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Volumn 72, Issue 7, 2015, Pages 678-686

Two patterns of white matter abnormalities in medication-naive patients with first-episode schizophrenia revealed by diffusion tensor imaging and cluster analysis

Author keywords

[No Author keywords available]

Indexed keywords

ADOLESCENT; ADULT; ARTICLE; CLUSTER ANALYSIS; CONTROLLED STUDY; DIFFUSION TENSOR IMAGING; FEMALE; FRACTIONAL ANISOTROPY; HUMAN; IMAGE PROCESSING; MAJOR CLINICAL STUDY; MALE; NEUROIMAGING; NUCLEAR MAGNETIC RESONANCE IMAGING; NUCLEAR MAGNETIC RESONANCE SCANNER; SCHIZOPHRENIA; WHITE MATTER LESION; BRAIN; CASE CONTROL STUDY; COHORT ANALYSIS; DIFFUSION WEIGHTED IMAGING; MIDDLE AGED; NERVE TRACT; PATHOLOGY; WHITE MATTER; YOUNG ADULT;

EID: 84937484628     PISSN: 2168622X     EISSN: None     Source Type: Journal    
DOI: 10.1001/jamapsychiatry.2015.0505     Document Type: Article
Times cited : (130)

References (58)
  • 1
    • 0032502349 scopus 로고    scopus 로고
    • The disconnection hypothesis
    • Friston KJ. The disconnection hypothesis. Schizophr Res. 1998;30(2):115-125.
    • (1998) Schizophr Res , vol.30 , Issue.2 , pp. 115-125
    • Friston, K.J.1
  • 2
    • 0038704983 scopus 로고    scopus 로고
    • Structural disconnectivity in schizophrenia: A diffusion tensor magnetic resonance imaging study
    • Burns J, Job D, Bastin ME, et al. Structural disconnectivity in schizophrenia: a diffusion tensor magnetic resonance imaging study. Br J Psychiatry. 2003;182(5):439-443.
    • (2003) Br J Psychiatry , vol.182 , Issue.5 , pp. 439-443
    • Burns, J.1    Job, D.2    Bastin, M.E.3
  • 3
    • 0035836642 scopus 로고    scopus 로고
    • Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia
    • Hakak Y, Walker JR, Li C, et al. Genome-wide expression analysis reveals dysregulation of myelination-related genes in chronic schizophrenia. Proc Natl Acad Sci U S A. 2001;98(8):4746-4751.
    • (2001) Proc Natl Acad Sci U S A , vol.98 , Issue.8 , pp. 4746-4751
    • Hakak, Y.1    Walker, J.R.2    Li, C.3
  • 4
    • 0038643584 scopus 로고    scopus 로고
    • White matter changes in schizophrenia: Evidence for myelin-related dysfunction
    • Davis KL, Stewart DG, Friedman JI, et al. White matter changes in schizophrenia: evidence for myelin-related dysfunction. Arch Gen Psychiatry. 2003;60(5):443-456.
    • (2003) Arch Gen Psychiatry , vol.60 , Issue.5 , pp. 443-456
    • Davis, K.L.1    Stewart, D.G.2    Friedman, J.I.3
  • 5
    • 10744226835 scopus 로고    scopus 로고
    • Abnormalities ofmyelination in schizophrenia detected in vivo with MRI, and post-mortem with analysis of oligodendrocyte proteins
    • Flynn SW, Lang DJ, Mackay AL, et al. Abnormalities ofmyelination in schizophrenia detected in vivo with MRI, and post-mortem with analysis of oligodendrocyte proteins. Mol Psychiatry. 2003;8(9):811-820.
    • (2003) Mol Psychiatry , vol.8 , Issue.9 , pp. 811-820
    • Flynn, S.W.1    Lang, D.J.2    Mackay, A.L.3
  • 6
    • 0033955452 scopus 로고    scopus 로고
    • Decreased density of tyrosine hydroxylaseimmunoreactive axons in the entorhinal cortex of schizophrenic subjects
    • AkilM, Edgar CL, Pierri JN, Casali S, Lewis DA. Decreased density of tyrosine hydroxylaseimmunoreactive axons in the entorhinal cortex of schizophrenic subjects. Biol Psychiatry. 2000;47 (5):361-370.
