Metabolomic profiles illuminate the efficacy of Chinese herbal Da-Cheng-Qi decoction on acute pancreatitis in rats

Pancreatology

Volumn 15, Issue 4, 2015, Pages 337-343

  Li, Juan ^a   Zhu, Shi Feng ^a   Zhao, Xian Lin ^a   Liu, Yi Xia ^a,b   Wan, Mei Hua ^a   Guo, Hui ^a   Liu, Yi Ling ^a   Gong, Han Lin ^a   Chen, Guang Yuan ^a   Tang, Wen Fu ^a  

^a SICHUAN UNIVERSITY   (China)

^b China Tibetology Research Center   (China)

Author keywords

1HNMR; Acute pancreatitis; CPMG; Da Cheng Qi decoction; Metabolomics; OSC PLS DA analysis

Indexed keywords

ALANINE; CHINESE DRUG; CHOLINE; CREATINE; DA CHENG QI; GLUCOSE; GLUTAMIC ACID; GLUTAMINE; GLYCEROL; GLYCINE; HIGH DENSITY LIPOPROTEIN; LACTIC ACID; LOW DENSITY LIPOPROTEIN CHOLESTEROL; SATURATED FATTY ACID; TAUROCHOLIC ACID; TRIMETHYLAMINE OXIDE; UNCLASSIFIED DRUG; DA-CHENG-QI; FATTY ACID; HERBACEOUS AGENT;

ACUTE PANCREATITIS; ADULT; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; BLOOD ANALYSIS; CHINESE HERB; CHOLESTEROL BLOOD LEVEL; CONCENTRATION (PARAMETERS); CONTROLLED STUDY; DRUG EFFICACY; GLYCEROL BLOOD LEVEL; MALE; METABOLISM; METABOLITE; METABOLOMICS; NONHUMAN; NUCLEAR MAGNETIC RESONANCE SPECTROSCOPY; PRINCIPAL COMPONENT ANALYSIS; PRIORITY JOURNAL; PROTON NUCLEAR MAGNETIC RESONANCE; RAT; ANIMAL; BIOTRANSFORMATION; BLOOD; PANCREATITIS; SPRAGUE DAWLEY RAT;

ALANINE; ANIMALS; BIOTRANSFORMATION; CHOLESTEROL, LDL; DRUGS, CHINESE HERBAL; FATTY ACIDS; GLUTAMIC ACID; GLUTAMINE; GLYCEROL; MAGNETIC RESONANCE SPECTROSCOPY; MALE; METABOLOMICS; PANCREATITIS; RATS; RATS, SPRAGUE-DAWLEY;

EID: 84937521609     PISSN: 14243903     EISSN: 14243911     Source Type: Journal    
DOI: 10.1016/j.pan.2015.04.011     Document Type: Article

References (27)

