Reduced airway microbiota diversity is associated with elevated allergic respiratory inflammation

Annals of Allergy, Asthma and Immunology

Volumn 115, Issue 1, 2015, Pages 63-68

  Yu, Wenkai ^a,b   Yuan, Xiaopeng ^a   Xu, Xingche ^a   Ding, Rui ^a   Pang, Liyuan ^a   Liu, Yinhui ^a   Guo, Yanjie ^a   Li, Huajun ^a   Li, Ming ^a   Yuan, Jieli ^a   Tang, Li ^a   Wen, Shu ^a  

^a DALIAN MEDICAL UNIVERSITY   (China)

^b Jining No 1 People's Hospital   (China)

Author keywords

[No Author keywords available]

Indexed keywords

IMMUNOGLOBULIN E; OVALBUMIN; ALLERGEN; CHEMOKINE; MESSENGER RNA;

ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; ASTHMA; BACTEROIDETES; CELL INFILTRATION; CONTROLLED STUDY; HYGIENE; IMMUNOGLOBULIN PRODUCTION; LEUKOCYTE COUNT; MICROBIAL COMMUNITY; MICROBIAL DIVERSITY; NONHUMAN; PRIORITY JOURNAL; PROTEOBACTERIA; RAT; SNEEZING; ANIMAL; BIOSYNTHESIS; DISEASE PREDISPOSITION; GENETICS; GERMFREE ANIMAL; IMMUNIZATION; IMMUNOLOGICAL TOLERANCE; IMMUNOLOGY; INCIDENCE; MICROBIOLOGY; MICROFLORA; RESPIRATORY HYPERSENSITIVITY; RESPIRATORY SYSTEM; SUBCUTANEOUS DRUG ADMINISTRATION; SYMBIOSIS; WISTAR RAT;

ALLERGENS; ANIMALS; CHEMOKINES; DISEASE SUSCEPTIBILITY; IMMUNE TOLERANCE; IMMUNIZATION; INCIDENCE; INJECTIONS, SUBCUTANEOUS; MICROBIOTA; OVALBUMIN; RATS; RATS, WISTAR; RESPIRATORY HYPERSENSITIVITY; RESPIRATORY SYSTEM; RNA, MESSENGER; SPECIFIC PATHOGEN-FREE ORGANISMS; SYMBIOSIS;

EID: 84937414597     PISSN: 10811206     EISSN: 15344436     Source Type: Journal    
DOI: 10.1016/j.anai.2015.04.025     Document Type: Article

References (23)

1. T.T. Hansel, S.L. Johnston, and P.J. Openshaw Microbes and mucosal immune responses in asthma Lancet 381 2013 861 873
2. C.M. Lloyd, and J.R. Murdoch Tolerizing allergic responses in the lung Mucosal Immunol 3 2010 334 344
3. G.G. Brusselle, T. Maes, and K.R. Bracke Eosinophilic airway inflammation in nonallergic asthma Nat Med 19 2013 977 979
4. 2-agonists, improve the perception of bronchoconstriction in asthma Am J Respir Crit Care Med 164 2001 764 769
5. M. Masoli, D. Fabian, S. Holt, and R. Beasley Global Initiative for Asthma (GINA) Program. The global burden of asthma: executive summary of the GINA Dissemination Committee Report Allergy 59 2004 469 478
6. M.I. Asher Recent perspectives on global epidemiology of asthma in childhood Allergol Immunopathol (Madr) 38 2010 83 87
7. M.J. Ege, M. Mayer, A.C. Normand, and et al. Exposure to environmental microorganisms and childhood asthma N Engl J Med 364 2011 701 709
8. D.P. Strachan Hay fever, hygiene, and household size BMJ 299 1989 1259 1260
9. J. Riedler, C. Braun-Fahrländer, W. Eder, M. Schreuer, M. Waser, and S. Maisch Exposure to farming in early life and development of asthma and allergy: a cross-sectional survey Lancet 358 2001 1129 1133
10. M. Bendiks, and M.V. Kopp The relationship between advances in understanding the microbiome and the maturing hygiene hypothesis Curr Allergy Asthma Rep 13 2013 487 494
11. T. Herbst, A. Sichelstiel, and C. Schär Dysregulation of allergic airway inflammation in the absence of microbial colonization Am J Respir Crit Care Med 184 2011 198 205
12. S.L. Russell, M.J. Gold, and M. Hartmann Early life antibiotic-driven changes in microbiota enhance susceptibility to allergic asthma EMBO Rep 13 2012 440 447
13. M.R. Edwards, N.W. Bartlett, T. Hussell, P. Openshaw, and S.L. Johnston The microbiology of asthma Nat Rev Microbiol 10 2012 459 471
14. S.L. Russell, and B.B. Finlay The impact of gut microbes in allergic diseases Curr Opin Gastroenterol 28 2012 563 569
15. H. Bisgaard, M.N. Hermansen, F. Buchvald, and et al. Childhood asthma after bacterial colonization of the airway in neonates N Engl J Med 357 2007 1487 1495
16. M. Hilty, C. Burke, H. Pedro, and et al. Disordered microbial communities in asthmatic airways PLoS One 5 2010 e8578
17. Y.J. Huang Asthma microbiome studies and the potential for new therapeutic strategies Curr Allergy Asthma Rep 13 2012 453 461
18. J. Couzin Frankel Bacteria and asthma: untangling the links Science 26 2010 1168 1169
19. D.T. Umetsu Early exposure to germs and the hygiene hypothesis Cell Res 22 2012 1210 1211
20. A.L. Kozyrskyj, S. Bahreinian, and M.B. Azad Early life exposures: impact on asthma and allergic disease Curr Opin Allergy Clin Immunol 11 2011 400 406
21. W. Pang, H. Wang, L. Shi, and et al. Immunomodulatory effects of Escherichia coli ATCC 25922 on allergic airway inflammation in a mouse model PLoS One 8 2013 e59174
22. B.P. Willing, S.L. Russell, and B.B. Finlay Shifting the balance: antibiotic effects on host-microbiota mutualism Nat Rev Microbiol 9 2011 233 243
23. S.L. Russell, M.J. Gold, B.P. Willing, L. Thorson, K.M. McNagny, and B.B. Finlay Perinatal antibiotic treatment affects murine microbiota, immune responses and allergic asthma Gut Microbes 4 2013 158 164