    • (2000) Biol Psychiatry , vol.47 , Issue.5 , pp. 361-370
    • Akilm Edgar, C.L.1    Pierri, J.N.2    Casali, S.3    Lewis, D.A.4
  • 7
    • 33745188219 scopus 로고    scopus 로고
    • Tract-based spatial statistics: Voxelwise analysis of multi-subject diffusion data
    • Smith SM, Jenkinson M, Johansen-Berg H, et al. Tract-based spatial statistics: voxelwise analysis of multi-subject diffusion data. Neuroimage. 2006;31 (4):1487-1505.
    • (2006) Neuroimage , vol.31 , Issue.4 , pp. 1487-1505
    • Smith, S.M.1    Jenkinson, M.2    Johansen-Berg, H.3
  • 8
    • 0036235198 scopus 로고    scopus 로고
    • Uncinate fasciculus findings in schizophrenia: Amagnetic resonance diffusion tensor imaging study
    • Kubicki M, Westin C-F, Maier SE, et al. Uncinate fasciculus findings in schizophrenia: amagnetic resonance diffusion tensor imaging study. Am J Psychiatry. 2002;159(5):813-820.
    • (2002) Am J Psychiatry , vol.159 , Issue.5 , pp. 813-820
    • Kubicki, M.1    Westin, C.-F.2    Maier, S.E.3
  • 9
    • 10744229694 scopus 로고    scopus 로고
    • Cingulate fasciculus integrity disruption in schizophrenia: Amagnetic resonance diffusion tensor imaging study
    • Kubicki M, Westin C-F, Nestor PG, et al. Cingulate fasciculus integrity disruption in schizophrenia: amagnetic resonance diffusion tensor imaging study. Biol Psychiatry. 2003;54(11):1171-1180.
    • (2003) Biol Psychiatry , vol.54 , Issue.11 , pp. 1171-1180
    • Kubicki, M.1    Westin, C.-F.2    Nestor, P.G.3
  • 10
    • 33745445370 scopus 로고    scopus 로고
    • Fornix integrity and hippocampal volume in male schizophrenic patients
    • Kuroki N, Kubicki M, Nestor PG, et al. Fornix integrity and hippocampal volume in male schizophrenic patients. Biol Psychiatry. 2006;60 (1):22-31.
    • (2006) Biol Psychiatry , vol.60 , Issue.1 , pp. 22-31
    • Kuroki, N.1    Kubicki, M.2    Nestor, P.G.3
  • 11
    • 47249103395 scopus 로고    scopus 로고
    • Disrupted integrity of the fornix is associated with impaired memory organization in schizophrenia
    • Takei K, Yamasue H, Abe O, et al. Disrupted integrity of the fornix is associated with impaired memory organization in schizophrenia. Schizophr Res. 2008;103(1-3):52-61.
    • (2008) Schizophr Res , vol.103 , Issue.1-3 , pp. 52-61
    • Takei, K.1    Yamasue, H.2    Abe, O.3
  • 13
    • 35948965593 scopus 로고    scopus 로고
    • Disruption of white matter integrity in the inferior longitudinal fasciculus in adolescents with schizophrenia as revealed by fiber tractography
    • Ashtari M, Cottone J, Ardekani BA, et al. Disruption of white matter integrity in the inferior longitudinal fasciculus in adolescents with schizophrenia as revealed by fiber tractography. Arch Gen Psychiatry. 2007;64(11):1270-1280.
    • (2007) Arch Gen Psychiatry , vol.64 , Issue.11 , pp. 1270-1280
    • Ashtari, M.1    Cottone, J.2    Ardekani, B.A.3
  • 14
    • 0035972740 scopus 로고    scopus 로고
    • Diffusion tensor imaging (DTI) and proton magnetic resonance spectroscopy (1H MRS) in schizophrenic subjects and normal controls
    • Steel RM, Bastin ME, McConnell S, et al. Diffusion tensor imaging (DTI) and proton magnetic resonance spectroscopy (1H MRS) in schizophrenic subjects and normal controls. Psychiatry Res. 2001; 106(3):161-170.
    • (2001) Psychiatry Res , vol.106 , Issue.3 , pp. 161-170
    • Steel, R.M.1    Bastin, M.E.2    McConnell, S.3
  • 15
    • 0043157821 scopus 로고    scopus 로고
    • A diffusion tensor imaging study of middle and superior cerebellar peduncle in male patients with schizophrenia
    • Wang F, Sun Z, Du X, et al. A diffusion tensor imaging study of middle and superior cerebellar peduncle in male patients with schizophrenia. Neurosci Lett. 2003;348(3):135-138.
