields unique insight into sugar recognition. Proc. Natl. Acad. Sci. U.S.A. 2011, 108:9361-9366.
3. Eom J.S., et al. SWEETs, transporters for intracellular and intercellular sugar translocation. Curr. Opin. Plant Biol. 2015, 25:53-62.
4. Wright E.M., et al. Biology of human sodium glucose transporters. Physiol. Rev. 2011, 91:733-794.
5. Chen L.Q., et al. Sugar transporters for intercellular exchange and nutrition of pathogens. Nature 2010, 468:527-532.
6. Chen L.Q., et al. Sucrose efflux mediated by SWEET proteins as a key step for phloem transport. Science 2012, 335:207-211.
7. Chen L.Q., et al. Embryo nutrition by a cascade of sequentially expressed sucrose transporters in the seed coat. Plant Cell 2015, 27:607-619.
8. Lin I.W., et al. Nectar secretion requires sucrose phosphate synthases and the sugar transporter SWEET9. Nature 2014, 508:546-549.
9. Xuan Y.H., et al. Functional role of oligomerization for bacterial and plant SWEET sugar transporter family. Proc. Natl. Acad. Sci. U.S.A. 2013, 110:E3685-E3694.
10. Xu Y., et al. Structures of bacterial homologues of SWEET transporters in two distinct conformations. Nature 2014, 515:448-452.
11. Lee Y., et al. Structural basis for the facilitative diffusion mechanism by SemiSWEET transporter. Nat. Commun. 2015, 6:6112.
12. Guan Y.F., et al. RUPTURED POLLEN GRAIN1, a member of the MtN3/saliva gene family, is crucial for exine pattern formation and cell integrity of microspores in Arabidopsis. Plant Physiol. 2008, 147:852-863.
13. Seo P.J., et al. An Arabidopsis senescence-associated protein SAG29 regulates cell viability under high salinity. Planta 2011, 233:189-200.
14. Chardon F., et al. Leaf fructose content is controlled by the vacuolar transporter SWEET17 in Arabidopsis. Curr. Biol. 2013, 23:697-702.
15. Guo W-J., et al. SWEET17, a facilitative transporter, mediates fructose transport across the tonoplast of Arabidopsis roots and leaves. Plant Physiol. 2014, 164:777-789.
16. Klemens P.A., et al. Overexpression of the vacuolar sugar carrier AtSWEET16 modifies germination, growth and stress tolerance in Arabidopsis thaliana. Plant Physiol. 2013, 63:1338-1352.
17. Komarova N.Y., et al. Determinants for Arabidopsis peptide transporter targeting to the tonoplast or plasma membrane. Traffic 2012, 13:1090-1105.
18. Luu D-T., Maurel C. Aquaporin trafficking in plant cells: an emerging membrane-protein model. Traffic 2013, 14:629-635.
19. Streubel J., et al. Five phylogenetically close rice SWEET genes confer TAL effector-mediated susceptibility to Xanthomonas oryzae pv. oryzae. New Phytol. 2013, 200:808-819.
20. Cohn M., et al. Xanthomonas axonopodis virulence is promoted by a Transcription Activator-Like Effector-mediated induction of a SWEET sugar transporter in cassava. Mol. Plant Microbe Interact. 2014, 27:1186-1198.
21. Nicolai M., et al. Gain-of-function screen identifies a role of the Src64 oncogene in Drosophila mushroom body development. J. Neurobiol. 2003, 57:291-302.
22. Wang J., et al. Crystal structure of a bacterial homologue of SWEET transporters. Cell Res. 2014, 24:1486-1489.
23. Yan N. Structural advances for the major facilitator superfamily (MFS) transporters. Trends Biochem. Sci. 2013, 38:151-159.
24. Jaehme M., et al. Crystal structure of the vitamin B3 transporter PnuC, a full-length SWEET homolog. Nat. Struct. Mol. Biol. 2014, 21:1013-1015.
25. Jaehme M., Slotboom D.J. Structure, function, evolution and application of bacterial Pnu-type vitamin transporters. Biol. Chem. 2015, Published online February 24, 2015. 10.1515/hsz-2014-0113.
26. Yee D.C., et al. The transporter-opsin-G protein-coupled receptor (TOG) superfamily. FEBS J. 2013, 280:5780-5800.
27. Keller R., et al. When two turn into one: evolution of membrane transporters from half modules. Biol. Chem. 2014, 395:1379-1388.
28. Sun M.X., et al. Arabidopsis RPG1 is important for primexine deposition and functions redundantly with RPG2 for plant fertility at the late reproductive stage. Plant Reprod. 2013, 26:83-91.
29. Antony G., et al. Rice xa13 recessive resistance to bacterial blight is defeated by induction of the disease susceptibility gene Os-11N3. Plant Cell 2010, 22:3864-3876.
30. Chu Z., et al. Targeting xa13, a recessive gene for bacterial blight resistance in rice. Theor. Appl. Genet. 2006, 112:455-461.
31. Yang B., et al. Os8N3 is a host disease-susceptibility gene for bacterial blight of rice. Proc. Natl. Acad. Sci. U.S.A. 2006, 103:10503-10508.
32. Yuan M., et al. Pathogen-induced expressional loss of function is the key factor in race-specific bacterial resistance conferred by a recessive R gene xa13 in rice. Plant Cell Physiol. 2009, 50:947-955.
33. Hamada M., et al. Ci-Rga, a gene encoding an MtN3/saliva family transmembrane protein, is essential for tissue differentiation during embryogenesis of the ascidian Ciona intestinalis. Differentiation 2005, 73:364-376.