1. V. Muddana, D.C. Whitcomb, and G.I. Papachristou Current management and novel insights in acute pancreatitis Expert Rev Gastroenterol Hepatol 3 2009 435 444
2. P.A. Banks, D.L. Conwell, and P.P. Toskes The management of acute and chronic pancreatitis Gastroenterol Hepatol 6 Suppl. 2 2010 1 16
3. Q. Xia, L. Yuan, X.N. Yang, W.F. Tang, and J.M. Jiang Comparison of integrated Chinese and western medicine with and without somatostatin supplement in the treatment of severe acute pancreatitis World J Gastroenterol 11 2005 1073 1076
4. L.H. Deng, D.K. Xiang, P. Xue, H.Y. Zhang, L. Huang, and Q. Xia Effects of Chai-Qin-Cheng-Qi decoction on cefotaxime in rats with acute necrotizing pancreatitis World J Gastroenterol 15 2009 4439 4443
5. M.J. Zhang, G.L. Zhang, W.B. Yuan, J. Ni, and L.F. Huang Treatment of abdominal compartment syndrome in severe acute pancreatitis patients with traditional Chinese medicine World J Gastroenterol 14 2008 3574 3578
6. X.P. Zhang, D.R. Liu, and Y. Shi Study progress in therapeutic effects of traditional Chinese medicine monomer in severe acute pancreatitis J Zhejiang Univ Sci B 8 2007 147 152
7. Y. Qiu, Y.Y. Li, S.G. Li, B.G. Song, and G.F. Zhao Effect of Qingyitang on activity of intracellular Ca2+-Mg2+-ATPase in rats with acute pancreatitis World J Gastroenterol 10 1 2004 100 104
8. Q. Xia, J.M. Jiang, X. Gong, G.Y. Chen, L. Li, and Z.W. Huang Experimental study of Tong Xia purgative method in ameliorating lung injury in acute necrotizing pancreatitis World J Gastroenterol 6 2000 115 118
9. D.F. Gomez-Casati, M.I. Zanor, and M.V. Busi Metabolomics in plants and humans: applications in the prevention and diagnosis of diseases Biomed Res Int 2013 2013 792527
10. T. Zhang, D.G. Watson, L. Wang, M. Abbas, L. Murdoch, L. Bashford, and et al. Application of holistic liquid chromatography-high resolution mass spectrometry based urinary metabolomics for prostate cancer detection and biomarker discovery PLoS One 8 6 2013 e65880
11. A. Zira, S. Kostidis, S. Theocharis, F. Sigala, S.B. Engelsen, I. Andreadou, and et al. 1H NMR-based metabolomics approach in a rat model of acute liver injury and regeneration induced by CCl4 administration Toxicology 303 2013 115 124
12. X. Liang, X. Chen, Q. Liang, H. Zhang, P. Hu, Y. Wang, and et al. Metabonomic study of Chinese medicine Shuanglong formula as an effective treatment for myocardial infarction in rats J Proteome Res 10 2011 790 799
13. J. Wei, G. Xie, S. Ge, Y. Qiu, W. Liu, A. Lu, and et al. Metabolic transformation of DMBA-induced carcinogenesis and inhibitory effect of salvianolic acid b and breviscapine treatment J Proteome Res 11 2012 1302 1316
14. P. Li, L.P. Yang, and Y.W. Gong Application of systems biology technology in research of traditional Chinese medicine J Tradit Chin Med 29 2009 153 157
15. M.A. Fernández-Peralbo, F. Priego-Capote, M.D. Luque de Castro, A. Casado-Adam, A. Arjona-Sánchez, and F.C. Muñoz-Casares LC-MS/MS quantitative analysis of paclitaxel and its major metabolites in serum, plasma and tissue from women with ovarian cancer after intraperitoneal chemotherapy J Pharm Biomed Anal 91C 2014 131 137
16. G. Tan, W. Liao, X. Dong, G. Yang, Z. Zhu, W. Li, and et al. Metabonomic profiles delineate the effect of traditional Chinese medicine sini decoction on myocardial infarction in rats PLoS One 7 4 2012 e34157
17. M.H. Wan, J. Li, W.F. Tang, H.L. Gong, G.Y. Chen, P. Xue, and et al. The influnence of dachengqi tang on acute lung injury and intra abdominal hypertension in rats with acute pancreatitis J Sichuan Univ Med Sci Ed 42 5 2011 707 711
18. S. Trumbeckaite, I. Kuliaviene, O. Deduchovas, M. Kincius, R. Baniene, S. Virketyte, and et al. Experimental acute pancreatitis induces mitochondrial dysfunction in rat pancreas, kidney and lungs but not in liver Pancreatology 13 3 2013 216 224
19. J. Maléth, Z. Rakonczay Jr., V. Venglovecz, N.J. Dolman, and P. Hegyi Central role of mitochondrial injury in the pathogenesis of acute pancreatitis Acta Physiol (Oxf) 207 2 2013 226 235
20. O. Ioannidis, A. Lavrentieva, and D. Botsios Nutrition support in acute pancreatitis JOP 9 2008 375 390
21. R.F. Meier, and C. Beglinger Nutrition in pancreatic diseases Best Pract Res Clin Gastroenterol 20 2006 507 529
22. S.J. O'Keefe, and S.A. McClave Feeding the injured pancreas Gastroenterology 129 2005 1129 1130
23. R. Gupta, K. Patel, P.C. Calder, P. Yaqoob, J.N. Primrose, and C.D. Johnson A randomized clinical trial to assess the effect of total enteral and total parenteral nutritional support on metabolic, inflammatory and oxidative markers in patients with predicted severe acute pancreatitis (APACHE II > or =6) Pancreatology 3 2003 406 413
24. J.H. Shaw, and R.R. Wolfe Glucose, fatty acid, and urea kinetics in patients with severe pancreatitis. The response to substrate infusion and total parenteral nutrition Ann Surg 204 1986 665 672
25. V. Di Carlo, A. Nespoli, R. Chiesa, C. Staudacher, M. Cristallo, G. Bevilacqua, and et al. Hemodynamic and metabolic impairment in acute pancreatitis World J Surg 5 1981 329 339
26. J.P. Vieira, G.F. Araújo, J.R. Azevedo, A. Goldenberg, and M.M. Linhares Parenteral nutrition versus enteral nutrition in severe acute pancreatitis Acta Cir Bras 25 2010 449 454
27. J. Zhao, W. Tang, J. Wang, J. Xiang, H. Gong, and G. Chen Pharmacokinetic and pharmacodynamic studies of four major phytochemical components of Da-Cheng-Qi decoction to treat acute pancreatitis J Pharmacol Sci 122 2 2013 118 127