    • (2003) Neurosci Lett , vol.348 , Issue.3 , pp. 135-138
    • Wang, F.1    Sun, Z.2    Du, X.3
  • 17
    • 79959736768 scopus 로고    scopus 로고
    • Voxel-based morphometry (VBM) studies in schizophrenia-can white matter changes be reliably detected with VBM?
    • Melonakos ED, Shenton ME, Rathi Y, Terry DP, Bouix S, Kubicki M. Voxel-based morphometry (VBM) studies in schizophrenia-can white matter changes be reliably detected with VBM? Psychiatry Res. 2011;193(2):65-70.
    • (2011) Psychiatry Res , vol.193 , Issue.2 , pp. 65-70
    • Melonakos, E.D.1    Shenton, M.E.2    Rathi, Y.3    Terry, D.P.4    Bouix, S.5    Kubicki, M.6
  • 19
    • 72549098658 scopus 로고    scopus 로고
    • Functional and anatomical connectivity abnormalities in left inferior frontal gyrus in schizophrenia
    • Jeong B, Wible CG, Hashimoto R, Kubicki M. Functional and anatomical connectivity abnormalities in left inferior frontal gyrus in schizophrenia. Hum Brain Mapp. 2009;30(12): 4138-4151.
    • (2009) Hum Brain Mapp , vol.30 , Issue.12 , pp. 4138-4151
    • Jeong, B.1    Wible, C.G.2    Hashimoto, R.3    Kubicki, M.4
  • 20
    • 34548262723 scopus 로고    scopus 로고
    • Anatomically related grey and white matter abnormalities in adolescent-onset schizophrenia
    • Douaud G, Smith S, Jenkinson M, et al. Anatomically related grey and white matter abnormalities in adolescent-onset schizophrenia. Brain. 2007;130(pt 9):2375-2386.
    • (2007) Brain , vol.130 , pp. 2375-2386
    • Douaud, G.1    Smith, S.2    Jenkinson, M.3
  • 21
    • 84872383738 scopus 로고    scopus 로고
    • Extensive white matter abnormalities in patients with first-episode schizophrenia: A diffusion tensor imaging (DTI) study
    • Lee S-H, Kubicki M, Asami T, et al. Extensive white matter abnormalities in patients with first-episode schizophrenia: a diffusion tensor imaging (DTI) study. Schizophr Res. 2013;143(2-3): 231-238.
    • (2013) Schizophr Res , vol.143 , Issue.2-3 , pp. 231-238
    • Lee, S.-H.1    Kubicki, M.2    Asami, T.3
  • 22
    • 84894106267 scopus 로고    scopus 로고
    • Altered interhemispheric and temporal lobe white mattermicrostructural organization in severe chronic schizophrenia
    • Holleran L, Ahmed M, Anderson-Schmidt H, et al. Altered interhemispheric and temporal lobe white mattermicrostructural organization in severe chronic schizophrenia. Neuropsychopharmacology. 2014;39(4):944-954.
    • (2014) Neuropsychopharmacology , vol.39 , Issue.4 , pp. 944-954
    • Holleran, L.1    Ahmed, M.2    Anderson-Schmidt, H.3
  • 23
    • 84879735936 scopus 로고    scopus 로고
    • Reduced white matter integrity and cognitive deficit in never-medicated chronic schizophrenia: A diffusion tensor study using TBSS
    • Liu X, Lai Y, Wang X, et al. Reduced white matter integrity and cognitive deficit in never-medicated chronic schizophrenia: a diffusion tensor study using TBSS. Behav Brain Res. 2013; 252:157-163.
    • (2013) Behav Brain Res , vol.252 , pp. 157-163
    • Liu, X.1    Lai, Y.2    Wang, X.3
  • 25
    • 60249093730 scopus 로고    scopus 로고
    • Meta-analysis of diffusion tensor imaging studies in schizophrenia
    • Ellison-Wright I, Bullmore E. Meta-analysis of diffusion tensor imaging studies in schizophrenia. Schizophr Res. 2009;108(1-3):3-10.
    • (2009) Schizophr Res , vol.108 , Issue.1-3 , pp. 3-10
    • Ellison-Wright, I.1    Bullmore, E.2
  • 26
    • 84855995824 scopus 로고    scopus 로고
    • Reduced left uncinate fasciculus fractional anisotropy in deficit schizophrenia but not in non-deficit schizophrenia
    • Kitis O, Ozalay O, Zengin EB, et al. Reduced left uncinate fasciculus fractional anisotropy in deficit schizophrenia but not in non-deficit schizophrenia. Psychiatry Clin Neurosci. 2012;66(1):34-43.
    • (2012) Psychiatry Clin Neurosci , vol.66 , Issue.1 , pp. 34-43
    • Kitis, O.1    Ozalay, O.2    Zengin, E.B.3
  • 28
    • 84876921255 scopus 로고    scopus 로고
    • Neuroimaging evidence for the deficit subtype of schizophrenia
    • Voineskos AN, Foussias G, Lerch J, et al. Neuroimaging evidence for the deficit subtype of schizophrenia. JAMAPsychiatry. 2013;70(5):472-480.
    • (2013) JAMAPsychiatry , vol.70 , Issue.5 , pp. 472-480
    • Voineskos, A.N.1    Foussias, G.2    Lerch, J.3
  • 29
    • 84869086009 scopus 로고    scopus 로고
    • Right lateralized white matter abnormalities in first-episode, drug-naive paranoid schizophrenia
    • Guo W, Liu F, Liu Z, et al. Right lateralized white matter abnormalities in first-episode, drug-naive paranoid schizophrenia. Neurosci Lett. 2012;531(1): 5-9.
    • (2012) Neurosci Lett , vol.531 , Issue.1 , pp. 5-9
    • Guo, W.1    Liu, F.2    Liu, Z.3
  • 31
    • 79951503453 scopus 로고    scopus 로고
    • Long-term antipsychotic treatment and brain volumes: A longitudinal study of first-episode schizophrenia
    • Ho B-C, Andreasen NC, Ziebell S, Pierson R, Magnotta V. Long-term antipsychotic treatment and brain volumes: a longitudinal study of first-episode schizophrenia. Arch Gen Psychiatry. 2011;68(2):128-137.
    • (2011) Arch Gen Psychiatry , vol.68 , Issue.2 , pp. 128-137
    • Ho, B.-C.1    Andreasen, N.C.2    Ziebell, S.3    Pierson, R.4    Magnotta, V.5
  • 33
    • 84869127194 scopus 로고    scopus 로고
    • Tract profiles of white matter properties: Automating fiber-tract quantification
    • Yeatman JD, Dougherty RF, Myall NJ, Wandell BA, Feldman HM. Tract profiles of white matter properties: automating fiber-tract quantification. PLoS One. 2012;7(11):e49790.
    • (2012) PLoS One , vol.7 , Issue.11 , pp. e49790
    • Yeatman, J.D.1    Dougherty, R.F.2    Myall, N.J.3    Wandell, B.A.4    Feldman, H.M.5
  • 35
    • 0014129195 scopus 로고
    • Hierarchical clustering schemes
    • Johnson SC. Hierarchical clustering schemes. Psychometrika. 1967;32(3):241-254.
    • (1967) Psychometrika , vol.32 , Issue.3 , pp. 241-254
    • Johnson, S.C.1
  • 36
    • 0023453329 scopus 로고
    • Silhouettes: A graphical aid to the interpretation and validation of cluster analysis
    • Rousseeuw PJ. Silhouettes: a graphical aid to the interpretation and validation of cluster analysis. J Comput Appl Math. 1987;20:53-65.
    • (1987) J Comput Appl Math , vol.20 , pp. 53-65
    • Rousseeuw, P.J.1
  • 37
    • 0015644825 scopus 로고
    • A fuzzy relative of the ISODATA process and its use in detecting compact well-separated clusters
    • Dunn JC. A fuzzy relative of the ISODATA process and its use in detecting compact well-separated clusters. J Cybern. 1973;3(3):32-57. doi:10.1080/01969727308546046.
    • (1973) J Cybern , vol.3 , Issue.3 , pp. 32-57
    • Dunn, J.C.1
  • 39
    • 0142057962 scopus 로고    scopus 로고
    • Detecting stable clusters using principal component analysis
    • Ben-Hur A, Guyon I. Detecting stable clusters using principal component analysis. Methods Mol Biol. 2003;224(1):159-182.
    • (2003) Methods Mol Biol , vol.224 , Issue.1 , pp. 159-182
    • Ben-Hur, A.1    Guyon, I.2
  • 40
    • 84931957507 scopus 로고    scopus 로고
    • A review of structural neuroimaging in schizophrenia: From connectivity to connectomics
    • Wheeler AL, Voineskos AN. A review of structural neuroimaging in schizophrenia: from connectivity to connectomics. Front Hum Neurosci. 2014;8:653.
    • (2014) Front Hum Neurosci , vol.8 , pp. 653
    • Wheeler, A.L.1    Voineskos, A.N.2
  • 42
    • 37249094173 scopus 로고    scopus 로고
    • From inflammation to sickness and depression: When the immune system subjugates the brain
    • Dantzer R, O'Connor JC, Freund GG, Johnson RW, Kelley KW. From inflammation to sickness and depression: when the immune system subjugates the brain. Nat Rev Neurosci. 2008;9(1):46-56.
    • (2008) Nat Rev Neurosci , vol.9 , Issue.1 , pp. 46-56
    • Dantzer, R.1    O'Connor, J.C.2    Freund, G.G.3    Johnson, R.W.4    Kelley, K.W.5
  • 43
    • 40949107708 scopus 로고    scopus 로고
    • Inflammatory cytokine alterations in schizophrenia: A systematic quantitative review
    • Potvin S, Stip E, Sepehry AA, Gendron A, Bah R, Kouassi E. Inflammatory cytokine alterations in schizophrenia: a systematic quantitative review. Biol Psychiatry. 2008;63(8):801-808.
    • (2008) Biol Psychiatry , vol.63 , Issue.8 , pp. 801-808
    • Potvin, S.1    Stip, E.2    Sepehry, A.A.3    Gendron, A.4    Bah, R.5    Kouassi, E.6
  • 44
    • 84870160951 scopus 로고    scopus 로고
    • Excessive extracellular volume reveals a neurodegenerative pattern in schizophrenia onset
    • Pasternak O, Westin C-F, Bouix S, et al. Excessive extracellular volume reveals a neurodegenerative pattern in schizophrenia onset. J Neurosci. 2012;32(48):17365-17372.
    • (2012) J Neurosci , vol.32 , Issue.48 , pp. 17365-17372
    • Pasternak, O.1    Westin, C.-F.2    Bouix, S.3
  • 45
    • 55949130305 scopus 로고    scopus 로고
    • Diffusion in brain extracellular space
    • Syková E, Nicholson C. Diffusion in brain extracellular space. Physiol Rev. 2008;88(4):1277-1340.
    • (2008) Physiol Rev , vol.88 , Issue.4 , pp. 1277-1340
    • Syková, E.1    Nicholson, C.2
  • 46
    • 37149001493 scopus 로고    scopus 로고
    • Disturbed structural connectivity in schizophrenia primary factor in pathology or epiphenomenon?
    • Konrad A, Winterer G. Disturbed structural connectivity in schizophrenia primary factor in pathology or epiphenomenon? Schizophr Bull. 2008;34(1):72-92.
    • (2008) Schizophr Bull , vol.34 , Issue.1 , pp. 72-92
    • Konrad, A.1    Winterer, G.2
  • 47
    • 21044459635 scopus 로고    scopus 로고
    • Mapping cortical thickness and gray matter concentration in first episode schizophrenia
    • Narr KL, Bilder RM, Toga AW, et al. Mapping cortical thickness and gray matter concentration in first episode schizophrenia. Cereb Cortex. 2005;15 (6):708-719.
    • (2005) Cereb Cortex , vol.15 , Issue.6 , pp. 708-719
    • Narr, K.L.1    Bilder, R.M.2    Toga, A.W.3
  • 48
    • 0036894419 scopus 로고    scopus 로고
    • Smaller frontal gray matter volume in postmortem schizophrenic brains
    • Selemon LD, Kleinman JE, Herman MM, Goldman-Rakic PS. Smaller frontal gray matter volume in postmortem schizophrenic brains. Am J Psychiatry. 2002;159(12):1983-1991.
    • (2002) Am J Psychiatry , vol.159 , Issue.12 , pp. 1983-1991
    • Selemon, L.D.1    Kleinman, J.E.2    Herman, M.M.3    Goldman-Rakic, P.S.4
  • 49
    • 84900453362 scopus 로고    scopus 로고
    • Neuronal activity promotes oligodendrogenesis and adaptivemyelination in the mammalian brain
    • Gibson EM, Purger D, Mount CW, et al. Neuronal activity promotes oligodendrogenesis and adaptivemyelination in the mammalian brain. Science. 2014;344(6183):1252304.
    • (2014) Science , vol.344 , Issue.6183 , pp. 1252304
    • Gibson, E.M.1    Purger, D.2    Mount, C.W.3
  • 50
    • 84869021660 scopus 로고    scopus 로고
    • White matter development in adolescence: Diffusion tensor imaging and meta-analytic results
    • Peters BD, Szeszko PR, Radua J, et al. White matter development in adolescence: diffusion tensor imaging and meta-analytic results. Schizophr Bull. 2012;38(6):1308-1317.
    • (2012) Schizophr Bull , vol.38 , Issue.6 , pp. 1308-1317
    • Peters, B.D.1    Szeszko, P.R.2    Radua, J.3
  • 51
    • 84920661999 scopus 로고    scopus 로고
    • White matter development in the early stages of psychosis
    • Peters BD, Karlsgodt KH. White matter development in the early stages of psychosis. Schizophr Res. 2015;161(1):61-69.
    • (2015) Schizophr Res , vol.161 , Issue.1 , pp. 61-69
    • Peters, B.D.1    Karlsgodt, K.H.2
  • 52
    • 84865176025 scopus 로고    scopus 로고
    • Reduced white matter fractional anisotropy and clinical symptoms in schizophrenia: A voxel-based diffusion tensor imaging study
    • Nakamura K, Kawasaki Y, Takahashi T, et al. Reduced white matter fractional anisotropy and clinical symptoms in schizophrenia: a voxel-based diffusion tensor imaging study. Psychiatry Res. 2012;202(3):233-238.
    • (2012) Psychiatry Res , vol.202 , Issue.3 , pp. 233-238
    • Nakamura, K.1    Kawasaki, Y.2    Takahashi, T.3
  • 53
    • 40549095373 scopus 로고    scopus 로고
    • Clinical and neuropsychological correlates of white matter abnormalities in recent onset schizophrenia
    • Szeszko PR, Robinson DG, AshtariM, et al. Clinical and neuropsychological correlates of white matter abnormalities in recent onset schizophrenia. Neuropsychopharmacology. 2008;33(5):976-984.
    • (2008) Neuropsychopharmacology , vol.33 , Issue.5 , pp. 976-984
    • Szeszko, P.R.1    Robinson, D.G.2    Ashtari, M.3
  • 54
    • 34147122016 scopus 로고    scopus 로고
    • Internal capsule, corpus callosum and long associative fibers in good and poor outcome schizophrenia: A diffusion tensor imaging survey
    • Mitelman SA, Torosjan Y, Newmark RE, et al. Internal capsule, corpus callosum and long associative fibers in good and poor outcome schizophrenia: a diffusion tensor imaging survey. Schizophr Res. 2007;92(1-3):211-224.
    • (2007) Schizophr Res , vol.92 , Issue.1-3 , pp. 211-224
    • Mitelman, S.A.1    Torosjan, Y.2    Newmark, R.E.3
  • 55
    • 0035142528 scopus 로고    scopus 로고
    • Structural abnormalities in frontal, temporal, and limbic regions and interconnecting white matter tracts in schizophrenic patients with prominent negative symptoms
    • Sigmundsson T, Suckling J, Maier M, et al. Structural abnormalities in frontal, temporal, and limbic regions and interconnecting white matter tracts in schizophrenic patients with prominent negative symptoms. Am J Psychiatry. 2001;158(2): 234-243.
    • (2001) Am J Psychiatry , vol.158 , Issue.2 , pp. 234-243
    • Sigmundsson, T.1    Suckling, J.2    Maier, M.3
  • 56
    • 79960608289 scopus 로고    scopus 로고
    • Inflammatory processes in schizophrenia: A promising neuroimmunological target for the treatment of negative/cognitive symptoms and beyond
    • Meyer U, Schwarz MJ, Müller N. Inflammatory processes in schizophrenia: a promising neuroimmunological target for the treatment of negative/cognitive symptoms and beyond. Pharmacol Ther. 2011;132(1):96-110.
    • (2011) Pharmacol Ther , vol.132 , Issue.1 , pp. 96-110
    • Meyer, U.1    Schwarz, M.J.2    Müller, N.3
  • 58
    • 77954230363 scopus 로고    scopus 로고
    • Research domain criteria (RDoC): Toward a new classification framework for research on mental disorders
    • Insel T, Cuthbert B, GarveyM, et al. Research domain criteria (RDoC): toward a new classification framework for research on mental disorders. Am J Psychiatry. 2010;167(7):748-751.
    • (2010) Am J Psychiatry , vol.167 , Issue.7 , pp. 748-751
    • Insel, T.1    Cuthbert, B.2    Garvey, M.3


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